scholarly journals Age Related Changes in Weight of the Thymus Gland of Bangladeshi People

1970 ◽  
Vol 8 (1) ◽  
pp. 10-12
Author(s):  
Meherunnessa Begum ◽  
Uttam Kumar Paul ◽  
Md Jahangir Alam

Context: Thymus is intimately related to the immuno regulatory mechanism of the body, its weight in general as well as at different age in a particular population might also be related to the overall immune status of that population. Thus the knowledge of the weight of the thymus at different ages may be helpful in planning of the medical and surgical treatment of thymus related problem as well as dealing patients from immunologic aspects Objective: To measure the age related changes in weight of the thymus gland of Bangladeshi people Study design: A descriptive type of study Place and period of study: The study was carried out in the Department of Anatomy, IPGMR Dhaka from October 1996 to March 1997. Materials: 40 (forty) thymuses from Bangladeshi cadaver of either sex were taken for this study. Method: The collected samples were divided into four age groups ranged from still born to sixty years old individuals and comparative studies were done between different age groups. Result: The thymuses increased significantly in weight steadily through the increasing age groups from the still born babies to <16yrs and then declines through the age still higher. Conclusion: In the present study the weight of the thymus increases through the increasing age groups and then declined. Key words: Thymus; Weight DOI: 10.3329/bja.v8i1.6101 Bangladesh Journal of Anatomy January 2010, Vol. 8 No. 1 pp. 10-12

2020 ◽  
pp. 57-61
Author(s):  
V. M. Chertok ◽  
V. A. Nevzorova ◽  
A. K. Savchenko ◽  
O. V. Miroshnichenko ◽  
A. V. Laryushkina

Objective: Analysis of age-related changes of microcirculatory bed of bulbar conjunctiva.Methods: 46 individuals of both sexes, divided into 5 age groups according to WHO recommendations, were examined. Biomicroscopy of bulbar conjunctiva was performed using a non-mydriatic retinal camera TOPCON TRC-NW8F (Japan); the obtained images were processed with a mea‑ suring device of automated analysis system ImageScope (Leica, Germany).Results: The average diameter of arterioles, arterioleto-venule ratio (AVR) and specific density of capillaries were the largest, and the diameter of venules was the smallest among the subjects aged 18–44 years. The most sensitive indicators of the state of microcirculatory bed were AVR and the specific density of capillaries, the values of which in the group of 45–59-year-olds were 10–11% lower than in people aged 18–24 and 25–44 years. Differences in other indicators between people aged 18-24 and 45–59 years were not significant. Between the groups of 60–74 and 75–86-year-old participants of the study, pronounced differences (about 18%) were found only in the specific density of capillaries: compared with 18–24 and 45–59-year-olds, this indicator decreased by almost 1.5 times, AVR – only by a third, and changes in the average diameter of arterioles and venules did not exceed 9–12%. Elderly people more often demonstrated arteriolar spasm, their uneven caliber, avascular fields and other disorders of the structure of the micro‑ circulatory bed.Conclusions: As the body ages, in the microcirculatory bed of the bulbar conjunctiva, the number of atypical vascular formations increases, the diameter of the arterioles decreases, the AVR and the specific density of capillaries decrease, the diameter of the venules increases. 


1997 ◽  
Vol 85 (3_suppl) ◽  
pp. 1263-1271 ◽  
Author(s):  
Toshiaki Yanagida ◽  
Takaaki Asami

We investigated age-related changes in the distribution of body weight on soles of feet in 878 healthy subjects ranging from 5 to 80 years of age. By modifying Morton's Staticometer, we constructed an instrument for measuring body-weight distribution over three areas of soles of the feet, the big toe (inner forefoot), the other four toes combined (outer forefoot) and the heels for both feet, thus a total of six areas. The weights in the six areas were recorded at the completion of nine selected actions and postures. We observed that for inhaling and exhaling standing postures, generally younger subjects had a ratio close to 1:2:3 for weights recorded for the inner toe:outer toes:heels as observed by Morton, but elderly subjects had a smaller value than 3 for the heel. The body-weight distribution tended to shift from heels to outer toes across age groups, which was more distinctly observed in women than in men.


