scholarly journals Evaluation of anti-dermatophytic activity of medicinal plants derived products

2020 ◽  
Vol 7 (1) ◽  
pp. 28
Author(s):  
Anu Gupta ◽  
Alisha . ◽  
Sandeep Kaur ◽  
Prabhjot Kaur Gill
Keyword(s):  
Medicinal Plants ◽  
Azadirachta Indica ◽  
Allium Sativum ◽  
Curcuma Longa ◽  
Cocos Nucifera ◽  
Zingiber Officinale ◽  
Melaleuca Alternifolia ◽  
Keratinized Tissue ◽  
Dermatophyte Species ◽  
Citrus Limonum

<p class="abstract"><strong>Background: </strong>Dermatophytes are a group of closely related fungi which are able to invade the keratinized tissue skin, hair and nail. In this study different medicinal plants like <em>Melaleuca alternifolia, Zingiber officinale, Allium sativum, Azadirachta indica, Citrus limonum, Curcuma longa, Cocos nucifera</em> were used as antifungal agent against different dermatophyte species.</p><p class="abstract"><strong>Methods: </strong>A hospital-based study consisting of 320 patients clinically diagnosed having dermatophytic infection who reported to the Dermatology outpatient department (OPD), Adesh medical college, Bathinda was conducted for the period of 2 years. Socio-demographic and clinical information was collected and sample was taken from the edge of infected area which was then collected in 2 ml of Eppendorf. Extracts of medicinal plants were then explored against dermatophyte. The data was evaluated using appropriate statistical method.</p><p class="abstract"><strong>Results: </strong>All dermatophyte species were found sensitive for <em>Melaleuca alternifolia, Zingiber officinale and Allium sativum</em>. These medicinal plants showed very good results as antifungal against dermatophytes while <em>Azadirachta indica </em>and <em>Citrus limonum </em>were moderate sensitive and <em>Curcuma longa </em>and <em>Cocos nucifera </em>did not show any zone of inhibition around the well.</p><p class="abstract"><strong>Conclusions: </strong>This research provides a scientific validation for the use of these medicinal plants in the treatment of dermatophytic infection and could be used in future for dermatophytic infection and other skin infection.</p>

scholarly journals Natural Products as Sources of Antimalarial Drugs: Ethnobotanical and Ethnopharmacological Studies

Scientifica ◽  
2020 ◽  
Vol 2020 ◽  
pp. 1-22
Author(s):  
Oluwole Solomon Oladeji ◽  
Abimbola Peter Oluyori ◽  
Deborah Temitope Bankole ◽  
Tokunbo Yemisi Afolabi
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Helianthus Annuus ◽  
Azadirachta Indica ◽  
Curcuma Longa ◽  
Cocos Nucifera ◽  
Mangifera Indica ◽  
Cymbopogon Citratus ◽  
Cassia Fistula ◽  
Medicinal Species

Ethnopharmacological Relevance. Malaria is one of the lethal diseases of man, contributing to about 17 million deaths annually, leading to sociocultural, economic, and health influences. Aim of the Study. The study explores the ethnobotanical and ethnopharmacological appraisal of antimalarial plants used by people of Omu Aran, Ogbomoso, Ado Ekiti, and Sagamu communities in Nigeria. Materials and Methods. For this study, relevant information was procured from the inhabitants via a structured questionnaire to procure the general knowledge of antimalarial medicinal plants. Results and Discussion. A total of 90 interviewees (44 men and 46 women) were involved in this survey. A total of 59 medicinal species were identified, which were dispersed in 33 families (Asteraceae (6), Apocynaceae (5), Anacardiaceae, Annonaceae, Fabaceae, Malvaceae, Meliaceae, Poaceae, and Rubiaceae (3 each), Phyllanthaceae (2)) totaling 49% of the cited species. The most cited plants are Azadirachta indica (42), Mangifera indica (38), Carica papaya (28), Cymbopogon citratus (27), Cassia fistula (15), Morinda lucida (14), Anacardium occidentale and Vernonia amygdalina (13 each), Helianthus annuus (11), Enantia chlorantha (10), and Moringa oleifera (9) A total of 105 citations were recorded for the plant parts used (leaf (46), bark (17), fruits (9), root (9), latex (11), stem (11), and inflorescence (2)) while decoction (59%), maceration (25%), infusion (9%), and exudation (7%) were the methods of preparation. Use Values (UVs) of 0.47 to 0.11 were recorded for the frequently used antimalarial plants. The Efficiency Levels (ELs) of 11 different medicinal plants stated by the respondents were Azadirachta indica, Cassia fistula and Morinda lucida (12), Chromolaena odorata (10), Mangifera indica, Enantia chlorantha and Helianthus annuus (8), Cymbopogon citratus (7), Gossypium arboretum (4), Landolphia dulcis (3), and Aloe vera (2) Cocos nucifera, Curcuma longa, Forkia biglobosa, and Musa acuminate are mentioned for the first time in the study area with little or no reported antiplasmodial activities. Conclusion. The study appraised the commonly used antimalarial plants in the study areas. Therefore, commitment to scientifically explore the bioactive compounds, antimalarial potential and toxicological profile of these plants is inevitable as they could lead to novel natural products for effective malaria therapy.

