scholarly journals Histomorphological spectrum of breast diseases

1970 ◽  
Vol 39 (136) ◽  
pp. 338-341
Author(s):  
Usha Rani Singh ◽  
A N Thakur ◽  
S P Shah ◽  
A Mishra
Keyword(s):  
Benign Lesion ◽  
Malignant Lesion ◽  
Breast Disease ◽  
Breast Diseases ◽  
Fibrocystic Disease ◽  
Duct Carcinoma ◽  
Malignant Lesions ◽  
Breast Lumps ◽  
Medical University ◽  
Breast Tissues

All breast lumps are considered to be carcinomas until proved otherwise and are acause of concern both for the patient and surgeon. The study was undertaken to knowthe histological spectrum of breast disease at B. P. Koirala Institute of Health Sciences(BPKIHS). BPKIHS is a recently started Medical University in the easternregion of Nepal. No data regarding breast diseases in this region is available as yet.152 breast tissues sent for histopathology from Jan. 96 - Dec. 98 were studied. Peakincidence of benign lesion was in 21 to 30 years and malignant lesions in 31 to 50years. No breast lesions were seen in the first decade of life. Cancer was seen in18.42% of cases. Fibroadenoma & Fibrocystic disease were the commonest benign &infiltrating duct carcinoma the commonest malignant lesion. Specimens from 10 malebreasts were received. Gynaecomastia was the commonest lesion in the males. Infiltratingduct carcinoma was seen in a 70 years male. Some uncommon breast lesionslike Syringocystadenoma & cysticercosis were also seen. In 3.28% of cases no lesionswere seen.Key Words: Breast, Fibroadenoma, Fibrocystic disease,carcinoma, Gynaecomastia.

scholarly journals Profile of benign breast disease in Kashmiri women: a prospective study

2017 ◽  
Vol 4 (6) ◽  
pp. 1973
Author(s):  
Mumtazdin Wani ◽  
Shabir Ahmad Mir ◽  
Mohammad Hanief Dar
Keyword(s):  
Prospective Study ◽  
Benign Lesion ◽  
Breast Disease ◽  
Breast Diseases ◽  
Symptom Duration ◽  
Duration Of Symptoms ◽  
Benign Breast Diseases ◽  
Predominant Symptom ◽  
Breast Lumps ◽  
The Right

Background: Though benign breast diseases are very common, not many studies have focussed on this entity. In Kashmir valley, no major study has been undertaken before, to look into the profile of the benign breast diseases in women.Methods: This prospective study was conducted in the Postgraduate Department of General Surgery of SMHS Hospital from October 2012 to September 2014. The patients with features of benign breast diseases were subjected to detailed history, clinical examination and investigations. Analysis was done using this data.Results: 80% of the benign breast lesions presented in the second and third decades of life. Mean age was 24.46 years. Most common benign breast lesion was fibroadenoma. Lump in the breast was the predominant symptom. Duration of symptoms mostly ranged from 1 to 6 months. There was a slight preponderance of lesions in the right breast. Most of lesions presented in upper outer quadrant.  81.39% of the patients had only a solitary lump.76.74% of lumps had a size of 2 to 5cm. Clinicopathological correlation in case of fibroadenoma, showed 60% sensitivity, 75% specificity, PPV=85.71% and NPV=42.85%. Cytohistological correlation in case of fibroadenoma, showed 85% sensitivity, 87.5% specificity, PPV=94.4% and NPV=70%. 38 cases (38%) were managed conservatively and 62 cases (62%) were managed surgically.Conclusions: Results grossly similar to other parts of the word were obtained. Fibroadenoma was the most common benign lesion encountered followed by fibroadenosis and breast abscess. Majority of breast lumps were painless. Conservative approach for fibroadenoma is acceptable option in the adolescents.

scholarly journals Profiles of Breast Diseases among Women Seeking for Treatment during Covid-19 Pandemic at Surgery OPD of Medical University of Bangladesh

2021 ◽  
Vol 8 (1) ◽  
pp. 3-6
Author(s):  
Bidyut Chandra Debnath ◽  
Abanti Ghosh ◽  
Abul Kalam Chowdhury ◽  
Rana Jahangir ◽  
Ferdous Alam ◽  
...  
Keyword(s):  
Breast Disease ◽  
Cross Sectional Study ◽  
Breast Diseases ◽  
Age Group ◽  
Fibrocystic Disease ◽  
Breast Lump ◽  
Cross Sectional ◽  
Study Population ◽  
The Mean ◽  
Medical University

