scholarly journals Profile of Alcohol-Dependent Patients Admitted in De-addiction Ward of Tribhuvan University Teaching Hospital (TUTH), Kathmandu

2018 ◽  
Vol 6 (1) ◽  
pp. 38-43
Author(s):  
Saraswati Dhungana ◽  
Saroj Prasad Ojha ◽  
Manisha Chapagain ◽  
Pratikchya Talachan ◽  
Sagun Ballav Pant ◽  
...  

Introduction: Alcohol dependence is a global problem worldwide and the global burden of disease study published in 2010 concluded alcohol use to be the third leading risk factor for death and disability. This study was conducted to find out the diagnostic profile, socio- cultural determinants, motivation level and other related variables in patients diagnosed as alcohol dependence in hospital admitted patients.Material and Method: This was a cross- sectional study carried out in patients diagnosed as alcohol dependence and admitted in the deaddiction ward of Tribhuvan University Teaching Hospital over a period of eight months. SPSS version 18 was used for the statistical analysis of the data obtained.Results: A total of 86 patients were admitted during the period of 8 months. Among those, 48% were admitted with the diagnosis of alcohol dependence- complicated withdrawal while remaining 52% were admitted with alcohol dependence- uncomplicated withdrawal. Assessment of motivation revealed that majority of the patients i.e.43% were in precontemplation phase, 27.9% were in the contemplation phase, 9.3% were in preparation phase, and 19.8% were ready to take action for remaining abstinent. Sociodemographic variables were not statistically significant except for family type where more than 70% of patients with complicated withdrawal belonged to nuclear family when compared to uncomplicated withdrawal.Conclusion: In this study, we assessed the overall profile of patients admitted with alcohol dependence syndrome in a tertiary care hospital so that this data can be used for better management of our patients.J Psychiatrists’ Association of Nepal Vol .6(1), 2017, p.38-43

2021 ◽  
Vol 19 (1) ◽  
pp. 19-25
Author(s):  
Pravin Prasad ◽  
Anish Mudvari ◽  
Rakesh Ghimire ◽  
Naresh Karki ◽  
Dipendra Yadav ◽  
...  

Background: Drug promotional literatures can often be misleading and have biased information and can contribute to irrational use of medicines. Thus, it is necessary that prescribers critically analyze the drug promotional literatures presented to them. This study attempts to understand if the prescribers at Tribhuvan University Teaching Hospital are aware about the necessary information that should be present in a drug promotional literature.Methods: A descriptive cross-sectional study was conducted over six months in which prescribers at Tribhuvan University Teaching Hospital were provided with the self-administered questionnaire and were requested to submit the filled in questionnaire. Prescribers presently working at Tribhuvan University Teaching Hospital, attending out patient department services and had received drug promotional literatures within last six months were included in this study. Results: During the study, 163 of the received questionnaires met the inclusion criteria and were utilized for analysis. Advertisement, reminder items and others type of drug promotional literatures were commonly received by prescribers included in our study. Higher proportion of faculties (35.29%) preferred reprint type of drug promotional literatures. Most of the participants (47.85%) searched for 5-8 WHO-Ethical Criteria for Medicinal Drug Promotion criteria when referring a drug promotional literature. It was seen that 42.94% of prescribers realised that at least two out of four types of information related to negative attribute of the promoted medicines were missing.Conclusions: The prescribers with least duration of clinical exposure are more likely to always prescribe the medicines promoted to them. Prescribers were more confident on claims made in drug promotional literatures if they were supported using scientific evidences.Keywords: Drug promotional literatures; prescriber perception;WHO-ECMDP