scholarly journals Review of Antiviral Medicinal Plants used in Taraba State Nigeria: A Possible Source for COVID-19 Drug Discovery

2020 ◽  
Vol 1 (2) ◽  
pp. 1-23
Author(s):  
Cletus Anes Ukwubile ◽  
Troy Silvia Malgwi ◽  
Alexander Ezekiel Angyu ◽  
Otalu Otalu ◽  
Mathias Simon Bingari
Keyword(s):  
Medicinal Plants ◽  
Allium Sativum ◽  
Viral Infections ◽  
Curcuma Longa ◽  
Antiviral Agents ◽  
Zingiber Officinale ◽  
Human Influenza Virus ◽  
Infectious Bronchitis ◽  
The Usa ◽  
Ocimum Tenuiflorum

Purpose: Coronavirus also known as COVID-19 is a viral infection that has been tagged as the greatest pandemic since the existence of humans by the WHO, resulting in the deaths of thousands of people globally; with the USA one of the highest. The full biology of the virus is yet to be known. This study reviews sixteen natural antiviral plants used in Taraba State to manage viral infections locally. Subjects and Methods: Sixteen medicinal plants popularly used as antiviral agents in Taraba State, Nigeria were surveyed based on a field-trip experience with herbal medicine practitioners in the three zones of the state. Plants that were in both zones were counted as the same. The plants that are majorly used for various viral infections are Allium sativum, Zingiber officinale, Camellia sinensis, Hibiscus sabdariffa, Cirus lemon, Azardirachta indica, Ocimum tenuiflorum, Curcuma longa, Haematostaphis barteri, Olea europaea, Melastomastrum capitatum, Astragalus canadensis, Carissa edulis, Spondias venulosa, Vitellaria paradoxa, and Euphorbia hirta. Results: Of the sixteen plants, ten have been reported to have antiviral properties against at least one of these viruses avian or bird flu, human influenza virus, infectious bronchitis virus (a type of coronavirus), herpes virus, hepatitis C virus and HIV. Conclusion: The study revealed that further research on these antiviral plants used traditionally might pave the way for the discovery of potent antiviral drugs against COVID-19.

scholarly journals Ethnopharmacological Assessment of Medicinal Plants Used against Livestock Infections by the People Living around Indus River

2014 ◽  
Vol 2014 ◽  
pp. 1-14 ◽  
Author(s):  
Sakina Mussarat ◽  
Rahila Amber ◽  
Akash Tariq ◽  
Muhammad Adnan ◽  
Naser M. AbdElsalam ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Punica Granatum ◽  
Preference Ranking ◽  
Conservation Strategies ◽  
Melia Azedarach ◽  
Withania Coagulans ◽  
The People ◽  
Preferred Species