Author(s):  
A. E. Chernikova ◽  
Yu. P. Potekhina

Introduction. An osteopathic examination determines the rate, the amplitude and the strength of the main rhythms (cardiac, respiratory and cranial). However, there are relatively few studies in the available literature dedicated to the influence of osteopathic correction (OC) on the characteristics of these rhythms.Goal of research — to study the influence of OC on the rate characteristics of various rhythms of the human body.Materials and methods. 88 adult osteopathic patients aged from 18 to 81 years were examined, among them 30 men and 58 women. All patients received general osteopathic examination. The rate of the cranial rhythm (RCR), respiratory rate (RR) heart rate (HR), the mobility of the nervous processes (MNP) and the connective tissue mobility (CTM) were assessed before and after the OC session.Results. Since age varied greatly in the examined group, a correlation analysis of age-related changes of the assessed rhythms was carried out. Only the CTM correlated with age (r=–0,28; p<0,05) in a statistically significant way. The rank dispersion analysis of Kruskal–Wallis also showed statistically significant difference in this indicator in different age groups (p=0,043). With the increase of years, the CTM decreases gradually. After the OC, the CTM, increased in a statistically significant way (p<0,0001). The RCR varied from 5 to 12 cycles/min in the examined group, which corresponded to the norm. After the OC, the RCR has increased in a statistically significant way (p<0,0001), the MNP has also increased (p<0,0001). The initial heart rate in the subjects varied from 56 to 94 beats/min, and in 15 % it exceeded the norm. After the OC the heart rate corresponded to the norm in all patients. The heart rate and the respiratory rate significantly decreased after the OC (р<0,0001).Conclusion. The described biorhythm changes after the OC session may be indicative of the improvement of the nervous regulation, of the normalization of the autonomic balance, of the improvement of the biomechanical properties of body tissues and of the increase of their mobility. The assessed parameters can be measured quickly without any additional equipment and can be used in order to study the results of the OC.


2020 ◽  
pp. 174462951990105 ◽  
Author(s):  
Heidi Elisabeth Nag ◽  
Terje Nærland

Smith–Magenis syndrome (SMS) is a genetic syndrome most often caused by a deletion on chromosome 17 or more rarely by a mutation in the retinoic acid-induced 1 gene. The aim of this study was to investigate the Developmental Behavior Checklist (DBC) profile of persons with SMS and the associations between behavioural and emotional problems, age, gender, adaptive behaviour and autism symptomatology. Twenty-eight persons with SMS were represented by their parents in this study. DBC Total scores are reduced with age, but they still show a mean that is clearly above the cut-off of 46. The differences between the age groups <9 years and 9–17 years ( p = 0.024) and between the age groups <9 years and >18 years ( p = 0.007) are significant. We found a significant decrease in behavioural and emotional problems with age in SMS. We did not find a relationship between adapted behaviour and communication and behavioural and emotional problems.


2020 ◽  
Vol 8 (10) ◽  
pp. 1581
Author(s):  
Minseok Kim ◽  
Tansol Park ◽  
Jung Im Yun ◽  
Hye Won Lim ◽  
Na Rae Han ◽  
...  

The microbiota of human skin is influenced by host and environmental factors. To determine if chronological age influences the composition of the skin microbiota on the forehead and hands, 73 Korean women were sorted into one of three age groups: (1) 10–29 years (n = 24), (2) 30–49 years (n = 21), and (3) 50–79 years (n = 28). From the 73 women, 146 skin samples (two skin sites per person) were collected. 16S rRNA gene amplicon sequencing was then conducted to analyze the skin microbiota. The overall microbial distribution varied on the forehead but was similar on the hands across the three age groups. In addition, the composition of the skin microbiota differed between the forehead and hands. Commensal microbiota, such as Streptococcus, Staphylococcus, Cutibacterium, and Corynebacterium, which contribute to maintaining skin health via dominant occupation, were affected by increasing age on forehead and hand skin. Alpha diversity indices increased significantly with age on forehead skin. This study indicates that older people may be more susceptible to pathogenic invasions due to an imbalanced skin microbiota resulting from age-related changes. The results of our study may help develop new strategies to rebalance skin microbiota shifted during aging.


1987 ◽  
Vol 62 (3) ◽  
pp. 1331-1334 ◽  
Author(s):  
S. L. Whaley ◽  
B. A. Muggenburg ◽  
F. A. Seiler ◽  
R. K. Wolff

Tracheal mucous velocity measurements were made in 24 beagle dogs in five age groups, using a gamma camera to detect movement of instilled 99mTc-macroaggregated albumin. Age groups were defined as immature (9–10 mo), young adult (2.8–3.0 yr), middle aged (6.7–6.9 yr), mature (9.6–9.8 yr), and aged dogs (13.6–16.2 yr). Mean velocities were 3.6 +/- 0.4 (SE) mm/min in the immature dogs, 9.7 +/- 0.6 mm/min in the young adults, 6.9 +/- 0.5 mm/min in the middle-aged dogs, 3.5 +/- 0.8 mm/min in the mature dogs, and 2.9 +/- 0.5 mm/min in the aged dogs. Tracheal mucous velocity was significantly (P less than 0.05) greater in the young adult and middle-aged groups compared with the immature, mature, and aged dogs. This pattern of age-related changes was noted to be similar to age-related changes described for certain pulmonary function measurements.