Background: Different pathology of breast is found among the women. Objective: The purpose of the present study was to see the profiles of breast disease among women seeking for treatment during Covid-19 pandemic at the OPD of medical university of Bangladesh. Methodology: This descriptive cross-sectional study was conducted in the Department of Surgery at Bangabandhu Shiekh Mujib Medical University, Dhaka, Bangladesh from 1 April to 31 October 2020 for a period of six months. All the women who were attended at the OPD of the Department of Surgery with the different complaints of breast at any age were selected as study population. The different disease profiles were recorded in the data sheet. Result: A total number of 1625 women were recruited for this study. The mean age with standard deviation of the study population was 36.4±12.54 years. Among 1492 women the most common breast complaints was mastalgia which was 492(29.9%) cases followed by fibrocystic disease, breast lump, fibroadenoma and carcinoma breast which was 296(18.0%) cases, 202(12.3%) cases, 141(8.6%) cases and 84(5.1%) cases respectively. Similarly duct ectasia, fibroadenoma, fibrocystic disease and lipoma were also most common among the less than or equal to 45 years age group of women which were 47(94.0%) cases, 137(97.2%) cases, 269(90.9%) cases and 75(51.4%) cases respectively. Conclusion: In conclusion breast lump and fibrocystic disease are the most common diseases among the women attending during covid19 era. Journal of Current and Advance Medical Research, January 2021;8(1):3-6

scholarly journals Benign and malignant lesions of the breast: clinico-pathological perspective from a government teaching hospital in West Bengal, India

2018 ◽  
Vol 5 (11) ◽  
pp. 3460 ◽  
Author(s):  
Saurav Sarkar ◽  
Arista Lahiri ◽  
Soumyajyoti Bandyopadhyay ◽  
Snehasish Das ◽  
Tamal Chakraborty
Keyword(s):  
Ductal Carcinoma ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Benign Disease ◽  
Breast Diseases ◽  
P Value ◽  
Histopathological Diagnosis ◽  
Age Group ◽  
Peau D’Orange ◽  
Malignant Lesions

Background: While breast cancer is one of the most commonly diagnosed cancer more than half of the women develop some benign disease of breast in their lifetime. The current study was conducted to describe the clinico-pathological findings associated with breast diseases and study their relationship.Methods: A record-based cross-sectional study was conducted on the samples of breast tissue obtained by fine needle aspiration cytology (FNAC) examination. The clinical variables like age, sex, presenting complaint, involved side (right/left/both) etc. were taken from the clinical notes sent, and nature of the aspirate, histopathological diagnosis, nature of the diagnosed disease (benign/malignant), and axillary metastasis were taken as variables from pathological examination.Results: The mean age of the patients was 33.49 years (±13.24 years) with majority belonging to 20-40 years. Among the 184 specimens examined, 94.57% belonged to female patients. The most frequent presentation was with lump (95.11%). Complaint arising out of right breast (47.83%) were higher compared to left breast (40.76%). Involvement of the supero-lateral quadrant was seen in 75.54%. In 30.44% of the cases the material was bloody or blood-mixed. Majority of the patients (86.41%) were diagnosed with benign disease commonest being fibroadenoma. Ductal carcinoma was the commonest malignant lesion. Younger age group, absence of bloody discharge and absence of peau d’orange were associated with benign lesion in a statistically significant way (p-value <0.001).Conclusions: In consonance with published literature the findings suggest association of older age group with malignant lesions. Blood-mixed aspirate, peau d’orange appear to be danger signs.

scholarly journals Frequency of benign breast diseases in female patients presenting with breast lumps - a study at Sir Ganga Ram Hospital, Lahore

2016 ◽  
Vol 11 (4) ◽  
Author(s):  
Kamran Ali ◽  
Muhammad Hassan Abbas ◽  
Sadia Aslam ◽  
Muhammad Aslam ◽  
Khalid Javed Abid ◽  
...  
Keyword(s):  
Breast Imaging ◽  
Final Diagnosis ◽  
Breast Diseases ◽  
Fibrocystic Disease ◽  
Female Patients ◽  
Benign Breast Diseases ◽  
Fibrocystic Change ◽  
Breast Lumps ◽  
One Year ◽  
Age Range

