scholarly journals Synthesis and bioactivity of benzohydrazide derivatives

2020 ◽  
Vol 10 (4) ◽  
pp. 5797-5802
Keyword(s):  
Insecticidal Activity ◽  
Biological Activities ◽  
House Fly ◽  
Rice Weevil ◽  
Gall Formation ◽  
One Stage ◽  
One Step ◽  
Cucumber Roots ◽  
Activity Decrease

N'-[4-(Hydroxyimino)-cyclohexa-2,5-dien-1-ylidene]-benzohydrazides have been synthesized by reaction of 4-(hydroxyimino)-cyclohexa-2,5-dien-1-one with different benzohydrazides in one stage. N'-(4-[(Aroyloxy)imino]cyclohexa-2,5-dien-1-ylidene)-benzohydrazides were obtained in reaction of 4-[(aroyloxy)imino]cyclohexa-2,5-dien-1-ones with corresponding benzohydrazides in one step too. Biological activities of the synthesized compounds were studied. N'-[4-{[(4-nitrobenzoyl)oxy]imino}cyclohexa-2,5-dien-1-ylidene]benzo-hydrazide showed high insecticidal activity against house fly and rice weevil. 3,4-Dichloro-N'-[4-(hydroxyimino)cyclohexa-2,5-dien-1-ylidene]benzohydrazide and N'-{4-[(benzoyloxy)imino]-cyclohexa-2,5-dien-1-ylidene}-2-bromobenzohydrazide showed excellent anti-nematode activity: decrease in gall formation on the cucumber roots was 93 and 91%, respectively.

scholarly journals One-step synthesis, characterization and properties of novel hybrid electromagnetic nanomaterials based on polydiphenylamine and Co–Fe particles in the absence and presence of single-walled carbon nanotubes

RSC Advances ◽  
2021 ◽  
Vol 11 (40) ◽  
pp. 24772-24786
Author(s):  
Sveta Zhiraslanovna Ozkan ◽  
Galina Petrovna Karpacheva ◽  
Mikhail Nikolaevich Efimov ◽  
Andrey Aleksandrovich Vasilev ◽  
Dmitriy Gennad'evich Muratov ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Single Walled Carbon Nanotubes ◽  
Hybrid Nanomaterials ◽  
Single Walled Carbon ◽  
One Stage ◽  
Ir Heating ◽  
One Step ◽  
Walled Carbon Nanotubes ◽  
Self Organizing

In a self-organizing system within one stage under IR heating conditions, hybrid nanomaterials are formed with a structure that contains bimetallic Co–Fe particles, free or immobilized on the SWCNT surface, dispersed in the polymer PDPA matrix.

One step hydrothermal green approach of CuO/Ag nanocomposites: analysis of structural, biological activities

2019 ◽  
Vol 6 (9) ◽  
pp. 095036 ◽  
Author(s):  
E Nandhakumar ◽  
P Priya ◽  
P Selvakumar ◽  
E Vaishnavi ◽  
A Sasikumar ◽  
...  
Keyword(s):  
Biological Activities ◽  
Green Approach ◽  
One Step

scholarly journals Insecticidal activity of citronella grass essential oil on Frankliniella schultzei and Myzus persicae

2013 ◽  
Vol 37 (2) ◽  
pp. 138-144 ◽  
Author(s):  
Patrícia Fontes Pinheiro ◽  
Vagner Tebaldi de Queiroz ◽  
Vando Miossi Rondelli ◽  
Adilson Vidal Costa ◽  
Tiago de Paula Marcelino ◽  
...  
Keyword(s):  
Essential Oil ◽  
Insecticidal Activity ◽  
Myzus Persicae ◽  
Green Peach Aphid ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Economic Losses ◽  
Frankliniella Schultzei ◽  
Wide Range ◽  
Citronella Grass

The thrips, Frankliniella schultzei, and green peach aphid, Myzus persicae, cause direct damage to plants of economic importance and transmit phytoviruses, causing large economic losses. Chemical constituents of essential oils present a wide range of biological activities. The aim of this work was to evaluate insecticidal activity of essential oil from citronella grass, Cymbopogon winterianus, on F. schultzei and M. persicae. This essential oil was obtained by steam distillation and components were identified by GC/FID and GC/MS. A Potter spray tower was used to spray insects with the essential oil. The major constituents are geraniol (28.62%), citronellal (23.62%) and citronellol (17.10%). Essential oil of C. winterianus at 1% (w v-1) causes mortality in F. schultzei and M. persicae at 34.3% and 96.9%, respectively. The LC50 value for M. persicae was 0.36% and LC90 0.66%. Thus, citronella grass essential oil at 1% (w v-1) is more toxic to M. persicae than F. schultzei. This essential oil shows promise for developing pesticides to manage M. persicae.

Synthesis of biologically active heterocyclic compounds from allenic and acetylenic nitriles and related compounds

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Marthe Carine Djuidje Fotsing ◽  
Dieudonné Njamen ◽  
Zacharias Tanee Fomum ◽  
Derek Tantoh Ndinteh
Keyword(s):  
Michael Addition ◽  
Heterocyclic Compounds ◽  
Biological Activities ◽  
Biologically Active ◽  
Polycyclic Compounds ◽  
One Step ◽  
Pharmaceutical Properties ◽  
Related Compounds ◽  
Acetylenic Acids ◽  
The Michael Addition

