Study on Risk Factors and Pattern of Coronary Artery Involvement in Young Acute Coronary Syndrome Patients

2017 ◽  
Vol 32 (1) ◽  
pp. 40-44
Author(s):  
Tanveer Ahmad ◽  
Muhammad Badrul Alam ◽  
Amiruzzaman Khan ◽  
AKM Monwarul Islam ◽  
Zakir Hossain ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Positive Family History ◽  
Young Patients ◽  
Younger Patients ◽  
Coronary Syndrome ◽  
Vessel Disease ◽  
Coronary Artery Involvement ◽  
Triple Vessel Disease

Aims: To compare the risk factors and pattern of coronary artery involvement in young acute coronary syndrome patients with that of the elderly.Methods: This was a cross sectional analytic study done in the Department of Cardiology, Sir Salimullah Medical College and Mitford Hospital during November 2015 to October 2016.Results: Study population was divided into two subgroups, those 18-40 years were considered as young and those >40 years were considered as elderly. Young patients had greater prevalence of smoking, dyslipidemia and positive family history of Ischemic Heart Disease (IHD), whereas hypertension was more prevalent in the elderly. Younger patients mainly presented with STEMI and predominantly had single vessel disease (SVD), whereas elderly patients frequently presented with NSTEMI and Unstable angina and had higher incidence of double vessel disease (DVD) and triple vessel disease (TVD).Conclusion: Younger patients had a different pattern of risk factors and coronary artery involvement in comparision to the elderly.Bangladesh Heart Journal 2017; 32(1) : 40-44

Abstract 12850: Complex Lesion Characteristics Would be the Potential Risk Factors for Ventricular Fibrillation With Acute Coronary Syndrome

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Youichirou Sugizaki ◽  
Makoto Takemoto ◽  
Hiromi Toki ◽  
Yu Taniguchi ◽  
Nobuaki Igarashi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Ventricular Fibrillation ◽  
Potential Risk ◽  
Multiple Logistic Regression Analysis ◽  
Influential Factors ◽  
Coronary Syndrome ◽  
Vessel Disease ◽  
Potential Risk Factors

Background: In the setting of acute coronary syndrome (ACS), ventricular fibrillation (VF) was serious and fatal complication. However, even though ischemia was well known as the risk for occurrence of VF, what influential factors of ACS patients related to VF were still unclear. We performed extracorporeal cardiopulmonary resuscitation for VF with ACS patients taken to our institute and performed coronary angiography to make definite diagnosis. Accordingly, We sought to the risk factors for VF with ACS. Methods: Consecutive 246 ACS patients hospitalized and underwent emergent coronary revascularization from September 2010 to September 2014 were enrolled. In these, patients with VF were categorized into VF group, and patients without VF were into non-VF group. We reviewed patients’ characteristics, including medications, past histories and laboratory findings, and CAG findings (lesion characteristics with ACC/AHA classification, number of disease vessels, existence of chronic total occlusion (CTO) and left-main coronary artery (LMCA) lesion) retrospectively. Results: Fifty-seven patients developed ACS with VF (VF group), and 189 patients were without VF (non-VF group). Comparing between the groups, the morbidity of previous angina pectoris or coronary artery bypass grafting were significantly higher in VF groups (32.1%-16.0%, p=0.01, 14.3%-1.1%, p<0.001, respectively). The prevalence of Complex lesion characteristics, such as multi vessel disease, CTO and LMCA lesion, was also higher in VF group (71.9%-42.8%, 43.9%-13.9%, 15.8%-6.3%, all p < 0.025, retrospectively). Moreover, multiple logistic regression analysis revealed multi vessel disease and existence of CTO lesion were independent factors for VF. Conclusion: VF group had more complex characteristics of coronary artery disease. Complex lesion characteristics, such as multi vessel disease, CTO and LMCA lesion, would be potential risk factors of VF with ACS patients.

scholarly journals Clinical Characteristics and Angiographic Profile of Acute Coronary Syndrome Patients in a Tertiary Hospital of Bangladesh

2018 ◽  
Vol 33 (1) ◽  
pp. 10-15
Author(s):  
Mohsin Ahmed ◽  
Khandaker Abu Rubaiyat ◽  
Mohammed Abaye Deen Saleh ◽  
Abdul Wadud Chowdhury ◽  
CM Khudrate E Khuda ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Healthy Person ◽  
Diabetic Patients ◽  
College Hospital ◽  
Coronary Syndrome ◽  
Triple Vessel Disease ◽  
Artery Disease

