Adherence to Antiretroviral Therapy among Patient Living with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (PLHA) Patients Visiting at Anti-retroviral Therapy Center in Pokhara

2020 ◽  
Vol 9 (1) ◽  
pp. 204-210
Author(s):  
Radhika Regmi ◽  
Sarita Karki ◽  
Saphalta Shrestha
Keyword(s):  
Art Therapy ◽  
Formal Education ◽  
Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Duration Of Treatment ◽  
Face To Face ◽  
Long Duration ◽  
The Status ◽  
Western Regional ◽  
Therapy Center

The main objective of this paper is to assess the status of adherence to Anti-Retroviral Therapy (ART) among patient living with HIV AIDS (PLHA) patients receiving ART therapy. A crosssectional descriptive design was used to collect data from 326 PLHA patients. Data were collected through face to face interview among the attended in ART clinic western regional hospital, Pokhara. Participants aged 18 years and above and patient receiving ART at least for 12 months or more were included in this study. The collected data entered in Epi-data and analysis was done using SPSS. The age group of the respondents was from 18 to 70 years with the mean age of 40.29±11.84 (SD). Out of 326 respondents 55.2% were male and 59.8% were married. Forty percent of the respondents had no formal education and most of the respondents (60.4%) were unemployed. Majority (86.5%) of respondents were taking ART since more than 2 years of duration. Majority of the respondents (92.9%) had >95% adherence with ART while 7.1% respondents had non- adherence. The majority of the PLHA patients have more than ninety five percent adherences to anti-retroviral therapy. Some of them have still nonadherence to ART and the reason they claimed were forgetfulness during travelling and too long duration of treatment. It is recommended to promote awareness program related to ART therapy and importance of its adherence to their family member and community people

scholarly journals To assess the adherence to antiretroviral therapy among HIV positive patients attending ART centres in Haryana and its effect on their quality of life

2021 ◽  
Vol 33 (2) ◽  
pp. 314-318
Author(s):  
Arundeep Singh ◽  
Anshu Mittal ◽  
Vishavdeep Kaur
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Art Therapy ◽  
Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Cross Sectional Study ◽  
Adherence Rate ◽  
Hiv Positive ◽  
Cross Sectional

Background: Acquired immune deficiency syndrome (AIDS) is now considered as a manageable chronic illness with the availability of ART. A high level of adherence (>95%) is required for antiretroviral therapy to be effective. It is a syndrome that builds a vacuum in a person affecting his/her quality of life (QOL) as a whole. Aim& Objective: The aim of our study was to determine adherence and its effect on their quality of life among HIV/AIDS patients attending FIART (Facility Integrated Anti-retroviral therapy) clinic. Materials and Methods: Using a cross-sectional study design,  257 HIV positive patients receiving antiretroviral therapy at Facility integrated anti-retroviral therapy centre Ambala Haryana. QOL of patients taking ART was assessed using WHO-QOL-BREF questionnaire.  Results: Of 257 participants, 88.3% were found to be adherent, adherent to ART therapy and ambulatory had better QOL (p < 0.05) than their counterparts from other socio-clinical strata. Mean scores of physical (70.89±7.384), psychological (47.37±9.174), social (51.97±11.119) & environmental domains (52.33±9.081), were having highest in patients those who were adherent (adherence rate >95%) to ART therapy. Conclusion: Adherence to antiretroviral therapy in Haryana India is suboptimal. Intensive adherence counselling should be provided to all patients before initiation of antiretroviral therapy and on every visit to FIART centre.

Arteriopathy in Children with Acquired Immune Deficiency Syndrome

1987 ◽  
Vol 7 (3) ◽  
pp. 261-275 ◽  
Author(s):  
Vijay Joshi ◽  
Bruce Pawel ◽  
Edward Connor ◽  
Leroy Sharer ◽  
James Oleske ◽  
...  
Keyword(s):  
Immune Deficiency ◽  
Immune Deficiency Syndrome ◽  
Acquired Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Acquired Immune Deficiency

Widespread use of herbal medicines by people living with human immunodeficiency virus and contamination of herbal medicines with antiretrovirals in Nigeria

2018 ◽  
Vol 30 (4) ◽  
pp. 371-377
Author(s):  
J Gini ◽  
A Amara ◽  
Sujan D Penchala ◽  
David J Back ◽  
L Else ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Human Immunodeficiency Virus ◽  
Herbal Medicine ◽  
Herbal Medicines ◽  
Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Medicine Use ◽  
Street Vendors ◽  
Hiv Therapy ◽  
Immunodeficiency Virus

