scholarly journals The use of Decasan in the local treatment of chronic inflammatory diseases of the tonsils

2021 ◽  
Vol 4 (1) ◽  
pp. 18-20
Author(s):  
B. N. Bill ◽  
A. S. Kushnir
Keyword(s):  
Antibiotic Resistance ◽  
Streptococcus Pyogenes ◽  
Inflammatory Diseases ◽  
Effective Means ◽  
Local Treatment ◽  
Viral Pathogens ◽  
Palatine Tonsils ◽  
Chronic Inflammatory Diseases ◽  
Highly Effective ◽  
Systemic Antibiotics

Chronic non-specific inflammatory diseases of the tonsils are predominantly asocialized with bacteria of Streptococcus pyogenes species. However, a mixed microflora, including fungal, is often growing, and tonsillitis can be associated with viral pathogens. Modern antiseptic drug Dekasan, due to its bactericidal, fungicidal, virucidal, sporocidal activity, is a highly effective means for the sanitization of the the palatine tonsils. It can reliably reduce the incidence of tonsillitis, thus reducing the need for systemic antibiotics and will slow the rate of antibiotic resistance.

scholarly journals The  use  of  Decasan  in  the  local  treatment  of  chronic  inflammatory diseases of the tonsils

2021 ◽  
Vol 4 (2) ◽  
pp. 17-22
Author(s):  
B Bill ◽  
A Kushnir
Keyword(s):  
Inflammatory Diseases ◽  
Local Treatment ◽  
Recurrent Tonsillitis ◽  
Palatine Tonsils ◽  
Chronic Inflammatory Diseases ◽  
Clinical Observations ◽  
Normal Microflora ◽  
Highly Effective

The local sanitation in 40 patients with recurrent tonsillitis was carried out, using Decasan for washing of the lacunae of the palatine tonsils. Clinical observations and bacteriological studies have shown greater efficacy of Decasan in relation to the main pathogens of the tonsillar lacunae, compared to antibiotic solutions traditionally used for washing. Decasan is a highly effective and safe antiseptic for local treatment of patients with chronic inflammatory diseases of the tonsils, contributing to the restoration of local biocenosis, which is confirmed by an increase in the plaiting of normal microflora from the surface of the tonsillar lacunae.

scholarly journals The effectiveness of Dekasan for prevention of postoperative complications after major bone surgeries

2021 ◽  
Vol 4 (2) ◽  
pp. 33-35
Author(s):  
A Kalashnikov ◽  
O Kalashnikov ◽  
Yu Stavinskiy ◽  
Yu Litun ◽  
Yu Khodakovsky
Keyword(s):  
Antibiotic Resistance ◽  
Postoperative Complications ◽  
Highly Effective ◽  
Systemic Antibiotics

Antiseptic drug “Decasan” due to its bactericidal, fungicidal, viricidal and sporicidal action is a highly effective medicine for the prevention of postoperative complications in an orthopedic and trauma hospital. Its use can significantly reduce the frequency of complications, and thus reduces the need for systemic antibiotics and slows down the develop-ment of antibiotic resistance.

scholarly journals The influence of parenteral influenza vaccination on local immunity indices and microbiota of oropharyngeal secretion in patients with chronic inflammatory diseases of the upper respiratory tract

2021 ◽  
Vol 26 (4) ◽  
pp. 104-112
Author(s):  
D.I. Zabolotny ◽  
O.F. Melnikov ◽  
S.V. Timchenko ◽  
M.B. Sambur ◽  
O.G. Rylska ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Influenza Vaccination ◽  
Influenza A ◽  
Inflammatory Diseases ◽  
Effective Means ◽  
Interferon Α ◽  
Upper Respiratory Tract ◽  
Local Immunity ◽  
Chronic Inflammatory Diseases ◽  
Upper Respiratory

When studying the effect of vaccines against influenza, attention is mainly paid to obtaining high titers of protective antibodies in the blood and reducing the incidence of respiratory infections among vaccinated people. At the same time, the changes  occurring in patient,s body from the factors of local specific and innate immunity remain insufficiently studied. The aim of the study was to determine the effect of parenteral influenza vaccination on the state of local immunity, cytology and microbiota of oropharyngeal secretion (OS) in patients with chronic inflammatory diseases of the upper respiratory tract. The study of immunological and microbiological parameters was performed in 32 patients with chronic inflammatory diseases of the upper respiratory tract, including 11 diagnosed with chronic rhinosinusitis, 9 – with chronic tonsillitis, 12 – with chronic pharyngitis, 3 and 12 weeks after vaccination with trivalent inactivated influenza-vaccine (PASTEUR, SA, France), which was administered intramuscularly. Single vaccination against influenza A and B has been shown to normalize reduced local humoral immunity indices, in particular sIgA and immune complexes concentrations, increase lymphocyte output to oropharyngeal secretions and cause a significant decrease in the representation of OS transient microflora without affecting the overall level of bacterial contamination. In both periods after the vaccination the reduced content of interferon-α in the OS of patients with chronic inflammatory diseases of the upper respiratory tract did not change. The obtained data allow to recommend vaccination against influenza virus in the period up to 3 months before the the beginning of mass infections as an effective means of stimulating the protective reactions of local immunity of oropha­rynx and nasopharynx mucous membranes in patients with chronic inflammatory diseases of the upper respiratory tract.