The present study was aimed to document detailed ethnopharmacological knowledge of medicinal plants against livestock infections of an unexplored remote region of Pakistan. Semistructured questionnaires were used for data collection. Total 43 plants belonging to 26 families were found to be used in ethnoveterinary practices. Seeds (29%) were found to be the most frequent plant part used followed by leaves (22%). Ethnoveterinary recipes were mostly prepared in the form of decoction and powdering. Informant consensus factor (Fic) results revealed high consensus for gastrointestinal (0.81), mastitis (0.82), and dermatological infections (0.80).Curcuma longaranked first with highest fidelity level (FL) value (66%) followed byTrachyspermum ammithat ranked second (58%). Preference ranking (PR) results showed thatZingiber officinale,Punica granatum,Triticum aestivum,Gossypium hirsutum, andWithania coagulanswere the most preferred species for the treatment of diarrhea. Direct matrix ranking (DMR) results showed thatMorus alba,Melia azedarach,Withania coagulans,Cassia fistula,Azadirachta indica, andTamarix aphyllawere the multipurpose species of the region. We invite the attention of pharmacologists and chemists for further exploration of plants having high Fic, FL, and PR values in the present study. Conservation strategies should be adopted for the protection of multipurpose plant species.

scholarly journals Medicinal Plant by Batak Toba Medicinal plants used by the Batak Toba Tribe in Peadundung Village, North Sumatra, Indonesia

2019 ◽  
Vol 20 (2) ◽  
pp. 510-525 ◽  
Author(s):  
MARINA SILALAHI ◽  
NISYAWATI NISYAWATI ◽  
DINGSE PANDIANGAN
Keyword(s):  
Medicinal Plants ◽  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Single Species ◽  
Psidium Guajava ◽  
Piper Betle ◽  
Structured Interviews ◽  
Medicinal Species ◽  
Eurycoma Longifolia ◽  
North Sumatra

Abstract. Silalahi M, Nisyawati, Pandiangan D. 2019. Medicinal plants used by the Batak Toba Tribe in Peadundung Village, North Sumatra, Indonesia. Biodiversitas 20: 510-525. Research of the medicinal plants by the Toba Batak ethnic has limited, even though the globalization and modernization resulted to degradation of the local knowledge. The objectives of this study were (i) documentation of medicinal plants used in the traditional therapies by the Batak Toba tribe of Peadundung Village, North Sumatra, Indonesia, and (ii) analysing the data by quantitative ethnobotanical tools such as use value (UV), cultural significance index (CSI), relative frequency of citation (RCF) and informant consensus factor (ICF) to determine the cultural importance of medicinal plants in order to develop a tool for their conservation. Semi-structured interviews with 41 identified respondents was the methodology employed for qualitative data collection. A total of 149 medicinal species of plants, belonging to 131 genera and 55 families, were recorded in the study which are used in the treatment of 21 categories of ailments. Plants with the highest UV were Eurycoma longifolia (UV=3.44), Curcuma longa (UV=2.67) and Zingiber officinale (UV=2.60). Eight species, namely Curcuma longa, Eurycoma longifolia, Allium cepa, Psidium guajava, Aleurites moluccanus, Piper betle, Citrus hystrix and Uncaria gambir were found to be having the highest RCF value of 1.00. Eurycoma longifolia (CSI=126), Curcuma longa (CSI=112) and Zingiber officinale (CSI = 105) emerged as the culturally most significant medicinal plants. Thrush and aphrodisiac use categories received the highest ICF of 1.00 each because the informants agreed of using only a single species for each of these categories. Eurycoma longifolia was used as an aphrodisiac whereas Averrhoa carambola was used against thrush. All these important and significant plants suffer the greatest harvesting pressure, hence their conservation should be given priority.

Plantes médicinales utilisées contre le cancer du sein par la population d’Algérie de l’Est

2021 ◽  
Author(s):  
K. Ounaissia ◽  
R. Bechiri ◽  
M. Snani ◽  
L. Naoun
Keyword(s):  
Nous Avons ◽  
Cancer Du Sein ◽  
Allium Sativum ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Plantes Médicinales ◽  
Annona Muricata ◽  
Berberis Vulgaris ◽  
Étude Ethnobotanique

