scholarly journals Laser Therapy as a Preventive Approach for Oral Mucositis in Cancer Patients Undergoing Chemotherapy: The Potential Role of Superoxide Dismutase

2021 ◽  
Vol 22 (10) ◽  
pp. 3211-3217
Author(s):  
Beatriz Menezes ◽  
Marcela Thebit ◽  
Lucas Bonela ◽  
Karine Oliveira ◽  
Washington Gonçalves ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Cancer Patients ◽  
Laser Therapy ◽  
Oral Mucositis ◽  
Potential Role ◽  
Preventive Approach

The potential role of an activity-based guitar program on the anxiety and fulfillment levels of younger relatives of cancer patients: A pilot study

2021 ◽  
pp. 025576142110273
Author(s):  
Erkan Sülün ◽  
Hüseyin Olgaçer ◽  
Hakkı Cengiz Eren
Keyword(s):  
Cancer Patients ◽  
Trait Anxiety ◽  
Potential Role ◽  
Rank Test ◽  
Satisfaction Scale ◽  
Before And After ◽  
Signed Rank Test ◽  
Total State ◽  
Rank Differences

In this study, the authors evaluated the potential role of an activity-based guitar training program on reducing anxiety and providing fulfillment for younger relatives of cancer patients. Ten active members of KHYD (The Society for Relatives of Cancer Patients), between ages 11 and 17 participated in an 8-week guitar education program. The participants filled out two questionnaires before and after their engagement in the 8-week program, one to measure changes in their anxiety levels (State-Trait Anxiety Inventory) and the other to measure changes in their general fulfillment levels (Multidimensional Students’ Life Satisfaction Scale). Wilcoxon signed rank test, as well as descriptive statistics were used in the analysis of data. Mean rank differences were observed to be statistically significant with respect to total state and trait anxiety scores; in both cases, the participants’ scores decreased after their engagement in the program. Statistically significant mean rank differences were also observed in the overall MSLSS scores and its “friends” and “environment” sub-dimensions; with respect to these, participants’ scores increased after their engagement in the program. Recommendations for more comprehensive, larger-scale studies are given at the end.

scholarly journals The potential role of SPECT/CT in the clinical management of COVID-19 lung cancer patients undergoing radiotherapy

2021 ◽  
Author(s):  
Paolo Borghetti ◽  
Cristian Toraci ◽  
Jessica Imbrescia ◽  
Giulia Volpi ◽  
Silvia Lucchini ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Clinical Management ◽  
Potential Role ◽  
Lung Cancer Patients

scholarly journals Exosomic microRNAs as emerging key regulators of intercellular communication in the tumor microenvironment and beyond

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Mariam Murtadha ◽  
Muller Fabbri
Keyword(s):  
Tumor Microenvironment ◽  
Cancer Patients ◽  
Intercellular Communication ◽  
Potential Role ◽  
Biological Fluids ◽  
Healthy Controls ◽  
Gene Regulatory ◽  
Non Coding Rnas ◽  
Regulatory Functions

AbstractMicroRNAs (miRs) are small non-coding RNAs with key gene regulatory functions. Recent evidence has shown that miRs have a central role in shaping the biology of the Tumor Microenvironment (TME). The discovery that some exosomes contain high levels of miR cargo that shuttle between cells and mediate intercellular cross-talk has shifted the focus of miR research towards understanding the biological role of exosomic miRs. In this review, we highlight the emerging role of exosomic miRs in molding the tumor microenvironment towards pro-tumor conditions by altering intercellular communication. We briefly discuss some mechanisms of selective loading of miRs into exosomes, as well as emerging evidence that exosomic miRs are present in all biological fluids. Furthermore, we describe the differences in the exosomic miR signatures between cancer patients and healthy controls, and the potential role of exosomic miRs as diagnostic, prognostic, and therapeutic biomarkers.