Aims: Coronary artery disease is a devastating disease precisely because an otherwise healthy person in the prime of life may die or become disabled without warning. The objectives were to study the clinical profile, risk factors prevalence, angiographic distribution and severity of coronary artery stenosis in acute coronary syndrome (ACS) patients admitted in Cardiology Department of Dhaka Medical College Hospital, Dhaka.Materials and Methods: A total of 800 patients of ACS were analyzed for various risk factors, angiographic patterns and severity of coronary artery disease at DMCH, Dhaka, Bangladesh.Results: Mean age of presentation was 51.27±8.80 years. Majority were male 628 (78.5%) and rest were females (21.5%). Most patients had ST elevated myocardial infarction (STEMI) 509 (63.6%) followed by non-STEMI (NSTEMI) 207 (25.9%) and Unstable Angina (UA) 84 (10.5%). Risk factors: smoking was present in 388 (48.5%), hypertension in 289 (36.13%), diabetes in 235 (29.38%), dyslipidaemia in 169 (21.13%) and obesity in 356 (44.5%) patients. Singlevessel disease was present in 30.32% patients, Doublevessel disease was present in 23.23% patients and Triple vessel disease was present in 27.15% patients.Conclusion: STEMI was the most common presentation. ACS occurred earlier in comparison to Western population. Smoking was most prevalent risk factor. Diabetic patients had more multivessel disease.Bangladesh Heart Journal 2018; 33(1) : 10-15

scholarly journals Acute coronary syndrome in young patients: clinical features and risk factors

2018 ◽  
Vol 17 (6) ◽  
pp. 13-19
Author(s):  
I. V. Ponomarenko ◽  
I. A. Sukmanova ◽  
V. A. Elykomov
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Clinical Features ◽  
Comparison Group ◽  
Young Patients ◽  
High Density Lipoproteins ◽  
Coronary Syndrome ◽  
Q Wave

Aim. To study the clinical features and risk factors (RF) associated with the development of acute coronary syndrome (ACS) in young patients.Material and methods. The study included 474 patients with ACS. Depending on age, patients were divided into 2 groups. The first group consisted of 299 patients of young age (25-44 years), the comparison group consisted of 175 patients of mean and old age (45-74 years). Clinical and anamnestic data, parameters of general clinical and biochemical tests, electrocardiography, echocardiography and coronary angiography were determined in all patients, and polymorphisms in FII G20210-A, FV G1691-A, MTHFR C677-T genes were determined in 116 patients. The control group consisted of 53 healthy volunteers.Results. ACS in patients <45 years old is most common in men. The number of women with ACS increases as elder patient is. The incidence of myocardial infarction (MI) and unstable angina, ST-elevated MI and non ST-segment elevation MI, Q-wave and non-Q-wave MI had no differences between patients of the younger and older age groups. In younger patients, anterior localization of myocardial infarction was more common, in mean and old patients — posterior. Complications of MI in young patients were less common than in the comparison group. In patients of mean and old ages, acute coronary event was preceded by a clinic of angina, in young patients most often it was the debut of coronary artery disease. It was revealed that single-vessel coronary lesion is more characteristic for young patients, for the elderly patients — two-vessel and multi-vessel. Pathology of the anterior descending coronary artery prevailed in both groups of patients. Most patients in both groups underwent myocardial revascularization. MI as a result of coronary artery thrombosis happened more often in young patients. The most significant RF associated with the ACS development were: increased total cholesterol and low density lipoproteins, decreased high density lipoproteins, increased body mass index, smoking, polymorphism of MTHFR-homozygote, hereditary tainted with smoking, aggravation in combination with F5-homozygote, hereditary tainted in combination with MTHFR-homozygote, hereditary tainted in combination with smoking and MTHFR homozygote.Conclusion. We identified clinical features and RF, mostly associated with the development of ACS in patients <45 years of age. The results can serve as additional indicators showed the risk of ACS development.

scholarly journals Distribution of Risk Factors in Patients with Acute Coronary Syndrome – a Hospital Based Study

2003 ◽  
Vol 42 (148) ◽  
Author(s):  
Man B KC ◽  
S Rajbhandari ◽  
D Sharma ◽  
R Malla ◽  
YR Limbu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Disease Risk ◽  
Positive Family History ◽  
Modifiable Risk Factors ◽  
Coronary Syndrome ◽  
Strong Trend ◽  
Artery Disease

