scholarly journals Eclampsia An Obstetric Disaster

2004 ◽  
Vol 43 (151) ◽  
pp. 49-55
Author(s):  
P Pradhan
Keyword(s):  
Developing Countries ◽  
Perinatal Mortality ◽  
Magnesium Sulphate ◽  
Caesarean Section Rate ◽  
Cortical Blindness ◽  
Antihypertensive Drug Therapy ◽  
Routine Practice ◽  
Electrolyte Balance ◽  
Mortality And Morbidity ◽  
In Pregnancy

Eclampsia has been graded as fatal and dreadful disease even before Christ and is the important cause ofmaternal and perinatal mortality in developed and developing countries. Severe morbidity associated witheclampsia include placental abruptio, cerebral haemorrhage, cortical blindness, renal failure, disseminatedintravascular coagulopathy, pulmonary oedema, psychosis and growth retardation and preterm or both.Present management of eclampsia aims to stop the convulsions, its recurrences, control of blood pressureand correct fluid and electrolyte balance and delivery of the baby. There have been great controversiesabout the best anticonvulsants to use. The randomised trials comparing magnesium sulphate with diazepamor phenytoin showed greater efficacy of magnesium sulphate in the control and prevention of recurrence offits. Perinatal mortality is also better with magnesium sulphate. Intramuscular injection is painful andlocal abscess formation at the site of injection is possible. Control of dose is better with intravenous routetherefore preferred. Magnesium sulphate should be continued for 24 hours after the delivery or after thelast fit. Antihypertensive drug therapy is now a routine practice in the management of pre-eclampsia andeclampsia. Methyl dopa, Lobetelol, Nefedipine are well tried in pregnancy and safe in pregnancy. However,hydralazine intravenous is good for quick and smooth control of blood pressure. Termination of pregnancyhas been an important part of the management of eclampsia. Studies have shown that maternal outcomesseems better with caesarean delivery compared to vaginal delivery. The caesarean section rate is high at26.3-80.4% in different studies. Recently maternal mortality and morbidity has been greatly improvedeven in developing countries by better control of fits by magnesium sulphate and caring them in intensivecare unit.Key Words: Eclampsia, Anticonvulsants, Antihypertensives, Delivery.

scholarly journals A comparative study of low dose magnesium sulphate therapy with Pritchard’s regime in management of Eclampsia

2019 ◽  
Vol 8 (10) ◽  
pp. 3907
Author(s):  
Vijay M. Kansara ◽  
Payal Sureshkumar Patel ◽  
Ajesh N. Desai
Keyword(s):  
Perinatal Mortality ◽  
Magnesium Sulphate ◽  
Low Dose ◽  
Fetal Outcome ◽  
Control Group ◽  
Average Weight ◽  
Indian Women ◽  
Mortality And Morbidity ◽  
Labour Room ◽  
And Control

Background: Eclampsia is one of the most common causes of maternal and perinatal mortality and morbidity in India. Amongst the principles of management of eclampsia, the first is the control of convulsions. Magnesium sulphate is the main stay of treatment in eclampsia and imminent eclampsia. Average weight of Indian women is less than the western women due to which lower dose of magnesium sulphate can be used.  The aim of the study was to compare the efficacy of low dose magnesium sulphate regimen with standard Pritchard regimen in control of eclampsia.Methods: The study was carried out at emergency labour room, GMERS Sola Civil Hospital Ahmedabad. 120 patients of eclampsia were divided randomly into study group (n=60) receiving low dose MgSO4 and control group (n=60) receiving Pritchard regimen. The recurrence of convulsion, toxicity of MgSO4 and maternal and fetal outcome was studied.Results: It was observed that with low dose MgSO4 regime, convulsions were controlled in 91.7% of the cases. With standard Pritchard’s regime convulsions were controlled in 95% of patients. The maternal and perinatal mortality and morbidity were comparable in both groups.Conclusions: Low dose magnesium sulphate therapy is as effective as Pritchard’s regime for controlling convulsions in eclampsia and can be safely given in Indian women. 

scholarly journals Diabetic ketoacidosis in pregnancy

2018 ◽  
Vol 7 (7) ◽  
pp. 2945
Author(s):  
Rosália S. Coutada ◽  
Soraia S. Cunha ◽  
Elisabete S. Gonçalves ◽  
Ana P. Gama ◽  
João P. Silva ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Pregnant Woman ◽  
Diabetic Ketoacidosis ◽  
Perinatal Mortality ◽  
Aggressive Treatment ◽  
Mortality And Morbidity ◽  
Threatening Condition ◽  
Life Threatening ◽  
In Pregnancy

Diabetic ketoacidosis in pregnancy is a rare but potential life-threatening condition for the mother and the fetus. It tends to occur latter in pregnancy and is more common in patients with pregestational diabetes. Obstetricians should be aware of the events that can trigger diabetic ketoacidosis in pregnancy. Prompt recognition and aggressive treatment of this condition are essential in order to reduce perinatal mortality and morbidity. The authors present a case of a pregnant woman with type 1 diabetes with a poor surveillance of pregnancy and noncompliance to treatment that develops severe diabetic ketoacidosis at 34 weeks of gestation.