Potential Role of the Porcine Superoxide Dismutase 1 (SOD1) Gene in Pig Reproduction

2013 ◽  
Vol 24 (1) ◽  
pp. 1-9 ◽  
Author(s):  
D. Bjerre ◽  
L. B. Madsen ◽  
T. Mark ◽  
S. Cirera ◽  
K. Larsen ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Potential Role ◽  
Superoxide Dismutase 1 ◽  
Sod1 Gene

scholarly journals Clinical potential role of circulating microRNAs in early diagnosis of colorectal cancer patients

2014 ◽  
Vol 35 (12) ◽  
pp. 2723-2730 ◽  
Author(s):  
Mulong Du ◽  
Sang Liu ◽  
Dongying Gu ◽  
Qiaoyan Wang ◽  
Lingjun Zhu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Early Diagnosis ◽  
Cancer Patients ◽  
Potential Role ◽  
Circulating Micrornas ◽  
Colorectal Cancer Patients ◽  
Clinical Potential

Effect of low-level laser therapy on chemoradiotherapy-induced oral mucositis and salivary inflammatory mediators in head and neck cancer patients

2015 ◽  
Vol 47 (4) ◽  
pp. 296-305 ◽  
Author(s):  
Angélica F. Oton-Leite ◽  
Geisa Badauy L. Silva ◽  
Marília O. Morais ◽  
Tarcília A. Silva ◽  
Cláudio R. Leles ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Laser Therapy ◽  
Neck Cancer ◽  
Oral Mucositis ◽  
Inflammatory Mediators ◽  
Low Level Laser Therapy ◽  
Low Level Laser ◽  
Level Laser

Laser therapy for radio-induced oral mucositis and skin dermatitis: Oral medicine, radiotherapy and oncology shared experience from the University of Trieste.

2015 ◽  
Vol 33 (29_suppl) ◽  
pp. 213-213
Author(s):  
Margherita Gobbo ◽  
Alessandra Guglielmi ◽  
Giulia Ottaviani ◽  
Katia Rupel ◽  
Serena Zacchigna ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Laser Therapy ◽  
Oral Mucositis ◽  
Anal Carcinoma ◽  
Life Quality ◽  
Breast Cancer Patients ◽  
Anal Lesions ◽  
The University

213 Background: Oral mucositis (OM) and dermatitis (RD) are serious side effects of radiotherapy (RT), often leading to its suspension, need for analgesics and enteral/parenteral nutrition. Laser-therapy is becoming a recommended option for mucosal lesions and has also been tested for skin affections. This prospective study investigates the effect of Laser-therapy (HPLT) on RT-induced OM and proposes an off-label use of HPLT to treat RD in breast-cancer patients and in RT-treated anal-carcinoma patients Methods: 53 cancer patients, during/after RT and/or chemotherapy, affected by OM, were treated with HPLT during 4 consecutive days (970nm, 2,5W, 35-6000Hz, 240s). Assessment of OM (WHO-SCALE: Grading objective Scale), pain (VAS: Visual Analogue Scale), functional ability, subjective parameters, site/severity of OM were recorded weekly for 21 days. 27 breast-cancer patients and 2 anal-carcinoma patients affected by RD were treated by HPLT every other day for 2 weeks (970nm/660nm, 2-1000Hz, 6W, 480s) and monitored weekly for one month for grade, discomfort, itching and bleeding. Results: Regarding OM, regressive improvement of WHO- SCALE from day 7 on, and of VAS from day 2 on (p < 0.000) was registered. All patients’ functional capacity improved on day 4 (p < 0.05). All subjective parameters improved on day 14 (p < 0.001) except voice, which improved on day 21 (p < 0.000). Ulcerations’ dimension and erythema’s severity decreased in all sites (p < 0.05). Regarding breast and anal RD, after 6 HPLT’s sessions, complete and progressive resolution of pain, bleeding and itching was registered (p < 0.002). All patients referred maximum satisfaction for receiving HPLT. Conclusions: Regardless of OM grade/site and of kind/site of tumor, HPLT was effective in healing OM. Moreover, HPLT resulted an innovative and highly effective therapy for RD, both in breast and anal lesions. To establish an effective treatment strategy for OM and RD is of paramount importance to improve life-quality of patients but can also be beneficial for the continuation of cancer therapy. Consequently, HPLT may become integral part of everyday-practice in the management of RT adverse effects.

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