A total of 230 patients admitted in coronary care unit of Shahid Gangalal National Heart Centre in betweenNovember 2001 and October 2002 were studied. 157 (68.2%) were male, with mean age of 62.8±11.8 years.Majority of acute coronary syndrome (ACS) events were observed in males with advanced age (> 65 years).About 68% patients with ACS were smoker, the most common modifiable risk factor followed by hypertension,dyslipidaemia and diabetes. A strong trend towards development of coronary artery disease (CAD) wasfound in subjects with positive family history of CAD. Multiple risk factors (2 or more) were present in vastmajority of patients. Modifiable risk factors, with smoking at number one position are more common inacute coronary syndrome patients. Appropriate management of modifiable risk factors is advisable to reducethe incidence of coronary artery disease.Key Words: Coronary Artery Disease, Risk Factors.

scholarly journals A Study on Angiographic profile of Acute Coronary Syndrome in Smokers

2020 ◽  
Vol 3 (1) ◽  
pp. 32-41
Author(s):  
Hemasundar Korrapati ◽  
B.V. Narayana Reddy ◽  
Supraja Chegireddy
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Killip Class ◽  
Medical College ◽  
Coronary Syndrome ◽  
Vessel Disease ◽  
Artery Disease ◽  
Type 3

Background: Coronary artery disease is a devastating disease precisely because an otherwise healthy person in the prime of life may die or become disabled without warning. The objectives were to study the clinical profile, risk factors prevalence, angiographic distribution and severity of coronary artery stenosis in acute coronary syndrome (ACS) patients admitted in Cardiology Department of Cardiology Katuri Medical College & Hospital, Guntur.Subjects and Methods:A total of 208 patients of ACS were analyzed for various risk factors, angiographic patterns and severity of coronary artery disease in smokers vs non-smokers at Katuri Medical College, Andhra Pradesh.Results:Study group consisted of 208 subjects, of which 108(51.9%) subjects were smokers including all forms of tobacco use and 100(48.1 Out of 108 study subjects in  the  smokers group, family history of CAD  was present in 21(19.4%) subjects. Killip class is not applicable to 13 (12%) study groups as they presented with Unstable Angina with ECG changes. Killip class 1 was most common presentation (67.6%) in smokers. 28 patients (25.9%) had LV dysfunction with EF < 50% by echocardiography. 80 patients (74.1%) had normal LV function. The mean EF was 55.56+/-10.16%. The median EF was 56.5%. LAD was type 3 in 100 (92.6%) patients and type 4 in 8 (7.4%) patients   out of 108 study subjects.LAD type 3 was statistically significant with P value < 0.05 when compared with LAD type 4. No statistically significant difference was seen with respect to the Normal coronary arteries as CAG diagnosis between smokers and non-smokers(6.7% versus 8%,p>0.1,Not significant).Conclusion: Smokers were predominantly male and around 3 years younger than non-smokers. Diabetes mellitus and hypertension were less common among smokers and single-vessel disease was the more common angiographic finding for smokers as compared to 3-vessel disease for non-smokers. ST-segment elevation myocardial infarction in smokers despite younger age and the low atherosclerotic risk profile, in our region, emphasize the need for nicotine addiction management and smoking cessation campaigns at large and for pre-discharge counseling.

scholarly journals Clinical characteristics, risk factors and angiographic profile of acute coronary syndrome patients in a tertiary care center of Nepal.

2019 ◽  
Vol 16 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Abhishesh Shakya ◽  
Sunil Chandra Jha ◽  
Ratna Mani Gajurel ◽  
Chandra Mani Poudel ◽  
Ravi Sahi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
St Elevation Myocardial Infarction ◽  
Coronary Syndrome ◽  
Vessel Disease ◽  
St Elevation ◽  
Artery Disease

