scholarly journals Polysomnographic evaluation of sleep quality and quantitative variables in women as a function of mood, reproductive status, and age

2012 ◽  
Vol 14 (4) ◽  
pp. 413-424
Keyword(s):  
Sleep Onset ◽  
Onset Time ◽  
Sleep Time ◽  
Reproductive Status ◽  
Cross Sectional ◽  
Stage 4 ◽  
Stage 1 ◽  
Main Effects ◽  
The Impact ◽  
Normal Controls

This archival cross-sectional investigation examined the impact of mood, reproductive status (RS), and age on polysomnographic (PSG) measures in women. PSG was performed on 73 normal controls (NC) and 64 depressed patients (DP), in the course of studies in menstruating, pregnant, postpartum, and peri- and postmenopausal women. A two-factor, between-subjects multivariate analysis of variance (MANOVA) was used to test the main effects of reproductive status (RS: menstrual vs pregnant vs postpartum vs menopausal) and diagnosis (NC vs DP), and their interaction, on PSG measures. To further refine the analyses, a two-factor, between subjects MANOVA was used to test the main effects of age (19 to 27 vs 28 to 36 vs 37 to 45 vs 46+ years) and diagnosis on the PSG data. Analyses revealed that in DP women, rapid eye movement (REM) sleep percentage was significantly elevated relative to NC across both RS and age. Significant differences in sleep efficiency, Stage 1%, and REM density were associated with RS; differences in total sleep time, Stage 2 percentage, and Stage 4 percentage were associated with differences in age. Both RS and age were related to differences in sleep latency, Stage 3 percentage, and Delta percentage. Finally, wake after sleep onset time, REM percentage, and REM latency did not vary with respect to RS or age. Overall, this investigation examined three major variables (mood, RS, and age) that are known to impact sleep in women. Of the variables, age appeared to have the greatest impact on PSG sleep measures, reflecting changes occurring across the lifespan.

Links between sleep and body mass index in bipolar disorders: An exploratory study

2015 ◽  
Vol 30 (1) ◽  
pp. 89-93 ◽  
Author(s):  
C. Boudebesse ◽  
P.-A. Geoffroy ◽  
C. Henry ◽  
A. Germain ◽  
J. Scott ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Sleep Disturbances ◽  
Sleep Onset ◽  
Bipolar Disorders ◽  
Sleep Time ◽  
Sleep Efficiency ◽  
Sleep Onset Latency ◽  
Cross Sectional ◽  
Sleep Parameters

AbstractStudy objectives:Obesity and excess bodyweight are highly prevalent in individuals with bipolar disorders (BD) and are associated with adverse consequences. Multiple factors may explain increased bodyweight in BD including side effects of psychotropic medications, and reduced physical activity. Research in the general population demonstrates that sleep disturbances may also contribute to metabolic burden. We present a cross-sectional study of the associations between body mass index (BMI) and sleep parameters in patients with BD as compared with healthy controls (HC).Methods:Twenty-six French outpatients with remitted BD and 29 HC with a similar BMI completed a 21-day study of sleep parameters using objective (actigraphy) and subjective (PSQI: Pittsburgh Sleep Quality Index) assessments.Results:In BD cases, but not in HC, higher BMI was significantly correlated with lower sleep efficiency (P = 0.009) and with several other sleep parameters: shorter total sleep time (P = 0.01), longer sleep onset latency (P = 0.05), higher fragmentation index (P = 0.008), higher inter-day variability (P = 0.05) and higher PSQI total score (P = 0.004).Conclusions:The findings suggest a link between a high BMI and several sleep disturbances in BD, including lower sleep efficiency. Physiological mechanisms in BD cases may include an exaggeration of phenomena observed in non-clinical populations. However, larger scale studies are required to clarify the links between metabolic and sleep-wake cycle disturbances in BD.