Une étude ethnobotanique des plantes médicinales utilisées traditionnellement dans le traitement du cancer du sein a été menée en 2018–2019 auprès des patients du service de radiothérapie, « centre anticancer, CAC », Annaba, Algérie. Cette étude a permis de réunir toutes les informations concernant l’usage des plantes médicinales pratiqué par les malades. L’analyse des résultats, obtenus à partir de fiches questionnaires, a permis de recenser 35 espèces végétales réparties dans 27 familles botaniques, avec une représentation importante des espèces suivantes : Nigella sativa L. (12 citations), Curcuma longa L., Allium sativum L., Berberis vulgaris L., Annona muricata L., Ephedra sp (neuf citations), suivies par le Zingiber officinale Roscoe (huit citations), le reste des espèces ont une fréquence de citation comprise entre une et sept. Nous avons noté aussi que parmi les organes des plantes, le feuillage constitue la partie la plus utilisée, avec un pourcentage de 20 %. Toutes ces informations constituent une ébauche importante pour réaliser des recherches expérimentales ultérieures dans le but de déterminer les principes actifs et leurs mécanismes d’action sur le cancer.

scholarly journals Preclinical Antihyperlipidemic Effect of Herbalism against Lipid Elevating Agents: A Review

2020 ◽  
Vol 13 (4) ◽  
pp. 1695-1707
Author(s):  
Bushra Ansari ◽  
Monika Singh ◽  
Shalini Sharma ◽  
Bushra Choudhary ◽  
Mohseen Mohseen
Keyword(s):  
Medicinal Plants ◽  
Curcuma Longa ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Zingiber Officinale ◽  
Poloxamer 407 ◽  
Low Density ◽  
Garcinia Cambogia

Abnormal increase in the level of more than any one of the lipoproteins such as triglycerides, cholesterol, LDL or VLDL in the bloodstream can be defined as hyperlipidemia. It is the greatest world is often overused so, use “the most significant” instead of the greatestrisk factor of coronary heart attack and stroke.This review emphasizes on some herbal medicinal plants with their extracts, including Glycyrrhiza glabra,Legenaria siceraria,Medicago sativa,Curcuma longa,Curatella americana, Glycine max, Hibisus rosa-sinesis, Hibisus sabdariffa, Cinnamomum tamala, Withania somnifera, Cassia auriculata, Cynaras scolymus, Eugenia jambolana, Adenanthera pavonia, Garcinia cambogia, Terminalia chebula, Ixora coccinea, Carica papaya, Lycimum barbarum, Bauhinia purpurea, Syzygium alternifolium, Vitex negundo, Piper longa, Moringa oleifera, Zingiber officinale, Trigonella foenum graecum, Carum carvi, Gloriosasuperba, Ficus infectoria, Ficus glomerata for anti-hyperlipidemic potential. Decrease in the levels of these lipoproteins like, triglycerides (TG), Total cholesterol (TC), Very low density lipoprotein (VLDL) and low-density lipoprotein (LDL)includes some mechanisms actions of these medicinal plants observed in triton-x, cholesterol, high fat diet, Poloxamer-407, Dexamethasone and alloxan-induced in-vivo and in-vitro models. Accordingly, this review provides numerous evidenceswhichindicatethat these medicinal plants can be usedfor treating and preventinghyperlipidemia and related complications.

scholarly journals Ten commonly available medicinal plants in Malaysia used for cosmetic formulations – A review

2020 ◽  
Vol 11 (2) ◽  
pp. 1716-1728
Author(s):  
Siti Nurul Najiha Othman ◽  
Pei Teng Lum ◽  
Aina Akmal Mohd Noor ◽  
Nurul Azima Mazlan ◽  
Puteri Zarith Sofea Yusri ◽  
...  
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Biological Effects ◽  
Curcuma Longa ◽  
Cocos Nucifera ◽  
Aloe Vera ◽  
Lawsonia Inermis ◽  
Garcinia Mangostana ◽  
Herbal Products ◽  
Cosmetic Formulations

