scholarly journals Formulation and Evaluation of Antibacterial and Antioxidant Polyherbal Lotion

2016 ◽  
Vol 21 (1) ◽  
pp. 148-156
Author(s):  
Rajendra Gyawali ◽  
Nira Paudel ◽  
Sahana Shrestha ◽  
Ashok Silwal

There is increased scientific evidence that plants possess a vast and complex arsenal of active ingredients which have the ability to calm or smooth the skin as well as restore actively, heal and protect the skin. The present work deals with the development and evaluation of the poly herbal lotion containing Trigonella foenum-graecum, Citrus lemon, Matricaria chamomilla and Cymbopogon citrates. Different types of formulations oil in water (O/W) herbal lotions namely F1 to F13 were formulated by incorporating different concentrations of stearic acid and Triethanolamine. Formulation of Triethanolamine and stearic acid was optimized as 2.52:9.35. The prepared lotion was evaluated for its antimicrobial, antioxidant and pharmaceutical parameters. The lotion formulation showed no redness, edema, inflammation and irritation during sensitivity test indication that it is safe to use. Stability studies of the lotion showed that the lotion was stable after three months.Journal of Institute of Science and TechnologyVolume 21, Issue 1, August 2016, Page: 148-156

2021 ◽  
Author(s):  
Awais Abbas ◽  
Sadaf Sarfraz ◽  
Umer Younas ◽  
Dr Muhammad Pervaiz Bhatti ◽  
Shahid Hussain ◽  
...  

2020 ◽  
Vol 2 (2(May-August)) ◽  
pp. e342020
Author(s):  
Luciano Lopes Furlanetti ◽  
Matheus Fernando Manzolli Ballestero ◽  
Ricardo Santos De Oliveira

Introduction: Hydrocephalus is the most common neurosurgical condition among children worldwide and shunt diversion of the cerebral-spinal fluid (CSF) has been widely available. The aim of the present study was to perform a systematic review on types and models of shunt devices available and critically evaluate scientific evidence in favor of the usage of specific technologies. Methods: Searches of the PubMed database were performed for relevant articles published from until March 2020. Appropriate keywords were used to identify all studies, including: “shunt”, “technology”, “hydrocephalus”, “children”, “pediatric”. The indications and scientific evidence in favor of the usage of specific shunt technology for the treatment of hydrocephalus according to age, underlying pathology and other features of specific patients were discussed under the light of the current literature. Results: A total of 178 peer-reviewed papers were found. Out of them, only 21 matched our inclusion criteria and were finally selected. The papers were reviewed and described technology discussed below. A summary of the main types of shunts commercially available worldwide, including their respective working mechanism and construction was also included. Conclusion:Shunt technology has evolved during the last decades and continues to be intensively developed. Despite of the huge arsenal of different types of shunt systems currently available on the market, the treatment of hydrocephalus remains challenging. Investment in research, education and training, as well as prospective randomized multicentric controlled trials evaluating the role of specific valves in the treatment of individual group of hydrocephalic pediatric patients are urgently needed.


Molecules ◽  
2020 ◽  
Vol 25 (20) ◽  
pp. 4805
Author(s):  
Takashi Kuroiwa ◽  
Miki Ito ◽  
Yaeko Okuyama ◽  
Kanna Yamashita ◽  
Akihiko Kanazawa

Microchannel (MC) emulsification for the preparation of monodisperse oil-in-water (O/W) and water-in-oil-in-water (W/O/W) emulsions containing palm oil as the oil phase was investigated for application as basic material solid/semi-solid lipid microspheres for delivery carriers of nutrients and drugs. Emulsification was characterized by direct observation of droplet generation under various operation conditions, as such, the effects of type and concentration of emulsifiers, emulsification temperature, MC structure, and flow rate of to-be-dispersed phase on droplet generation via MC were investigated. Sodium caseinate (SC) was confirmed as the most suitable emulsifier among the examined emulsifiers, and monodisperse O/W and W/O/W emulsions stabilized by it were successfully obtained with 20 to 40 µm mean diameter (dm) using different types of MCs.