scholarly journals Custo da terapia tópica em pacientes com lesão por pressão

2018 ◽  
Vol 12 (10) ◽  
pp. 2555
Author(s):  
Daniel De Macêdo Rocha ◽  
Sandra Maria Gonçalves Bezerra ◽  
Aline Costa De Oliveira ◽  
Josiane Santos Silva ◽  
Italo Arão Pereira Ribeiro ◽  
...  
Keyword(s):  
Cost Analysis ◽  
Pressure Ulcer ◽  
Chronic Wounds ◽  
Topical Therapy ◽  
Lower Limbs ◽  
Cross Sectional ◽  
Stage 4 ◽  
The Cost ◽  
The Impact ◽  
Complex Wounds

RESUMOObjetivo: avaliar o custo da terapia tópica em pacientes com lesão por pressão. Método: estudo quantitativo, transversal e analítico realizado em um ambulatório de referência para tratamento de feridas complexas. A amostra constituiu-se de 20 participantes que procuraram o serviço para a avaliação e o tratamento da lesão. Utilizou-se, para a coleta de dados, um formulário para a caracterização sociodemográfica, clínica, terapêutica e de análise de custo. Realizou-se a análise por meio da estatística descritiva e inferencial. Resultados: houve o predomínio do sexo masculino, com idade média de 56,6 anos e de pacientes procedentes de Teresina. Prevaleceram feridas crônicas, localizadas na região sacral e em estágio 4. A análise do custo mostrou que as lesões em membros inferiores com odor fétido, tecido desvitalizado, exsudato intenso e que foram tratadas com o carvão ativado, espuma com prata e hidrofibra apresentaram maior custo. Conclusão: mostrou-se que a lesão por pressão apresentou alto custo determinado pelas características clínicas e métodos terapêuticos adotados. Evidenciou-se a necessidade da implementação de medidas preventivas e de novos estudos para mostrar o impacto da lesão nos serviços de saúde. Descritores: Ferimentos e Lesões; Lesão por Pressão; Bandagem; Custo e Análise de Custos; Enfermagem; Cuidados de Enfermagem.ABSTRACT Objective: to evaluate the cost of topical therapy in patients with pressure ulcers. Method: quantitative, cross-sectional and analytical study carried out at a reference outpatient clinic for the treatment of complex wounds. The sample consisted of 20 participants who sought the service for evaluation and the treatment of the ulcer. A form for sociodemographic, clinical, therapeutic and cost analysis was used for data collection. The analysis was carried out through descriptive and inferential statistics. Results: there was a predominance of males, with a mean age of 56.6 years and of patients coming from Teresina. Chronic wounds prevailed, located in the sacral region and in stage 4. The cost analysis showed that lesions in the lower limbs, with fetid odor, devitalized tissue, intense exudate and that were treated with activated charcoal, silver foam and hydrofiber presented higher cost. Conclusion: it was shown that the pressure ulcer presented a high cost determined by the clinical characteristics and therapeutic methods adopted. The need to implement preventive measures and new studies to show the impact of the injury on health services was evidenced. Descriptors: Wounds and Injuries; Pressure Ulcer; Bandages; Costs and Cost Analysis; Nursing; Nursing Care. RESUMEN Objetivo: evaluar el costo de la terapia tópica en pacientes con lesión por presión. Método: estudio cuantitativo, transversal y analítico realizado en un ambulatorio de referencia para el tratamiento de heridas complejas. La muestra se constituyó de 20 participantes que buscaban el servicio para la evaluación y el tratamiento de la lesión. Se utilizó, para recolección de datos, un formulario para caracterización sociodemográfica, clínica, terapéutica y análisis de costo. Se realizó el análisis por medio de la estadística descriptiva e inferencial. Resultados: hubo el predominio del sexo masculino, con una edad media de 56,6 años y de pacientes procedentes de Teresina. Prevalecían heridas crónicas, localizadas en la región sacra y en etapa 4. El análisis del costo mostró que las lesiones en miembros inferiores, con olor fétido, tejido desvitalizado, exudado intenso y que fueron tratadas con el carbón activado, espuma con plata e hidrofibra presentaron mayor costo. Conclusión: se mostró que la lesión por presión presentó alto costo, siendo determinada por las características clínicas y métodos terapéuticos adoptados. Se evidenció la necesidad de la aplicación de medidas preventivas y de nuevos estudios para mostrar el impacto de la lesión en los servicios de salud. Descriptores: Heridas y Lesiones; Úlcera por Presión; Vendajes; Costos y Análisis de Costo; Enfermería; Atención de Enfermería.