scholarly journals Characteristics shifting of heart disease in pregnancy: A report from low middle-income country

2021 ◽  
Author(s):  
Cyntia Puspa Pitaloka ◽  
Absa Secka ◽  
Ernawati Ernawati ◽  
Agus Sulistyono ◽  
Hermanto Tri Juwono ◽  
...  
Keyword(s):  
Developing Countries ◽  
Heart Disease ◽  
Pregnant Women ◽  
Cardiac Disease ◽  
Cardiac Complications ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
Acquired Heart Disease ◽  
Heart Disease In Pregnancy ◽  
In Pregnancy

Background: Heart disease in pregnancy is one of the leading causes of maternal mortality and morbidity in developing countries. However, the characteristics of the disease vary between countries and regions. This study aimed to present the characteristics of pregnant women with heart disease in an economically advantageous region of a developing country.Design and methods: A cross-sectional study was conducted using data from the Weekly Report of Obstetrics and Gynaecology Department to assess pregnant women with heart disease characteristics and pregnancy outcomes. A total sample of 69 pregnant women with heart disease regarding their gestational age was included in the study. Variables observed were maternal characteristics, heart disease's clinical parameters, and maternal and neonatal outcomes. Chi-square test was used to examine the different characteristics of congenital and acquired heart disease groups.Results: The prevalence of cardiac disease in pregnancy was 5.19%. Fifty-three point six percent of pregnant women with heart disease were suffered from congenital heart disease (CHD), while 46.4% were acquired heart disease (AHD). Most labor methods were Cesarean delivery, and 69.6% of women experienced cardiac complications. Maternal death was reported in 8.69% of cases. Four cases were CHD complicated by pulmonary hypertension, which leads to Eisenmenger syndrome. Two other cases were AHD complicated by Peripartum Cardiomyopathies. Although statistically insignificant, complications are more common in the AHD group than CHD.Conclusion: Cardiac disease prevalence in pregnancy is considered high, with CHD as the most common case, which significantly differs from other developing countries.

scholarly journals Jaundice in Pregnancy: A Clinical Study at Fatima Memorial System

2015 ◽  
Vol 7 (1) ◽  
pp. 22-25
Author(s):  
Afshaan Ambreen ◽  
Farhatulain Ahmed ◽  
Attia Sheikh ◽  
Muhammad Rashid Ayub ◽  
Numeera Faryad ◽  
...  
Keyword(s):  
Clinical Study ◽  
Viral Hepatitis ◽  
Perinatal Mortality ◽  
South Asian ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Mortality And Morbidity ◽  
Younger Age ◽  
In Pregnancy

ABSTRACT Objective The objective of the study is to find the effect of jaundice during pregnancy on fetomaternal outcome over a 10-year period at tertiary care hospital. Materials and methods An analysis of fetomaternal outcome of all case records with jaundice in pregnancy from January 2003 to December 2013 is made. Results The incidence of jaundice in our study is one in 278 pregnancies, with the disease more common in younger age group. Viral hepatitis found to be the commonest cause, HEV being the commonest with a high maternal and perinatal mortality. Obstetric cholestasis being the second most common followed by HELLP syndrome, AFLP and sepsis; Hepatorenal failure, encephalopathy, DIC and PPH were the main causes of maternal mortality. Conclusion Viral hepatitis is most prevalent cause of jaundice in pregnancy, associated with a high maternal and perinatal mortality and morbidity. How to cite this article Ambreen A, Ahmed F, Sheikh A, Ayub MR, Faryad N, Mushtaq S. Jaundice in Pregnancy: A Clinical Study at Fatima Memorial System. J South Asian Feder Obst Gynae 2015;7(1):22-25.

scholarly journals Perinatal Outcome of Premature Rupture Membrane in Pregnancy

2018 ◽  
Vol 26 (2) ◽  
pp. 135-139
Author(s):  
Housneara Begum ◽  
Marlina Roy ◽  
Nahid Reaz Shapla
Keyword(s):  
Perinatal Mortality ◽  
Perinatal Death ◽  
Correct Diagnosis ◽  
Mortality And Morbidity ◽  
Medical College ◽  
Intact Membrane ◽  
Fetal Complications ◽  
Statistical Program ◽  
Antibiotic Coverage ◽  
In Pregnancy

