scholarly journals Hasil BERA & TEOAE dengan kadar HbA1c pada pasien Diabetes Melitus tipe-2

2019 ◽  
Vol 49 (1) ◽  
pp. 12
Author(s):  
Novi Primadewi ◽  
Hadi Sudrajad ◽  
Eka Prasetya
Keyword(s):  
Hearing Loss ◽  
Significant Relationship ◽  
Hba1c Level ◽  
Cross Sectional Study ◽  
T Test ◽  
Sectional Study ◽  
Cross Sectional ◽  
Type 2 Dm ◽  
Diabetes Melitus

Latar belakang: Neuropati adalah salah satu komplikasi yang paling sering dari Diabetes Melitus(DM) tipe 2. Disamping neuropati perifer dan otonom, pasien dengan DM tipe 2 juga dapat menderitagangguan pendengaran tipe sensorineural hearing loss (SNHL) pada frekuensi tinggi. Pada studi inihubungan HbA1c dengan hasil pemeriksaan brainstem evoked response audiometry (BERA) dan transient evoked otoacoustic emissions (TEOAE) digunakan untuk mendeteksi neuropati akustik dan sentral pada pasien DM tipe 2. Tujuan: Untuk mengetahui hubungan kadar HbA1c pada DM tipe 2 dengan masa laten gelombang BERA dan respon TEOAE. Metode: Desain penelitian cross sectional study, dilakukan dari Maret 2018 hingga jumlah sample terpenuhi. Penelitian dimulai dengan mengidentifikasi pasien DM tipe 2 dengan profil kadar HbA1c, kemudian dilanjutkan dengan pemeriksaan TEOAE dan BERA. Hasil: Dari hasil pemeriksaan BERA terdapat hubungan signifikan antara HbA1c dengan masa laten gelombang BERA di intensitas 70 dB dan 80 dB kecuali latensi antar-puncak I-V, tetapi tidak berhubungan signifikan pada intensitas 90 dB. Didapatkan pada pemeriksaan TEOAE di telinga kanan kadar HbA1c berhubungan dengan hasil pemeriksaan TEOAE kategori refer rata-rata 8,67+1,14%, sedangkan pasien dengan hasil pemeriksaan TEOAE kategori pass rata-rata 7,73+0,95%. Hasil uji t test didapatkan nilai p=0,021 (p<0,05). TEOAE di telinga kiri kategori refer rata-rata 8,82+1,09%, sedangkan pasien dengan hasil pemeriksaan TEOAE kategori pass rata-rata 7,66+0,88%. Hasil uji t test didapatkan nilai p=0,003 (p<0,05). Kesimpulan: Terdapat hubungan yang signifikan secara statistik antara kadar HbA1c dengan hasil pemeriksaan gelombang BERA dan TEOAE. Background: Neuropathy is complication of type 2 diabetes mellitus (DM). Besides peripheraland autonomic neuropathy, patients with type 2 DM may also have sensorineural hearing loss at highfrequency. In this study the association of HbA1c level with the results of BERA and TEOAE tests was used to detect acoustic and central neuropathy in type 2 DM patients. Objective: To find out the relationship of HbA1c level in type 2 DM with BERA and TEOAE. Method: Research design cross sectional study, conducted from March 2018 until the number of samples fulfilled. The study began by identifying patients with type 2 DM with the HbA1c profile, followed by TEOAE and BERA examinations. Result: There was a significant relationship between HbA1c and the latent period of waves at the intensity of 70 dB and 80 dB except on the interpeak I-V latency, but not significantly related to the 90 dB intensity. Results of TEOAE test in the right ear: the average levels of HbA1c with refer category results on TEOAE test was 8.67+1.14 %, whereas patients with pass category results on TEOAE was 7.73+0.95 %. The result of t test value was p=0.021 (p<0.05). TEOAE on the left ear: average refer category 8.82+1.09%, whereas patients with TEOAE examination results in the mean pass category 7.66+0.88%. The result of t test value was p=0.003 (p<0.05). Conclusion: There was a statistical significant relationship between HbA1clevel and BERA and TEOAE.

scholarly journals Diabetic kidney disease in patients with type 2 diabetes mellitus: a cross-sectional study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Randa I. Farah ◽  
Mohammed Q. Al-Sabbagh ◽  
Munther S. Momani ◽  
Asma Albtoosh ◽  
Majd Arabiat ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Kidney Disease ◽  
Diabetic Kidney Disease ◽  
Laboratory Data ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Diabetic Kidney ◽  
Type 2 Dm