2020 ◽  
Vol 120 (8) ◽  
pp. 1805-1814 ◽  
Author(s):  
Megumi Ota ◽  
Tome Ikezoe ◽  
Takehiro Kato ◽  
Hiroshige Tateuchi ◽  
Noriaki Ichihashi

2018 ◽  
Vol 31 (6) ◽  
pp. 537-555 ◽  
Author(s):  
Jennifer L. Campos ◽  
Graziella El-Khechen Richandi ◽  
Babak Taati ◽  
Behrang Keshavarz

Percepts about our body’s position in space and about body ownership are informed by multisensory feedback from visual, proprioceptive, and tactile inputs. The Rubber Hand Illusion (RHI) is a multisensory illusion that is induced when an observer sees a rubber hand being stroked while they feel their own, spatially displaced, and obstructed hand being stroked. When temporally synchronous, the visual–tactile interactions can create the illusion that the rubber hand belongs to the observer and that the observer’s real hand is shifted in position towards the rubber hand. Importantly, little is understood about whether these multisensory perceptions of the body change with older age. Thus, in this study we implemented a classic RHI protocol (synchronous versus asynchronous stroking) with healthy younger (18–35) and older (65+) adults and measured the magnitude of proprioceptive drift and the subjective experience of body ownership. As an adjunctive objective measure, skin temperature was recorded to evaluate whether decreases in skin temperature were associated with illusory percepts, as has been shown previously. The RHI was observed for both age groups with respect to increased drift and higher ratings of ownership following synchronous compared to asynchronous stroking. Importantly, no effects of age and no interactions between age and condition were observed for either of these outcome measures. No effects were observed for skin temperature. Overall, these results contribute to an emerging field of research investigating the conditions under which age-related differences in multisensory integration are observed by providing insights into the role of visual, proprioceptive, and tactile inputs on bodily percepts.


2003 ◽  
Vol 95 (6) ◽  
pp. 2576-2582 ◽  
Author(s):  
Craig O. Mattern ◽  
Margaret J. Gutilla ◽  
Darrin L. Bright ◽  
Timothy E. Kirby ◽  
Kenneth W. Hinchcliff ◽  
...  

Increased participation of aged individuals in athletics warrants basic research focused on delineating age-related changes in performance variables. On the basis of potential age-related declines in aerobic enzyme activities and a shift in the expression of myosin heavy chain (MHC) isoforms, we hypothesized that maximal lactate steady-state (MLSS) exercise intensity would be altered as a function of age. Three age groups [young athletes (YA), 25.9 ± 1.0 yr, middle-age athletes (MA), 43.2 ± 1.0 yr, and older athletes (OA), 64.6 ± 2.7 yr] of male, competitive cyclists and triathletes matched for training intensity and duration were studied. Subjects performed a maximal O2 consumption (V̇o2 max) test followed by a series of 30-min exercise trials to determine MLSS. A muscle biopsy of the vastus lateralis was procured on a separate visit. There were differences ( P < 0.05) in V̇o2 max among all age groups (YA = 67.7 ± 1.2 ml · kg-1 · min-1, MA = 56.0 ± 2.6 ml · kg-1 · min-1, OA = 47.0 ± 2.6 ml · kg-1 · min-1). When expressed as a percentage of V̇o2 max, there was also an age-related decrease ( P < 0.05) in the relative MLSS exercise intensity (YA = 80.8 ± 0.9%, MA = 76.1 ± 1.4%, OA = 69.9 ± 1.5%). There were no significant age-related changes in citrate synthase activity or MHC isoform profile. The hypothesis is supported as there is an age-related decline in MLSS exercise intensity in athletes matched for training intensity and duration. Although type I MHC isoform, combined with age, is helpful in predicting ( r = 0.76, P < 0.05) relative MLSS intensity, it does not explain the age-related decline in MLSS.


1976 ◽  
Vol 42 (2) ◽  
pp. 543-553 ◽  
Author(s):  
Roger L. Greene

Age-related differences in the elicitation and habituation of orienting responses to the onset and offset of stimuli have been suggested by several authors. Electrodermal and cardiac orienting responses to the onset and offset of a visual stimulus were measured in three age groups (4 yr., 7 yr., and undergraduate). Each S made one of three judgments: non-signal (observe stimulus), content (color of stimulus), and duration (length of time stimulus presented). Few age differences were found in elicitation or habituation of orienting responses to stimulus onset or offset. There was a trend for elicitation of orienting responses to stimulus offset to be age-related, but the failure to find any other age-related changes made this difference somewhat questionable. Instructions as to the judgment to be made by S were the primary determinants of orienting responses to stimulus onset and offset across all age groups.


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