Agreement between the newly developed OCT glaucoma staging system and the standardized visual field glaucoma staging system 2

2021 ◽  
pp. 112067212110143
Author(s):  
Elshimaa A Mateen Mossa ◽  
Heba Khallaf ◽  
Khulood Muhammad Sayed
Keyword(s):  
Visual Field ◽  
Open Angle Glaucoma ◽  
Staging System ◽  
Control Group ◽  
Ganglion Cell Complex ◽  
Automated Perimetry ◽  
Cross Sectional ◽  
Stage 4 ◽  
Staging Systems ◽  
Stage 1

Purpose: The purpose of this research was to assess the agreement between the new optical coherence tomography (OCT) glaucoma staging system (GSS) and the visual field (VF) GSS 2 (GSS2). Methods: This is a cross-sectional study of 161 eyes of 110 patients with controlled primary open-angle glaucoma (POAG). All eyes were subjected to VF examination using standard automated perimetry and Humphrey field analyzer II 750. GSS2 was used for the classification of the VF defects’ severity. OCT of the optic disc and the macular ganglion cell complex (GCC) was performed using RTVue. Patients were classified by OCT GSS into six stages. Results: The study examined 161 eyes of 110 patients with controlled POAG. The staging according to VF GSS2 was as follows: stage 0 (12.42%), border stage (12.42%), stage 1 (13.04%), stage 2 (14.29%), stage 3 (14.28%), stage 4 (14.28%), and stage 5 (19.25%). The staging by OCT GSS was as follows: stage 0 (18.6 %), border stage (17.3%), stage 1 (6.8%), stage 2 (9.31%), stage 3 (6%), stage 4 (11.8%), and stage 5 (30.43%). The sensitivity of the new OCT GSS was different in different stages of glaucoma. In this study, no normal control group was considered; thus, the specificity could not be calculated. There was moderate agreement between the two staging systems. Conclusions: OCT GSS is a reliable and objective method for diagnosing and monitoring glaucoma. Correlations were found between GSS2, inferior and total macular GCC thickness values, and cup-to-disc ratios, so considering these items as additional parameters may make this new classification even more sensitive than VF GSS2.

scholarly journals P160 A trial of a position modification device for the prevention of supine sleep during pregnancy

2021 ◽  
Vol 2 (Supplement_1) ◽  
pp. A73-A73
Author(s):  
D Wilson ◽  
C Whenn ◽  
S Walker ◽  
M Barnes ◽  
M Howard
Keyword(s):  
Total Sleep Time ◽  
Night Shift ◽  
Sleep Onset ◽  
Late Pregnancy ◽  
Sleep Time ◽  
Third Trimester ◽  
Sleep Study ◽  
Supine Sleep ◽  
Efficiency Control ◽  
The Impact

Abstract Self-reported supine position at sleep onset during late pregnancy is related to a 2.6x increase in stillbirth risk, possibly due to the enlarged uterus compressing major blood vessels supplying the placenta. This study aimed to test the effectiveness of a pillow designed to decrease supine sleep in pregnant women. Twelve women in the third trimester of pregnancy used their own pillows for a control week and the intervention pillow for 1 week, in randomised order. Sleep position for each night of both weeks was monitored with the Night Shift Sleep Positioner, with a sleep study (WatchPat300) on the last night of each week to measure the impact of the intervention on SDB. During the control week, the women slept supine for a median of 19.9% (IQR = 11.6, 27.4) of total sleep time (TST), compared to a median of 20.4% (10.2, 31.0) TST using the intervention pillow (p = .64). Use of the intervention pillow did not impact sleep efficiency (control = 85.3% (80.7, 88.0) v. intervention = 85.2% (78.3, 89.0), p = .48). On the sleep study night, supine sleep was reduced in the intervention compared to control condition (12.9% vs. 17.7%, p = .04), but AHI did not differ (intervention = 2.6/hr (0.8, 6.7) vs. control = 1.5/hr (0.6, 3.6), p = .11). We found that the adoption of a pillow designed to discourage supine sleep was not effective in late pregnancy. Considering the reasonably high amount of supine sleep in our participants, alternative devices should be investigated.