Abstract Aim Diabetic kidney disease (DKD) is a major long-term complication of diabetes mellitus (DM). Given the paucity of data on DKD in Jordan, we aimed to evaluate the prevalence, characteristics and correlates of DKD in Jordanian patients with type 2 DM. Methods This cross-sectional study included 1398 adult patients with type 2 DM who sought medical advice in the endocrinology clinic between March and September 2019. Demographic, clinical and laboratory data were reviewed. DKD was defined as reduced eGFR, and/or albuminuria. Three regression models were constructed to identify factors associated with CKD stages, albuminuria and DKD. Results Overall, 701 (50.14%) patients had DKD, with a median age of 59.71 ± 11.36  years. Older age, high triglycerides, and low high-density lipoprotein were associated with DKD (multivariable odds ratio [OR]: 1.02, 95% confidence interval [CI]: 1.01–1.03, p < 0.01; OR: 1.1, 95% CI: 1.01–1.2; and OR: 0.98, 95% CI: 0.97–0.99, p < 0.01 respectively). Metformin and renin-angiotensin system blockers were negatively associated with albuminuria and chronic kidney disease stages (p < 0.01). Conclusion Our study demonstrated that approximately one half of patients with type 2 DM had DKD. Further studies are necessary to understand this high prevalence and the underlying factors. Future research are needed to assess implementing targeted community-based intervention.

scholarly journals Relationship between Blood HbA1c Level and Decayed Teeth in Patients with Type 2 Diabetes: A Cross-sectional Study

2018 ◽  
Vol 60 (2) ◽  
pp. 89-96
Author(s):  
Seitaro Suzuki ◽  
Koichi Yoshino ◽  
Atsushi Takayanagi ◽  
Yoichi Ishizuka ◽  
Ryouichi Satou ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Hba1c Level ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Low Levels of Usual Physical Activity Are Associated with Higher 24 h Blood Pressure in Type 2 Diabetes Mellitus in a Cross-Sectional Study

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Alessandra Teixeira Neto Zucatti ◽  
Tatiana Pedroso de Paula ◽  
Luciana Verçoza Viana ◽  
Rafael DallAgnol ◽  
Felipe Vogt Cureau ◽  
...  
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Type 2 Dm ◽  
Low Levels

The aim of this study is to evaluate the association between usual physical activity and 24 h blood pressure (BP) profile in people with type 2 diabetes mellitus (DM). This is a cross-sectional study of 151 participants with type 2 DM. Usual physical activity was assessed by step counting and self-reported questionnaire. BP was measured in office and by 24 h ambulatory BP monitoring (ABPM; 24 h, daytime and nighttime). Mean participant age was 61.1 ± 8.4 years, 64% was women, and mean duration of diabetes was 14.3 ± 8.5 years. Ninety-two percent of participants had hypertension, and office BP was 138 ± 18/78 ± 10 mmHg. Inverse correlations were observed between step count and 24 h BP (systolic, r=−0.186; p=0.022), daytime BP (systolic, r=−0.198; p=0.015), and nighttime BP (pulse pressure, r=−0.190; p=0.019). People were categorized into tertiles of daily step count, and the 1st tertile had higher 24 h systolic BP, daytime systolic BP, daytime mean BP, and daytime systolic BP load than those in the other tertiles, even after adjusting for age and HbA1c. Participants with type 2 DM and low levels of physical activity exhibit higher 24 h and daytime systolic ambulatory BP values as compared with those who performed more steps per day, even after adjustments for confounding factors.

scholarly journals Adherencia terapéutica y control metabólico en pacientes con diabetes mellitus tipo 2 / adherence and metabolic control in patients with type 2 diabetes mellitus in a hospital of medellin (colombia), 2011

2014 ◽  
Vol 14 (1) ◽  
pp. 44-50
Author(s):  
Lina María Martínez Sánchez ◽  
Gloria Inés Martínez Domínguez ◽  
María de los angeles Rodríguez Gázquez ◽  
Camilo andrés Agudelo Vélez ◽  
Juan Guillermo Jiménez Jiménez ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Therapeutic Adherence ◽  
Type 2 Dm ◽  
Patients With Diabetes ◽  
Apoyo Social ◽  
The Relationship

