scholarly journals Lithium content in the population of the Aktobe region of the Republic of Kazakhstan and the relationship with mental illness: a cross-sectional study

Author(s):  
G. A. Batyrova ◽  
G. A. Umarova ◽  
E. A. Umarov ◽  
P. Z. Aitmaganbet ◽  
Z. S. Tlegenova ◽  
...  

The article presents data on the study of the content of lithium in the hair of the adult population of the Aktobe region of the Republic of Kazakhstan and the relationship with mental illness. The aim of the study is to assess the content of lithium in the biosubstrates of the adult population and its relationship with the morbidity of the population of the Aktobe region.Materials and methods: A one-stage cross-sectional study was carried out on the territory of the Aktobe region of the Republic of Kazakhstan. The study included 340 residents aged 18-60 years permanently residing in the study area using the method of simple random sampling. The lithium content in hair was determined by inductively coupled plasma mass spectrometry on a NexION 300D spectrometer (PerkinElmer Inc., USA) equipped with an ESI SC-2 DX4 sampler (Elemental Scientific Inc., USA). The morbidity rates were studied according to the ICD-10 classes per 100 thousand population. To assess the relationship between the Li content in the hair and the morbidity rates, the Spearman rank correlation coefficient was calculated.Results: According to the results of the study, significant deviations from the reference values were observed for the lithium content in the Aktobe region. There is an excess of lithium for 80.59% (CI: 76.38; 84.79) of the subjects, the norm is 19.41% (CI: 15.21; 23.62). Excess lithium is more common in men than in women (χ2  =11.07 df=1; p=0.001). Considering the districts of the Aktobe region, the highest content of Li (Me (q25-q75)) was found in the Aitekebi district (0.084 (0.022 -0.134)) mcg/g, in the Kobda district 0.069 (0.060- 0.076) mcg/g, in the Mugalzhar district 0.046 (0.019-0.066) mcg/g, in the Oiyl district 0.044 (0.021-0.0762) mcg/g, in the Alga district 0.040 (0.024-0.090) mcg/g. Spearman’s correlation rank analysis showed a weak positive association of Li content with age (r=0.20, p =0.0001), no association with body mass index was found (r=0.10, p =0.06). The correlation analysis established a direct inverse average relationship between the content of Li and morbidity in the class of diseases “Mental disorders and behavioral disorders” (r=-0.62; p= 0.044).Conclusions: The high prevalence of excess lithium content in the hair of the population and its relationship with mental illness requires further research. The study of the bioelement status of the population can serve as an indicator of environmental pollution, and also aims at monitoring the ecological situation in the region.

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Deepak Gowda Sadashivappa Pateel ◽  
Shilpa Gunjal ◽  
Liew Fong Fong ◽  
Nur Sulwana Mohd Hanapi

Background. Saliva, as a complex biofluid, plays a pivotal role in maintaining oral health and tooth integrity. There has been inconsistent data available on the relationship between salivary parameters and oral health. This study aims to investigate the association between salivary statherin, acidic proline-rich proteins (aPRP), and calcium with oral hygiene status. Methods. One hundred and eighty-eight healthy subjects aged between 18 and 50 years with varying oral hygiene status who gave consent to participate were included in this cross-sectional study. The subjects were recruited from primary oral health care of MAHSA University. Oral hygiene of all the participants was measured using Oral Hygiene Index–Simplified (OHI-S). Stimulated saliva collected using paraffin wax was analyzed for salivary statherin, aPRP, and calcium. The relationship between salivary statherin, aPRP, and calcium levels with OHI-S was assessed using Spearman’s Rank correlation coefficient; the strength of relationship was assessed by multiple linear regression analysis. Results. The study found a weak positive correlation (r = 0.179, p  = 0.014) between salivary statherin and OHI-S; weak negative correlation (r = −0.187, p  = 0.010) between salivary aPRP and OHI-S; and moderate negative correlation between salivary statherin and salivary aPRP levels (r = −0.50, p  < 0.001) which were statistically significant. Conclusion. Poor oral hygiene is associated with increased statherin and reduced aPRP levels in saliva. Thus, these salivary components may have a role in predicting oral hygiene status.


2020 ◽  
Vol 2020 ◽  
pp. 1-9 ◽  
Author(s):  
Karima Mohtadi ◽  
Rajaa Msaad ◽  
Najwa Benalioua ◽  
Ali Jafri ◽  
Hasnaa Meftah ◽  
...  

