Plantes médicinales utilisées contre le cancer du sein par la population d’Algérie de l’Est

2021 ◽  
Author(s):  
K. Ounaissia ◽  
R. Bechiri ◽  
M. Snani ◽  
L. Naoun
Keyword(s):  
Nous Avons ◽  
Cancer Du Sein ◽  
Allium Sativum ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Plantes Médicinales ◽  
Annona Muricata ◽  
Berberis Vulgaris ◽  
Étude Ethnobotanique

Une étude ethnobotanique des plantes médicinales utilisées traditionnellement dans le traitement du cancer du sein a été menée en 2018–2019 auprès des patients du service de radiothérapie, « centre anticancer, CAC », Annaba, Algérie. Cette étude a permis de réunir toutes les informations concernant l’usage des plantes médicinales pratiqué par les malades. L’analyse des résultats, obtenus à partir de fiches questionnaires, a permis de recenser 35 espèces végétales réparties dans 27 familles botaniques, avec une représentation importante des espèces suivantes : Nigella sativa L. (12 citations), Curcuma longa L., Allium sativum L., Berberis vulgaris L., Annona muricata L., Ephedra sp (neuf citations), suivies par le Zingiber officinale Roscoe (huit citations), le reste des espèces ont une fréquence de citation comprise entre une et sept. Nous avons noté aussi que parmi les organes des plantes, le feuillage constitue la partie la plus utilisée, avec un pourcentage de 20 %. Toutes ces informations constituent une ébauche importante pour réaliser des recherches expérimentales ultérieures dans le but de déterminer les principes actifs et leurs mécanismes d’action sur le cancer.

Efficacy of Allium Sativum, Curcuma Longa and Zingiber Officinale Extract on Serum Vasculoendothelial Growth Factors Levels of Breast Cancer Patients

2021 ◽  
Vol 8 (10) ◽  
pp. 396-401
Author(s):  
Michael Yang ◽  
Dairion Gatot ◽  
Andri Iskandar Mardia
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Allium Sativum ◽  
Complete Blood Count ◽  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Serum Levels ◽  
Breast Cancer Patients ◽  
Open Label ◽  
Before And After

ntroduction: Breast cancer requires high nutrition, oxygen and metabolism where VEGF-triggered angiogenesis is needed. VEGF is triggered via the HIF-1 pathway and also via the NF-Kappa B pathway. VEGF is associated with tumor growth and metastasis. Some plant extracts have anti-angiogenesis effects such as Curcuma longa, Allium sativum and Zingiber officinale. Objective: To determine serum levels of SGOT, SGPT, ureum, creatinine, albumin and VEGF before and after administration of Curcuma longa, Allium sativum and Zingiber officinale extracts Method: An open label clinical trial study with a one group pretest posttest design involving 21 patients from breast cancer community in Medan collected by consecutive sampling from June – July 2021 in USU hospital where these patients met the inclusion criteria. All patients were tested for complete blood count, urea, creatinine, SGOT, SGPT, albumin, serum VEGF before and after being given a combination extract of Curcuma longa 150 mg, Allium sativum 200 mg and Zingiber officinale 150 mg twice daily for 28 days. Statistical analysis was performed by paired analytical T test or Wilcoxon. Results: The study involved 20 subjects. From the examination of kidney function obtained results before and after the administration of a combination extract VEGF results before and after the administration of the combination (1110(760-7893) μg / ml vs. 864 (532-5650 μg / ml, p = 0.001). Conclusion: VEGF serum breast cancer patients had a significant reduction after being given a combination of extracts of Allium sativum, Curcuma longa and Zingber officinale. Keywords: VEGF, Allium sativum, Curcuma longa, Zingiber officinale.

scholarly journals Review of Antiviral Medicinal Plants used in Taraba State Nigeria: A Possible Source for COVID-19 Drug Discovery