scholarly journals P003 The impact of forced wake from overnight polysomnography on multiple sleep latency test results

2021 ◽  
Vol 2 (Supplement_1) ◽  
pp. A22-A23
Author(s):  
A Amaranayake ◽  
S Frenkel ◽  
P Lyell ◽  
A Southcott
Keyword(s):  
Diagnostic Accuracy ◽  
Sleep Latency ◽  
Total Sleep Time ◽  
Sleep Onset ◽  
Sleep Time ◽  
Multiple Sleep Latency Test ◽  
Test Results ◽  
The Impact ◽  
Multiple Sleep Latency ◽  
Overnight Polysomnography

Abstract Introduction The multiple sleep latency test (MSLT) is used to diagnose disorders of hypersomnolence. Although internationally-recognised protocols do not stipulate whether patients should be woken from the preceding overnight polysomnography (PSG), many labs wake their patients for logistic reasons. This study analyses the impact on PSG and MSLT parameters of forced wake (FW) from the overnight PSG compared with unrestricted sleep (US). Methods 400 consecutive patients (FW=200; US=200) undergoing PSG/MSLT were included and the following parameters were compared: Epworth Sleepiness Scale (ESS), Morningness-Eveningness Questionnaire score (MEQ), PSG total sleep time (TST), wake-up time from the PSG, overall MSLT sleep latency (MSL), individual nap latencies (SLNap 1–4), number of MSLT naps with sleep-onset REM periods (#SOREMP), and percentage of MSLTs with overall MSL<8 minutes (%MSLT<8). Results The 2 groups were well-matched for ESS and MEQ. The FW group had more males (49% vs 39%). When compared to FW, patients with US had longer TST (+38 minutes; p=<0.0001), later wake-up time (+52 minutes; p<0.0001), longer MSL (+1.9 minutes; p=0.0049), 50% fewer #SOREMP (p=0.0224), and 16% fewer %MSLT<8 (p=0.0018). SLNap1 increased by 1.5 minutes (p=0.0623), SLNap2 increased by 2.0 minutes (p=0.0067), SLNap3 increased by 0.75minutes (p=0.0533) and SLNap4 increased by 2.5 minutes (p=0.0059). Discussion Allowing patients to have unrestricted sleep on the night prior to the MSLT resulted in significantly longer TST, longer sleep latencies during the MSLT, fewer SOREMP and fewer tests with MSL<8 minutes. International protocols should stipulate unrestricted sleep on the PSG prior to the MSLT to improve diagnostic accuracy.

Measure of Atopic Dermatitis Disease Severity Using Actigraphy

2014 ◽  
Vol 18 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Laura F. Sandoval ◽  
Karen Huang ◽  
Jenna L. O'Neill ◽  
Cheryl J. Gustafson ◽  
Emily Hix ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Sleep Quality ◽  
Disease Severity ◽  
Sleep Disturbances ◽  
Sleep Onset ◽  
Sleep Time ◽  
Random Effects Models ◽  
Short Course ◽  
Wrist Actigraphy ◽  
The Impact