Use of a drug containing ornidazole-neomycin–prednisolone–econazole for the empirical treatment of vaginal infections

GYNECOLOGY ◽  
2020 ◽  
Vol 22 (4) ◽  
pp. 28-32
Author(s):  
Valerii G. Volkov ◽  
Tatyana V. Zakharova
Keyword(s):  
Inflammatory Diseases ◽  
Local Treatment ◽  
Empirical Treatment ◽  
New Combination ◽  
Microbiological Analysis ◽  
Vaginal Infections ◽  
Aerobic Vaginitis ◽  
Burning Pain ◽  
Lower Genital Tract ◽  
Unpleasant Smell

Relevance. Empirical treatment of vaginitis is indicated due to its polymicrobial etiology and limited microbiological analysis. The aim of the study was to study the combination of ornidazoleneomycinprednisoloneeconazole (ONPE, Elzhina) as a first-line drug for local treatment of patients with various forms of non-specific vaginitis. Materials and methods. The study included 55 non-pregnant women aged 18 to 50 years (381.5 years) who had clinical and laboratory signs of acute vaginitis. Results. All patients at the initial treatment complained of pathological discharge, 47 (85.5%) noted itching, burning, pain in the genital area of various degrees of severity, 17 (30.9%) discomfort when urinating, 9 (16.4%) unpleasant smell, 8 (14.5%) dyspareunia, 4 (2.2%) complained of sensations of a foreign body in the vagina. The clinical and laboratory effectiveness of treatment was 89.1% (49). In 6 (10.9%) patients, clinical improvement was noted, with the remaining laboratory signs of aerobic vaginitis. Conclusion. The new combination of ornidazoleneomycinprednisoloneeconazole (ONPE, Elzhina ) has a good efficacy and safety profile and can be used to initiate empirical treatment of non-specific inflammatory diseases of the lower genital tract.

Antibiotic resistance in urological patients with inflammatory diseases of the upper urinary tract

2019 ◽  
Vol 11 (2) ◽  
pp. 106-110
Author(s):  
A.B. Bochkarev ◽  
◽  
S.V. Kostuykov ◽  
E.I. Shamatrina ◽  
D.S. Merinov ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Inflammatory Diseases ◽  
Upper Urinary Tract

Antibiotic Resistance

2017 ◽  
Author(s):  
Jessica Litman
Keyword(s):  
Antibiotic Resistance ◽  
Content Distribution ◽  
Significant Risk ◽  
Copyright Infringement ◽  
Online Content ◽  
30Th Anniversary ◽  
Secure Control ◽  
Highly Effective ◽  
New Entrants ◽  
War Stories

In this essay, written for the 30th Anniversary of Cardozo’s Arts and Entertainment Law Journal, I revisit the ruinous litigation strategy copyright owners pursued after Napster to secure control of the market for personal uses of copyrighted works, which I wrote about ten years ago in War Stories, 20 Cardozo Arts & Ent. L.J. 337 (2002). The litigation campaign had effects that copyright owners now have reason to regret. Medical experts tell us that powerful antibiotics are highly effective in killing off both good and bad bacteria, but at a significant risk. Bugs that survive the treatment grow bigger, stronger, and resistant to antibiotics. They become much more dangerous because they are harder to kill. Copyright owners’ indiscriminate litigation against new entrants into the entertainment and information marketplace killed off a broad swath of potential competitors and partners. The ones who were left faced a less crowded field because old media had helpfully cleared it for them. The scorched-earth litigation strategy temporarily cleared the field, and made room both for tepid, content-industry-controlled efforts to distribute music, books, and video online, and for new entrants with the stamina and resources to survive copyright infringement suits. Apple, Amazon, and Google took advantage of that environment to grow into dominant distributors who are obligatory partners for any serious online content distribution plan, and who insist on calling the shots on price, format, and other matters that content owners believe should rightfully be under their own control.

