Characterization of age-related changes in vestibular evoked myogenic potentials

2008 ◽  
Vol 17 (2-3) ◽  
pp. 93-98
Author(s):  
Dietmar Basta ◽  
Ingo Todt ◽  
Arne Ernst
Keyword(s):  
Muscle Activity ◽  
Age Groups ◽  
Tone Burst ◽  
Vestibular Evoked Myogenic Potentials ◽  
Burst Stimulation ◽  
Tonic Muscle ◽  
Age Related ◽  
Gender And Age ◽  
Dependent Relation ◽  
Age Related Changes

A tone-burst stimulation of 500 Hz seems to be clinically most appropriate to elicit vestibular evoked myogenic potentials (VEMPs) because those VEMPs can be recorded at the lowest stimulus intensity possible. However, little is known about gender and age-related changes of the amplitude in tone-burst (500 Hz) evoked VEMPs. The aim of the present paper was therefore to investigate the influence of gender and age on VEMP amplitude in relation to the tonic muscle activity. VEMPs of 64 healthy subjects were recorded ipsilaterally during air- or bone-conducted tone burst stimulation. The EMG of the tonically activated sternocleidomastoid muscle was recorded ipsilaterally with surface electrodes. Averages were taken for P1/N1 amplitudes of male and female volunteers within 3 different age groups. Although the amplitude decreased with increasing age the tonic activity was not significant different between the age groups. Consequently the relation between VEMP amplitude and tonic muscle activity decreased with increasing age. The normative values of the age-dependent relation between VEMP amplitude and tonic muscle activity were described by the 90% confidence interval of the individual values. Normative thresholds were calculated. Normal saccular receptor function could be diagnosed if the VEMP amplitude is above (or equal to) the normative value at a given tonic muscle activity and age. Normative data as described above are required to diagnose isolated saccular defects, which are indicative of a vestibular disorder.

Age-Related Changes in Vestibular Evoked Myogenic Potentials Using a Modified Blood Pressure Manometer Feedback Method

2010 ◽  
Vol 19 (2) ◽  
pp. 100-108 ◽  
Author(s):  
Brandon M. Tourtillott ◽  
John A. Ferraro ◽  
Ali Bani-Ahmed ◽  
Elaine Almquist ◽  
Nandini Deshpande
Keyword(s):  
Blood Pressure ◽  
Vestibular Evoked Myogenic Potentials ◽  
Age Related ◽  
Pressure Manometer ◽  
Feedback Method ◽  
Age Related Changes

scholarly journals Age-related changes in behavioural and emotional problems in Smith–Magenis syndrome measured with the Developmental Behavior Checklist

2020 ◽  
pp. 174462951990105 ◽  
Author(s):  
Heidi Elisabeth Nag ◽  
Terje Nærland
Keyword(s):  
Age Groups ◽  
Emotional Problems ◽  
Chromosome 17 ◽  
Adaptive Behaviour ◽  
Genetic Syndrome ◽  
Developmental Behavior ◽  
Age Related ◽  
Autism Symptomatology ◽  
Behavioural And Emotional Problems ◽  
Age Related Changes

Smith–Magenis syndrome (SMS) is a genetic syndrome most often caused by a deletion on chromosome 17 or more rarely by a mutation in the retinoic acid-induced 1 gene. The aim of this study was to investigate the Developmental Behavior Checklist (DBC) profile of persons with SMS and the associations between behavioural and emotional problems, age, gender, adaptive behaviour and autism symptomatology. Twenty-eight persons with SMS were represented by their parents in this study. DBC Total scores are reduced with age, but they still show a mean that is clearly above the cut-off of 46. The differences between the age groups <9 years and 9–17 years ( p = 0.024) and between the age groups <9 years and >18 years ( p = 0.007) are significant. We found a significant decrease in behavioural and emotional problems with age in SMS. We did not find a relationship between adapted behaviour and communication and behavioural and emotional problems.

scholarly journals Investigation of Age-Related Changes in the Skin Microbiota of Korean Women

2020 ◽  
Vol 8 (10) ◽  
pp. 1581
Author(s):  
Minseok Kim ◽  
Tansol Park ◽  
Jung Im Yun ◽  
Hye Won Lim ◽  
Na Rae Han ◽  
...  
Keyword(s):  
Age Groups ◽  
Alpha Diversity ◽  
Amplicon Sequencing ◽  
Diversity Indices ◽  
Rrna Gene ◽  
Korean Women ◽  
Skin Microbiota ◽  
Microbial Distribution ◽  
Age Related ◽  
Age Related Changes