Background: Analyzing adherence to treatment and outcomes in atopic dermatitis is limited by methods to assess continual disease severity. Atopic dermatitis significantly impacts sleep quality, and monitoring sleep through actigraphy may capture disease burden. Purpose: To assess if actigraphy monitors provide continuous measures of atopic dermatitis disease severity and to preliminarily evaluate the impact of a short-course, high-potency topical corticosteroid regimen on sleep quality. Methods: Ten patients with mild to moderate atopic dermatitis applied topical fluocinonide 0.1% cream twice daily for 5 days. Sleep data were captured over 14 days using wrist actigraphy monitors. Investigator Global Assessment (IGA) and secondary measures of disease severity were recorded. Changes in quantity of in-bed time sleep were estimated with random effects models. Results: The mean daily in-bed time, total sleep time, and wake after sleep onset (WASO) were 543.7 minutes (SEM 9.4), 466.0 minutes (SEM 7.7), and 75.0 minutes (SEM 3.4), respectively. WASO, a marker of disrupted sleep, correlated with baseline (ρ = .75) and end of treatment IGA (ρ = .70). Most patients did not have marked changes in sleep. IGA scores declined by a median change of 1 point at days 7 ( p = .02) and 14 ( p = .008). Conclusions: Using actigraphy, atopic dermatitis disease severity positively correlated with sleep disturbances. Actigraphy monitors were well tolerated by this cohort of atopic dermatitis subjects.

Sleep Pattern in Patients with β-Thalassemia Minor.

Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 3819-3819
Author(s):  
Turker Cetin ◽  
Sinan Yetkin ◽  
Fuat Ozgen
Keyword(s):  
Total Sleep Time ◽  
Sleep Time ◽  
Beta Thalassemia ◽  
Chronic Anemia ◽  
Stage 4 ◽  
Thalassemia Minor ◽  
Rem Latency ◽  
Periodic Leg Movement ◽  
Leg Movement ◽  
Normal Controls

Abstract Introduction: Although sleep disturbances, anxiety, and sadness are some of the most common symptoms in patients with chronic anemia, there is little knowledge about sleep structures in patients with chronic anemia such as thalassemia. The aim of this study is to investigate sleep structure in patients with beta-thalassemia minor. Methods: Seventeen drug free subjects with beta-thalassemia minor and age-matched healthy subjects were enrolled in the study. The patients were diagnosed by complete blood count including reticulocyte count and hemoglobin electrophoresis. In addition, blood smear, erythrocyte sedimentation rate, serum level of urea, creatinine, indirect bilirubin, lactate dehydrogenase, ferritin, folate, vitamin B12, and thyroid hormones were determined. The other causes of anemia were ruled out. Subjects also were screened for excessive daytime sleepiness with the Epworth sleepiness scale, and for insomnia using insomnia severity index. All subjects slept in laboratory for two consecutive nights. First night served as adjustment nights. The second night results were used for analysis. Their sleep patterns were compared with healthy normal controls. Sleep was recorded and scored according to the criteria of Rechtschafffen and Kales. Results: Four female and thirteen male patients (mean age, 26.1 ± 5.9 years) completed both nights of sleep recordings. In patients groups, one patient complained snoring and daytime sleepiness. Nine of them complained daytime weakness. Ten patients were anemic (Hb < 13,2 g/dL for men, <11,7 g/dL for women). In polysomnographic investigation, the patients with β-thalassemia minor showed increased total sleep time, sleep period time, PLM index and the increased percentage of REM sleep. The percentage of stage 4, and REM latency are decreased. Sleep fragmentation and periodic leg movement syndrome (PLMS) have been reported. Conclusion: The disturbances of sleep continuity was prominent finding in this polysomnographic study. They also showed decreased REM latency and the increased percentage of REM sleep, although they didn’t have major depressive disorders. Polysomnographic variables in patients with beta-thalassemia minor Polysomnographic variables Thalassemia (n: 17) Normal Controls (n: 17) Results (P value) NS: not sinificant, REM: rapid eye movement, PLM: periodic leg movement Sleep effiency 90.8±4.6 93.7±2.1 NS Total time in bed (min) 467.6±60.1 415.1±51.1 .008 Total sleep time (min) 425.8.4±65.1 388.5±49.2 .031 Sleep period time (min) 453.2.4±62.0 404.4±52.2 .012 Sleep latency (min) 9.9±9.0 8.2±5.2 NS Percentage of stage 1 (SPT) 2.5±1.0 1.8±1.1 NS Percentage of stage 2 (SPT) 61.9±6.9 64.1±7.3 NS Percentage of stage 3 (SPT) 4.8±1.9 6.5±2.4 NS Percentage of stage 4 (SPT) 8.0±6.4 12.2±6.1 .022 Percentage of stage REM (SPT) 16.3±3.8 12.5±3.4 .006 REM latency 67.9±25.0 96.8±32.5 .016 PLM index 7.4 ± 5.7 0.0 .000

scholarly journals Chronotype-Dependent Changes in Sleep Habits Associated with Dim Light Melatonin Onset in the Antarctic Summer

