Sopravvivere al cancro: una rassegna sulla Qualitŕ di Vita nella cancer survivorship

2009 ◽  
pp. 55-71
Author(s):  
Maria Antonietta Anunziata ◽  
Barbara Muzzatti ◽  
Katia Bianchet ◽  
Massimiliano Berretta ◽  
Emanuela Chimienti ◽  
...  

- Thanks to substantial medical progress, today the number of cancer survivors constantly increases. Thus, ever more frequently, patients and healthy professionals must treat a new condition: the cancer survivorship. This condition is peculiar for both its somatic (e.g. the late and long term effects of the treatments) and psychosocial (e.g. psychological distress, fear for a relapse, perceived social support) implications. The present paper is a review of the recent international literature about cancer survivorship; a condition still less known in Italy. First the definition of cancer survivorship is discussed and then cancer survivorship is addressed through a four point model of the concept of Quality of Life. In the last section, the authors will examine the expectation for future research, as well as the possible limitations, together with the practical implications of this topic.

2013 ◽  
Vol 13 (3) ◽  
pp. 365-370
Author(s):  
D. Whitaker ◽  
D. Green

AbstractPurposeKey advances in cancer treatment have led to an increasing number of long-term cancer survivors. Knowledge of the long-term effects of cancer treatment on leukaemia survivors is to some degree limited. This article investigates the effects of the treatment of childhood leukaemia on the quality of life (QOL), the physical and the psychological wellbeing and general development of survivors. This article reviews current literature to examine existing gaps in knowledge and identify a potential focus of future research and clinical practice.Materials and methodsOnline systematic searching, along with historical searching took place in order to retrieve relevant primary research papers for the review. Strict inclusion and exclusion criteria were applied to the literature, to create a manageable amount of research papers.ResultsThe extent of intellectual impairment among radiotherapy patients was significantly greater than those treated with chemotherapy only. Body composition, including endocrine function, is readily affected by cancer treatment. Early identification and interventions can greatly improve the QOL of survivors.ConclusionFurther research into the effect of treatment modality on the extent of chronic effects, along with investigations into the needs of the whole family unit, is required. Future practice must take into account long-term implications while ensuring effective holistic care.


2019 ◽  
Vol 17 (12) ◽  
pp. 1557-1568 ◽  
Author(s):  
Chunkit Fung ◽  
Paul C. Dinh ◽  
Sophie D. Fossa ◽  
Lois B. Travis

Testicular cancer (TC) is the most common cancer among men aged 18 to 39 years. It is highly curable, with a 10-year relative survival approaching 95% due to effective cisplatin-based chemotherapy. Given the increasing incidence of TC and improved survival, TC survivors (TCS) now account for approximately 4% of all US male cancer survivors. They have also become a valuable cohort for adult-onset cancer survivorship research, given their prolonged survival. Commensurately, long-term treatment-related complications have emerged as important survivorship issues. These late effects include life-threatening conditions, such as second malignant neoplasms and cardiovascular disease. Moreover, TCS can also experience hearing loss, tinnitus, neurotoxicity, nephrotoxicity, pulmonary toxicity, hypogonadism, infertility, anxiety, depression, cognitive impairment, and chronic cancer-related fatigue. Characterization of the number and severity of long-term adverse health outcomes among TCS remains critical to develop risk-stratified, evidence-based follow-up guidelines and to inform the development of preventive measures and interventions. In addition, an improved understanding of the long-term effects of TC treatment on mortality due to noncancer causes and second malignant neoplasms remains paramount. Future research should focus on the continued development of large, well-characterized clinical cohorts of TCS for lifelong follow-up. These systematic, comprehensive approaches can provide the needed infrastructure for further investigation of long-term latency patterns of various medical and psychosocial morbidities and for more in-depth studies investigating associated etiopathogenetic pathways. Studies examining premature physiologic aging may also serve as new frontiers in TC survivorship research.