Abstract Cyclic and polycyclic compounds containing moieties such as imidazole, pyrazole, isoxazole, thiazoline, oxazine, indole, benzothiazole and benzoxazole benzimidazole are prized molecules because of the various pharmaceutical properties that they display. This led Prof. Landor and co-workers to engage in the synthesis of several of them such as alkylimidazolenes, oxazolines, thiazolines, pyrimidopyrimidines, pyridylpyrazoles, benzoxazines, quinolines, pyrimidobenzimidazoles and pyrimidobenzothiazolones. This review covers the synthesis of biologically active heterocyclic compounds by the Michael addition and the double Michael addition of various amines and diamines on allenic nitriles, acetylenic nitriles, hydroxyacetylenic nitriles, acetylenic acids and acetylenic aldehydes. The heterocycles were obtained in one step reaction and in most cases, did not give side products. A brief discussion on the biological activities of some heterocycles is also provided.

scholarly journals Cytotoxicity against HL60 Cells of Ficifolidione Derivatives with Methyl, n-Pentyl, and n-Heptyl Groups

Molecules ◽  
2019 ◽  
Vol 24 (22) ◽  
pp. 4081
Author(s):  
Hisashi Nishiwaki ◽  
Megumi Ikari ◽  
Satomi Fujiwara ◽  
Kosuke Nishi ◽  
Takuya Sugahara ◽  
...  
Keyword(s):  
Insecticidal Activity ◽  
Alkyl Group ◽  
Caspase 3 ◽  
Biological Activities ◽  
Mosquito Larvae ◽  
Leukaemia Cell ◽  
Leukaemia Cell Line ◽  
Hl60 Cells ◽  
Flow Cytometric ◽  
Alkyl Groups

Ficifolidione, a natural insecticidal compound isolated from the essential oils of Myetaceae species, is a spiro phloroglucinol with an isobutyl group at the C-4 position. We found that ficifolidione showed cytotoxicity against cancer cells via apoptosis. Replacement of the isobutyl group by n-propyl group did not influence the potency, but the effect of the replacement of this group by a shorter or longer alkyl group on the biological activity remains unknown. In this study, ficifolidione derivatives with alkyl groups such as methyl, n-pentyl, and n-heptyl group—instead of the isobutyl group at the C-4 position—were synthesized to evaluate their cytotoxicity against the human promyelocytic leukaemia cell line HL60 and their insecticidal activity against mosquito larvae. The biological activities of their corresponding 4-epimers were also evaluated. As a result, the conversion of the isobutyl group to another alkyl group did not significantly influence the cytotoxicity or insecticidal activity. In HL60 cells treated with the n-heptyl-ficifolidione derivative, the activation of caspase 3/7 and the early stages of apoptosis were detected by using immunofluorescence and flow cytometric techniques, respectively, suggesting that the cytotoxicity should be induced by apoptosis even though the alkyl group was changed.

Insecticidal activity of essential oils from native medicinal plants of Central Argentina against the house fly, Musca domestica (L.)

2009 ◽  
Vol 106 (1) ◽  
pp. 207-212 ◽  
Author(s):  
Sara M. Palacios ◽  
Alberto Bertoni ◽  
Yanina Rossi ◽  
Rocío Santander ◽  
Alejandro Urzúa
Keyword(s):  
Medicinal Plants ◽  
Essential Oils ◽  
Musca Domestica ◽  
Insecticidal Activity ◽  
House Fly ◽  
Central Argentina

scholarly journals Antioxidant, Antifungal and Aphicidal Activity of Triterpenoids Spinasterol, 22,23-Dihydrospinasterol From Colocynthis (Citrullus Colocynthis L.) Leaves

2021 ◽  
Author(s):  
Maqsood Ahmed ◽  
Allah Rakha Sajid ◽  
Taswar Ahsan ◽  
Dilbar Hussain ◽  
Abdul Mateen ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Insecticidal Activity ◽  
Magnaporthe Grisea ◽  
Fungicidal Activity ◽  
Biological Activities ◽  
Strong Positive Correlation ◽  
Citrullus Colocynthis ◽  
Mycelium Growth ◽  
Growth Inhibition Assay ◽  
Aphicidal Activity

Abstract Terpenoids from natural plants resources are valuable for diverse biological activities which exhibited important part in medical and agrochemicals industry. This study aimed to assess the antioxidant, antifungal and aphicidal activity of a mixture of Spinasterol, 22,23-dihydrospinasterol from Citrullus colocynthis leaves. 1, 1-diphenyl-2-picrylhydrazyl (DPPH) was used to assess the antioxidant activity whereas, antifungal activity was tested by mycelium growth inhibition assay on three pathogenic fungi Magnaporthe grisea, Rhizoctonia solani and Phytophthora infestans. Aphicidal activity against adults of Myzus persicae was also determined via In-vitro and In-vivo assays. The outcome of the study exposed that Spinasterol, 22, 23-dihydrospinasterol afforded moderate antioxidant activity even at lower concentrations i.e. 19.98, 31.52, 36.61 and 49.76% at 0.78, 3.0, 12.5 and 50µgmL− 1 respectively. However, reasonable fungicidal activity of Spinasterol, 22; 23-dihydrospinasterol was recorded as being EC50 values 129.5 and 206.1µgmL− 1 against R. solani and M. grisea respectively. On the other hand, Boscalid and Carbendazim being a positive control proved highly effective against all fungi except for M. grisea and P. infestans with EC50 values 868 and 272109µgmL− 1 respectively. The significant insecticidal activity was afforded via residual as well as greenhouse assay being LC50 values as 42.46, 54.86, 180.9 µgmL− 1 and 32.71, 42.46 and 173.8µgmL− 1 at 72, 48 and 24 h respectively. Moreover, antioxidant activity of Spinasterol, 22,23-dihydrospinasterol presented strong positive correlation versus antifungal and insecticidal activity. Spinasterol, 22,23-dihydrospinasterol possess good antioxidant and aphicidal activity with moderate fungicidal activity which could be a suitable candidate as an alternative to synthetic pesticidal agents.

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