Several studies had revealed that following the Mediterranean diet (MD) contributes to beneficial health status and a decreased risk of many chronic diseases. The aim of our study was to assess adherence to MD in Casablanca City and to identify the relationship between MD adherence and sociodemographic and lifestyle parameters. This cross-sectional study concerned 719 subjects with complete dietary data. Data collection was performed using a questionnaire including sociodemographic and lifestyle factors. The dietary intake was assessed with the use of a food-frequency questionnaire. The compliance with MD was evaluated with a simplified MD score. Our study showed that high adherence to the MD was characterized by high intakes of vegetables, fruits, pulses, fish, cereals, olive oil, and low meat and dairy consumption according to the Simplified MD score. As regard to the multivariate logistic, being a man, being married, persons with a level of education >6 years, luxurious housing, and consumption of alcohol were associated with a higher adherence to MD, while, the overweight was negatively associated with a higher adherence to MD. Maintaining the traditional MD pattern is crucial for public health; in this way, more research is needed in this area in order to precisely measure these associations.


2017 ◽  
Vol 54 (3) ◽  
pp. 423-441 ◽  
Author(s):  
Yaara Zisman-Ilani ◽  
Ilanit Hasson-Ohayon ◽  
Itamar Levy-Frank ◽  
Rivka Tuval-Mashiach ◽  
David Roe

The current cross-sectional study investigated and compared the associations between insight, self-stigma, and family burden among Jewish and Arab mothers of an adult son or daughter with serious mental illness (SMI) in Israel. A total of 162 Israeli mothers of a person with SMI participated in the study; 95 were Jewish (58.6%), and 67 were Arab (41.4%). Insight, self-stigma, and family burden scales were administered. Jewish mothers reported higher levels of insight into their son’s or daughter’s illness and reported greater family burden compared to Arab mothers. No significant differences in self-stigma scores were found between Jewish and Arab mothers. The pattern of associations between insight, self-stigma, and burden differed between Jewish and Arab mothers. Self-stigma was found to mediate the relationship between insight and burden among Jewish mothers but not among Arab mothers. Ethno-national affiliation should be taken into consideration regarding how family members conceptualize and experience mental illness, as this might affect care.


2017 ◽  
Vol 33 (4) ◽  
pp. 167
Author(s):  
Nine Luthansa ◽  
Dibyo Pramono

Body mass index and incidence of diabetes mellitus in adult population in Indonesia: analysis of IFLS data 5PurposeThis study aimed to determine the relationship between BMI with DM incidence in the adult population in Indonesia.MethodsThis cross sectional study was conducted using the 5th Indonesian Family Life Survey (IFLS5) data which is a collaboration of the RAND corporation and Survey Meter. Chi square and logistic regression tests were used to analyze the relationship between BMI and DM incidence. BMI was obtained through measurement of body weight and height in respondents aged > 18 years. Information on the incidence of DM was obtained from interviews with respondents.ResultsThere were 22,647 subjects who met the study criteria. The proportion of DM in this study was 2.89%. People with obese BMI had a higher risk of developing DM than people with underweight BMI (OR = 3.15; 95% CI = 2.05- 4.82). After adjusting for gender, age, and education variables, the risk remained significant (OR = 3.29; 95% CI = 2.14-5.065).ConclusionBody mass index is associated with the incidence of diabetes mellitus, in which people with excessive BMI or obese have a greater risk of developing DM than people with underweight BMI.


Author(s):  
Subhashri Jahagirdar ◽  
Laxmikant Lokare ◽  
D D Bant ◽  
Geeta V Bathija ◽  
Maneesha Godbole ◽  
...  

2018 ◽  
Author(s):  
Andysah Putera Utama Siahaan ◽  
Rusiadi

Waste is a problem faced in the worldwide. One strategic to minimizing the volume of waste is waste management at school or campus. The purpose of this cross- sectional study was to examine the relationship between knowledge, attitude and behavioral intention of waste management among college student in Diploma Nursing and Midwife Pematangsiantar. The participants were composed of 228 nursing and midwife student, and they were selected by stratified random sampling from Diploma of Nursing and Midwife, Pematangsiantar. The data was collected by using questionnaires consisting of information, knowledge, attitude and behavioral intention. Spearman Rank Correlation was used to identify relationships between, knowledge, attitude and behavioral intention. The study found that the majority of participants (88,2%) with the average age was 20,27 years old. The major study was nursing (39,5 %) with the VI semester. Knowledge and attitude were related to behavioral intention (r=0.550, p&lt;0,01; r=0.183, p&lt;0,06) respectively. Students reported good knowledge, positive attitude, and high behavioral intention. The study suggested that student should maintain their behavioral intention towards waste management. Also, the institution should provide more information on campus about how to recycle waste into useful.


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