2015 ◽  
Vol 12 (3) ◽  
pp. 202-206 ◽  
Author(s):  
DR Kafle ◽  
KK Oli

Background Epilepsy is a common and diverse disorder with many different causes. Outcomes are varied with 60—70% of newly diagnosed people rapidly entering remission after starting treatment and 20—30% developing a drug-resistant epilepsy with consequent clinical and psychosocial distress. About one third of patients with a first unprovoked seizure will have further seizures within five years, and about three quarters of those with two or three unprovoked seizures have further seizures within four years.Objective The aim of the study was to find out those factors which were associated with recurrence of seizure in Nepalese population.Method It is a Descriptive Cross-sectional study which was conducted in Tribhuvan University Teaching Hospital from January 2013 to January 2014.Result A total of 150 patients participated in the study. Neuroimaging was normal in 65(43.3%) patients. 48(32%) patients had neurocystercosis in their brain imaging, neuroinfection in 12(8%) of cases, cerebral infarction in 12(8%), Cerebral atrophy in 5(3.3%) patients, brain tumor in 4(2.7%), Mesial temporal sclerosis in 2(1.3%), tuberous sclerosis in 1(0.7%) and hypoxic brain injury in 1 (0.7%) patient. 14(9.3%) patients reported having a family history of epilepsy in first degree relative. There was statistically significant association between higher number of seizures before starting medication and increased frequency of seizure after starting medication (p<0.001).Conclusion Most of the patients with recurrent seizure had identifiable cause. Neurocysticercosis was the most common cause. Higher number of seizure before starting medication was associated with increased frequency of seizure after starting medication.Kathmandu University Medical Journal Vol.12(3) 2014; 202-206


2013 ◽  
Vol 9 (2) ◽  
pp. 9-14
Author(s):  
S Fatima ◽  
NK Afridi ◽  
S Khan

Introduction: Globally, around 34 million people are living with HIV in 2010, and 35% of the pregnant  women are tested for HIV in the low and middle income countries. HIV infection in pregnancy has  become a complication of pregnancy in some developing countries. This has major implications for  the management of pregnancy and birth. With an estimated one and a half million HIV-positive women  becoming pregnant each year, almost 600,000 children will be infected by mother-to-child transmission  annually. Methodology: A cross sectional study was conducted from October – December 2011 in the Department  of Obstetrics and Gynecology, Khyber Teaching Hospital, Peshawar. It is a tertiary care hospital located  in Peshawar. A sample of 200 pregnant females was used to accomplish the study. The targeted study  population was all antenatal attendees who were visiting the hospital within the current pregnancy. A pre-  coded, pre- tested structured questionnaire was used to gather information on the study variables. The  questionnaire included variables related socio-demographics e.g., age, education status, occupation,  residence. It also included the gestational age and gravidity of the pregnant females. Results: A total of 200 pregnant females attending the antenatal clinic participated in the study. The  age range of the respondents was 17 to 45 years. Age range 17-25 years accounted for the highest  percentage (52%). Around 70% of the respondents had no formal schooling while only 18% had got  secondary education. Ninety – seven percent of the females were housewives while only 3% were  employed. Out of the total respondents (200) only 86 (43%) have heard of HIV while 114 (57%)  respondents have not heard of HIV. Conclusion: The study concluded that only 43% of the pregnant females have heard of HIV. Although  this is not promising still there is room for improvement. Health education targeting pregnant females is  essential. SAARC Journal of Tuberculosis, Lung Diseases & HIV/AIDS; 2012; IX(2) 9-14 DOI: http://dx.doi.org/10.3126/saarctb.v9i2.7972


2020 ◽  
Vol 59 (233) ◽  
Author(s):  
Gita Khakurel ◽  
Chandrima Karki ◽  
Sanat Chalise

Introduction: The function of the thyroid gland is altered during pregnancy. Thyroid disorders during pregnancy are associated with serious maternal and fetal outcomes. Universal screening for thyroid disorders is recommended in the first trimester of pregnancy. This study aims to determine the prevalence of thyroid disorder during pregnancy in women attending a tertiary care hospital. Methods: A descriptive cross-sectional study was conducted in the Department of Obstetrics and Gynaecology of Kathmandu Medical College and Teaching Hospital from March 2020 to August 2020 after obtaining ethical approval from the Institutional Review committee with reference number 20032020. The pregnant women >18 years of age, irrespective of their gestational age and gravida status, were included in the study by convenience sampling method. The participants were screened by estimation of thyroid function test. Data were collected, and statistical analysis was done in Statistical Packages for Social Services version 20.0. Results: A total of 329 pregnant women were included in this study. The prevalence of thyroid disorders in the present study is 24.62 %. The most common thyroid disorder observed was subclinical hypothyroidism comprising 65 (19.75 %) cases followed by overt hypothyroidism 8 (2.43%) cases. Conclusions: There is a high prevalence of thyroid disorders during pregnancy in our settings. Timely screening of pregnant women helps in the early diagnosis and management of complications related to thyroid disorders.    


