scholarly journals Blood Glucose Level And Candida spp. Growth In Elderly Diabetes Melitus Patients

2018 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
Rifqoh Rifqoh ◽  
Syaidatul Aslamiah ◽  
Jujuk Anton Cahyono ◽  
Erpan Roebiakto

Diabetes mellitus is a presdisposing factor against infection, especially in orofacial area. Infectious diseases are more frequent serious in patients with diabetes mellitus, which potentially increases their morbimortality. The more frequent oral mucosa infection of DM patients is candidiasis which caused by Candida spp. This research is aimed to obtain the correlation between fasting blood glucose level and Candida spp. growth in elderly diabetes mellitus patients. This analytical survey research used cross-sectional design through GOD-PAP methode for fasting blood glucose level test and macroscopic method for total colony of Candida spp. growth. The result of fasting blood glucose level test average 186,06 mg/dl the highest level is 492,90 mg/dl and the lowest one is 72,08 mg/dl. Meanwhile, the result of Candida spp. is 131 at the average and the highest growth is 350 and the lowest one is 12 colonies. The result of the research indicates that there is a rising of Candida spp. to level of fasting blood glucose in elderly diabetes mellitus patients. Based on correlational test of spearman, it gains significant value 0,001 < α = 0,005 of that shows there is a correlation between fasting blood glucose level and Candida spp. growth in diabetes mellitus elderly patients with the strenght relation (r) = 0,572 which means in medium level. Further researches about the influence to the other presdisposing factors of Candida spp. growth are recommended

2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Gracia Rorong ◽  
Stefana Kaligis ◽  
Diana Purwanto

Abstract: Glucose is a main compound that has important role in preparation and development  of energy in human body. Blood glucose level is the amount of glucose in the blood. One of the factors that affects blood glucose level is body weight. Body weight is affected by several factors, such as aged, gender, and physical activities. Overweight may cause insulin resistance, results in increasing of the blood glucose level. This study aimed to describe the fasting blood glucose level at students Faculty of Medicine year 2011 Sam Ratulangi University with Body Mass Index (BMI) ≥23 kg/m2. Research method used for this study was cross sectional descriptive survey with purposive sampling method. From 26 respondents, 12 overweight (BMI ≥23 kg/m2) respondents (46,15%) had average fasting blood glucose level 85,4 mg/dL and 14 obese (BMI ≥25 kg/m2) respondents (53,85%) had average fasting blood glucose level 86 mg/dL. Conclusion: the description of fasting blood glucose level at students Faculty of Medicine year 2011 Sam Ratulangi University with Body Mass Index (BMI) ≥23 kg/m2 is at normal level (80-100 mg/dL). Keywords: BMI ≥23 kg/m2, Fasting blood glucose, students year 2011     Abstrak: Glukosa merupakan suatu molekul utama yang berperan penting dalam penyediaan dan pembentukan energi di dalam tubuh. Kadar glukosa darah adalah jumlah kandungan glukosa dalam darah. Salah satu faktor yang mempengaruhi kadar glukosa darah adalah berat badan. Berat badan dipengaruhi oleh beberapa faktor, antara lain usia, jenis kelamin, dan aktivitas fisik. Kelebihan berat badan dapat menyebabkan resistensi insulin sehingga kadar glukosa dalam darah meningkat. Peningkatan kadar glukosa darah merupakan salah satu penanda sindroma metabolik. Penelitian ini bertujuan untuk mengetahui gambaran kadar glukosa darah puasa pada mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi Angkatan 2011 dengan Indeks Massa Tubuh (IMT) ≥23 kg/m2. Jenis penelitian berupa penelitian survey deskriptif cross sectional dengan metode purposive sampling. Sampel penelitian sebanyak 26 orang responden. Hasil penelitian ini didapatkan 12 orang responden (46,15%) yang overweight (IMT ≥23 kg/m2) memiliki rata-rata kadar glukosa darah puasa 85,4 mg/dL dan 14 orang responden (53,85%) yang obesitas (IMT ≥25 kg/m2) memilki rata-rata kadar glukosa darah puasa 86 mg/dL. Simpulan: semua responden mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi Angkatan 2011 memiliki kadar glukosa darah puasa normal (80-100 mg/dL). Kata Kunci: Glukosa darah puasa, IMT ≥23 kg/m2, mahasiswa angkatan 2011