Chronic Inflammatory Diseases: Progress and Prospect with Herbal Medicine

2015 ◽  
Vol 22 (2) ◽  
pp. 247-264 ◽  
Author(s):  
Nilanjan Ghosh ◽  
Asif Ali ◽  
Rituparna Ghosh ◽  
Shaileyee Das ◽  
Subhash C. Mandal ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Inflammatory Diseases ◽  
Chronic Inflammatory Diseases

Exploiting Anti-Inflammation Effects of Flavonoids in Chronic Inflammatory Diseases

2020 ◽  
Vol 26 (22) ◽  
pp. 2610-2619 ◽  
Author(s):  
Tarique Hussain ◽  
Ghulam Murtaza ◽  
Huansheng Yang ◽  
Muhammad S. Kalhoro ◽  
Dildar H. Kalhoro
Keyword(s):  
Oxidative Stress ◽  
Chronic Diseases ◽  
Inflammatory Diseases ◽  
Therapeutic Option ◽  
Cellular Level ◽  
Antiinflammatory Drugs ◽  
Suitable Alternative ◽  
Chronic Inflammatory Diseases

Background: Inflammation is a complex response of the host defense system to different internal and external stimuli. It is believed that persistent inflammation may lead to chronic inflammatory diseases such as, inflammatory bowel disease, neurological and cardiovascular diseases. Oxidative stress is the main factor responsible for the augmentation of inflammation via various molecular pathways. Therefore, alleviating oxidative stress is effective a therapeutic option against chronic inflammatory diseases. Methods: This review article extends the knowledge of the regulatory mechanisms of flavonoids targeting inflammatory pathways in chronic diseases, which would be the best approach for the development of suitable therapeutic agents against chronic diseases. Results: Since the inflammatory response is initiated by numerous signaling molecules like NF-κB, MAPK, and Arachidonic acid pathways, their encountering function can be evaluated with the activation of Nrf2 pathway, a promising approach to inhibit/prevent chronic inflammatory diseases by flavonoids. Over the last few decades, flavonoids drew much attention as a potent alternative therapeutic agent. Recent clinical evidence has shown significant impacts of flavonoids on chronic diseases in different in-vivo and in-vitro models. Conclusion: Flavonoid compounds can interact with chronic inflammatory diseases at the cellular level and modulate the response of protein pathways. A promising approach is needed to overlook suitable alternative compounds providing more therapeutic efficacy and exerting fewer side effects than commercially available antiinflammatory drugs.

scholarly journals Lipid, fatty acid, carnitine- and choline derivative profiles in rheumatoid arthritis outpatients with different degrees of periodontal inflammation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kathrin Beyer ◽  
Stein Atle Lie ◽  
Bodil Bjørndal ◽  
Rolf K. Berge ◽  
Asbjørn Svardal ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Fatty Acid ◽  
Mitochondrial Dysfunction ◽  
Inflammatory Diseases ◽  
Whole Body ◽  
Cross Sectional ◽  
Chronic Inflammatory Diseases ◽  
Periodontal Inflammation ◽  
Inflammatory Status ◽  
Lipid Fatty Acid

AbstractRheumatoid arthritis (RA) and periodontitis are chronic inflammatory diseases with several pathogenic pathways in common. Evidence supports an association between the diseases, but the exact underlying mechanisms behind the connection are still under investigation. Lipid, fatty acid (FA) and metabolic profile alterations have been associated with several chronic inflammatory diseases, including RA and periodontitis. Mitochondria have a central role in regulating cellular bioenergetic and whole-body metabolic homeostasis, and mitochondrial dysfunction has been proposed as a possible link between the two disorders. The aim of this cross-sectional study was to explore whole-blood FA, serum lipid composition, and carnitine- and choline derivatives in 78 RA outpatients with different degrees of periodontal inflammation. The main findings were alterations in lipid, FA, and carnitine- and choline derivative profiles. More specifically, higher total FA and total cholesterol concentrations were found in active RA. Elevated phospholipid concentrations with concomitant lower choline, elevated medium-chain acylcarnitines (MC-AC), and decreased ratios of MC-AC and long-chain (LC)-AC were associated with prednisolone medication. This may indicate an altered mitochondrial function in relation to the increased inflammatory status in RA disease. Our findings may support the need for interdisciplinary collaboration within the field of medicine and dentistry in patient stratification to improve personalized treatment. Longitudinal studies should be conducted to further assess the potential impact of mitochondrial dysfunction on RA and periodontitis.

Sign in / Sign up

Export Citation Format

Share Document