scholarly journals Clinico-Pathological study of carcinoma breast in a tertiary care hospital from West Bengal, India: A Cross-Sectional Observational study

2021 ◽  
Vol 12 (9) ◽  
pp. 75-78
Author(s):  
Deepak Kumar Sahoo ◽  
Mintu Mohan Nandi ◽  
Srijan Basu ◽  
Sanjay Chatterjee ◽  
Amit Kumar Das

Background: Breast cancer is one of the most common cancer in women. BC represents a heterogeneous group of tumors that are diverse in behavior, outcome, and response to therapy. Aims and Objective: The present study was undertaken to assess various clinical parameters and to evaluate correlation with histo-pathological grading in breast carcinoma patients. Materials and Methods: The study was conducted in the Surgical outpatient department and Indoor surgical wards of Deben Mahato Sadar Hospital (DMSH), Purulia, West Bengal from July, 2019 to December, 2020. 104 patients with diagnosis of BC aged between 20 years to 80 years were selected. Results: Among 104 patients, 41.3% patients were in the group of 41-50years. This study revealed that the patient had mostly IDC i.e. 78.8% and had triple negative BC (51.9%). Association of HPE vs. Stage, subtypes vs stage and Tru-cut biopsy vs HPE were statistically significant. Conclusion: The study showed that breast cancer tends to present in middle aged women and positively correlate with the present markers of bad prognosis.

Author(s):  
Anjan Adhikari ◽  
Dipesh Chakraborty ◽  
Rania Indu ◽  
Sangita Bhattacharya ◽  
Moumita Ray ◽  
...  

 Objective: Cancer is a disease of uncontrolled division of cells in any part of the body. Breast cancer most common in women accounts for 13% of the death worldwide. The objective of the present study was to evaluate the drug prescription pattern of breast carcinoma patients in a tertiary care hospital of West Bengal.Methods: This was a cross-sectional observational questionnaire-based study done for a period of 6 months at the Department of Pharmacology in Collaboration with the Department of Surgery and Department of Radiotherapy of a Tertiary Care Hospital at Kolkata, West Bengal, India. Female patients with breast cancer (originated from epithelial tissues) of different types and grade attending surgery outdoor patient department were taken as subjects for the study, after signing informed consent.Results: The present study evaluated 28 patients (n=28) diagnosed as breast cancer by the physicians of the department of surgery and radiotherapy. It was observed that breast cancer was mostly found in the middle age group. Breast carcinoma in postmenopausal women accounted to 75%. The most prevalent breast cancer was invasive ductal carcinoma, accounting to 75% of the study population. 5-Fluorouracil, epirubicin, doxorubicin, cyclophosphamide, docetaxel/paclitaxel, and carboplatin were mostly used as chemotherapeutic agent.Conclusion: Breast carcinoma being a prevalent type of cancer in females, the present study tried to evaluate the pattern of prescribing chemotherapeutic agents for breast cancer patients in a tertiary care hospital. Such study is essential to evaluate and refine the therapeutic regimen of the cancer patients to reduce their sufferings.


Author(s):  
Nandini Chatterjee ◽  
Supratick Chakraborty ◽  
Mainak Mukhopadhyay ◽  
Sinjon Ghosh ◽  
Bikramjit Barkandaj ◽  
...  

2021 ◽  
pp. 12-15
Author(s):  
Smarajit Banik ◽  
Sandip Saha ◽  
Sudipan Mitra ◽  
Ujjwal Pattanayak ◽  
Rajib Sikder ◽  
...  