Malaysia is rich in natural and herbal resources which have the potential to be used as traditional medicine as well as cosmetics. These plant sources are used by the folklore to help in enriching their beauty. Leaves, fruits, flowers and roots of medicinal plants in Malaysia are used in cosmetic formulations to get different biological effects. Health issues with particular reference to skin issues, such as acne, dry skin, dull skin and alopecia can be alleviated by using these plants. Since time immemorial, herbal products have been used in maintaining and enhancing physical appearance of humans. Herbal cosmetics have growing demand in the world market and is an invaluable gift of nature. This review is about ten commonly available medicinal plants in Malaysia used in the cosmetic formulations which includes Aloe vera, Curcuma longa, Cocos nucifera, Cucumis sativus, Melaleuca alternifolia, Punica granatum, Garcinia mangostana, Carica papaya, Lawsonia inermis and Hibiscus rosasinensis. These are the ten plants that are commonly used traditionally in treating many skin conditions and hair problems. Different parts of the plant may produce different beneficial effects to the consumers. Using the herbal and natural ingredients in cosmetics alleviates the side effects almost to nil. This is predominantly lower than the side effects caused by synthetic cosmetics.

Efficacy of Allium Sativum, Curcuma Longa and Zingiber Officinale Extract on Serum Vasculoendothelial Growth Factors Levels of Breast Cancer Patients

2021 ◽  
Vol 8 (10) ◽  
pp. 396-401
Author(s):  
Michael Yang ◽  
Dairion Gatot ◽  
Andri Iskandar Mardia
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Allium Sativum ◽  
Complete Blood Count ◽  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Serum Levels ◽  
Breast Cancer Patients ◽  
Open Label ◽  
Before And After

ntroduction: Breast cancer requires high nutrition, oxygen and metabolism where VEGF-triggered angiogenesis is needed. VEGF is triggered via the HIF-1 pathway and also via the NF-Kappa B pathway. VEGF is associated with tumor growth and metastasis. Some plant extracts have anti-angiogenesis effects such as Curcuma longa, Allium sativum and Zingiber officinale. Objective: To determine serum levels of SGOT, SGPT, ureum, creatinine, albumin and VEGF before and after administration of Curcuma longa, Allium sativum and Zingiber officinale extracts Method: An open label clinical trial study with a one group pretest posttest design involving 21 patients from breast cancer community in Medan collected by consecutive sampling from June – July 2021 in USU hospital where these patients met the inclusion criteria. All patients were tested for complete blood count, urea, creatinine, SGOT, SGPT, albumin, serum VEGF before and after being given a combination extract of Curcuma longa 150 mg, Allium sativum 200 mg and Zingiber officinale 150 mg twice daily for 28 days. Statistical analysis was performed by paired analytical T test or Wilcoxon. Results: The study involved 20 subjects. From the examination of kidney function obtained results before and after the administration of a combination extract VEGF results before and after the administration of the combination (1110(760-7893) μg / ml vs. 864 (532-5650 μg / ml, p = 0.001). Conclusion: VEGF serum breast cancer patients had a significant reduction after being given a combination of extracts of Allium sativum, Curcuma longa and Zingber officinale. Keywords: VEGF, Allium sativum, Curcuma longa, Zingiber officinale.

STUDY OF THE EFFECT OF MEDICINAL PLANTS EXTRACTS ON THE INFECTED BLOOD

2017 ◽  
Vol 5 (1) ◽  
pp. 21
Author(s):  
Supriya Kate ◽  
Harsha M Chatrath
Keyword(s):  
Medicinal Plants ◽  
Boiling Point ◽  
Allium Sativum ◽  
Carica Papaya ◽  
Curcuma Longa ◽  
Solution Temperature ◽  
Critical Solution Temperature ◽  
Infected Blood ◽  
Being There ◽  
The Comparative Study

Medicinal plants are used for treating and preventing the specific disease that affects the human being. There are several species of medicinal plants available in nature; amongst those researchers selected Basil, Zingiber, Azadirachtaindica, Curcuma longa, Carica Papaya, Allium sativum for research purpose. Natural compounds have been isolated from various parts such as leaves, fruits, stem, roots, and seeds of these plants. The present paper is the comparative study of variation in the physical properties like pH, critical solution temperature, and boiling point, etc. of these medicinal plants, individually, in combination ratios and also with the infected blood doped samples.

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