scholarly journals The effectiveness of Dekasan for prevention of postoperative complications after major bone surgeries

2021 ◽  
Vol 4 (2) ◽  
pp. 33-35
Author(s):  
A Kalashnikov ◽  
O Kalashnikov ◽  
Yu Stavinskiy ◽  
Yu Litun ◽  
Yu Khodakovsky
Keyword(s):  
Antibiotic Resistance ◽  
Postoperative Complications ◽  
Highly Effective ◽  
Systemic Antibiotics

Antiseptic drug “Decasan” due to its bactericidal, fungicidal, viricidal and sporicidal action is a highly effective medicine for the prevention of postoperative complications in an orthopedic and trauma hospital. Its use can significantly reduce the frequency of complications, and thus reduces the need for systemic antibiotics and slows down the develop-ment of antibiotic resistance.

scholarly journals The use of Decasan in the local treatment of chronic inflammatory diseases of the tonsils

2021 ◽  
Vol 4 (1) ◽  
pp. 18-20
Author(s):  
B. N. Bill ◽  
A. S. Kushnir
Keyword(s):  
Antibiotic Resistance ◽  
Streptococcus Pyogenes ◽  
Inflammatory Diseases ◽  
Effective Means ◽  
Local Treatment ◽  
Viral Pathogens ◽  
Palatine Tonsils ◽  
Chronic Inflammatory Diseases ◽  
Highly Effective ◽  
Systemic Antibiotics

Chronic non-specific inflammatory diseases of the tonsils are predominantly asocialized with bacteria of Streptococcus pyogenes species. However, a mixed microflora, including fungal, is often growing, and tonsillitis can be associated with viral pathogens. Modern antiseptic drug Dekasan, due to its bactericidal, fungicidal, virucidal, sporocidal activity, is a highly effective means for the sanitization of the the palatine tonsils. It can reliably reduce the incidence of tonsillitis, thus reducing the need for systemic antibiotics and will slow the rate of antibiotic resistance.

Antibiotic Resistance

2017 ◽  
Author(s):  
Jessica Litman
Keyword(s):  
Antibiotic Resistance ◽  
Content Distribution ◽  
Significant Risk ◽  
Copyright Infringement ◽  
Online Content ◽  
30Th Anniversary ◽  
Secure Control ◽  
Highly Effective ◽  
New Entrants ◽  
War Stories

In this essay, written for the 30th Anniversary of Cardozo’s Arts and Entertainment Law Journal, I revisit the ruinous litigation strategy copyright owners pursued after Napster to secure control of the market for personal uses of copyrighted works, which I wrote about ten years ago in War Stories, 20 Cardozo Arts & Ent. L.J. 337 (2002). The litigation campaign had effects that copyright owners now have reason to regret. Medical experts tell us that powerful antibiotics are highly effective in killing off both good and bad bacteria, but at a significant risk. Bugs that survive the treatment grow bigger, stronger, and resistant to antibiotics. They become much more dangerous because they are harder to kill. Copyright owners’ indiscriminate litigation against new entrants into the entertainment and information marketplace killed off a broad swath of potential competitors and partners. The ones who were left faced a less crowded field because old media had helpfully cleared it for them. The scorched-earth litigation strategy temporarily cleared the field, and made room both for tepid, content-industry-controlled efforts to distribute music, books, and video online, and for new entrants with the stamina and resources to survive copyright infringement suits. Apple, Amazon, and Google took advantage of that environment to grow into dominant distributors who are obligatory partners for any serious online content distribution plan, and who insist on calling the shots on price, format, and other matters that content owners believe should rightfully be under their own control.

scholarly journals Topical issues of inhaled antibacterial therapy of respiratory diseases in children

2018 ◽  
pp. 128-131 ◽  
Author(s):  
N. G. Kolosova ◽  
A. B. Kolosova
Keyword(s):  
Antibiotic Resistance ◽  
Antibiotic Therapy ◽  
Respiratory Diseases ◽  
Respiratory Infections ◽  
Infectious Agents ◽  
Antibiotic Resistant ◽  
Restriction Policy ◽  
Resistant Strains ◽  
Outpatient Practice ◽  
Systemic Antibiotics

