PLASMA ATHEROGENIC INDEX IS AN INDEPENDENT INDICATOR AND PROGNOSTIC VALUE IN RAYNAUD’S PHENOMENON?
Objective: Raynaud’s phenomenon (RP) is characterized by cold induced temporary ischaemia of the fingers or toes and an inflammatory autoimmune disease of connective tissues. Plasma atherogenic index (PAI) is a valuable marker for the cardiovascular disease and cardiac risk. The aim of this study was to evaluate the role and clinical use of PAI in RP patients. Materials and Methods: In this retrospective-cohort study, we examined the clinical value count blood cells in 55 patients with RP and 14 clinical controls admitted Konya Training and Research Hospital Department of Cardiovascular Surgery between January 2016-March 2019 were investigated retrospectively screened. PAI was measured as a logarithmic value of triglyceride to high-density cholesterol ratio. PAI levels <0.11 is accepted as low risk, 0,11-0,21 intermediate risk, and 0.21 >increased risk. PAI was measured as a logarithmic value of triglyceride to high-density cholesterol ratio. The lipid and other biochemical parameters of patient and control groups were examined and measured. Results: The study consisted of 29 females (42.03%) and 40 males (57.97%). There was a significant difference between differences between PAI level groups. There was no significant difference in PAI results between genders (p>0.355).We also found disagreement in biochemical parameters and PAI between controls and patients. Conclusion: When we evaluated PAI in the patients with RP and controls, it was determined that there was no significant difference in either parameter. However, PAI levels have showed that significant elevated between groups so It can be a simple, economic and non invasive marker to identify for future studies. Keywords: Raynaud’s phenomenon, Plasma atherogenic index, Blood lipid components