Objetivo:Explorar la relación entre la adherencia terapéutica y el control metabólicoen pacientes con Diabetes Mellitus tipo 2 (DM-2), que consultaron a una instituciónhospitalaria en Medellín-Colombia.Materiales y métodos:Estudio transversal. Lamuestra estuvo constituida por personas con 18 y más años, con diagnóstico de DM-2•PHVHVTXHILUPDURQHOFRQVHQWLPLHQWRLQIRUPDGR(OPXHVWUHRIXHQRSUREDELOtVWLFRmuestra por conveniencia. Se aplicaron las escalas Summary of Diabetes Self-CareActivities para valorar adherencia terapéutica y Duke-Unc para evaluar apoyo social.La hemoglobina glicosilada (HbA1c) fue procesada por el método inmunoturbidimé-trico de inhibición en el Equipo Cobas C-501. Se asumió como “control metabólicoadecuado” un valor de HbA1c < al 7%. Se utilizó el programa SPSS versión 19.0 parael análisis.Resultados:De los 70 pacientes estudiados: el 66% son mujeres, el 76%tiene Hipertensión arterial, el 70% tiene dislipidemias y el 16% fuma. Además, el 59%HVLQVXOLQRGHSHQGLHQWHHOWLHQH+E$F•HOQRWLHQHDSRRVRFLDO/RVfactores con mayor proporción de adherencia fueron: medicación (79%), cuidado depies (71%). Mientras que los más bajos fueron: autocontrol glicémico (32%) y ejercicio(28%). La HbA1c se correlacionó significativamente (p<0.05) con adherencia a dieta,autocontrol de glicemia, cuidado de pies, apoyo social y género.Conclusiones:Laadherencia terapéutica estuvo asociada al control metabólico en pacientes con DM-2. Objective: Explore the relationship between the therapeutic adherence and metaboliccontrol in patients with Diabetes Mellitus type 2 (DM-2), which consulted to a hospitalinstitution in Medellin-Colombia. Materials and Methods: Cross-sectional study. The

scholarly journals Alterations of Retinal Pigment Epithelium–Photoreceptor Complex in Patients with Type 2 Diabetes Mellitus without Diabetic Retinopathy: A Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Zheren Xia ◽  
Hao Chen ◽  
Suilian Zheng
Keyword(s):  
Diabetes Mellitus ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Cross Sectional Study ◽  
Healthy Controls ◽  
Sectional Study ◽  
Cross Sectional ◽  
Type 2 Dm ◽  
Sd Oct

Aim. A cross-sectional study was performed to examine the alterations of the retinal pigment epithelium– (RPE–) photoreceptor complex layer in type 2 diabetes mellitus (DM) without diabetic retinopathy (DR), using spectral-domain optical coherence tomography (SD-OCT). Methods. Patients with type 2 DM without DR and healthy controls without DM were recruited. All participants underwent examinations including SD-OCT. The thickness measurements of the retinal neural layers were calculated after automatic segmentation. An independent-sample t-test was used to compare the means of the thickness of retinal neural layers in patients with DM and healthy controls. Results. Sixty-seven eyes from 67 patients with DM and 30 eyes from 30 healthy controls were included in this study. No significant differences were found in age (P = 0.601), gender (P = 0.560), axial length (P = 0.414), best-corrected visual acuity (P = 0.963), or intraocular pressure (P = 0.112) between the two groups. There were significant increases in the hemoglobin A1c value (P < 0.001) and mean thicknesses of the RPE–photoreceptor complex layer in the foveal area (P = 0.027) and paracentral area (P = 0.001) in the DM group compared to the control group, whereas the thickness of the retinal nerve fiber and ganglion cell layers in the foveal and paracentral areas between the two groups showed no significant differences. Conclusion. Lesions in the RPE–photoreceptor complex are present without vascular abnormalities, which may precede the alterations of ganglion cells in patients with type 2 DM.

scholarly journals Inconvenient relationship of haemoglobin A1c level with endothelial function in type 2 diabetes in a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e045415
Author(s):  
Takayuki Yamaji ◽  
Takahiro Harada ◽  
Yu Hashimoto ◽  
Yuji Takaeko ◽  
Masato Kajikawa ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Hba1c Level ◽  
Cross Sectional Study ◽  
Antidiabetic Drugs ◽  
Haemoglobin A1c ◽  
Sectional Study ◽  
Cross Sectional ◽  
Relationship Of ◽  
Shaped Pattern