2021 ◽  
Vol 11 (2) ◽  
pp. 102-106
Author(s):  
Akhtar Ali Khan ◽  
Anwar Ali ◽  
Hussan Zeb ◽  
Bakht Rahman ◽  
Ijaz Arif ◽  
...  

Background: This research aimed to assess the current care management processes for COVID-19 and determine patient outcomes. Methods: An analytical cross-sectional study was conducted at Saidu group of teaching hospital, a tertiary care hospital with more than a thousand-bed capacity. The target population was all patients admitted to the corona isolation ward and the hospital's critical unit. All the patients admitted through the emergency and inpatient department with Positive PCR, and respiratory symptoms were included in the study. Results: In total, data of 151 patients were collected. Of these, 90 (59.6%) were male and 61 (40.4%) were female with a mean age of 59.17±13.79. The most common presenting symptoms were difficulty in breathing (n=147, 97.4%) and dry cough (n=104, 68.9%), followed by aches and pain (n=71, 47%) and fever (n=60, 39.7%). Most of the patients had an underlying health condition (n=96, 63.6%). The most common underlying conditions were hypertension (n=65, 43%) and diabetes (n=56, 37.1%). The mean time for the hospital stay was 11.68±15.31. About 64% of the patients recovered with the treatment and care protocols (n=97, 64.2%), while the remaining (n=54, 35.8%) died. Conclusion: This study provides an overview of the clinical presentation and treatment protocol for COVID-19. Most of the patients received supportive treatment comprising of antivirals, steroids, and oxygen therapy. However, the mortality rate was low compared to other hospitals across the country.


Author(s):  
PRINCY EASOW ◽  
OLISHA DELVITA MENDONCA ◽  
DHAVAL SIDHDHAPURIA ◽  
JITENDRA VAGHASIYA

Objectives: This study was conducted to identify and report the adverse drug reactions (ADRs) which are occurring in pediatric and medicine departments in a tertiary care hospital at Vadodara. Methods: A cross-sectional study was conducted for 6 months in-patient at a tertiary care teaching hospital. We enrolled the patients based on inclusion criteria and data was analyzed with the help of MS excel 7 and Graph pad Prism. Further, the assessments of type, severity, and preventability of reported ADRs were done using Wills and Brown classification, modified Schumock and Thornton severity scale, modified Hartwig and Siegel preventability scale. Results: Data were collected from a total of two hundred patients of which twenty-six (13%) patients were affected with ADRs. Among twenty-six patients, females (64%) were more affected with ADRs when compared to males (36%). According to the department, most ADRs were observed in the medicine ward than in the pediatric. The highest number of ADRs was associated with antibiotics (46.1%). Based on the type of ADRs, Type B ADRs (77%) were more observed followed by Type A (7%) and Type C (8%). Conclusions: The information obtained from our study will help clinical pharmacists and healthcare professionals to take precautions in the future and adopt certain measures for preventing the ADRs and hence help in promoting safer and rational drug use in institutions and improving the quality of patient care.


2021 ◽  
Vol 59 (234) ◽  
Author(s):  
Kripa Dongol ◽  
Yogesh Neupane ◽  
Heempali Das Dutta ◽  
Bigyan Raj Gyawali ◽  
Bijaya Kharel

Introduction: Foreign body aspiration is a common problem in children with signifi cant mortality and morbidity. This study aims to determine the prevalence of foreign body aspiration in children in a tertiary care hospital of Nepal. Methods: A descriptive cross-sectional study was conducted at Tribhuvan University Teaching Hospital from April 2010 to March 2016 after obtaining ethical approval from Institutional Review Committee (Reference number- 08(6-11)E277/78). All children of age up to 15 years with suspected foreign body aspiration were included. The data was collected from the medical record section and entered in Microsoft Excel. The descriptive statistical analysis was performed. Results: A total of 26,294 patients were included in the study. The prevalence of foreign body aspiration in children was found to be 98 (0.37%). On rigid bronchoscopy, 82 patients (83.6%) were confirmed to have a foreign body in the airway. The peak incidence of foreign body aspiration was seen in patients of age group one to two years. The commonest foreign body in the airway was a peanut. Conclusions: The prevalence of foreign body aspiration in children was low, which is similar to other studies. Foreign body aspiration may lead to dreadful complications. Therefore, both the clinicians and the public need to be cautious about it.