Despite the fact that acute respiratory infections have viral etiology, the frequency of antibiotic prescriptions accounts for more than 70% in outpatient practice. However, the preventive administration of systemic antibiotics does not reduce the duration of the disease and the incidence of bacterial complications. In addition, the irrational use of antibiotic therapy can lead to the development of antibiotic resistance of infectious disease pathogens. The global problem of antibiotic resistance is seen as a serious threat to public health, and therefore the systemic antibiotic restriction policy is crucial, which helps to reduce the formation of antibiotic-resistant strains of infectious agents. The possibility of using local antibacterial drugs enables optimization of antibiotic therapy and reduces the risk of the development of antibiotic resistance. The article discusses the issues of use of thiamphenicol glycinate acetylcysteinate in various diseases in children.

scholarly journals Antibiotics usage, how well we know it? KAP survey among the dentist population in Mumbai

2020 ◽  
Vol 9 (11) ◽  
pp. 1713
Author(s):  
Amisha N. Parekh ◽  
Karthik Balasubramanian ◽  
Purvi Bhate ◽  
Dheeraj D. Kalra
Keyword(s):  
Antibiotic Resistance ◽  
Antimicrobial Stewardship ◽  
Antibiotic Sensitivity ◽  
Chi Square ◽  
Cross Sectional ◽  
Antibiotic Overuse ◽  
Total Percentage ◽  
Dental Practitioners ◽  
Chi Square Test ◽  
Systemic Antibiotics

Background: There is a rising concern for antibiotic resistance worldwide, the primary cause of which is overuse and misuse. This study primarily aimed at assessing the knowledge of dental practitioners regarding the current guidelines on use of antibiotics and to identify the shortcomings if any.Methods: Present study was a cross-sectional questionnaire-based study conducted amongst 450 dental practitioners across Mumbai with the help of a self-designed questionnaire. The data was entered into excel sheets and appropriate statistical analysis was done with chi-square test using SPSS version 20.Results: The present study had a response rate of 95%. For the total percentage of patients examined each day that required systemic antibiotics, 36.9% (153) dentists answered 0-5%, followed by 25.3% (105) answered 10-15%. 76.1% (316) dentists came across patients who had self-prescribed antibiotics. 66% (274) dentists had never advised an antibiotic sensitivity/ culture test for their patients. 51.3% (213) dentists came across patients who did not respond to antibiotics. 87.2% (363) dentists were not aware about the ‘AWaRe’ classification of antibiotics given by WHO. 93.3% (383) dentists did not know about antimicrobial stewardship concept.Conclusions: The present study reflected antibiotic overuse and misuse to a certain extent by dental practitioners across Mumbai. Most dentists were unaware about ‘AWaRe’ classification and antimicrobial stewardship. Patient education on ill effects of self-prescription of antibiotics, identification of traits of antibiotic resistance and antibiotic culture tests needs to be prioritized by dentists.

scholarly journals MODERN APPROACH TO ANTIBACTERIAL THERAPY IN THE PRACTICE OF A SURGEON

2021 ◽  
Author(s):  
A. M. Morozov ◽  
A. N. Sergeev ◽  
E. M. Askerov ◽  
S. V. Zhukov ◽  
N. S. Novikova ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Postoperative Complications ◽  
Antibacterial Therapy ◽  
New Drugs ◽  
Antibacterial Prophylaxis ◽  
Russian Science ◽  
Antibacterial Drugs ◽  
Modern Approach ◽  
Surgical Practice ◽  
Russian Science Citation Index

