scholarly journals Microbiological profile and treatment outcome of emphysematous pyelonephritis: experience from two teaching hospitals of Bangladesh

2021 ◽  
Vol 11 (2) ◽  
pp. 108-111
Author(s):  
Juli Chowdhury ◽  
Nirmol Kumar Biswas ◽  
Shamima Sharmin Kanta ◽  
Muhammad Abdur Rahim ◽  
Wasim Md Mohosin Ul Haque ◽  
...  

Background: Emphysematous pyelonephritis (EPN) is a rare severe necrotizing infection of the renal parenchyma, collecting system and/or perirenal tissues. Patients with diabetes mellitus, renal stones and renal tract obstruction are at risk for development of EPN. Escherichia coli is the most common aetiological agent and treatment is aimed at infection control and interventions in appropriate cases. This study aimed to identify the aetiological agents responsible for EPN and the outcome of such cases. Methods: This observational study was done in BIRDEM General Hospital and Bangabandhu Sheikh Mujib Medical University over a period of three years (2011-2013). Twenty adult EPN cases were included in this study. Results: The mean age of the study participants was 59.2 years with female predominance (80%). Risk factors included diabetes mellitus (90%), renal stones (5%) and kidney transplant recipient (5%). Fever, loin pain and dysuria were common. Six patients had class 1 EPN, seven had class 2 disease, five had class 3 and two patients had class 4 EPN. Aetiological agents were cultured in 19 cases; E. coli in 12 (68%), Klebsiella in three (16%), Pseudomonus in two (11%) and Proteus and Enterococcus, one each (5% each). Carbapenems appeared as the most sensitive antibiotic. Along with antibiotic, half of the patients required interventions; percutaneous drainage in two, open drainage in two and six patients required nephrectomy. Regarding outcome, five patients died, 10 patients recovered completely and five patients recovered with residual renal dysfunction. Conclusion: E. coli was the most common causative agent in present EPN cohort. Outcome was poor. With improved management strategy, combining nephrologists, intervention radiologists and urologists – all together, a good outcome is expected. Birdem Med J 2021; 11(2): 108-111

2016 ◽  
Vol 27 (2) ◽  
pp. 78-80
Author(s):  
Tabassum Samad ◽  
Wasim Md Mohosin Ul Haque ◽  
Muhammad Abdur Rahim ◽  
MA Rahim ◽  
Sarwar Iqbal

Emphysematous pyelonephritis is a rare necrotizing renal parenchymal infection characterized by gas accumulation in kidneys with or without involving surrounding structures. Patients with diabetes mellitus are the usual sufferers. Here we depict a case of a young Bangladeshi diabetic lady who presented with abdominal pain and dysuria. Investigations confirmed left sided emphysematous pyelonephritis. She responded well to open drainage along with antibiotic coverage.Bangladesh J Medicine Jul 2016; 27(2) : 78-80


2014 ◽  
Vol 8 (3-4) ◽  
pp. 256 ◽  
Author(s):  
Antonio Tienza ◽  
Mateo Hevia ◽  
Imanol Merino ◽  
Jose Maria Velis ◽  
Ruben Algarra ◽  
...  

Emphysematous pyelonephritis is an acute necrotizing infection with gas in the kidney and perinephric space that carries a bad prognosis. Apart from its predisposing clinical entities, diabetes mellitus and immune-incompetence are quite common in patients with this infection. We report a case of a 53-year-old kidney transplant recipient diabetic male, suffering from recurrent fever, abdominal pain and nausea episodes. Immediate broad-spectrum antibiotics were administered and percutaneous drainage was performed after the diagnosis. The bacteria involved were Stahpylococcus epidermidis and Escherichia coli. After 4 weeks of antibiotic treatment and abscesses drainage, the case was resolved. Consecutives urine cultures and ultrasonographies confirm the complete resolution of the disease. We discuss the predisposing factors, clinical presentation and management.