Objective: To determine the frequency of benign breast diseases in female patients in our setup. Design: Prospective descriptive study. Place and duration of study: The study was carried on female patients presenting at surgical out door of Sir Ganga Ram Hospital, Lahore during one year i.e. January 2001 to January 2002. Patients and methods: Two hundred female patients presenting with breast lumps at surgical out door of Sir Ganga Ram Hospital, Lahore during one year were studied. All the patients were examined clinically with special emphasis on breast, axilla and supra clavicular fossae. Basic laboratory investigations including blood complete examination, urine complete examination and chest X -ray were done for all the patients. Breast imaging and FNAC of lumps were also done. Final diagnosis was based upon histological examination of the tissues biopsied from the lump. After collecting data, written in proforma, window SPSS software was used to analyze the results. Results: This study shows a high f requency of fibroadenoma (45%) in Pakistani females. Fibrocystic disease is second in frequency and accounts for 36% patients.8% patients had intraductal papilloma and three percent suffered from duct ectasia.5% patients had other conditions related to breast including two patients presenting with pre histological diagnosis of fibrocystic disease who turned out to be malignant after histopathology. Most of the patients had age range of 20-29 years. Conclusion: Fibroadenoma is the commonest of all benign breast diseases in Pakistani women. Fibrocystic change is the second in this regard. Benign lesions of the breast can resemble its carcinoma on clinical examination.

scholarly journals Role of triple assessment modalities in diagnosis of palpable breast lump

2018 ◽  
Vol 6 (10) ◽  
pp. 3435
Author(s):  
Ashwinkumar S. Gadhvi ◽  
Udit I. Gadhvi ◽  
Dhaval A. Bhimani ◽  
Darshil K. Rajgor
Keyword(s):  
Benign Lesion ◽  
Malignant Lesion ◽  
Breast Disease ◽  
Breast Lump ◽  
Size Number ◽  
Life Saving ◽  
Triple Assessment ◽  
Palpable Breast ◽  
Sensitivity Specificity

Background: One fourth of women suffer from breast disease in their lifetime. Carcinoma of breast is the second most common cancer in the world. Timely and accurate diagnosis of breast lump with early intervention can be life saving. There are various modalities for the diagnosis of breast lump such as USG, FNAC and Mammography, MRI etc. but none of them is perfect. There are numerous reports suggesting that if the results of clinical assessment, mammography and FNAC are all combined, the diagnostic accuracy is nearly 100%. Furthermore, these techniques also provide information about tumor size, number, extent and grade preoperatively.Methods: Study was randomized, prospective, observational and longitudinal including 100 patients, selected according to inclusion criteria.Results: The sensitivity, specificity and accuracy of triple test in present study were 98.68%, 87.5%, and 96% respectively. Out of 100, 76 patients were confirmed as having benign lesion and 24 patients having malignant lesion by histopathology examination.Conclusions: Results of triple assessment are same as the results by histopathology examination in majority of cases. It is highly accurate, can be used as a confirmatory diagnostic tool for breast lump, thus there is no need to perform diagnostic open biopsy for breast lump.

scholarly journals Pattern of Fine Needle Aspiration Cytology of Superficially Palpable Lesions: One year hospital based study

1970 ◽  
Vol 9 (2) ◽  
pp. 25-29
Author(s):  
E Piya ◽  
R Panth ◽  
S Singh
Keyword(s):  
Salivary Gland ◽  
Lymph Node ◽  
Ductal Carcinoma ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Aspiration Cytology ◽  
Chronic Sialadenitis ◽  
Wide Range ◽  
Malignant Lesions ◽  
One Year

Introduction: This is a retrospective study on fine need aspiration cytology (FNCA) of superficially palpable lesions done in Shree Birendra Hospital, Chhauni, over a period of one year from 14th April 2008 to 13th April 2009. Aim: The aim of this study was to review cytological diagnosis on superficially palpable lesions in various sites. Methods: A total of 323 cytological diagnoses of palpable lumps performed in one year by pathologists were retrieved. Sites of FNA and diagnoses were analyzed and correlated with age and sex of the patients. Results:This study has included 323 FNACs. Lymph node was the most common site for FNAC (32%), followed by breast (29%), thyroid (22%), and salivary gland (2%). Other site comprised 15% of cases. In lymph node, reactive lymphadenitis was the most common benign lesion (42.7%) and metastatic squamous cell carcinoma was the commonest malignant lesion(12.62%). In breast, benign proliferative breast disease was the most common(84.1%) and ductal carcinoma was commonest among malignant lesions(8.5%). Among thyroid lesions, benign proliferative thyroid disease was the commonest one (47.9%)followed by papillary carcinoma among malignant lesions(11.3%).Among salivary gland lesions, Chronic sialadenitis was common inflammatory lesion (37.5%) followed by pleomorphic adenoma among benign lesions(25%) and carcinoma comprised 25%. Lipoma was the commonest lesion ( 63%) from other sites. Conclusion: Wide range of lesions, both benign and malignant, can be diagnosed by FNAC thus restricting surgery to cases only requiring further histopathological evaluation. DOI: http://dx.doi.org/10.3126/mjsbh.v9i2.5022 Medical Journal of Shree Birendra Hospital Vol.9(2) 2010: 25-29  

scholarly journals Mammographic evaluation of palpable breast masses with pathological correlation: a tertiary care centre study in Nepal

