scholarly journals Evaluation of the, in vitro, photoprotetive capacity of Moringa oleifera oil for its use in sunscreen formulation

2021 ◽  
Vol 10 (2) ◽  
pp. 14-20
Author(s):  
Viviane Martins rebello Dos santos ◽  
Gabriela Cristina Ferreira Mota ◽  
Kamila Campos ◽  
Lucas Sousa ◽  
Tatiane Amparo ◽  
...  
Keyword(s):  
Moringa Oleifera ◽  
Human Fibroblasts ◽  
Cytotoxic Potential ◽  
Protection Factor ◽  
Increasing Demand ◽  
Moringa Oleifera Oil ◽  
Moringa Oil ◽  
Sunscreen Formulation ◽  
Moringa Oleifera Lam

Moringa oleifera Lam is an Indian plant with applications in the agricultural and medical fields. The assets development capable of increasing the efficiency of sunscreens, mainly those of plant origin, due to their natural benefits, represents an increasing demand for cosmetology. The present study aims to identify by CG-MS the constituents of the most active oil and to evaluate the photoprotective capacity of Moringa oil, and its action in sunscreen formulations. Extracts of the oils from the Moringa seeds were evaluated for the Sun Protection Factor (SPF) observing the highest result for the dichloromethane extract. This extract showed low cytotoxic potential for human fibroblasts and it was incorporated into a sunscreen. The extract increased the SPF of the sunscreen and its effect may be related to fatty acids identified by GC-MS. The results showed the benefit of Moringa oil as a vegetable active in the sunscreen formulations by increasing the SPF of sunscreens in a natural and sustainable way.

Bioaccessibility, antioxidant activity and modulation effect on gut microbiota of bioactive compounds from Moringa oleifera Lam. leaves during digestion and fermentation in vitro

2019 ◽  
Vol 10 (8) ◽  
pp. 5070-5079 ◽  
Author(s):  
Zuman Dou ◽  
Chun Chen ◽  
Xiong Fu
Keyword(s):  
Antioxidant Activity ◽  
Gut Microbiota ◽  
Bioactive Compounds ◽  
Moringa Oleifera ◽  
Modulation Effect ◽  
Gastrointestinal Digestion ◽  
Colonic Fermentation ◽  
Moringa Oleifera Lam

This study aims to investigate the bioaccessibility, bioactivity and gut microbiota modulation effect of Moringa oleifera Lam. leaves after in vitro gastrointestinal digestion and colonic fermentation.

The in vitro and ex vivo antioxidant properties, hypolipidaemic and antiatherosclerotic activities of water extract of Moringa oleifera Lam. leaves

2008 ◽  
Vol 116 (3) ◽  
pp. 439-446 ◽  
Author(s):  
Pilaipark Chumark ◽  
Panya Khunawat ◽  
Yupin Sanvarinda ◽  
Srichan Phornchirasilp ◽  
Noppawan Phumala Morales ◽  
...  
Keyword(s):  
Moringa Oleifera ◽  
Ex Vivo ◽  
Antioxidant Properties ◽  
Water Extract ◽  
Moringa Oleifera Lam

Moringa Oleifera Oil Modulates Rumen Microflora to Mediate In Vitro Fermentation Kinetics and Methanogenesis in Total Mix Rations

2020 ◽  
Vol 77 (7) ◽  
pp. 1271-1282 ◽  
Author(s):  
Hossam M. Ebeid ◽  
Li Mengwei ◽  
Ahmed E. Kholif ◽  
Faiz-ul Hassan ◽  
Peng Lijuan ◽  
...  
Keyword(s):  
Moringa Oleifera ◽  
In Vitro Fermentation ◽  
Fermentation Kinetics ◽  
Rumen Microflora ◽  
Moringa Oleifera Oil

scholarly journals In vitro Photoprotective Evaluation and Development of Novel Nanoemulsion with Chromone Derivative

2021 ◽  
Author(s):  
Amanda Antunes ◽  
Ana Paula Gouveia ◽  
Gabriela Diogo ◽  
Jason Taylor ◽  
Lucas Sousa ◽  
...  
Keyword(s):  
High Resolution Mass Spectrometry ◽  
Human Fibroblasts ◽  
Protection Factor ◽  
Chromone Derivatives ◽  
In Vivo Assays ◽  
Sulforhodamine B ◽  
Sulforhodamine B Assay ◽  
Excellent Stability

