scholarly journals PLASMID-INDUCED ANTIBIOTIC RESISTANCE AMONG PATHOGENS OF CHRONIC PYELONEPHRITIS: PREVALENCE OF GENES AND MAJOR RISK FACTORS

2016 ◽  
pp. 52-55
Author(s):  
О. Chub ◽  
O. Bilchenko
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Resistance Genes ◽  
Chronic Kidney Disease Stage ◽  
Resistance Mechanisms ◽  
Chronic Pyelonephritis ◽  
Disease Stage ◽  
Patient Treatment ◽  
Cross Sectional

The aim of the study is to determine the prevalence of plasmid-mediated resistance genes among uro- pathogens from hospitalized patients with chronic pyelonephritis. Methods. A cross-sectional study of 105patients with chronic pyelonephritis and different stage of chronic kidney disease, was carried. Screening for the presence ofplasmid-mediated genes was performed by polymerase chain reaction. Determining the risk factors was performed by analysis of prevalence Odd-ratio. Results. The prevalence of plasmid-mediated resistance mechanisms among uropathogens is 36.7%, mainly due to extended-spectrum p-lactamase (25%). The main factors related with appearance of plasmid-mediated resistance genes were age range above 55 years (OR 3.05), hypertension (OR 2.57), Chronic Kidney Disease stage ІІІ (OR 2,03) and V (OR 1,1), in-patient treatment history (OR 2.02), duration of CP more than 10 years (OR 1,97), history of using antibiotics last year (OR 1,41). Conclusion. Isolation and detection of plasmid-mediated resistance mechanisms among urinary strains are essential for the selection of the most effective antibiotic for the empiric treatment.

scholarly journals Frailty and sarcopenia in elderly non-dialysis patients with chronic kidney disease stage 3-5: a cross sectional study

2020 ◽  
Author(s):  
Jing Chang ◽  
Yan-Fei Wang ◽  
Wen-Wen Hou ◽  
Yan-Chun Li ◽  
Zhuo-Ran Qi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Chronic Kidney Disease Stage ◽  
Cross Sectional Study ◽  
Disease Stage ◽  
Sectional Study ◽  
Dialysis Patients ◽  
Cross Sectional ◽  
Independent Risk Factors

Abstract Background With the aging of the population, chronic kidney disease (CKD) and sarcopenia are the common diseases among the elderly. Non-dialysis patients with CKD account for a relatively high proportion, and the analysis of their general clinical characteristics has been more familiar. However, the study of sarcopenia in non-dialysis with CKD is not enough. Methods This is a cross sectional study. Non-dialysis patients with CKD stage 3–5 were continuously selected. Patients were divided into 3 groups based on the Fried scale, Non-frail group, Pre-frail group and Frail group. At the same time, muscle mass of the hospitalized patients was measured by dual-energy X-ray absorptiometry (DXA), and according to the test results, they were divided into sarcopenia and non-sarcopenia group. Baseline data and the measurement of the sarcopenia of the two groups were analyzed. Results A total of 102 elderly patients with chronic kidney disease stage 3–5 were continuously enrolled. There were 21 patients (20.6%) categorized as sarcopenia, 81 patients (79.4%) categorized as non-sarcopenia according to the measurement results of DXA. Frailty was assessed by the criteria of frailty phenotype, there were 13 patients of sarcopenia in the frail group, 6 patients of sarcopenia in the pre-frail group, and 2 patients of sarcopenia in the non-frail group, accounting for 31.7%, 20.0%, 6.5%, respectively. Moreover, the analysis of the related risk factors of sarcopenia showed that body mass index (BMI)༜23 kg/m2(OR = 3.82, 95%CI 1.33–10.97, P = 0.013), MNA-SF ≤ 11(OR = 3.97, 95%CI 1.08–14.58, P = 0.038) were the independent risk factors for sarcopenia in non-dialysis patients with chronic kidney disease stage 3–5. Conclusions The prevalence of sarcopenia in elderly non-dialysis patients with chronic kidney disease stage 3–5 was high, and sarcopenia was common in the frail patients. BMI༜23 kg/m2 and MNA-SF ≤ 11were the independent risk factors for sarcopenia in non-dialysis patients with chronic kidney disease stage 3–5.

scholarly journals Five-Year Incidence of Chronic Kidney Disease (Stage 3-5) and Associated Risk Factors in a Spanish Cohort: The MADIABETES Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0122030 ◽  
Author(s):  
Miguel A. Salinero-Fort ◽  
Francisco J. San Andrés-Rebollo ◽  
Carmen de Burgos-Lunar ◽  
Paloma Gómez-Campelo ◽  
Rosa M. Chico-Moraleja ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Chronic Kidney Disease Stage ◽  
Disease Stage ◽  
Associated Risk Factors ◽  
Spanish Cohort

scholarly journals Analysof Reticulocyte Hemoglobin Equivalent Levels in Patients with Chronic Kidney Disease Stage IV and V

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Agri Febria Sari ◽  
Rikarni Rikarni ◽  
Deswita Sari
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Iron Status ◽  
Chronic Kidney Disease Stage ◽  
Stage Iv ◽  
Disease Stage ◽  
Cross Sectional ◽  
Iron Storage ◽  
Laboratory Installation ◽  
Ckd Stage