The microbiota of human skin is influenced by host and environmental factors. To determine if chronological age influences the composition of the skin microbiota on the forehead and hands, 73 Korean women were sorted into one of three age groups: (1) 10–29 years (n = 24), (2) 30–49 years (n = 21), and (3) 50–79 years (n = 28). From the 73 women, 146 skin samples (two skin sites per person) were collected. 16S rRNA gene amplicon sequencing was then conducted to analyze the skin microbiota. The overall microbial distribution varied on the forehead but was similar on the hands across the three age groups. In addition, the composition of the skin microbiota differed between the forehead and hands. Commensal microbiota, such as Streptococcus, Staphylococcus, Cutibacterium, and Corynebacterium, which contribute to maintaining skin health via dominant occupation, were affected by increasing age on forehead and hand skin. Alpha diversity indices increased significantly with age on forehead skin. This study indicates that older people may be more susceptible to pathogenic invasions due to an imbalanced skin microbiota resulting from age-related changes. The results of our study may help develop new strategies to rebalance skin microbiota shifted during aging.

scholarly journals Age Related Changes in Weight of the Thymus Gland of Bangladeshi People

1970 ◽  
Vol 8 (1) ◽  
pp. 10-12
Author(s):  
Meherunnessa Begum ◽  
Uttam Kumar Paul ◽  
Md Jahangir Alam
Keyword(s):  
Related Problem ◽  
Immune Status ◽  
Regulatory Mechanism ◽  
Age Groups ◽  
The Body ◽  
Thymus Gland ◽  
Thymus Weight ◽  
Age Related ◽  
Key Words Thymus ◽  
Age Related Changes

Context: Thymus is intimately related to the immuno regulatory mechanism of the body, its weight in general as well as at different age in a particular population might also be related to the overall immune status of that population. Thus the knowledge of the weight of the thymus at different ages may be helpful in planning of the medical and surgical treatment of thymus related problem as well as dealing patients from immunologic aspects Objective: To measure the age related changes in weight of the thymus gland of Bangladeshi people Study design: A descriptive type of study Place and period of study: The study was carried out in the Department of Anatomy, IPGMR Dhaka from October 1996 to March 1997. Materials: 40 (forty) thymuses from Bangladeshi cadaver of either sex were taken for this study. Method: The collected samples were divided into four age groups ranged from still born to sixty years old individuals and comparative studies were done between different age groups. Result: The thymuses increased significantly in weight steadily through the increasing age groups from the still born babies to <16yrs and then declines through the age still higher. Conclusion: In the present study the weight of the thymus increases through the increasing age groups and then declined. Key words: Thymus; Weight DOI: 10.3329/bja.v8i1.6101 Bangladesh Journal of Anatomy January 2010, Vol. 8 No. 1 pp. 10-12

Effect of aging on tracheal mucociliary clearance in beagle dogs

1987 ◽  
Vol 62 (3) ◽  
pp. 1331-1334 ◽  
Author(s):  
S. L. Whaley ◽  
B. A. Muggenburg ◽  
F. A. Seiler ◽  
R. K. Wolff
Keyword(s):  
Young Adult ◽  
Gamma Camera ◽  
Mucociliary Clearance ◽  
Age Groups ◽  
Beagle Dogs ◽  
Velocity Measurements ◽  
Middle Aged ◽  
Age Related ◽  
Age Related Changes ◽  
Made In

Tracheal mucous velocity measurements were made in 24 beagle dogs in five age groups, using a gamma camera to detect movement of instilled 99mTc-macroaggregated albumin. Age groups were defined as immature (9–10 mo), young adult (2.8–3.0 yr), middle aged (6.7–6.9 yr), mature (9.6–9.8 yr), and aged dogs (13.6–16.2 yr). Mean velocities were 3.6 +/- 0.4 (SE) mm/min in the immature dogs, 9.7 +/- 0.6 mm/min in the young adults, 6.9 +/- 0.5 mm/min in the middle-aged dogs, 3.5 +/- 0.8 mm/min in the mature dogs, and 2.9 +/- 0.5 mm/min in the aged dogs. Tracheal mucous velocity was significantly (P less than 0.05) greater in the young adult and middle-aged groups compared with the immature, mature, and aged dogs. This pattern of age-related changes was noted to be similar to age-related changes described for certain pulmonary function measurements.

scholarly journals Age-related changes in muscle thickness and echo intensity of trunk muscles in healthy women: comparison of 20–60s age groups