2020 ◽  
Vol 1 (2) ◽  
pp. 1-23
Author(s):  
Cletus Anes Ukwubile ◽  
Troy Silvia Malgwi ◽  
Alexander Ezekiel Angyu ◽  
Otalu Otalu ◽  
Mathias Simon Bingari
Keyword(s):  
Medicinal Plants ◽  
Allium Sativum ◽  
Viral Infections ◽  
Curcuma Longa ◽  
Antiviral Agents ◽  
Zingiber Officinale ◽  
Human Influenza Virus ◽  
Infectious Bronchitis ◽  
The Usa ◽  
Ocimum Tenuiflorum

Purpose: Coronavirus also known as COVID-19 is a viral infection that has been tagged as the greatest pandemic since the existence of humans by the WHO, resulting in the deaths of thousands of people globally; with the USA one of the highest. The full biology of the virus is yet to be known. This study reviews sixteen natural antiviral plants used in Taraba State to manage viral infections locally. Subjects and Methods: Sixteen medicinal plants popularly used as antiviral agents in Taraba State, Nigeria were surveyed based on a field-trip experience with herbal medicine practitioners in the three zones of the state. Plants that were in both zones were counted as the same. The plants that are majorly used for various viral infections are Allium sativum, Zingiber officinale, Camellia sinensis, Hibiscus sabdariffa, Cirus lemon, Azardirachta indica, Ocimum tenuiflorum, Curcuma longa, Haematostaphis barteri, Olea europaea, Melastomastrum capitatum, Astragalus canadensis, Carissa edulis, Spondias venulosa, Vitellaria paradoxa, and Euphorbia hirta. Results: Of the sixteen plants, ten have been reported to have antiviral properties against at least one of these viruses avian or bird flu, human influenza virus, infectious bronchitis virus (a type of coronavirus), herpes virus, hepatitis C virus and HIV. Conclusion: The study revealed that further research on these antiviral plants used traditionally might pave the way for the discovery of potent antiviral drugs against COVID-19.

Natural Products and their Promise against COVID 19: Review

2021 ◽  
Vol 17 ◽  
Author(s):  
Fatma Abo-Elghiet ◽  
Hanan M. Alharbi ◽  
Abeer Temraz
Keyword(s):  
Respiratory Infections ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Punica Granatum ◽  
Echinacea Purpurea ◽  
In Vivo Studies ◽  
Traditional Treatment ◽  
Global Health Problem

Background: Since the beginning of medical history, plants have been exemplary sources of a variety of pharmacological compounds that are still used in modern medication. Respiratory infections are a serious and persistent global health problem, most acute and chronic respiratory infections are caused by viruses, whose ability to rapidly mutate may result in epidemics and pandemics, as seen recently with MERS-COV (2012) and SARS-COV-2 (2019), the latter causing coronavirus disease 2019 (COVID-19). Methods: Highlight the tremendous benefits of plants that have been widely used as dietary supplements or traditional treatment for various respiratory infections, with a focus on the most effective constituents and studies that revealed their activities against COVID-19. Results: Several traditional plants and their phytoconstituents have shown activity against respiratory viruses, including SARS-COV-2. The presented plants are Nigella sativa, Punica granatum, Panax ginseng, Withania somnifera, Glycyrrhiza glabra, Curcuma longa, Zingiber officinale, Camellia sinensis, Echinacea purpurea, Strobilanthes cusia, Stephania tetrandra, and genus Sambucus. Conclusion: The data discussed in this review can encourage carrying out in-vivo studies that may help to the discovery of herbal leads that can be feasibly used to alleviate, prevent or treat COVID-19 infection.

scholarly journals A Review on Efficacy of Siddha Medicinal Herbs as Antiviral Drugs against COVID-19

2021 ◽  
Vol 12 (1) ◽  
pp. 1-6
Author(s):  
Muralidass S D ◽  
Shree Devi M S
Keyword(s):  
Infectious Disease ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Antioxidant Properties ◽  
Herbal Medicines ◽  
Zingiber Officinale ◽  
World Health ◽  
Tinospora Cordifolia ◽  
Piper Nigrum ◽  
Ocimum Sanctum