Chromone derivatives exhibiting high absorbance values in the UVA/UVB region were synthesized, and their photoprotective properties were evaluated. Chromones were prepared according to known literature procedures and characterized by high resolution mass spectrometry, infrared (IR) and nuclear magnetic resonance (NMR) spectroscopy. The in vitro solar protection factor (SPF) was determined by the Mansur method and cytotoxicity was evaluated using the sulforhodamine B assay. Two of the chromones synthesized demonstrated suitable SPF values and displayed no cytotoxic effect towards MRC-5 human fibroblasts at the tested concentrations, indicating great potential for future in vivo assays and clinical trials. Finally, the lead compound was incorporated into a nanoemulsion. Nanoemulsions showed high droplet size homogeneity and excellent stability. Chromones bearing methoxy substituents were found to be the most promising compounds with ideal photoprotective properties desirable for utilization and incorporation in sunscreen formulations.

scholarly journals Moringin, A Stable Isothiocyanate from Moringa oleifera, Activates the Somatosensory and Pain Receptor TRPA1 Channel In Vitro

Molecules ◽  
2020 ◽  
Vol 25 (4) ◽  
pp. 976
Author(s):  
Gigliola Borgonovo ◽  
Luciano De Petrocellis ◽  
Aniello Schiano Moriello ◽  
Simona Bertoli ◽  
Alessandro Leone ◽  
...  
Keyword(s):  
Ion Channel ◽  
Moringa Oleifera ◽  
Food Supplement ◽  
In Vitro Assays ◽  
Neurogenic Pain ◽  
Natural Origin ◽  
Traditional Medicines ◽  
Tropical Plant ◽  
Moringa Oleifera Lam

Moringa oleifera Lam. is a tropical plant widely used in traditional medicines and as a food supplement. It is characterized by the presence of glucosinolates and isothiocyanates; the stable isothiocyanate 4-[(α-l-rhamnosyloxy)benzyl]isothiocyanate (moringin) has been widely studied for its bioactivity as hypoglycemic, antimicrobial, anticancer and in particular for its involvement in nociception and neurogenic pain. Moringa extracts and pure moringin were submitted to in vitro assays with the somatosensory TRPA1 ion channel, proving that moringin is a potent and effective agonist of this receptor involved in nociceptive function and pain states. Moringin do not activate or activates very weakly the vanilloids somatosensory channels TRPV1,2,3 and 4, and the melastatin cooling receptor TRPM8. The comparison of moringin’s activity with other known agonists of natural origin is also discussed.

Leucaena leucocephala (Lam) de Wit and Moringa oleífera Lam: Especies con alto valor proteico para la liberación de péptidos bioactivos

2019 ◽  
Vol 12 (11) ◽  
Author(s):  
E. B. León-Espinosa ◽  
R.G. Cruz Monterrosa ◽  
M. Díaz Ramírez ◽  
J. Jiménez Guzmán ◽  
M. García Garibay ◽  
...  
Keyword(s):  
Leucaena Leucocephala ◽  
Moringa Oleifera ◽  
Para Determinar ◽  
Moringa Oleifera Lam

Leucaena y Moringa son leguminosas con un alto valor nutricional (proteínas), por lo que pueden ser utilizadas como fuente de proteína para la producción de concentrados, aislados o hidrolizados proteicos. Estos materiales, ricos en proteína, pueden además ser sustrato para la producción de péptidos bioactivos, que son secuencias de aminoácidos presentes en las proteínas que al ser liberados por digestión gastrointestinal o proteólisis in vitro con diferentes enzimas, presentan algunas actividades biológicas, como la antioxidante y anticancerígena, además de propiedades funcionales. Los diferentes estudios realizados de estas semillas hasta el momento proveen información que sugiere que pueden dar lugar a fragmentos susceptibles para la liberación de pépticos con diversas actividades, lo que podría ser una estrategia adecuada para la producción de péptidos bioactivos con actividad bio-funcional. Sin embargo, se requiere de mayor investigación sobre las características de los fragmentos liberados para determinar los mecanismos y propiedades de las secuencias responsables de las diversas actividades.

Sign in / Sign up

Export Citation Format

Share Document