CNS Spectrums ◽  
1999 ◽  
Vol 4 (5) ◽  
pp. 32-34,47-48 ◽  
Author(s):  
Humberto Nicolini ◽  
Carlos Cruz ◽  
Beatriz Camarena ◽  
Francisco Páez ◽  
Juan Ramón De La Fuente

AbstractGenetic study holds potential for understanding the etiology of a number of serious psychiatric disorders. In the case of obsessive-compulsive disorder (OCD), many investigators agree that there is a strong genetic component to its development. In this article, we review the scientific evidence gleaned from different types of studies that has led to a better understanding of the nature of the inherited factors in OCD.


2020 ◽  
Vol 190 ◽  
pp. 110939 ◽  
Author(s):  
Bruna Barbon Paulo ◽  
Izabela Dutra Alvim ◽  
Gary Reineccius ◽  
Ana Silvia Prata

2014 ◽  
Vol 87 (4) ◽  
pp. 664-678 ◽  
Author(s):  
Leticia Saiz-Rodríguez ◽  
José María Bermejo-Muñoz ◽  
Andrés Rodríguez-Díaz ◽  
Alberto Fernández-Torres ◽  
Antonio Rubinos-Pérez

ABSTRACT Thermogravimetric analysis (TGA) and 14C techniques were compared for the determination of the biomass content of end-of-life tires (ELTs). Samples of different types (of ELTs) were prepared, and the biomass fraction of each sample was measured using the two methods (TGA and 14C). Six reference samples were also prepared with known quantities of natural rubber and stearic acid in order to establish the calibration curve necessary for the thermogravimetric analysis and to verify the accuracy of the results of the 14C analysis. The conclusions were that the 14C technique is the more valid, reliable, and precise method for determining the biomass content of end-of-life tires, since the results of the 14C tests of the reference samples coincided perfectly with the actual natural rubber and stearic acid content. On the other hand, the results of the thermogravimetric method differed considerably from the known natural rubber content of the reference samples as well as from the results of the 14C technique. This method is therefore not appropriate for use in determining the biomass content of end-of-life tires.


2019 ◽  
Vol 15 (1) ◽  
pp. 35
Author(s):  
Rety Setyawaty ◽  
Feriadi Feriadi ◽  
Dewanto Dewanto

Cream is a semi-solid emulsion dosage form of both water-in-oil (W/O) or oil in water (O/W) type containing one or more dissolved or dispersed ingredients in the corresponding base material (containing no less than 60% water). Cream is usually used as emollient or containing active pharmaceutical ingredients on the skin (Ansel, 2008). The advantage of cream are the application practicallity, water washeability, and the easiness to spread evenly. In this research, we formulated cream containing rhizome Galangal rhizome. According to Darmono (2008), Galangal rhizome has various properties such as antifungal and antibacterial activities. Galangal rhizome contains 1-asetoksikhavikol asetat (ACA). ACA is an antifungal. ACA has good solubility in 70% ethanol. We maserated Galangal rhizome (Alpinia galangal L.) to extract ACA from the simplicia. As for the cream base, we use hidrophilic base containing emulgators stearic acid and triethanolamine, with glycerin as humectant. During the optimization, we chose three formulas, formula 1 (10% stearic acid , 2% triethanolamin, 5% glycerin, and 0.01% vitamin E), formula 2 (15% stearic acid , 3% triethanolamin, 10% glycerin, and 0.05% vitamin E), and formula 3 (20% stearic acid, 4% triethanolamin, 7.5% glycerin, and 0.09% vitamin E). We used the bases to contain 10% of the extract. The results show that formula 1, formula 2, and formula 3 had typical smell of Galangal rhizome, brown color, and thick consistency. All formulas are homogenous. Formula 1 the best stability. We conclude that Galangal rhizome (Alpinia galanga L.) can be formulated in cream form with our formula 1 had the best stability among others.


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