Background and Aims: Acute coronary syndrome (ACS) refers to a group of clinical symptoms consistent with new onset or worsening ischemic symptoms. ST-elevation myocardial infarction (STEMI), non-ST elevation myocardial infarction (NSTEMI) and unstable angina (UA) are the three types of ACS. The objectives were to study the risk factors prevalence, angiographic distribution and severity of coronary artery stenosis in ACS among patients admitted in Cardiology Department of Manmohan Cardiothoracic Vascular and Transplant Center (MCVTC). Methods: This is a restrospective study of 419 ACS patients admitted and treated in MCVTC from November 2017 to October 2018. Patients were divided into STEMI, NSTEMI and UA then analyzed for various risk factors, angiographic patterns and severity of coronary artery disease. Results: Mean age of presentation was 59.3Å}12.8 years. Majority were male 317(75.7%). Most patients had STEMI 252 (60.1%) followed by NSTEMI 98 (23.4%) and UA 69 (16.5 %). Risk factors: smoking was present in 241 (57.5%), hypertension in 212 (50.6%), diabetes in 144 (34.4%), dyslipidemia in 58 (13.8%). Single-vessel disease was present in 34.6 % patients, double- vessel disease was present in 27.44 % patients and triple vessel disease was present in 26.3 % patients, left main disease in 1.4 % patients. Normal coronaries were present in 6.4% patients and minor coronary artery disease in 3.8 % patients. Conclusions: STEMI was the most common presentation. Three quarters of ACS were male patients. Smoking was most prevalent risk factor. Single vessel involvement was the most common CAG finding in all spectrum of ACS. Diabetic patients had more multivessel disease.

scholarly journals PATTERN OF CORONARY ARTERY DISEASES IN PATIENTS UNDER 40 YEARS OF AGE WITH ACUTE CORONARY SYNDROME

2021 ◽  
Vol 54 (2) ◽  
pp. 144-147
Author(s):  
Iram Jehan Balouch ◽  
Iftikhar Ahmed ◽  
Faiza Farooq ◽  
Syed Ahsan Raza ◽  
Najia Aslam Soomro ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Family History ◽  
Positive Family History ◽  
Young Patients ◽  
Coronary Artery Diseases ◽  
Coronary Syndrome ◽  
Single Vessel ◽  
History Of

Objectives: To determine the pattern of coronary artery diseases (CAD) in patients under 40 years of age with acute coronary syndrome (ACS) presenting at Hyderabad Satellite Center of National Institute of Cardiovascular Disease (NICVD), Pakistan. Methodology: This cross-sectional study was conducted at cardiology department of the NICVD, Hyderabad Satellite Center. Both male and female patients, between 18 to 40 years of age, diagnosed with acute coronary syndrome (ACS), and undergone coronary angiography were included in this study. Angiographic patterns in terms of extent of the disease (number of diseased vessels and localization of lesion) were assessed. Results: Total of 220 young patients included. Patients were predominantly male (91.8%) with the mean age of 35.3 ± 5 years. Smoking was observed 30.5% followed by hypertension (24.5%) and positive family history of CAD (19.1%). A majority of the patients (79.1%) were diagnosed as with ST-elevation myocardial infarction (STEMI) with anterior wall myocardial infarction (MI) as the most common (57.3%) type of MI. Most of the patients (70%) had single vessel diseases (SVD) with left anterior descending artery (LAD) as the most commonly diseases vessel (53.6%). Nine (4.1%) patients had significant left main disease and 6.4% had non-obstructive CAD. Conclusion: The common clinical presentation of ACS in younger patients is STEMI. Smoking is the commonest risk factor followed by hypertension and family history of CAD. More than 2/3rd of the young patients are expected to have single vessel diseases with LAD as the most commonly diseased vessel.

scholarly journals A study of risk factors and coronary angiographic profile in young patients with acute coronary syndrome

2020 ◽  
Vol 72 ◽  
pp. S6-S7
Author(s):  
Bodhisattya Roy Chaudhuri ◽  
Ram Pratap Saini ◽  
Sandeep Bansal
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Young Patients ◽  
Coronary Syndrome

Spontaneous coronary artery dissection in association with cabergoline therapy

2021 ◽  
Vol 14 (2) ◽  
pp. e240022
Author(s):  
Zia Saleh ◽  
Susan Koshy ◽  
Vaninder Sidhu ◽  
Andrea Opgenorth ◽  
Janek Senaratne
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Cardiac Risk ◽  
Artery Dissection ◽  
Spontaneous Coronary Artery Dissection ◽  
Coronary Artery Dissection ◽  
Coronary Syndrome ◽  
Ergot Derivative

Spontaneous coronary artery dissection (SCAD) is a rare but increasingly recognised cause of acute coronary syndrome. While numerous risk factors are associated with SCAD, one potential cause is coronary artery vasospasm. The use of cabergoline—an ergot derivative and dopamine agonist that may induce vasospasm—has been associated with SCAD in one other case report worldwide. Here, we describe SCAD in a 37-year-old woman on long-term cabergoline therapy with no other cardiac risk factors. Cabergoline-induced SCAD should be considered in patients presenting with an acute coronary syndrome who are treated with this medication.

Sign in / Sign up

Export Citation Format

Share Document