2019 ◽  
Vol 57 (219) ◽  
Author(s):  
Anu Kushwaha ◽  
Anuj Raj Kadel

Introduction: Family medicine is a relatively overlooked specialty in Nepalese medical education. It is unclear how many interns are actually interested in Family medicine as a career and how many non-medical individuals are aware of its existence. The aim of this study is to assess information, expectation and perception among interns regarding family medicine and its choice as a career. Methods: This is a descriptive-cross sectional study carried out in Kathmandu Medical College Teaching Hospital from July 2018 to December 2018. Whole sampling was done. All interns of Kathmandu Medical College Teaching Hospital posted in different departments during the time period was the inclusion criteria. Chronic absentees was the exclusion criteria. Factor like age, sex, their residency of choice, and whether they consider family medicine as a potential career were considered. Data was entered in with Statistical Package for Social Services version 16 and necessary calculations were done. Results: Thirty three interns preferred internal medicine as their career of choice, 20 preferred surgery while only three preferred in family medicine. Eighty eight interns, including the three who had family medicine as their career of choice, said that they could consider family medicine as a potential career. Eighty eight out of the 100 interns in the study mentioned that their family had knowledge that a specialty called family medicine existed. Conclusions: Despite being the career of choice of only a few, majority considered family medicine as a potential career for them. And the knowledge about existence of family medicine was high among families of interns.


2021 ◽  
Vol 9 (1) ◽  
pp. 16-24
Author(s):  
Neeta Shakya Malla ◽  
Supri Raj Shrestha ◽  
Deepa Shah

Background and Objectives: In Nepal, person aged 60 years and above is considered elderly. The population of Nepal is approximately 30 million, and people aged 60 years and above makes about one tenth of the total population. This study aims to report the main complaints and prevalence of otorhinolaryngological diseases in patients aged 60 years and above, who visited outpatient otolaryngology department of Manmohan Memorial College and Teaching Hospital, Kathmandu, Nepal during study period. Material and Methods: It is a prospective descriptive cross-sectional study done in Manmohan Memorial College and Teaching Hospital, Kathmandu, Nepal for the duration of a year. All patients aged 60 years and above attending to Ear, Nose and throat (ENT) Outpatient Department were included in the study. The information including demographic data, ENT Complaints and physical examination were noted. Analysis of data was done and report was prepared. Results: Total of six hundred and ninety three patients were enrolled over the period of one year for the study. Number of Male and female patients in the study were almost equal. The otological problems had the highest prevalence constituting 51.7% of the study population. More than Twenty eight (28.3 %) percent had oral and oropharyngeal pathologies. Nasal complaints constituted 10.8% of the study population and 9.2% had pathologies related to neck and others. Conclusion: Hearing loss is the most common diagnosis among all the otological pathologies and epistaxis the most common nasal problem. Head and Neck malignancy is also increasing among the geriatric population.


2021 ◽  
Vol 59 (240) ◽  
Author(s):  
Mukti Acharya

Introduction: Alcohol dependence syndrome is an important and major public health issue seen in our community and health center. It is mostly associated with different mental health problems and psychiatric co-morbidities. This study aims to find out the prevalence of depression among alcohol dependence syndrome in a tertiary care hospital. Methods: A descriptive cross-sectional study was conducted over one year from April 15, 2020, to February 15, 2021 at a tertiary care hospital. The ethical approval was obtained from the Institutional Review Committee of Nobel Medical College (reference number: 409/2020). Convenience sampling method was used. The patients admitted for alcohol use and related problems in the Psychiatry Department, Nobel Medical College Teaching Hospital, Biratnagar were included. Data entry was done using Microsoft Excel and statistical analysis was done by using Statistical Packages of Social Sciences Version 16.0. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage. Results: The prevalence of depression in patients with Alcohol Dependence Syndrome was 17 (16.3%) (95% Confidence Interval= 9.20-23.39) . The patients suffering from depressive disorder male and female were 16 (94.1%) and 1 (5.8%) respectively. The participants with Alcohol Dependence Syndrome with no other comorbid psychiatric disorders were found to be 60 (57.7%). Conclusions: Psychiatric comorbidity was found to be common in alcohol dependent people among which depression was found to be most common.


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