scholarly journals Five-Year Incidence of Chronic Kidney Disease (Stage 3-5) and Associated Risk Factors in a Spanish Cohort: The MADIABETES Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0122030 ◽  
Author(s):  
Miguel A. Salinero-Fort ◽  
Francisco J. San Andrés-Rebollo ◽  
Carmen de Burgos-Lunar ◽  
Paloma Gómez-Campelo ◽  
Rosa M. Chico-Moraleja ◽  
...  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Wen-Jun Zhang ◽  
Zi-Yi Wang ◽  
Wei-Xing Zhou ◽  
Ning-Qiang Yang ◽  
Ya Wang ◽  
...  

Abstract Background We aimed to examine the risk factors for chronic kidney disease (CKD) stage 3 among adults with ASK from unilateral nephrectomy. Methods We retrospectively collected data from adult patients with ASK between January, 2009 and January, 2019, identified from a tertiary hospital in China. The clinical data were compared between patients who developed CKD stage 3 and those who did not develop CKD stage 3 during follow-up. Results In total, 172 patients with ASK (110 men; median 58.0 years) were enrolled, with a median follow-up duration of 5.0 years. During follow-up, 91 (52.9%) and 24 (14.0%) patients developed CKD stage 3 and end-stage renal disease, respectively. Multiple regression analyses showed that age (odds ratio [OR] 1.076, 95% confidence interval [CI] 1.039–1.115, p < 0.001), diabetes (OR 4.401, 95% CI 1.693–11.44, p = 0.002), hyperuricemia (OR 2.733, 95% CI 1.104–6.764, p = 0.03), a history of cardiovascular disease (CVD) (OR 5.583, 95% CI 1.884–18.068, p = 0.002), and ASK due to renal tuberculosis (OR 8.816, 95% CI 2.92–26.62, p < 0.001) were independent risk factors for developing CKD stage 3 among patients with ASK. Conclusions Regular follow-up of renal function is needed among adult patients with ASK. Optimal management of diabetes, hyperuricemia, and CVD may reduce their risk of CKD stage 3, especially among those that undergo unilateral nephrectomy for renal tuberculosis.


Author(s):  
О. Chub ◽  
O. Bilchenko

The aim of the study is to determine the prevalence of plasmid-mediated resistance genes among uro- pathogens from hospitalized patients with chronic pyelonephritis. Methods. A cross-sectional study of 105patients with chronic pyelonephritis and different stage of chronic kidney disease, was carried. Screening for the presence ofplasmid-mediated genes was performed by polymerase chain reaction. Determining the risk factors was performed by analysis of prevalence Odd-ratio. Results. The prevalence of plasmid-mediated resistance mechanisms among uropathogens is 36.7%, mainly due to extended-spectrum p-lactamase (25%). The main factors related with appearance of plasmid-mediated resistance genes were age range above 55 years (OR 3.05), hypertension (OR 2.57), Chronic Kidney Disease stage ІІІ (OR 2,03) and V (OR 1,1), in-patient treatment history (OR 2.02), duration of CP more than 10 years (OR 1,97), history of using antibiotics last year (OR 1,41). Conclusion. Isolation and detection of plasmid-mediated resistance mechanisms among urinary strains are essential for the selection of the most effective antibiotic for the empiric treatment.


2012 ◽  
Vol 38 (1) ◽  
pp. 18-22 ◽  
Author(s):  
M Saha ◽  
MO Faroque ◽  
KS Alam ◽  
MM Alam ◽  
S Ahmed

The study was carried out to see prevalence of Chronic Kidney Disease (CKD) specific cardiovascular risk factors and cardiovascular events among patients with Chronic Kidney Disease stage-V (CKD-V) before starting dialysis therapy in the department of Nephrology of National Institute of Kidney Diseases & Urology (NIKDU), Dhaka, Bangladesh. Among CKD specific cardiovascular risk factors, anemia showed the highest prevalence (96.7%) in study population. More than fifty percent of CKD-V patients had both hypocalcaemia and hyperphosphataemia. Calcium-Phosphate Product (CaXP) was elevated among 23 percent of the population. C-reactive protein, an acute phase protein was positive in 78% of CKD-V patients. Besides, among traditional risk factors, Hypertension and Diabetes Mellitus were present in 83.3% and 23% of the study population respectively. The prevalence of cardiovascular events among CKD-V patients showed that 18.3% had ischemic heart disease, 38% heart failure, 4.7% arrhythmia and 9% left ventricular hypertrophy. Females were significantly prone to develop cardiovascular events than their male counterpart (p=0.028). Diabetes was significantly higher in patients with cardiovascular complications than in patients without cardiovascular complications (p=0.021). DOI: http://dx.doi.org/10.3329/bmrcb.v38i1.10447 Bangladesh Med Res Counc Bull 2012; 38: 18-22


2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii207-iii207
Author(s):  
Simeng Liu ◽  
Peng Xing ◽  
Hong Ren ◽  
Wen Zhang ◽  
Xiaonong Chen ◽  
...  

2020 ◽  
Author(s):  
Jing Chang ◽  
Yan-Fei Wang ◽  
Wen-Wen Hou ◽  
Yan-Chun Li ◽  
Zhuo-Ran Qi ◽  
...  

Abstract Background With the aging of the population, chronic kidney disease (CKD) and sarcopenia are the common diseases among the elderly. Non-dialysis patients with CKD account for a relatively high proportion, and the analysis of their general clinical characteristics has been more familiar. However, the study of sarcopenia in non-dialysis with CKD is not enough. Methods This is a cross sectional study. Non-dialysis patients with CKD stage 3–5 were continuously selected. Patients were divided into 3 groups based on the Fried scale, Non-frail group, Pre-frail group and Frail group. At the same time, muscle mass of the hospitalized patients was measured by dual-energy X-ray absorptiometry (DXA), and according to the test results, they were divided into sarcopenia and non-sarcopenia group. Baseline data and the measurement of the sarcopenia of the two groups were analyzed. Results A total of 102 elderly patients with chronic kidney disease stage 3–5 were continuously enrolled. There were 21 patients (20.6%) categorized as sarcopenia, 81 patients (79.4%) categorized as non-sarcopenia according to the measurement results of DXA. Frailty was assessed by the criteria of frailty phenotype, there were 13 patients of sarcopenia in the frail group, 6 patients of sarcopenia in the pre-frail group, and 2 patients of sarcopenia in the non-frail group, accounting for 31.7%, 20.0%, 6.5%, respectively. Moreover, the analysis of the related risk factors of sarcopenia showed that body mass index (BMI)༜23 kg/m2(OR = 3.82, 95%CI 1.33–10.97, P = 0.013), MNA-SF ≤ 11(OR = 3.97, 95%CI 1.08–14.58, P = 0.038) were the independent risk factors for sarcopenia in non-dialysis patients with chronic kidney disease stage 3–5. Conclusions The prevalence of sarcopenia in elderly non-dialysis patients with chronic kidney disease stage 3–5 was high, and sarcopenia was common in the frail patients. BMI༜23 kg/m2 and MNA-SF ≤ 11were the independent risk factors for sarcopenia in non-dialysis patients with chronic kidney disease stage 3–5.


2012 ◽  
Vol 2 (12) ◽  
pp. 81-84
Author(s):  
Dr. Munna Lal Patel ◽  
◽  
Rekha Sachan ◽  
Dr. Radheshyam Dr. Radheshyam ◽  
Dr. Pushpalata Sachan

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