1970 ◽  
Vol 32 (2) ◽  
pp. 21-25 ◽  
Author(s):  
G Gurung ◽  
RK Ghimire ◽  
B Lohani
Keyword(s):  
Breast Cancer ◽  
Benign Lesion ◽  
Tertiary Care ◽  
False Negative ◽  
Malignant Lesion ◽  
Institute Of Medicine ◽  
Breast Lump ◽  
Major Health Problem ◽  
Malignant Lesions ◽  
Palpable Breast

Introduction: Breast cancer is one of the major health problem for all countries. . In Nepal , breast cancer is the second most common cancer in female. Early detecting tools like mammography can able to detect location , size, morphology, and nature of breast lesions that can help to reduced mortality and morbidity from breast cancer significantly. Methods: This prospective study was carried out at the department of Radiology, Surgery and Pathology for a period of one year. A total of 100 patients with clinically palpable breast lump were subjected to mammography and subsequently to FNA or biopsy. The mammograms were reviewed by two senior consultant radiologists and pathology by a senior pathologist. Results: Out of 100 patients, 65% had mammographic features of benign lesion and 35% had features of malignancy. Pathology revealed 64% of lesion to be benign and 36% of lesion to be malignant. There were four false negative (6.2%) and three false positive (8.6%) cases. The sensitivity and specificity of mammography were 88.9% and 95.53% respectively. The mean age of patient with malignant lesion was 46.3 years (SD=11.5) and 34.7 years (SD=10.6) for benign lesions. Among malignant lesion 37.1% had lobulated, 14.3% had oval, 31.4% round and 17.1% had irregular shape with spiculated margin in 60% and indistinct margins in 34.3%. Among benign 7.7% showed lobulated shape, 41.5% oval and 50.8% round shape. Circumscribed margin was found in 93.9% of benign and 5.7% of malignant lesions. Punctuate and polymorphic calcification was found in malignant lesions (25.7% and 5.7%). Secondary changes were found in only in the malignant cases. Halo sign was found only in benign cases and most common in fibroadenoma (38.4%). Conclusions: Mammography is an effective diagnostic tool for benign and malignant characteristic of palpable breast mass. Keywords: Breast lump; mammography; micro calcification DOI: http://dx.doi.org/10.3126/joim.v32i2.4940 Journal of Institute of Medicine, August, 2010; 32: 21-25

scholarly journals THE VALUE OF MODIFIED TRIPLE ASSESSMENT IN THE DIAGNOSIS OF PALPABLE BREAST LUMPS

2019 ◽  
Vol 3 (5) ◽  
Author(s):  
Dr. S. Raviraj ◽  
Dr. V. Vinitharan
Keyword(s):  
Benign Lesion ◽  
Malignant Lesion ◽  
Clinical Problem ◽  
Breast Lesions ◽  
Validity And Reliability ◽  
Early Evaluation ◽  
Triple Assessment ◽  
Palpable Breast ◽  
Breast Lumps ◽  
Common Clinical Problem

Breast Lumps in females are a common clinical problem which requires rapid and early evaluation with an important aim of excluding any breast malignant lesion. We have modified this approach by substituting mammogram with ultrasound for the assessment of breast lesions. Distinction of benign lesion of breast from malignant lesion is of paramount importance for patient care and proper management. An early and accurate diagnosis is important because the treatment can be initiated much earlier for the better prognosis. Nowadays Triple assessment has been used as a main diagnostic method in the evaluation of breast lesions. Therefore it is important to evaluate the validity and reliability of triple assessment in the evaluation of breast lesion.

scholarly journals SUPERFICIAL CERVICAL SWELLING IN CHILDREN

2011 ◽  
Vol 17 (01) ◽  
pp. 151-155
Author(s):  
MUHAMMAD SALEEM SHEIKH ◽  
MASOOD AKHTAR ◽  
MUHAMMAD AMIN SHEIKH
Keyword(s):  
Sensitivity And Specificity ◽  
Hodgkin’S Lymphoma ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Nodular Goiter ◽  
High Rate ◽  
Hodgkin's Lymphoma ◽  
Tuberculous Lymphadenitis ◽  
Cervical Swelling ◽  
Malignant Lesions