2005 ◽  
Vol 85 (2) ◽  
pp. 297-307 ◽  
Author(s):  
Sukhdev S. Malhi ◽  
Jeff J. Schoenau ◽  
Cynthia A. Grant

In the Parkland region of the Canadian prairies, Canola (Brassica napus L. or Brassica rapa L.) is an important cash crop. Canola has a high requirement for sulphur (S). However, many soils in this region are deficient or potentially deficient in plant-available S for optimum canola seed yield. Application of sulphate-S at about 15–30 kg S ha-1 is usually sufficient to prevent S deficiency in canola on most of the S-deficient soils. Application of sulphate-S to canola at seeding time gives the highest increase in yield and S uptake. Deficiencies of S in canola plants can be prevented and/or corrected and seed yield improved with the use of sulphate-S fertilizers in the growing season. Application of sulphate-S at bolting can substantially restore seed yield, while an application at early flowering can moderately correct S deficiency damage. Side-banding is the most effective way to apply sulphate-S fertilizers to produce maximum seed yield and to prevent any damage to canola seedlings from seed-row placement. In relatively moist areas, broadcast-incorporation methods can produce seed yield similar to side-banding in most years. Elemental S fertilizers were not effective in increasing seed yield in the year of application, and were generally less effective than sulphate-S fertilizer even after multiyear annual applications, especially when applied in spring. Autumn-applied elemental S was more effective than spring-applied elemental S. Banding delayed availability of elemental S as compared to broadcast application. Use of granular elemental S products is not reliable for optimum seed yield of canola under Canadian prairie conditions on S-deficient soils, particularly in the initial year and with spring application or band placement. Elemental S fertilizers may have a role to maintain or build-up sulphate-S levels in soils marginally low in S where residual benefits are desirable, but management decisions should consider both immediate and long-term effects of S fertilizer on seed yield, seed quality and economics. The findings suggest the need of future research to increase dispersion and distribution of S particles from granules for faster oxidation of elemental S in soil, and to develop elemental S fertilizer products/formulations that can be used on a commercial scale to prevent and/or correct S deficiency in the growing season to optimize seed yield and quality of canola. Research is also required to determine the long-term effects of balanced application of S with other nutrients on soil quality, accumulation and distribution of nitrate-N, sulphate-S and other nutrients in the soil profile, efficiency of nutrient, water and energy use, and crop diseases. More research should be conducted in relation to soil/plant tissue testing issues for optimum seed yield and quality of canola. Key words: Balanced fertilization, canola, elemental S fertilizers, method of application, rate of S, seed quality, seed yield, sulphate-S fertilizers


Author(s):  
Juliana Alves Sousa Caixeta ◽  
Jessica Caixeta Silva Sampaio ◽  
Vanessa Vaz Costa ◽  
Isadora Milhomem Bruno da Silveira ◽  
Carolina Ribeiro Fernandes de Oliveira ◽  
...  

Abstract Introduction Adenotonsillectomy is the first-line treatment for obstructive sleep apnea secondary to adenotonsillar hypertrophy in children. The physical benefits of this surgery are well known as well as its impact on the quality of life (QoL), mainly according to short-term evaluations. However, the long-term effects of this surgery are still unclear. Objective To evaluate the long-term impact of adenotonsillectomy on the QoL of children with sleep-disordered breathing (SDB). Method This was a prospective non-controlled study. Children between 3 and 13 years of age with symptoms of SDB for whom adenotonsillectomy had been indicated were included. Children with comorbities were excluded. Quality of life was evaluated using the obstructive sleep apnea questionnaire (OSA-18), which was completed prior to, 10 days, 6 months, 12 months and, at least, 18 months after the procedure. For statistical analysis, p-values lower than 0.05 were defined as statistically significant. Results A total of 31 patients were enrolled in the study. The average age was 5.2 years, and 16 patients were male. The OSA-18 scores improved after the procedure in all domains, and this result was maintained until the last evaluation, done 22 ± 3 months after the procedure. Improvement in each domain was not superior to achieved in other domains. No correlation was found between tonsil or adenoid size and OSA-18 scores. Conclusion This is the largest prospective study that evaluated the long-term effects of the surgery on the QoL of children with SDB using the OSA-18. Our results show adenotonsillectomy has a positive impact in children's QoL.


Author(s):  
Teresa Zetzl ◽  
Andre Pittig ◽  
Agnes Renner ◽  
Birgitt van Oorschot ◽  
Elisabeth Jentschke