2019 ◽  
Vol 1 (3) ◽  
pp. 352-366 ◽  
Author(s):  
Ana Silva ◽  
Diego Simón ◽  
Bruno Pannunzio ◽  
Cecilia Casaravilla ◽  
Álvaro Díaz ◽  
...  
Keyword(s):  
Light Exposure ◽  
Time Windows ◽  
Sleep Onset ◽  
Onset Time ◽  
Sleep Habits ◽  
Subtle Difference ◽  
Dim Light Melatonin Onset ◽  
Dim Light ◽  
The Antarctic ◽  
The Impact

Dim light melatonin onset (DLMO) is the most reliable measure of human central circadian timing. Its modulation by light exposure and chronotype has been scarcely approached. We evaluated the impact of light changes on the interaction between melatonin, sleep, and chronotype in university students (n = 12) between the Antarctic summer (10 days) and the autumn equinox in Montevideo, Uruguay (10 days). Circadian preferences were tested by validated questionnaires. A Morningness–Eveningness Questionnaire average value (47 ± 8.01) was used to separate late and early participants. Daylight exposure (measured by actimetry) was significantly higher in Antarctica versus Montevideo in both sensitive time windows (the morning phase-advancing and the evening phase-delaying). Melatonin was measured in hourly saliva samples (18–24 h) collected in dim light conditions (<30 lx) during the last night of each study period. Early and late participants were exposed to similar amounts of light in both sites and time windows, but only early participants were significantly more exposed during the late evening in Antarctica. Late participants advanced their DLMO with no changes in sleep onset time in Antarctica, while early participants delayed their DLMO and sleep onset time. This different susceptibility to respond to light may be explained by a subtle difference in evening light exposure between chronotypes.

scholarly journals Sleep Parameters in Short Daily versus Conventional Dialysis: An Actigraphic Study

2017 ◽  
Vol 2017 ◽  
pp. 1-6
Author(s):  
Ludimila D’Avila e Silva Allemand ◽  
Otávio Toledo Nóbrega ◽  
Juliane Pena Lauar ◽  
Joel Paulo Russomano Veiga ◽  
Einstein Francisco Camargos
Keyword(s):  
Total Sleep Time ◽  
Linear Regression Analysis ◽  
Sleep Onset ◽  
Objective Measure ◽  
Sleep Time ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Wake Time ◽  
Daily Dialysis ◽  
Sleep Parameters

Previous studies have observed worse sleep quality in patients undergoing conventional dialysis as compared to daily dialysis. Our aim was to compare the sleep parameters of patients undergoing daily or conventional dialysis using an objective measure (actigraphy). This cross-sectional study was performed in three dialysis centers, including a convenience sample (nonprobability sampling) of 73 patients (36 patients on daily hemodialysis and 37 patients on conventional hemodialysis). The following parameters were evaluated: nocturnal total sleep time (NTST), expressed in minutes; wake time after sleep onset (WASO), expressed in minutes; number of nighttime awakenings; daytime total sleep time (DTST), expressed in minutes; number of daytime naps; and nighttime percentage of sleep (% sleep). The Mini-Mental State Examination and the Beck Depression Inventory were also administered. The mean age was 53.4  ±  17.0 years. After adjustment of confounding factors using multiple linear regression analysis, no difference in actigraphy parameters was detected between the groups: NTST (p=0.468), WASO (p=0.88), % sleep (p=0.754), awakenings (p=0.648), naps (p=0.414), and DTST (p=0.805). Different from previous studies employing qualitative analysis, the present assessment did not observe an influence of hemodialysis modality on objective sleep parameters in chronic renal patients.

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