Objective: To find out the effect of PROM on neonatal outcome so that we can pay more attention for the correct diagnosis and management of PROM in pregnancy which can reduce the perinatal mortality and morbidity caused by PROM.Methods: One hundred PROM cases were selected maintaining appropriate inclusion & exclusion criteria from the department of obstetrics & Gynaecology of BSMMU & DMCH and one hundred controlled cases were taken from the same during the period of January 2010 to December 2010. Data were analyzed with SPSS statistical program to determine the effect of PROM on neonatal health.Results: In this study, 44% babies of PROM patients had various type of morbidity compare to 24% of patients with intact membrane. In PROM patients, perinatal mortality was 7% in this study compare to 5% with intact membrane. Causes of perinatal death in PROM was severe asphyxia (4%), RDS (5%) & neonatal sepsis (6%) mainly.Conclusion: All fetal complications were significantly higher in PROM patients who received treatment after prolonged rupture of membrane. Appropriate antibiotic coverage in appropriate time will reduce fetal morbidity.J Dhaka Medical College, Vol. 26, No.2, October, 2017, Page 135-139

scholarly journals Magnesium sulphate therapy in eclampsia and pre-eclampsia

2018 ◽  
Vol 7 (8) ◽  
pp. 3189
Author(s):  
Smriti Sagar ◽  
Neeta Natu ◽  
Nootan Chandwaskar
Keyword(s):  
Adverse Effects ◽  
Perinatal Mortality ◽  
Magnesium Sulphate ◽  
Maintenance Dose ◽  
Neonatal Outcome ◽  
Age Group ◽  
Additional Dose ◽  
Mortality And Morbidity ◽  
Z Value ◽  
Premonitory Symptoms

Background: Maternal and perinatal mortality and morbidity remains high during pregnancy in the presence of eclampsia, it can have severe adverse effects on mother and the fetus. So, its management should be a top priority. The objective of the present research was to study the effect of magnesium sulphate in control of imminent eclampsia and eclampsia.Methods: 19 cases of eclampsia and 185 cases of imminent eclampsia were treated with standardized magnesium sulphate. The outcome measures in terms of recurrence of convulsions, maternal and neonatal outcome, etc. were seen.Results: Most common age group in both the groups were 21-30 years (i.e. 78.9% with eclampsia and 75.7% with imminent eclampsia). In both the groups, majority of the women were primigravidae. In eclampsia group, 9 (47.4%) women had 1 episode of convulsion, 8 (42.1%) women had two episodes of convulsions, 1 (5.3%) women each had 3 and 4 episodes of convulsions, while there were no convulsions in imminent eclampsia women (‘t’ value = 28.558, df=202, p=0.000). Vomiting and headache (94.7%) were the most common premonitory symptoms in eclampsia group, followed by edema in 68.4% women, while in imminent eclampsia 64.9% women had headache, 57.8% women had edema and 43.2% had vomiting. Recurrence of convulsions were seen in 4 (21.1%) women of the eclampsia group even after giving maintenance dose and additional dose of magnesium sulphate. 1 (5.3%) death was seen in eclampsia group and none in the imminent eclampsia group. Neonatal mortality in eclampsia group (47.4%) was higher than imminent eclampsia group (11.7%), which was statistically significant (Z value = 3.05, p=0.002).Conclusions: Magnesium sulphate regimen was effective in control of convulsions in eclampsia and as prophylaxis in imminent eclampsia.

Critical Review of Data Analytics techniques used in the Expanded Program on Immunization (EPI)

2020 ◽  
Vol 16 ◽  
Author(s):  
Sadaf Qazi ◽  
Muhammad Usman
Keyword(s):  
Machine Learning ◽  
Developing Countries ◽  
Data Analytics ◽  
Public Health Intervention ◽  
Cold Chain ◽  
Data Repository ◽  
Quality Of Data ◽  
Mortality And Morbidity ◽  
Healthcare Facilities ◽  
Expanded Program On Immunization

Background: Immunization is a significant public health intervention to reduce child mortality and morbidity. However, its coverage, in spite of free accessibility, is still very low in developing countries. One of the primary reasons for this low coverage is the lack of analysis and proper utilization of immunization data at various healthcare facilities. Purpose: In this paper, the existing machine learning based data analytics techniques have been reviewed critically to highlight the gaps where this high potential data could be exploited in a meaningful manner. Results: It has been revealed from our review, that the existing approaches use data analytics techniques without considering the complete complexity of Expanded Program on Immunization which includes the maintenance of cold chain systems, proper distribution of vaccine and quality of data captured at various healthcare facilities. Moreover, in developing countries, there is no centralized data repository where all data related to immunization is being gathered to perform analytics at various levels of granularities. Conclusion: We believe that the existing non-centralized immunization data with the right set of machine learning and Artificial Intelligence based techniques will not only improve the vaccination coverage but will also help in predicting the future trends and patterns of its coverage at different geographical locations.

scholarly journals Impact of sex on perinatal mortality and morbidity in twins

2014 ◽  
Vol 42 (2) ◽  
Author(s):  
Emma Elsmén Steen ◽  
Karin Källén ◽  
Karel Maršál ◽  
Mikael Norman ◽  
Lena Hellström-Westas
Keyword(s):  
Perinatal Mortality ◽  
Mortality And Morbidity
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