1970 ◽  
Vol 9 (1) ◽  
pp. 45-48
Author(s):  
S Mohal ◽  
DK Mondal ◽  
PK Chowdhury ◽  
A Khanom ◽  
KM Shamim

Context: Scientific studies revealed the hypoglycaemic properties of momordica charantia. The present study was carried out to find out microscopically whether Momordica charantia (karela) has got any impact lowering of FBG (Fasting Blood Glucose) level in diabetes mellitus. Study type: an experiemental study. Setting: Anatomy department of the then IPGMR (Institute of Post Graduate Medicine and Research) at present BSMMU (Bangabandhu Sheikh Mujib Medical University) and BIRDEM (Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine & Metabolic Disorders). Subjects: Sixty five healthy young Long Evans rats of male sex weighing 150 to 280gm aged between 10 to 12 weeks were used in this study. Methods: The rats were divided into four equal groups depending on their different sorts of dietry feeding and drug treatment. Main outcome measures: variation of differential FBG level in different groups of rat. Result: Mean 'initial' and 'final' (on day 7 and day 51 from Streptozotocin/vehicle injection) fasting blood glucose (FBG) level in the control group (Group-A) was 7.872 ± 0.60 and 8.55 ± 0.82 respectively. Therefore the mean (FBG) increased by about 13% (P = 0.022*) which is higher than that of the initial value. In untreated diabetic group the mean initial (FBG) level was 25.95 ± 8.90 and the mean final was 24.02 ± 4.08. So here, the (FBG) level decreased by about 13% (P = 0.557). On the other hand, in the insulintreated diabetic rats the mean initial (FBG) level was 24.35 ± 6.81 and the mean final was 8.38 ± 5.02, which is lower (P = 0.000*) & in the karela–treated diabetic rats, the initial (FBG) level was 23.03 ± 5.70 and the mean final was 5.65 ± 1.29 which is lower* (P = 0.000*). The value in the insulin-treated diabetic rats & in the karela-treated diabetic rats were significantly lower than that of the untreated diabetic rats (P = 0.007) & (P= 0.005) respectively. But there was no significant difference between the insulin-treated diabetic rats & the karela-treated diabetic rats (P = 0.605) in this regard. Conclusion: Karela showed a tendency of acting against hyperglycemic effects of Streptozotocin-induced diabetes mellitus. However, further investigations are recommended for establishing karela as a safe, useful effective anti- hyperglycemic agent as well as antidiabetogenic agent. Key words: Diabetes mellitus; Hyperglycemia; Momordica charantia (karela) DOI: http://dx.doi.org/ 10.3329/bja.v9i1.8148 Bangladesh Journal of Anatomy January 2011, Vol. 9 No. 1 pp 45-48  


2019 ◽  
Vol 1 (2) ◽  
pp. 41-45
Author(s):  
Suratno Suratno ◽  
Novidha Muji Rahayuningrum ◽  
Helmus Helmus

Alcohol consumption is often associated with the incidence of diabetes mellitus. This study aimed to examine fasting blood glucose levels and alcohol consumption in men in Mendawai, Palangka Raya, Central Kalimantan. The cross-sectional study design was carried out to asses fasting blood glucose levels on 20 male alcohol drinkers. Blood glucose assay was determined by an automated enzymatic colorimetric technique using Photometers (5010 V5+ Robert Riele). Determination of fasting blood glucose level using glucose oxidase and peroxidase (GOD-POD) method. This study found that 40% of alcohol drinker considered high fasting blood glucose level with an average level of 139.6 mg/dL. Twenty-five percent of alcohol drinkers regarded as low fasting blood glucose level with an average of 68.8 mg/dL. And 35% of drinkers have a normal level of fasting blood glucose with an average of 97.4 mg/dL


2014 ◽  
Vol 9 (1) ◽  
pp. 71
Author(s):  
Aprilya Roza Werdani ◽  
Triyanti Triyanti