In a very short time, the Coronavirus disease (COVID-19) caused by the SARS-CoV-2 virus, has become a global pandemic. It has infected about 29,155,581 patients and brought forth death rate about 926,544 among 216 countries as recorded by World Health Organization on 15th September 2020. At present, there is no specific and direct treatment or vaccine for this infectious disease. No therapeutic options available to cure the infection in till date which increases the mortality rate across the countries. Currently there is no antiviral treatments have been approved, several approaches have been proposed in western medicine, Chinese medicine, CAM, AYUSH and other systems. Siddha Herbal medicines are achieving high attention because of the extensive therapeutics like potent anti-microbial, immunomodulatory, anti-inflammatory, and antioxidant properties. Ministry of AYUSH, Govt. of India recommended 12 Siddha herbals (Inji – Zingiber officinale, Thulasi – Ocimum sanctum, Milaku – Piper nigrum, Karunjeeragam – Nigella sativa, Keezhanelli – Phyllanthus niruri, Adhimathuram – Glycyrrhiza glabra, Vellaippoondu – Allium sativum, Citramutti – Sida cardifolia, Seenthil – Tinospora cordifolia, Manjal – Curcuma longa, Elumitchai – Citrus lemon and Vembu – Azadirachta indica) for the prevention by enhancing immunity as well as for the management of this infectious disease in its recent official publication ‘Guidelines for Siddha Practitioners for COVID 19’. This is the common advisory and the anti-viral activity of these herbals against COVID 19 is not established yet. The current situation demands proper herbal drug utilization to prepare the population immunity to fight against the infection. The present review spotlight on the literature review and the review of pharmacological actions of these herbals.

scholarly journals Evaluation of anti-dermatophytic activity of medicinal plants derived products

2020 ◽  
Vol 7 (1) ◽  
pp. 28
Author(s):  
Anu Gupta ◽  
Alisha . ◽  
Sandeep Kaur ◽  
Prabhjot Kaur Gill
Keyword(s):  
Medicinal Plants ◽  
Azadirachta Indica ◽  
Allium Sativum ◽  
Curcuma Longa ◽  
Cocos Nucifera ◽  
Zingiber Officinale ◽  
Melaleuca Alternifolia ◽  
Keratinized Tissue ◽  
Dermatophyte Species ◽  
Citrus Limonum

<p class="abstract"><strong>Background: </strong>Dermatophytes are a group of closely related fungi which are able to invade the keratinized tissue skin, hair and nail. In this study different medicinal plants like <em>Melaleuca alternifolia, Zingiber officinale, Allium sativum, Azadirachta indica, Citrus limonum, Curcuma longa, Cocos nucifera</em> were used as antifungal agent against different dermatophyte species.</p><p class="abstract"><strong>Methods: </strong>A hospital-based study consisting of 320 patients clinically diagnosed having dermatophytic infection who reported to the Dermatology outpatient department (OPD), Adesh medical college, Bathinda was conducted for the period of 2 years. Socio-demographic and clinical information was collected and sample was taken from the edge of infected area which was then collected in 2 ml of Eppendorf. Extracts of medicinal plants were then explored against dermatophyte. The data was evaluated using appropriate statistical method.</p><p class="abstract"><strong>Results: </strong>All dermatophyte species were found sensitive for <em>Melaleuca alternifolia, Zingiber officinale and Allium sativum</em>. These medicinal plants showed very good results as antifungal against dermatophytes while <em>Azadirachta indica </em>and <em>Citrus limonum </em>were moderate sensitive and <em>Curcuma longa </em>and <em>Cocos nucifera </em>did not show any zone of inhibition around the well.</p><p class="abstract"><strong>Conclusions: </strong>This research provides a scientific validation for the use of these medicinal plants in the treatment of dermatophytic infection and could be used in future for dermatophytic infection and other skin infection.</p>

scholarly journals Determinación de la actividad biocida de extractos vegetales para el combate de la mosca blanca Bemisia tabaci (Hemíptera: Aleyrodidae)

2020 ◽  
Author(s):  
Lucía Rodríguez-Montero ◽  
Alexander Berrocal-Jiménez ◽  
Rooel Campos-Rodríguez ◽  
Mairon Madriz-Martínez
Keyword(s):  
Bemisia Tabaci ◽  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Annona Muricata ◽  
Ruta Graveolens ◽  
Para Determinar ◽  
Enterolobium Cyclocarpum