Reticulocyte hemoglobin equivalent (RET-He) represents hemoglobin content in reticulocyte. Reticulocyte hemoglobin equivalent test can be used to asses iron status of chronic kidney disease (CKD). Iron deficiency happens in 40% CKD and could lead to anemia manifestation. Level of RET-He gives real-time assesment of iron availability for hemoglobin production and the level will getting lower when iron storage for erythropoiesis decreasing. Reticulocyte hemoglobin equivalent is more stabil than feritin and transferin saturation in assessing iron status. Aim of this study is to determine RET-He level in patients with CKD stage IV and V. This study is  a cross sectional descripstive study. Subjects were 96 CKD stage IV and V patients that met inclusion and exclusion criterias. Subjects conducted blood tests at Central Laboratory Installation Dr. M. Djamil Hospital Padang from July to September 2020. Examination of RET-He level was analyzed by Sysmex XN-1000 flowcytometry fluorescense method. Data was presented in frequency distribution table. The RET-He level below cutoff (<29,2 pg) indicates the need for iron suplementation therapy for CKD stage IV and V patients. Samples with RET-He level below cutoff were 48 (50%) and 48 (50%) were above cutoff.

scholarly journals Distribution of Pruritus and Its Association With Serum Parathormone Level in Chronic Kidney Disease (Stage-5) Patients On Maintenance Hemodialysis

2020 ◽  
Vol 28 (1) ◽  
pp. 54-59
Author(s):  
Rafiqul Hasan ◽  
Md Nizamuddin Chowdhury ◽  
Md Nazrul Islam ◽  
Parvez Iftekher Ahmed ◽  
ASM Tanim Anwar ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Chronic Kidney Disease Stage ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Normal Serum ◽  
Disease Stage ◽  
Maintenance Hemodialysis ◽  
Cross Sectional ◽  
Maintenance Haemodialysis

Background: Pruritus is a common manifestation in patients on hemodialysis. The aim of this study is to determine the distribution of pruritus and evaluate the association between pruritus and serum parathormone levels in chronic kidney disease patients on maintenance haemodialysis. Methods:This analytic, descriptive, cross-sectional study was performed over 191 patients of maintenance haemodialysis in 2014. Information related to the patients including age, gender, residence, pruritus was extracted from questionnaires. Serum levels of intact parathormone were measured & data were analyzed. Results: 68% of the patients had pruritus. The Mean ± SD of serum parathormone was 53.25±7.96 pg/ml in patients with pruritus and 81.91±9.34 pg/ml in patients without pruritus. Our study showed that most patients with pruritus had normal serum parathormone levels and no significant association was found between pruritus and serum parathormone levels. Conclusion: serum parathormone level may not play a role in uraemic pruritus in these patients. J Dhaka Medical College, Vol. 28, No.1, April, 2019, Page 54-59

scholarly journals Secreted Klotho and FGF23 in chronic kidney disease Stage 1 to 5: a sequence suggested from a cross-sectional study

2012 ◽  
Vol 28 (2) ◽  
pp. 352-359 ◽  
Author(s):  
Ivana Pavik ◽  
Philippe Jaeger ◽  
Lena Ebner ◽  
Carsten A. Wagner ◽  
Katja Petzold ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Chronic Kidney Disease Stage ◽  
Cross Sectional Study ◽  
Disease Stage ◽  
Sectional Study ◽  
Cross Sectional ◽  
Stage 1

scholarly journals Identifying risk factors for chronic kidney disease stage 3 in adults with acquired solitary kidney from unilateral nephrectomy: a retrospective cohort study

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Wen-Jun Zhang ◽  
Zi-Yi Wang ◽  
Wei-Xing Zhou ◽  
Ning-Qiang Yang ◽  
Ya Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Chronic Kidney Disease Stage ◽  
Adult Patients ◽  
Unilateral Nephrectomy ◽  
Disease Stage ◽  
Ckd Stage ◽  
Renal Tuberculosis

Abstract Background We aimed to examine the risk factors for chronic kidney disease (CKD) stage 3 among adults with ASK from unilateral nephrectomy. Methods We retrospectively collected data from adult patients with ASK between January, 2009 and January, 2019, identified from a tertiary hospital in China. The clinical data were compared between patients who developed CKD stage 3 and those who did not develop CKD stage 3 during follow-up. Results In total, 172 patients with ASK (110 men; median 58.0 years) were enrolled, with a median follow-up duration of 5.0 years. During follow-up, 91 (52.9%) and 24 (14.0%) patients developed CKD stage 3 and end-stage renal disease, respectively. Multiple regression analyses showed that age (odds ratio [OR] 1.076, 95% confidence interval [CI] 1.039–1.115, p < 0.001), diabetes (OR 4.401, 95% CI 1.693–11.44, p = 0.002), hyperuricemia (OR 2.733, 95% CI 1.104–6.764, p = 0.03), a history of cardiovascular disease (CVD) (OR 5.583, 95% CI 1.884–18.068, p = 0.002), and ASK due to renal tuberculosis (OR 8.816, 95% CI 2.92–26.62, p < 0.001) were independent risk factors for developing CKD stage 3 among patients with ASK. Conclusions Regular follow-up of renal function is needed among adult patients with ASK. Optimal management of diabetes, hyperuricemia, and CVD may reduce their risk of CKD stage 3, especially among those that undergo unilateral nephrectomy for renal tuberculosis.

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