Herbal medication use amongst people living with human immunodeficiency virus (PLWH) is widespread and understudied. This study aimed to evaluate the prevalence of herbal medicine use amongst PLWH and possible contamination with antiretrovirals (ARVs). Countrywide collection of herbal samples sold by street vendors in Nigeria for the following indications: human immunodeficiency virus (HIV), acquired immune deficiency syndrome, fever and general weakness. Samples were screened using a validated liquid chromatography-mass spectrometry/mass spectrometry method for the presence of the following ARVs: efavirenz, nevirapine, lopinavir, darunavir, ritonavir, atazanavir, emtricitabine, tenofovir and lamivudine. A survey was conducted among 742 PLWH attending four HIV clinics in Nigeria. Data were collected using a structured questionnaire and analysed using IBM SPSS statistics version 22.0 (IBM Corp., 2013, Armond, NY). Of the 138 herbal medicines sampled, three (2%) contained detectable levels of tenofovir, emtricitabine and/or lamivudine. Additionally, of the 742 PLWH surveyed, 310 (41.8%) reported herbal medicine use. Among the users, 191 (61.6%) started taking herbals after commencing HIV therapy while herbal medicine use preceded ARVs treatment in 119 (38.4%) PLWH. We found herbal use to be widespread among PLWH in Nigeria, with increasing use after commencing ARV. Three herbal preparations were also found to contain detectable levels of ARVs. This is a concern and should be studied widely across the region and countries where herbal medicine use is prevalent and poorly regulated.

scholarly journals Patients’ expectations on medicines information

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
A Sevikyan ◽  
I Kazaryan
Keyword(s):  
Storage Conditions ◽  
Community Pharmacies ◽  
Duration Of Treatment ◽  
Pharmacy Staff ◽  
Medicine Price ◽  
Expiry Date ◽  
Face To Face ◽  
Medicines Information ◽  
Number Of Patients ◽  
Effective Use

Abstract Background Medicines information is important for patients as it assists them in achieving more safe and effective use of pharmaceuticals. Many patients seek information from community pharmacies' staff. The objectives of this study were to identify specific topics of medicines information which patients expect to receive at community pharmacies. Methods Face-to-face interviews were conducted with 1059 visitors of community pharmacies in Armenia. Previously developed questionnaire was used for interviewing patients. Data were analysed with the SPSS statistical software. Results Most of participants acknowledged importance of receiving from community pharmacies' staff information on therapeutic indications of medicines (91.1%), dosage and method of administration (90.8%), the duration of treatment (86.3%), expiry date (85.7%), adverse reactions (85.0%), contraindications (84.6%), storage conditions (77.5%) and type of activity (76.0%). Importance of receiving information on some specific topics depends on patients' age. Participants' acknowledgement of information on interaction with other medicines, certain categories of users, and potential effects on the ability to drive is decreasing with patients' age increasing (p &lt; 0.001). The opposite trend was observed with attitude to receiving information on medicine price that was mostly valued by elderly patients (p = 0.046). The number of patients who trust the information provided was higher among those who more often received comprehensive responses from pharmacists and pharmacy assistants (p &lt; 0.001). Conclusions Receiving medicines information from the staff of community pharmacies is important for patients, and the majority of them trust to information received. Patients are mainly provided with comprehensive responses to their questions about medicines, and there was dependence between a frequency of receiving comprehensive responses and a level of patients' trust the information provided by pharmacy staff. Key messages Increasing patients’ awareness on their right to get medicines information can be beneficial. Comprehensive responses increase patients trust medicines information provided by pharmacists.

scholarly journals Wolman’s disease presenting with secondary hemophagocytic lymphohistiocytosis: a case report from Saudi Arabia and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fahad Alabbas ◽  
Ghaleb Elyamany ◽  
Talal Alanzi ◽  
Tahani Bin Ali ◽  
Fatma Albatniji ◽  
...  
Keyword(s):  
Hemophagocytic Lymphohistiocytosis ◽  
Metabolic Disorder ◽  
Clinical Signs ◽  
Failure To Thrive ◽  
Severe Infection ◽  
Signs And Symptoms ◽  
Immune Deficiency Syndrome ◽  
Autoimmune Disorder ◽  
Deficiency Syndrome ◽  
Homozygous Deletion

Abstract Background Hemophagocytic lymphohistiocytosis (HLH) is a rare and potentially fatal syndrome that is characterized by strong activation of the immune system from hyperinflammatory cytokines. Symptoms of HLH patients include fever, hepatosplenomegaly, cytopenia, and hyperferritinemia. Inherited HLH is classified as primary, whereas secondary HLH (sHLH) occurs when acquired from non-inherited reasons that include severe infection, immune deficiency syndrome, autoimmune disorder, neoplasm, and metabolic disorder. Wolman’s disease (WD) is a rare and fatal infantile metabolic disorder caused by lysosomal acid lipase deficiency, that exhibits similar clinical signs and symptoms as HLH. This paper reports the case of an infant diagnosed with WD and who presented with sHLH. Case presentation A 4-month-old infant presenting with hepatosplenomegaly, failure to thrive, and other abnormalities. WD diagnosis was confirmed by the presence of the LIPA gene homozygous deletion c.(428 + 1_967-1)_(*1_?)del. The infant also met the HLH-2004 diagnostic criteria. Conclusions Metabolic disorder such as WD should be investigated in infants fulfilling the HLH criteria to diagnose the underlying condition. More studies are needed to understand the link between WD and sHLH and to identify appropriate therapies.

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