La mosca blanca (Bemisia tabaci Genn.) es una especie plaga de importancia económica, ampliamente distribuida en el mundo y causante de pérdidas cuantiosas en la producción agrícola. Su combate suele basarse en aplicaciones repetitivas de insecticidas químicos, que producen contaminación ambiental y generan resistencia en las poblaciones de los insectos. Este trabajo tuvo como objetivo evaluar la actividad insecticida de nueve extractos vegetales en adultos de B. tabaci, bajo condiciones experimentales in vitro. Se realizaron bioensayos de toxicidad con los extractos etanólicos de cada planta a una concentración de 5000 mg/L, para determinar el de mejor desempeño. Las especies vegetales utilizadas fueron Enterolobium cyclocarpum (hojas y corteza), Lippia graveolens (hojas), Ruta graveolens (hojas), Adonidia merrillii (hojas y frutos), Annona muricata (semillas), Curcuma longa (raíz) y Zingiber officinale (raíz). El más tóxico fue el extracto de R. graveolens, el cual se fraccionó por cromatografía de columna con tres solventes de polaridad creciente: isopropanol: diclorometano (8:2), etanol 96% y agua. Finalmente se realizaron bioensayos con las tres particiones fitoquímicas para determinar su actividad y lograr una aproximación al tipo de compuestos responsables de la actividad tóxica. La fracción menos polar (isopropanol: diclorometano [8:2]) fue la que ocasionó la mayor mortalidad. La investigación buscó generar información para el desarrollo de métodos de combate alternativos contra la plaga en estudio, teniendo como presupuesto que los extractos vegetales son una opción promisoria para el desarrollo de bioinsecticidas más seguros para el medio ambiente y la salud humana.

scholarly journals The Effect of Allium Sativum, Curcuma Longa and Zingiber Officinale Extract on Carcinoembryonic Antigen (CEA) Levels of Breast Cancer Patients

2021 ◽  
Vol 8 (10) ◽  
pp. 391-395
Author(s):  
M. Rivandio Artianda Simatupang ◽  
Dairion Gatot ◽  
Andri Iskandar Mardia
Keyword(s):  
Breast Cancer ◽  
Allium Sativum ◽  
Curcuma Longa ◽  
Tumor Development ◽  
Zingiber Officinale ◽  
Wilcoxon Test ◽  
Breast Cancer Patients ◽  
Open Label ◽  
Anti Cancer ◽  
Before And After

Introduction: Breast cancer is global problem and commonly in women. Tumor markers can assess tumor progression and response therapy. CEA is used as diagnostic, progression and response therapy. The treatment aims to suppress tumor development. Traditional medicine is considered beneficial and has minimal effect in suppressing tumor. Recent study, extracts of Allium sativum, Curcuma longa and Zingiber officinale consider useful as anti-cancer. However, no studies that discuss combined extraction Allium sativum, Curcuma longa and Zingiber of CEA levels. Method: Open label clinical trial with one group pretest posttest design , held on June 28, 2021 – July 18, 2021, was conducted at USU Hospital and the population was breast cancer survivor community in Medan. Samples were taken by consecutive sampling. Those who met inclusion and exclusion criteria will be measured for CEA before and after administration of extract Allium sativum, Curcuma longa and Zingiber officinale with dose 500 mg twice a day for 28 days. T test or wilcoxon test was used to measure comparison and analyzed with SPSS version 22th. Results: 21 subjects who participated, only 20 subjects were analyzed with mean age of 52.7 years, majority stage III A or IIIB (30%). Median CEA before intervention 2.05 (0.70-12.20) g/mL and after intervention of 2.7 (0.8-12.40) g/mL, increasing value and not statistically significant with p>0.05 ( p=0,238).Conclusion: Median CEA value increased before and after intervention and not statistically significant. Keywords: Breast Cancer, CEA, Allium sativum, Curcuma longa and Zingiber officinale.

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