Relevance. Currently, all over the world, antibacterial therapy is widely used as a prophylaxis after surgical interventions. Currently, some data indicate the benefits of a short course, while others, in turn, indicate the benefits of a long course of antibacterial drugs as a prevention of postoperative complications. The problem of pan-resistance of bacterial strains in relation to almost all available groups of antibacterial drugs forces us to look for ways to overcome resistance, to look for new potential bases for the creation of antimicrobial drugs. New antibacterial drugs: odilorhabdins, tridecapeptins and malacidins, arilomycins and others will help to overcome the existing difficulties.The purpose of this study is to analyze the domestic and foreign literature for the period 2017–2021 in order to study the current approach to antibacterial therapy in surgical practice.Material and methods. In the course of this study, publications were selected according to the topic for the period from 2017 to 2021. The information was obtained from foreign and domestic sources: the Russian scientific electronic library, integrated with the Russian Science Citation Index (eLibrary.ru), Medline database (via Pubmed.gov), Scopus database, ScienceDirect database.Results. One of the significant difficulties in the treatment of wounds with antibacterial drugs of various localizations is the persistence of resistant strains of Staphylococcus aureus. In the studied studies, the high effectiveness of tedizolide phosphate in the treatment of this type of infection was noted. It is also possible to use other new drugs as epmiric therapy in the presence of risk factors for MRSA infection: daptomycin (lipopeptides), ceftaroline (cephalosporins), tigecycline (glycylcyclines), telavancin (glycopeptides)[41]. The use of biocides in the treatment of prostheses for hernioplasty as an antibacterial prophylaxis significantly reduces the adhesion of staphylococci and prevents postoperative complications. Suture material with antimicrobial activity, which would allow to fully reduce the risk of infections in the field of surgical intervention, is not yet available on the pharmaceutical market, but the increasing attention of scientists is attracted by chitosan, a derivative of the natural polymer chitin. The combined use of bacteriophages with low doses of antibiotics leads to better results in the treatment of surgical soft tissue infection. Bacteriophages are one of the ways to overcome antibiotic resistance.Conclusions. The modern approach to antibacterial therapy in surgical practice involves the correct and timely appointment of starting therapy, taking into account the sensitivity of microorganisms, the use of antibacterial preoperative prevention, determining the optimal duration of use and dose selection of an antibiotic, the use of sensitive bacteriophages together with them, overcoming antibiotic resistance due to the competent use of new antibacterial drugs based on peptides, a comprehensive approach to the treatment of surgical infection.

Silver nanoflower coupled with low dose antibiotics enables highly effective Drug-resistant bacteria eradication

2021 ◽  
Author(s):  
Xin Li ◽  
Xianting Ding ◽  
Khan Zara Ahmad ◽  
Jie He ◽  
Hongxia Li ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Low Dose ◽  
Multidrug Resistant ◽  
Effective Drug ◽  
Resistant Bacteria ◽  
Drug Resistant ◽  
Multidrug Resistant Bacteria ◽  
Effective Strategies ◽  
Drug Resistant Bacteria ◽  
Highly Effective

Due to the global overuse of antibiotics, multidrug-resistant bacteria (MDR) continuously call for effective strategies to tackle the antibiotic resistance crisis. Here, we develop a silver nanomaterial with a petal-like...

scholarly journals Multidirectional inhalation therapy of acute rhinosinusitis

2019 ◽  
pp. 28-32
Author(s):  
S. V. Morozova ◽  
V. M. Svistushkin ◽  
L. S. Karapetyan
Keyword(s):  
Antibiotic Resistance ◽  
Side Effects ◽  
Russian Federation ◽  
Bacterial Pathogens ◽  
Inhalation Therapy ◽  
Acute Rhinosinusitis ◽  
The Russian Federation ◽  
Systemic Antibiotics

In the article is discussed the problem of antibiotic resistance, widespread and not always justified use of systemic antibiotics in the treatment of acute rhinosinusitis. The main spectrum of bacterial pathogens of acute rhinosinusitis, their sensitivity and resistance are showed, including in the Russian Federation. Presents topical inhalational drug Fluimucil IT contains mucolitic and antibiotic as a possible replacement of systemic antibiotics, in conjunction with its better tolerability, including in children, and less pronounced side effects.

Oral budenosid is highly effective in the treatment of collagenous colitis: A randomized, double-blind, placebo-controlled, multicenter trial

2001 ◽  
Vol 120 (5) ◽  
pp. A40-A40 ◽  
Author(s):  
S MIEHLKE ◽  
P HEYMER ◽  
T OCHSENKUEHN ◽  
E BAESTLEIN ◽  
G YARIAN ◽  
...  
Keyword(s):  
Collagenous Colitis ◽  
Multicenter Trial ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Highly Effective
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