Vitamin D deficiency prevalence among healthy term infants at the age of 4–6 months: A cross-sectional observational study from tertiary care hospital setting

Introduction: Vitamin D deficiency is a common condition prevalent among both developed and developing countries where it is seen mostly in females. It has been linked to various skeletal and non-skeletal diseases. This study was done to find out the prevalence of Vitamin D deficiency and clinical features of deficient patients attending the outpatient department of a tertiary care hospital. Methods: This descriptive cross-sectional study was done among the patients attending the outpatient department of a tertiary care hospital in Kathmandu, Nepal. The study was conducted from May 2019 to July 2019. The ethical approval was taken from the Institutional Review Committee (ref no. 310520113). Convenient sampling was done. The collected data was entered in Microsoft Excel and was analyzed in the Statistical Package for the Social Sciences (SPSS) version 26. Results: Out of 481 participants, the prevalence of vitamin D deficiency was 335 (69.6%). Severe vitamin D deficiency was seen in 78 (16.2%) and insufficient vitamin D in 77 (16%) of the patients. The mean serum vitamin D concentration by gender was 22.38±17.07 ng/ml in males and 18.89±15.25 ng/ml in females. A total of 263 (54.6%) females and 72 (14.97%) males had vitamin D deficiency. The most common symptoms found in vitamin D deficiency patients were fatigue 187(55.8%), muscle cramps 131(39.1%), generalized myalgia 125(37.31%), bone and joint pain 111(33.13%) Conclusions: Vitamin D deficiency was prevalent especially in females and elderly people. Fatigability was present in more than half of the vitamin D deficient patients.

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A Comparative Study of Serum 25-Hydroxy Vitamin D Levels in Children with Seizures Receiving Monotherapy and Polytherapy

Journal of Child Science ◽

10.1055/s-0041-1740467 ◽

2021 ◽

Vol 11 (01) ◽

pp. e331-e337

Author(s):

Nazeem Fathima A. ◽

Radha Kumar ◽

Dev Kumar V. ◽

Devanand Gulab Chaudhary

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Tertiary Care ◽

Hospital Setting ◽

P Value ◽

Care Hospital ◽

Cross Sectional ◽

Increased Risk ◽

Vitamin D Levels ◽

25 Hydroxy Vitamin D

AbstractThe association between serum 25-hydroxy vitamin D (25(OH)D) antiepileptic drugs (AEDs) and bone health in individuals with epilepsy has been recognized for more than 30 years. Several studies indicate an increased risk for bone loss in patients on antiepileptic medication as well as low levels of serum 25(OH)D. Patients on polytherapy AED are at a higher risk of adverse drug effects compared with those on monotherapy. The present study assessed serum 25(OH)D levels in children receiving AED and compares those children receiving monotherapy versus polytherapy. This is a prospective cross-sectional study conducted in a tertiary care hospital setting on children with seizures receiving AEDs for period of more than 6 months. Participants were enrolled in three groups: 25 children on monotherapy, 25 children on polytherapy, and 25 healthy controls. Serum 25(OH)D level was performed for all children and analyzed. Serum 25(OH)D levels were normal in 52%, insufficient levels in 43.3%, and deficient in 6.7% of children. Vitamin D level was insufficient in 40% of children receiving monotherapy and 52% receiving polytherapy AED. Vitamin D deficiency was present in 4% in monotherapy group and 16% in polytherapy group which was statistically significant (p-value 0.047). Vitamin D deficiency was higher in children receiving AED compared with normal controls. Vitamin D deficiency and insufficiency were higher in children on polytherapy. Our study emphasized the importance of monitoring vitamin D levels in children receiving AED to detect abnormalities in vitamin D levels.

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Study of Vitamin-D Deficiency among Pregnant Women in their First Trimester Visiting a Tertiary Care Hospital: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association ◽

10.31729/jnma.6235 ◽

2021 ◽

Vol 59 (239) ◽

Author(s):

Dipty Shrestha ◽

Rachana Saha ◽

Chandrima Karki ◽

Shilpi Mahato

Keyword(s):

Vitamin D ◽

Pregnant Women ◽

Vitamin D Deficiency ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

First Trimester ◽

Cross Sectional Study ◽

Care Hospital ◽

Sectional Study ◽

Cross Sectional

Introduction: Vitamin-D deficient pregnant women are more likely to have pregnancy complications like pre-eclampsia, intrauterine growth restriction, diabetes, preterm birth, etc. Associated factors include ethnicity, skin coverall, use of sun protection, overweight, vitamin-D intake, and smoking. The objective of this study is to determine the prevalence of Vitamin-D deficiency among pregnant women in a tertiary level hospital. Methods: This study descriptive cross-sectional study was conducted at a tertiary care hospital from September 15th, 2020 to November 15th, 2020 where the pregnant women visiting for an antenatal checkup in the first trimester were enrolled. Ethical clearance was taken from the Institutional Review Committee of Kathmandu Medical College (reference no. 1808202003). A convenience sampling method was used. All the data were entered in the Statistical Package of the Social Sciences version 20.0 and analyzed. Point estimate at 90% Confidence Interval was calculated along with frequency and percentage for binary data. Results: Among a total of 47 cases, vitamin-D deficiency was seen in 21 (44.6%) (32.67-56.52 at 90% Confidence Interval). Conclusions: The prevalence of vitamin-D deficiency was similar to other studies done in similar settings.

