scholarly journals Reactive arthritis and erythema nodosum after gastrointestinal infections caused by Yersinia enterocolitica and Yersinia pseudotuberculossis

2020 ◽  
pp. 77-85
Author(s):  
Waldemar Rastawicki

After gastrointestinal infection with Y. enterocolitica and Y. pseudotuberculosis, some patients may experience reactive arthritis and erythema nodosum. In the etiopathogenesis of these autoimmune complications, in addition to infectious agents, genetic factors, gender and age of the patients also play a role. In the study of the etiology of reactive arthritis and erythema nodosum after gastrointestinal infection, it is useful to investigate in the serum of patients specific antibodies for selected intestinal pathogens, including Yersinia antigens.

1984 ◽  
Vol 29 (3) ◽  
pp. 197-199 ◽  
Author(s):  
W. D. Neithercut ◽  
M. A. Hudson ◽  
C. C. Smith

Erythema nodosum and seronegative arthritis associated with diarrhoea was previously regarded as implying the presence of inflammatory bowel disease. Recently, however, erythema nodosum has been described as a sequel to diarrhoea caused by infection with Salmonella typhimurium, Yersinia enterocolitica and Campylobacter jejuni. We report two patients in whom erythema nodosum and reactive arthritis followed acute Shigella flexneri gastroenteritis, a rare association.


1999 ◽  
Vol 55 (12) ◽  
pp. 913-915
Author(s):  
SCHUTGENS REG ◽  
WERNER A ◽  
DE GRAAF P

1985 ◽  
Vol 4 (4) ◽  
pp. 487-487 ◽  
Author(s):  
J. Roudier ◽  
H. De Montclos ◽  
D. Thouvenot ◽  
J. J. Chomel ◽  
F. N. Guillermet ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Golnar Rahimzadeh ◽  
Majid Saeedi ◽  
Mahmood Moosazadeh ◽  
Seyyed Mohammad Hassan Hashemi ◽  
Amirhossein Babaei ◽  
...  

AbstractThe therapeutic effectiveness of a chitosan encapsulated bacteriophage cocktail as a smart biocontrol agent was evaluated in this study to be used as a preventative and treatment option for gastrointestinal infections. To evaluate the effect of the bacteriophage formulation on the treatment of gastrointestinal infection, rats were infected with Salmonella enterica, Shigella flexneri, and Escherichia coli. The rats were weighed and their stools cultured. The results showed that the group which had the chitosan encapsulated bacteriophage cocktail did not lose weight after 3 days and had significantly lower group weight changes. Weight loss was significant in the rats that had cefixime administered instead. Positive cultured stools were reduced after 4 days compared to 2 days in the treated group with the chitosan encapsulated bacteriophage cocktail. The chitosan encapsulated bacteriophage cocktail can therefore be effective in the treatment of gastrointestinal infections.


1934 ◽  
Vol 60 (1) ◽  
pp. 19-35 ◽  
Author(s):  
Kenneth Goodner

The power of specific antipneumococcus serum to protect rabbits against infection with Type I Pneumococcus has been studied with reference to the capacity of the animal to utilize the specific antibodies. Under conditions ensuring relatively controlled genetic factors it was found that heavier animals and those with high white blood cell counts are much better able to utilize the passively conferred immune principles. The interrelationships of the extrinsic and intrinsic factors responsible for immunity have been discussed.


2021 ◽  
Vol 12 ◽  
Author(s):  
Philip A. Karlsson ◽  
Eva Tano ◽  
Cecilia Jernberg ◽  
Rachel A. Hickman ◽  
Lionel Guy ◽  
...  

