scholarly journals Precancerous Lesions and Liver Atrophy as Risk Factors for Hepatolithiasis-Related Death after Liver Resection for Hepatolithiasis

2020 ◽  
Vol 21 (12) ◽  
pp. 3647-3654
Author(s):  
Toru Miyazaki ◽  
Hiroji Shinkawa ◽  
Shigekazu Takemura ◽  
Shogo Tanaka ◽  
Ryosuke Amano ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Resection ◽  
Precancerous Lesions ◽  
Liver Atrophy

scholarly journals Impact of Intraoperative Gravity-Dependent Atelectasis Following Laparoscopic Liver Resection Performed in the Lateral Position

2021 ◽  
Author(s):  
Ryoichi Miyamoto ◽  
Toshiro Ogura ◽  
Amane Takahashi ◽  
Akifumi Kimura ◽  
Shinichi Matsudaira ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Resection ◽  
Postoperative Complications ◽  
Laparoscopic Liver Resection ◽  
Operating Time ◽  
Multivariate Logistic Regression Analysis ◽  
Lateral Position ◽  
Cancer Center ◽  
Related Factors ◽  
Left Half

Abstract Purpose Laparoscopic liver resection (LLR) is currently an accepted approach for liver surgery in select patients. The correlation between the intraoperative position and the presence of gravity-dependent atelectasis (GDA) has been well discussed. However, LLR is performed in the left half lateral position, and the relationship between this position and the presence of GDA remains unclear. We evaluated the extent to which the intraoperative left half lateral position affects the presence of GDA. Furthermore, univariate and multivariate analyses were performed to identify potential risk factors for LLR postoperative complications with a special emphasis on the presence of GDA by comparing various patient-, liver- and surgery-related factors in a retrospective cohort. Methods We retrospectively evaluated 129 patients who underwent LLR in the left half lateral position at the Saitama Cancer Center in Saitama, Japan between March 2011 and July 2020. The frequency and duration of GDA were investigated. We divided the cohort into with GDA and without GDA groups based on a cutoff value (≥ 5 days, n = 61 and < 5 days, n = 68, respectively). Using multivariate analysis, the duration of GDA and several risk factors for LLR postoperative complications were independently assessed. Results Postoperative GDA was observed in 61 patients (47%) and lasted for 1 to 8 days in these patients. The mean duration of GDA was 4.3 days. Multivariate logistic regression analysis revealed a GDA duration of 5 days or more (odds ratio [OR], 2.03; p = 0.001) and an operating time > 388 minutes (OR, 5.31; p < 0.001) to be independent risk factors for LLR postoperative complications. Conclusions The incidence and duration of postoperative GDA are considered useful predictors of postoperative complications, and these predictors should be assessed to improve the short-term outcomes of patients undergoing LLR.

scholarly journals Risk factors for surgical site infections after liver resection: A Multivariate Analysis of 6,132 Patients

HPB ◽  
2018 ◽  
Vol 20 ◽  
pp. S290-S291
Author(s):  
L.Y. Sun ◽  
B. Quan ◽  
H. Zhang ◽  
Z.L. Li ◽  
J. Han ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multivariate Analysis ◽  
Liver Resection ◽  
Surgical Site Infections

scholarly journals Risk factors of open conversion in laparoscopic liver resection – a single center study

HPB ◽  
2016 ◽  
Vol 18 ◽  
pp. e240
Author(s):  
W. Cho ◽  
C.H. Kwon ◽  
J.W. Joh ◽  
S.J. Kim ◽  
G.S. Choi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Resection ◽  
Laparoscopic Liver Resection ◽  
Single Center ◽  
Open Conversion ◽  
Single Center Study ◽  
Center Study

scholarly journals Current Tissue Molecular Markers in Colorectal Cancer: A Literature Review

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Gaia Peluso ◽  
Paola Incollingo ◽  
Armando Calogero ◽  
Vincenzo Tammaro ◽  
Niccolò Rupealta ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Molecular Markers ◽  
Ct Colonography ◽  
Precancerous Lesions ◽  
Therapeutic Process ◽  
Cost Effective ◽  
Screening Tests ◽  
Endoscopic Evaluation ◽  
The World

Background. Colorectal cancer (CRC) is one of the most spread neoplasia types all around the world, especially in western areas. It evolves from precancerous lesions and adenomatous polyps, through successive genetic and epigenetic mutations. Numerous risk factors intervene in its development and they are either environmental or genetic.Aim of the Review. Alongside common screening techniques, such as fecal screening tests, endoscopic evaluation, and CT-colonography, we have identified the most important and useful biomarkers and we have analyzed their role in the diagnosis, prevention, and prognosis of CRC.Conclusion. Biomarkers can become an important tool in the diagnostic and therapeutic process for CRC. But further studies are needed to identify a noninvasive, cost-effective, and highly sensible and specific screening test for their detection and to standardize their use in clinical practice.

scholarly journals Severe acute kidney injury following major liver resection without portal clamping: incidence, risk factors, and impact on short-term outcomes

HPB ◽  
2018 ◽  
Vol 20 (9) ◽  
pp. 865-871 ◽  
Author(s):  
Jonathan Garnier ◽  
Marion Faucher ◽  
Ugo Marchese ◽  
Hélène Meillat ◽  
Djamel Mokart ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Liver Resection ◽  
Kidney Injury ◽  
Major Liver Resection ◽  
Short Term ◽  
Incidence Risk

scholarly journals Liver resection: 10-year experience from a single Institution

2004 ◽  
Vol 41 (4) ◽  
pp. 229-233 ◽  
Author(s):  
Julio Cezar Uili Coelho ◽  
Christiano Marlo Paggi Claus ◽  
Tiago Noguchi Machuca ◽  
Wagner Herbert Sobottka ◽  
Carolina Gomes Gonçalves
Keyword(s):  
Risk Factors ◽  
Liver Resection ◽  
Blood Transfusion ◽  
Biliary Leakage ◽  
Median Hospital Stay ◽  
Liver Resections ◽  
Vascular Exclusion ◽  
Life Threatening ◽  
Primary Neoplasms ◽  
Median Hospital

BACKGROUND: Liver resection constitutes the main treatment of most liver primary neoplasms and selected cases of metastatic tumors. However, this procedure is associated with significant morbidity and mortality rates. AIM: To analyze our experience with liver resections over a period of 10 years to determine the morbidity, mortality and risk factors of hepatectomy. PATIENTS AND METHODS: Retrospective review of medical records of patients who underwent liver resection from January 1994 to March 2003. RESULTS: Eighty-three (41 women and 42 men) patients underwent liver resection during the study period, with a mean age of 52.7 years (range 13-82 years). Metastatic colorectal carcinoma and hepatocellular carcinoma were the main indications for hepatic resection, with 36 and 19 patients, respectively. Extended and major resections were performed in 20.4% and 40.9% of the patients, respectively. Blood transfusion was needed in 38.5% of the operations. Overall morbidity was 44.5%. Life-threatening complications occurred in 22.8% of cases and the most common were pneumonia, hepatic failure, intraabdominal collection and intraabdominal bleeding. Among minor complications (30%), the most common were biliary leakage and pleural effusion. Size of the tumor and blood transfusion were associated with major complications (P = 0.0185 and P = 0.0141, respectively). Operative mortality was 8.4% and risk factors related to mortality were increased age and use of vascular exclusion (P = 0.0395 and P = 0.0404, respectively). Median hospital stay was 6.7 days. CONCLUSION: Liver resections can be performed with low mortality and acceptable morbidity rates. Blood transfusion may be reduced by employing meticulous technique and, whenever indicated, vascular exclusion.

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