Abstract Objective To examine the efficacy of reminder e-mails to continue yoga therapy on practice frequency and fatigue in cancer patients and long-term effects of yoga on fatigue, depression, and quality of life. Methodology One hundred two cancer patients who completed an 8-week yoga therapy were randomly allocated to two groups: reminder (N = 51) vs. no-reminder group (N = 51). After completing yoga therapy, the reminder group received weekly e-mails for 24 weeks, which reminded them of practicing yoga, whereas the no-reminder group did not. Primary outcomes were fatigue and practice frequency, and long-term outcomes were fatigue, depression, and quality of life. Data were assessed using questionnaires after yoga therapy (T1) and 6 months after completing yoga therapy (T2). Result A significantly stronger reduction of general (p = 0.038, d = 0.42) and emotional fatigue (p = 0.004, d = 0.59) and a higher increase of practice frequency (p = 0.015, d = 0.52) between T1 and T2 were found for the reminder group compared to the no-reminder group. In the mediation model, practice frequency as a mediator partially explained the changes in emotional fatigue (indirect effect B =  − 0.10). Long-term effects of yoga therapy regarding fatigue, depression, and quality of life were found (F > 7.46, p < 0.001, d > 0.54). Conclusion Weekly reminder e-mails after yoga therapy can positively affect general and emotional fatigue and help cancer patients with fatigue establish a regular yoga practice at home. However, higher practice frequency did not lead to higher physical or cognitive fatigue improvement, suggesting other factors that mediate efficacy on physical or cognitive fatigue, such as mindfulness or side effects of therapy.


2021 ◽  
pp. 003232172110072
Author(s):  
Ramon van der Does ◽  
Vincent Jacquet

Deliberative minipublics are popular tools to address the current crisis in democracy. However, it remains ambiguous to what degree these small-scale forums matter for mass democracy. In this study, we ask the question to what extent minipublics have “spillover effects” on lay citizens—that is, long-term effects on participating citizens and effects on non-participating citizens. We answer this question by means of a systematic review of the empirical research on minipublics’ spillover effects published before 2019. We identify 60 eligible studies published between 1999 and 2018 and provide a synthesis of the empirical results. We show that the evidence for most spillover effects remains tentative because the relevant body of empirical evidence is still small. Based on the review, we discuss the implications for democratic theory and outline several trajectories for future research.


2013 ◽  
Vol 190 (1) ◽  
pp. 187-193 ◽  
Author(s):  
Chyng-Wen Fwu ◽  
Paul W. Eggers ◽  
Steven A. Kaplan ◽  
Ziya Kirkali ◽  
Jeannette Y. Lee ◽  
...  

2017 ◽  
Vol 23 (3) ◽  
pp. 721-734 ◽  
Author(s):  
Matthias Murawski ◽  
Markus Bick

Purpose Considering working in the digital age, questions on the consequences for the individual workers are, so far, often neglected. The purpose of this paper is to deal with the question of whether the digital competences of the workforce is a research topic. The authors argue for the thesis that it is indeed a research topic. Design/methodology/approach In addition to a literature analysis of the top IS, HR, and learning publications, non-scientific sources, as well as the opinions of the authors, are included. The authors’ thesis is challenged through a debate of corresponding pros and cons. Findings The definition of digital competences lacks scientific depth. Focussing on the workforce is valid, as a “lifelong” perspective is not mandatory for research. Digital competence research is a multidisciplinary task to which the IS field can make a valuable contribution. Research limitations/implications Although relevant references are included, some aspects are mainly driven by the opinions of the authors. The theoretical implications encompass a call for a scientific definition of digital competences. Furthermore, scholars should focus on the competences of the workforce, including occupations, roles, or industries. The authors conclude by providing a first proposal of a research agenda. Practical implications The practical implications include the alignment of multiple stakeholders for the design of “digital” curricula and the integration by HR departments of the construct of digital competences, e.g. for compensation matters and job requirements. Originality/value This paper is one of very few contributions in the area of the digital competences of the workforce, and it presents a starting point for future research activities.


2006 ◽  
Vol 21 (6) ◽  
pp. 746-753 ◽  
Author(s):  
Andrew Siderowf ◽  
Jurg L. Jaggi ◽  
Sharon X. Xie ◽  
Catherine Loveland-Jones ◽  
Lewis Leng ◽  
...  

2017 ◽  
Vol 7 (2) ◽  
pp. 136
Author(s):  
Mussie T. Tessema ◽  
Kubilay Gok ◽  
Alex Ngoma ◽  
Mengsteab Tesfayohannes ◽  
Gerry V. Fernando

This paper uses Singapore as a case study to illustrate how staffing policies and practices affect the quality of the workforce which ultimately influence performance at employee and organization level. It reveals that Singapore public service has been able to put in place most of the ‘critical factors’ for an effective staffing system management. The presence of those critical factors have played an important role in making Singapore to be one of the most effective public services in the world. Finally, it forwards theoretical and practical implications of the study and future research direction.


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