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AB1292 PREVALENCE OF VITAMIN D DEFICIENCY AND ITS ASSOCIATED FACTORS AMONG RHEUMATOID ARTHRITIS PATIENTS MANAGED IN A RHEUMATOLOGY UNIT OF A TERTIARY CARE HOSPITAL IN SRI LANKA

10.1136/annrheumdis-2019-eular.3570 ◽

2019 ◽

Author(s):

sethuge silva ◽

Gunendrika Kasthuriratna ◽

Buddhika Mahesh ◽

Janalini Sashikaran

Keyword(s):

Rheumatoid Arthritis ◽

Vitamin D ◽

Sri Lanka ◽

Vitamin D Deficiency ◽

Associated Factors ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Rheumatology Unit

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A cross-sectional observational study of geriatric dermatoses in a Tertiary Care Hospital of Northern India

Indian Dermatology Online Journal ◽

10.4103/idoj.idoj_282_18 ◽

2019 ◽

Vol 10 (5) ◽

pp. 524 ◽

Cited By ~ 1

Author(s):

Reetu Agarwal ◽

Loknandani Sharma ◽

Ajay Chopra ◽

Debdeep Mitra ◽

Neerja Saraswat

Keyword(s):

Observational Study ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Cross Sectional ◽

Northern India

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Comparison of Vitamin D Levels between Genders, Age Groups and Geographical Locations in a Tertiary Care Hospital of Dakshina Kannada: A Cross Sectional Study

Scholars International Journal of Biochemistry ◽

10.36348/sijb.2020.v03i02.003 ◽

2020 ◽

Vol 03 (02) ◽

pp. 27-30

Author(s):

Mahalaxmi S Petimani ◽

Adarsh Aithal ◽

Prabhakar Adake

Keyword(s):

Vitamin D ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Age Groups ◽

Cross Sectional Study ◽

Care Hospital ◽

Sectional Study ◽

Cross Sectional ◽

Vitamin D Levels ◽

Geographical Locations

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An open model cross sectional observational study of hyponatremic patients in a tertiary care hospital

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20160506 ◽

2016 ◽

pp. 713-717

Author(s):

Harsha Gopinath ◽

T. Duraickannu ◽

Roopak Mohan ◽

G. Kumar

Keyword(s):

Observational Study ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Cross Sectional ◽

Open Model

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AN AN OBSERVATIONAL STUDY OF PRESCRIPTION PATTERN OF DRUGS FOR OSTEOARTHRITIS IN A NORTH INDIAN MEDICAL COLLEGE

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2019.v12i7.33882 ◽

2019 ◽

pp. 308-310

Author(s):

ASHWANI UMMAT ◽

RANJODH JEET SINGH ◽

SONIA KOCHHAR

Keyword(s):

Observational Study ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Oral Route ◽

Care Hospital ◽

Age Group ◽

Cross Sectional ◽

Prescription Pattern ◽

Medical College ◽

Indian Medical

Objective: The objective of the study is to analyze the prescription pattern of drugs for osteoarthritis (OA) in a north Indian medical college collaborated with a tertiary care hospital. Methods: An observational study was conducted on 300 patients diagnosed with OA in the department of orthopedics in collaboration with the department of pharmacology, and thus, prescription was collected as in a cross-sectional manner for 6 months and the same were analyzed in the Department of Orthopedics in tertiary care hospital collaborated with medical college. Results: The average age of patients participating in this present study was 56.46±7.4 years with affected age group of 46-60 years. 60 % of females were affected by osteoarthritis outnumbering male (40 %) patients in this present study. The most commonly involved joint was knee joint (87.33 %) in patients diagnosed with osteoarthritis followed by back (6.67 %) and hip joint (6%). The combination therapy (90 %) outweighed monotherapy (10 %) with preferred route of drug administration as oral route (90 %) followed by topical route (10 %). The average number of drugs prescribed for patients of osteoarthritis was 2.62±0.76. This present study concludes that NSAIDs (45.8%) were prescribed most commonly. However, the drug paracetamol was lesser prescribed and other drugs such as Diclofenac (27.22 %) and acetaminophen (34.44 %) most of all followed by Nimesulide (16.67 %), ibuprofen (13.33 %) and Rofecoxib/valdecoxib (8.33 %) were prescribed. Conclusion: This present study concludes that NSAIDs were most commonly prescribed as p-drugs while paracetamol was undermined prescribed.

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