Peningkatan kadar gula darah memicu peningkatan produksi hormon insulin yang erat hubungannya dengan diabetes melitus. Berdasarkan data Riskesdas, prevalensi diabetes melitus di Indonesia meningkat dari 1,1% (2007) menjadi 2,1% (2013). Penelitian ini bertujuan untuk mengetahui faktor dominan yang berhubungan dengan kadar gula darah puasa pegawai pemberdayaan masyarakat & keluarga dan pegawai sekretariat daerah Kota Depok. Desain penelitian yang digunakan adalah potong lintang dan melibatkan 105 sampel. Variabel independen penelitian meliputi karakteristik individu, asupan zat gizi, hipertensi, aktivitas fisik, status gizi dan pengetahuan gizi. Analisis data yang dilakukan adalah analisis univariat, analisis bivariat menggunakan uji korelasi dan uji beda dua mean, serta analisis multivariat menggunakan uji regresi linear ganda. Hasil penelitian menunjukkan bahwa rata-rata kadar gula darah puasa adalah 95,14±10,863 pada keseluruhan responden, sedangkan 94,07±11,55 mg/dl pada perempuan, dan 96,47±9,92 mg/dl pada laki-laki. Diabetes melitus (≥126 mg/dl) ditemukan sebesar 2,9% dan impaired fasting glucose (100-125 mg/dl) sebesar 22,9%. Berdasarkan hasil analisis bivariat, terdapat hubungan antara usia, asupan karbohidrat, dan aktivitas fisik dengan kadar gula darah puasa (p<0,05). Hasil analisis multivariat menunjukkan bahwa asupan karbohidrat merupakan faktor dominan yang berhubungan kadar gula darah puasa.Increased blood glucose levels lead to excess insulin secretion that is closely associated with diabetes mellitus. Based on Riskesdas, prevalence of diabetes mellitus in Indonesia has increased from 1,1% (2007) to 2,1% (2013). This study was aimed to find dominant factor associated with fasting blood glucose level. Cross sectional design were used to conduct this study and involved 105 samples. Independent variables in this study were individual characteristics, nutrients intake, history of hypertention, physical activities, nutritional status and nutritional knowledge. Bivariate analysis was performed by correlation test and two different test mean. Multivariate analysis was performed by multiple linear regression test. Result showed that the average of employees’ fasting blood glucose level is 95.14±10.863, 94.07 ± 11.55 mg/dL for woman and 96.47 ± 9.92 mg/dl for man. This study found 2.9% employees with diabetes mellitus (³126 mg/dl) and 22.9% employees with impaired fasting glucose (100-125 mg/dl). Result of bivariate analysis showed that associated between age, carbohydrate intake, physical activities with fasting blood glucose level. Result of multivariate analysis showed that carbohydrate intake was a dominant factor related to fasting blood glucose level. 


Author(s):  
Ahmad Tamaddoni ◽  
Morteza Alijanpour ◽  
Hassan Mahmoodi ◽  
Beniamin Miladi ◽  
Ali Bijani ◽  
...  

Background: Hyperglycemia is one of the most complications of corticosteroid and asparaginase during induction phase of chemotherapy in children suffering from acute lymphoblastic leukemia (ALL). This study was carried out to evaluate the incidence of hyperglycemia and associated risk factors during chemotherapy induction phase at Amirkola Children's Hospital. Materials and Methods: In this cross-sectional (retrospective) study, 150 children (mean age: 79.16±42.68 months) with ALL were evaluated (2000- 2011). Hyperglycemia was described as random blood glucose level more than 200mg/dl in patients less than 2 years old. In patients older than 2 years, fasting blood glucose level more than 110-125 mg/dl was considered as impaired glucose level and fasting blood glucose level more than 126 mg/dl was defined as diabetes mellitus. The data were analyzed using SPSS (version 18) and running chi square test, pearson Ccorrelation, and logistic regression. P-values less than0.05 was considered statistically significant. Results: Out of 150 children with ALL, 21 (14%) of them had hyperglycemia, but none of them had diabetic ketoacidosis. Hyperglycemia was significantly associated with gender (P=0.014) and age. (P=0.000) which was more likely in patients older than 10 years. The incidence of hyperglycemia was also related to BMI (P=0.000). Relapse rate for ALL was 14.7%, which was not significantly associated with hyperglycemia. Conclusion: Hyperglycemia was common and transient during induction phase of chemotherapy and it was correlated with age, sex, and weight.


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