2020 ◽  
Vol 120 (8) ◽  
pp. 1805-1814 ◽  
Author(s):  
Megumi Ota ◽  
Tome Ikezoe ◽  
Takehiro Kato ◽  
Hiroshige Tateuchi ◽  
Noriaki Ichihashi
Keyword(s):  
Age Groups ◽  
Muscle Thickness ◽  
Trunk Muscles ◽  
Echo Intensity ◽  
Healthy Women ◽  
Age Related ◽  
Age Related Changes

Gender and Age-Related Changes of Diffusion Tensor Imaging Parameters of Cervical Spinal Cord

2015 ◽  
Vol 15 (10) ◽  
pp. S91-S92
Author(s):  
Xiang Li ◽  
Tin Yan Chan ◽  
Kin Cheung Mak ◽  
Jason P. Cheung ◽  
Keith D. Luk ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Cervical Spinal Cord ◽  
Imaging Parameters ◽  
Age Related ◽  
Gender And Age ◽  
Age Related Changes

Maximal lactate steady state declines during the aging process

2003 ◽  
Vol 95 (6) ◽  
pp. 2576-2582 ◽  
Author(s):  
Craig O. Mattern ◽  
Margaret J. Gutilla ◽  
Darrin L. Bright ◽  
Timothy E. Kirby ◽  
Kenneth W. Hinchcliff ◽  
...  
Keyword(s):  
Steady State ◽  
Exercise Intensity ◽  
Citrate Synthase ◽  
Age Groups ◽  
Type I ◽  
Training Intensity ◽  
Maximal Lactate Steady State ◽  
Age Related ◽  
Competitive Cyclists ◽  
Age Related Changes

Increased participation of aged individuals in athletics warrants basic research focused on delineating age-related changes in performance variables. On the basis of potential age-related declines in aerobic enzyme activities and a shift in the expression of myosin heavy chain (MHC) isoforms, we hypothesized that maximal lactate steady-state (MLSS) exercise intensity would be altered as a function of age. Three age groups [young athletes (YA), 25.9 ± 1.0 yr, middle-age athletes (MA), 43.2 ± 1.0 yr, and older athletes (OA), 64.6 ± 2.7 yr] of male, competitive cyclists and triathletes matched for training intensity and duration were studied. Subjects performed a maximal O2 consumption (V̇o2 max) test followed by a series of 30-min exercise trials to determine MLSS. A muscle biopsy of the vastus lateralis was procured on a separate visit. There were differences ( P < 0.05) in V̇o2 max among all age groups (YA = 67.7 ± 1.2 ml · kg-1 · min-1, MA = 56.0 ± 2.6 ml · kg-1 · min-1, OA = 47.0 ± 2.6 ml · kg-1 · min-1). When expressed as a percentage of V̇o2 max, there was also an age-related decrease ( P < 0.05) in the relative MLSS exercise intensity (YA = 80.8 ± 0.9%, MA = 76.1 ± 1.4%, OA = 69.9 ± 1.5%). There were no significant age-related changes in citrate synthase activity or MHC isoform profile. The hypothesis is supported as there is an age-related decline in MLSS exercise intensity in athletes matched for training intensity and duration. Although type I MHC isoform, combined with age, is helpful in predicting ( r = 0.76, P < 0.05) relative MLSS intensity, it does not explain the age-related decline in MLSS.

Orienting Responses as a Function of Age and Task Complexity

1976 ◽  
Vol 42 (2) ◽  
pp. 543-553 ◽  
Author(s):  
Roger L. Greene
Keyword(s):  
Age Differences ◽  
Visual Stimulus ◽  
Task Complexity ◽  
Age Groups ◽  
Stimulus Onset ◽  
Age Related ◽  
Stimulus Content ◽  
Stimulus Offset ◽  
Age Related Changes ◽  
And Task

Age-related differences in the elicitation and habituation of orienting responses to the onset and offset of stimuli have been suggested by several authors. Electrodermal and cardiac orienting responses to the onset and offset of a visual stimulus were measured in three age groups (4 yr., 7 yr., and undergraduate). Each S made one of three judgments: non-signal (observe stimulus), content (color of stimulus), and duration (length of time stimulus presented). Few age differences were found in elicitation or habituation of orienting responses to stimulus onset or offset. There was a trend for elicitation of orienting responses to stimulus offset to be age-related, but the failure to find any other age-related changes made this difference somewhat questionable. Instructions as to the judgment to be made by S were the primary determinants of orienting responses to stimulus onset and offset across all age groups.

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