Fine needle aspiration cytology (FNAC) is commonly used first line diagnostic test for palpable cervical swelling by ENT and Head & Neck surgeon. Objective: To analyze the diagnostic importance of FNAC by knowing its sensitivity and specificity in children having palpable cervical swelling. Design: Prospective study. Setting: Department of ENT and Head Neck Surgery QAMC, Bahawalpur. Period: July 2006 to June 2007. Material And Methods: 82 cases of superficial cervical swelling with ages between 5 and 12 years were selected. Most of them were of poor socioeconomic class. All underwent FNAC for diagnosis and results were analyzed after comparing with histopathology examinations. Results: Out of 432 total patients (of all ages) who attended the ENT department during the study period, only 82 were selected for the research which fulfilled the inclusion criteria. These were 5-12 years old, both sexes, 47 boys (57.3%) and 35 girls (42.75%). Sixty eight (83%) patients had benign diseases while 14 patients (17%) had malignant lesions. Out of the 68 benign lesion (44.11%) were reaction hyperplasia (non specific inflammation), followed by tuberculous lymphadenitis (38.23%), cystic masses (5.88%), benign tumours (4.4 %) and nodular goiter (7.35%). Out of 14 malignant lesions, 6 (42.85%) had Hodgkin's Lymphoma, 2 (14.28 %) had Non Hodgkin's Lymphoma, 3(21.42% ) patients had squamous cell carcinoma and 1 (7.14%) patient each of rhabdomyosarcoma, undifferentiated carcinoma and pleomorphic adenoma. In our study sensitivity and specificity of FNAC to diagnose the malignant lesion was 85.7% and 89.7% respectively. Accuracy of FNAC in our study was 89.0%. Conclusion: FNAC is highly helpful to diagnose the pathology of cervical swelling in children. It has high rate of sensitivity, specificity and accuracy to diagnose the malignancy in these lesions. Proper and specific sampling needs complete cooperation of the child and sedation may be necessary for this. Expertise is required for FNAC reporting.

scholarly journals RETROSPECTIVE ANALYSIS OF MAMMOGRAM, SONOMAMMOGRAM AND ITS HISTOPATHOLOGICAL CORRELATION AS AN AID FOR DIAGNOSIS OF BREAST LESIONS

2021 ◽  
pp. 1-4
Author(s):  
Sathish babu ◽  
Arifkhan Sainudeen ◽  
Abdul Eksana
Keyword(s):  
Breast Cancer ◽  
Breast Imaging ◽  
Ductal Carcinoma ◽  
Histopathological Examination ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Breast Lesions ◽  
Care Hospital ◽  
Malignant Breast ◽  
Malignant Lesions

INTRODUCTION: Breast cancer is the most common cancer impacting 2.1 million women each year and also relates to the most cancer related deaths in women. In 2018, it was estimated that 627,000 women died from breast cancer which approximates to 15 % of all cancer related deaths among women [1]. The triple test– clinical examination, mammography and core biopsy helps in differentiating benign and malignant lesions. Histopathological examination is considered being the gold standard test for confirming malignant lesions and forms the basis of management. AIM: To assess sensitivity of mammogram with ultrasonography in diagnosing various breast lesions and to correlate the categorized breast lesions (BI-RADS) with histopathology reports and thereby obtain specificity and NPV of evaluation using Mammogram and ultrasonography. STUDY DESIGN: Retrospective analytical study. Study Period: July 2018 – July 2019. METHODS: The results of ultrasonography and mammography of 72 cases diagnosed clinically with breast lesions over the period of one year in tertiary health care hospital were compared with histopathology reports. RESULTS: The mean age of the patients was 45.65 ± 3.19. Our results showed that in histopathology reports in 20 patients (27.78%) were malignant, 51 cases (70.83%) had benign disease and 1 case 1.39% was borderline malignant. Fibroadenoma was the commonest benign lesion whereas infiltrating ductal carcinoma was the most common malignant lesion. Breast Imaging – Reporting and Data System (BIRADS) by mammogram revealed category II in 54.1%, III in 20.8%, IV in 16.6% and V in 8.3%. The specificity of mammography alone in diagnosing malignant breast lesions was 90.1%. When combined (ultrasound and mammogram), the specificity in diagnosing malignant breast lesion was 98.5% CONCLUSION: Mammography and sono-mammogram plays an important role in the diagnostic and surgical management of breast lesions with correlative histopathology evaluation. The diagnostic accuracy shows significant improvement when mammogram was combined with ultrasound correlation and thereby improving sensitivity and specificity of diagnosing malignant breast lesions.

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