ObjectiveThe aim of this study was to determine the relationship of haemoglobin A1c (HbA1c) level with flow-mediated vasodilation (FMD) and nitroglycerine-induced vasodilation (NID) in patients with type 2 diabetes.DesignCross-sectional study.Setting22 university hospitals and affiliated clinics in Japan.Participants1215 patients with type 2 diabetes including 349 patients not taking antidiabetic drugs.MeasuresWe evaluated FMD and HbA1c level. All patients were divided into four groups based on HbA1c level: <6.5%, 6.5%–6.9%, 7.0%–7.9% and ≥8.0%.ResultsAn inverted U-shaped pattern of association between HbA1c level and FMD was observed at the peak of HbA1c of about 7%. FMD was significantly smaller in the HbA1c <6.5% group than in the HbA1c 6.5%–6.9% group and HbA1c 7.0%–7.9% group (p<0.001 and p<0.001), and FMD values were similar in the HbA1c <6.5% group and HbA1c ≥8.0% group. There were no significant differences in NID values among the four groups. After adjustments for confounding factors, FMD was significantly smaller in the HbA1c <6.5% group than in the HbA1c 6.5%–6.9% and HbA1c 7.0%–7.9% group (p=0.002 and p=0.04). In patients not taking antidiabetic drugs, FMD was also significantly smaller in the HbA1c <6.5% group than in the HbA1c 6.5%–6.9% group and HbA1c 7.0%–7.9% group (p<0.001 and p=0.02), and there were no significant differences in NID values among the four groups.ConclusionsThese findings suggest that there is an inverted U-shaped pattern of association between FMD and HbA1c and that a low HbA1c level of <6.5% is associated with endothelial dysfunction.Trial registration numberUMIN000012950, UMIN000012951, UMIN000012952 and UMIN000003409.

scholarly journals HUBUNGAN HEALTH LOCUS OF CONTROL DENGAN KEPATUHAN TERAPI INSULIN PADA PASIEN DM TIPE II DI RSU GMIM PANCARAN KASIH MANADO

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Mario Katuuk ◽  
Lenny Gannika
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Locus Of Control ◽  
Insulin Therapy ◽  
Health Locus Of Control ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Diabetes Melitus

Abstract: Diabetes Mellitus is one of the most common degenerative diseases and which cannot be cured, that can controlled through proper management. Insulin therapy as the most effective pharmacological therapy, requires compliance to reduce the risk of Diabetes Mellitus. Health locus of control is a set of beliefs about what is good and bad that affects person's health status, this is why the health locus of control related to compliance. Purpose to find out the correlation between health locus of control and compliance insulin therapy in type 2 Diabetes Mellitus patients at Pancaran Kasih GMIM Hospital Manado. Method uses cross sectional study design. Sample consisted of 40 respondents with purposive sampling method. Results with Kolmogorov Smirnov test at significance level of 95%, obtained ρ value is 0.077 greater than the significant value 0.05. Conclusion there is no correlation between health locus of control and compliance insulin therapy in type 2 Diabetes Mellitus patients at Pancaran Kasih GMIM Hospital Manado.Keywords: Diabetes mellitus, Health Locus Of Control, ComplianceAbstrak: Diabetes Melitus merupakan salah satu penyakit degeneratif yang paling sering diderita dan yang belum dapat disembuhkan, hal yang dapat dilakukan adalah dengan mengontrol penyakit lewat pengelolaan Diabetes Melitus yang tepat. Terapi insulin sebagai terapi farmakologi yang paling efektif, diperlukan perilaku patuh guna menurunkan resiko berkembangnya penyakit. Health locus of control sebagai seperangkat keyakinan mengenai apa yang baik dan yang buruk yang dapat mempengaruhi status kesehatan seseorang, hal ini mengapa health locus of control berkaitan dengan kepatuhan. Tujuan untuk mengetahui hubungan antara health locus of control dengan kepatuhan terapi insulin pada pasien Diabetes Melitus tipe 2 di RSU GMIM Pancaran Kasih Manado. Metode menggunakan desain penelitian cross sectional study. Sampel terdiri dari 40 responden dengan metode pengambilan sampel purposive sampling. Hasil dengan menggunakan uji kolmozorov smirnov pada tingkat kemaknaan 95%, didapatkan nilai ρ value 0,077 lebih besar dari nilai signifikan 0,05. Kesimpulan tidak terdapat hubunganantara health locus of control dengan kepatuhan terapi insulin pada pasien Diabetes Melitus tipe 2 di RSU GMIM Pancaran Kasih Manado.Kata Kunci: Diabetes Melitus, Health Locus Of Control, Kepatuhan

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