The foodborne pathogen Yersinia enterocolitica causes gastrointestinal infections worldwide. In the spring of 2019, the Swedish Public Health Agency and Statens Serum Institut in Denmark independently identified an outbreak caused by Yersinia enterocolitica 4/O:3 that after sequence comparison turned out to be a cross-border outbreak. A trace-back investigation suggested shipments of fresh prewashed spinach from Italy as a common source for the outbreak. Here, we determined the genome sequences of five Y. enterocolitica clinical isolates during the Swedish outbreak using a combination of Illumina HiSeq short-read and Nanopore Technologies’ MinION long-read whole-genome sequencing. WGS results showed that all clinical strains have a fully assembled chromosome of approximately 4.6 Mbp in size and a 72-kbp virulence plasmid; one of the strains was carrying an additional 5.7-kbp plasmid, pYE-tet. All strains showed a high pathogen probability score (87.5%) with associated genes for virulence, all of which are closely related to an earlier clinical strain Y11 from Germany. In addition, we identified a chromosomally encoded multidrug-resistance cassette carrying resistance genes against chloramphenicol (catA1), streptomycin (aadA1), sulfonamides (sul1), and a mercury resistance module. This chromosomally encoded Tn2670 transposon has previously been reported associated with IncFII plasmids in Enterobacteriaceae: a Shigella flexneri clinical isolate from Japan in 1950s, a Klebsiella pneumoniae outbreak from Australia in 1997, and Salmonella enterica serovar Typhimurium. Interestingly, we identified an additional 5.7-kbp plasmid with tetB (encoding an ABC transporter), Rep, and its own ORI and ORIt sites, sharing high homology with small tetB-Rep plasmids from Pasteurellaceae. This is the first time that Tn2670 and Pasteurellaceae plasmids have been reported in Y. enterocolitica. Taken together, our study showed that the Swedish Y. enterocolitica outbreak strains acquired multi-antibiotic and metal-resistance genes through horizontal gene transfer, suggesting a potential reservoir of intraspecies dissemination of multidrug-resistance genes among foodborne pathogens. This study also highlights the concern of food-chain contamination of prewashed vegetables as a perpetual hazard against public health.


2021 ◽  
Author(s):  
Kamyar Shokraee ◽  
Soroush Moradi ◽  
Tahereh Eftekhari ◽  
Rasoul Shajari ◽  
Maryam Masoumi

Abstract Background: SARS-COV-2, first reported in December 2019, usually presents with respiratory symptoms but can have various other manifestations and sequelae. One of the rare complications of COVID-19 infection is Reactive Arthritis. This complication is more likely to occur following sexually transmitted or gastrointestinal infection.Case presentation: Herein, we report a 58 years old woman hospitalized following COVID-19 infection and was discharged after a week. She consequently presented to the clinic ten days after her discharge, complaining of walking difficulties and radiating pain in her right hip. After ultrasound and MRI, she was diagnosed with reactive arthritis inflammation in the hip’s neck. Other known microorganisms responsible for reactive arthritis were ruled out before attributing it to the earlier COVID-19 infection. She reached remission after being treated using a combination of indomethacin and depot methyl-prednisolone for 14 days. Conclusion: To our knowledge, this is the first case of reactive arthritis caused by SARS-COV-2 in the hip. Further attention should be paid to symptoms occurring after an episode of infection with COVID-19 in order to expand our understanding of the disease and the symptoms with which it can manifest.


2017 ◽  
Author(s):  
Marcia B Goldberg ◽  
Molly Paras

Gastrointestinal infections, which present with acute diarrhea, sometimes accompanied by vomiting, are an extremely common medical complaint, with an annual incidence of 0.6 illnesses per person. Transmission can occur from animals to person, from person to person, or by the ingestion of contaminated foodstuffs. In the United States, more than 90% of cases are caused by viruses, with norovirus being by far the most common. Common among bacterial causes of acute gastrointestinal infection are Salmonella, Campylobacter, Shigella, Shiga toxin–producing Escherichia coli, Vibrio, Yersinia, and Clostridium difficile. These infections are typically self-limited, but depending on the etiologic agent and characteristics of the host, antibiotic therapy may be indicated. Certain gastrointestinal infections are associated with significant complications, including reactive arthritis, Guillain-Barré syndrome, or septicemia. This review contains 4 figures, 7 tables, and 60 references. Key words: Campylobacter, Escherichia coli, Guillain-Barré syndrome, reactive arthritis, Shiga toxin, Shigella, Vibrio, Yersinia


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