Background: Diabetes mellitus is one of the important causes of morbidity and mortality. With a rise in non communicable diseases in India, diabetes has become a modern epidemic showing a rising trend in West Bengal also. A large number of diabetes patients come to the diabetes clinic of our tertiary care hospital in North Bengal Medical College and Hospital, Darjeeling, West Bengal. The large proportion of patients presenting with this condition prompted us to study the Sociodemographic and Anthropometric Prole of such patients. Methods: This was a descriptive hospital based cross sectional study involving a total of 344 diabetic patients enrolled in the diabetes clinic of a tertiary care teaching hospital from December 2019 to February 2020. A self-administered questionnaire was used to collect data and was analyzed in Microsoft excel sheet and using SPSS 20.0 software. Results: Among the 344 study participants, we found that 220 (63.95%) were males and 124 (36.05%) were females. Diabetes was more common among those aged 51-60 years 108 (31.40%). Family history was present among 188 (54.65%) of the diabetic patients. Almost 160 (46.51%) patients have diabetes 1.1 – 5 years. Hypertension was present among 216 (62.79%) patients. Almost 218 (63.37%) of the patients were overweight and 84 (24.42%) were obese. Conclusions: The diabetic patients presenting to this tertiary care hospital belong lower socioeconomic strata and having limited education in their age group. There is high proportion of obesity and hypertension among them.


Author(s):  
Alapan Bandyopadhyay ◽  
Debdut Dhar ◽  
Abhijit Mukherjee ◽  
Sharmistha Bhattacherjee ◽  
Samir Dasgupta

Background: Irrational prescription practices are a distressing global problem, especially in the developing countries. A study was conducted to assess the patterns of prescribing and dispensing drugs in a tertiary healthcare centre serving a large rural population in the eastern India.Methods: A cross-sectional observational study was conducted from July-September 2016 in the general out-patient department and the institution pharmacy of a tertiary care hospital of West Bengal, India. Data were congregated by collection and review of individual prescriptions, measuring the time of interaction between patients and prescribers/dispensers, and conducting patient interviews at exit.Results: Analysis of the collected and tabulated data revealed that after average, 2.5 medicines were prescribed per prescription, with 95.26% being under their generic name. Of the drugs prescribed, 95.79% were from the essential drug list. The average consultation time was 150.0s (SD 62.3s) and average dispensing time was 81.5s (SD 51.2s). Of the drugs prescribed, 86.12% of drugs were actually dispensed from the institution pharmacy but none of the drugs were labeled. The percentage of prescriptions with an antibiotic was 47.83%, while injections were recorded on in 2.83% of the prescriptions. Percentage of patients who had knowledge of the dosage of the drugs prescribed to them was 91.67%.Conclusions: While the study found high percentages of drugs prescribed under generic names high percentage of drugs actually prescribed from the Institution Pharmacy, prescription of drugs from the Essential Drugs List, and a low number of injections per prescription conforming to WHO set standards, it also found a lack of drug labelling, high percentage of prescription of antibiotics to be indicators that do not conform with the WHO set international standards.


Author(s):  
Sanjoy Kumar Kunti ◽  
Santanu Ghosh ◽  
Amrita Samanta ◽  
Indranil Chakraborty

Background: Metabolic syndrome (MS) is a pre-condition for cardiovascular diseases and type 2 diabetes mellitus (T2DM) which are major contributors to morbidity and mortality worldwide.Methods: The cross-sectional, observational study was conducted to estimate the proportion of MS and to explore crucial risk factors for MS among adult patients attending medicine OPD in a tertiary care hospital in West Bengal. The estimated final sample size was 315. Baseline socio demographic information and information on risk factors for MS, such as dietary habit, physical activity status, substance use, intake of related drugs, and presence of co-morbidities were collected by interviewing the patients with the help of a predesigned, pretested, structured schedule. Anthropometric measurements such as weight, height, waist circumference recordings were taken, and blood pressure was measured.Results: About 64% of the final study population (210/330) suffered from MS. On bivariate analysis, significant association between female gender (df=1, Pearson chi-square=5.06, p=0.024), weekly frequency of consumption of junk foods (df=3, Pearson chi-square=10.40, p=0.015) and obesity according to BMI (independent samples Mann-Whitney U test, p=0.010) at 5% level of significance were observed. Performing binary logistic regression analysis, obesity according to BMI (AOR=1.388, 95% CI=1.064-1.810) was found to be significant.Conclusions: Majority of the population suffered from MS who were mostly female, obese and consumers of junk foods. Appropriate interventional measures in terms of life style modification both at community and at tertiary care level are the need of the hour.


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