2021 ◽  
pp. 004947552098364
Author(s):  
Muhammad Abdur Rahim ◽  
Ishrat Jahan ◽  
Tufayel Ahmed Chowdhury ◽  
Mehruba Alam Ananna ◽  
Sarwar Iqbal

Emphysematous pyelonephritis is a rare, severe form of necrotising infection of the kidneys and peri-nephric tissues with gas accumulation, occurring predominantly among patients with diabetes mellitus. Computed tomography scan can identify the distribution of gas in the affected reno-ureteral units and so establish and classify the diagnosis. We report a case of class 4 emphysematous pyelonephritis with emphysematous cystitis, occurring in a young Bangladeshi male, who presented with features of upper urinary tract infection. He had a background history of fibro-calculous pancreatic diabetes and chronic kidney disease. Imaging also revealed renal stones. He responded to conservative treatment.


2018 ◽  
Vol 5 (4) ◽  
pp. 822
Author(s):  
K. Shaik Anwar Hussain

Background: There is a complex interrelationship in the co-existence of thyroid dysfunction among diabetic patients and may be related to the development of cardiovascular diseases and other complications of long term metabolic derangements. The prevalence of thyroid dysfunction varies from 10 to 24% among diabetic patients. The objective of the present study was to determine the prevalence of thyroid dysfunction among the patients with diabetes mellitus in a tertiary care hospital at Puducherry, India.Methods: This retrospective study was conducted during June 2018 analysing the records of diabetes patients attending to the diabetes OPD, Department of General Medicine in the past one year and their association with thyroid dysfunction was studied.Results: Among the study participants (n=200), 14.5% (n=29) were Type I diabetics and 85.5% (n=171) were type II Diabetes patients. The prevalence of Thyroid Dysfunction (TD) among the study participants was 28.5% (n=57). The proportion of TD was higher among type 1 DM compared to type 2 (p<0.001).  The prevalence of subclinical hypothyroidism was more (n=7, 24.1%) among type 1DM compared to type II DM patients (p=0.05).Conclusions: There was a higher prevalence of TD among the diabetics. TD was more frequent among type 1 DM compared to Type 2 DM patients and the most frequent TD associated with diabetes was subclinical hypothyroidism.


Author(s):  
Nurillo Makhmudov ◽  
◽  
Zukhra Kosimova ◽  

In this study we report on our experience in treating two patients diagnosed with a rare disease of emphysematous pyelonephritis, who were admitted to the Urology department of Fergana Medical Institute during 2018. We provide details on each test conducted on patients, pre- and post-surgery. Our analysis shows that to prevent complications in patients with diabetes mellitus, dispensary observation with control of glucose levels, urine and blood tests is necessary.


2020 ◽  
Vol 5 (3) ◽  
pp. S189-S190
Author(s):  
M. Rahim ◽  
M. Ananna ◽  
T. Chowdhury ◽  
M. Mehfuz-E-Khoda ◽  
S. Iqbal ◽  
...  

2015 ◽  
Vol 14 (3) ◽  
pp. 305-307
Author(s):  
Kiran Kumar Singal ◽  
Neerja Singal ◽  
Bhaskar Gupta ◽  
Karun Puran Bhatti ◽  
Abhinav Gupta

Emphysematous pyelonephritis is a severe infection characterized by the presence of gas within the renal parenchyma tissues. It is a life threatening complication of bacterial interstitial nephritis, and it mainly occurs in patients with diabetes mellitus. We report a case of a 37 year old female who complained of fever and pain in left lumbar region on admission. Her past medical history included uncontrolled type 2 diabetes mellitus. On USG (ultrasonography), left kidney swollen and show echogenic linear specs with dirty shadowing suggestive of air in pelvicalyceal system (PCS). She was treated with intensive antibiotic therapy in high doses. On repeat USG there was marked reduction in air shadow in kidney and patient improved clinically.Bangladesh Journal of Medical Science Vol.14(3) 2015 p.305-307


2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii481-iii482
Author(s):  
Tabassum Samad ◽  
Wasim Haque ◽  
Muhammad Rahim ◽  
Shudhanshu Shaha ◽  
Mehruba Ananna ◽  
...  

2015 ◽  
Vol 5 (2) ◽  
pp. 122-124
Author(s):  
Muhammad Abdur Rahim ◽  
Mehruba Alam Ananna ◽  
Tabassum Samad ◽  
Tufayel Ahmed Chowdhury ◽  
Wasim Md Mohosinul Haque ◽  
...  

Emphysematous pyelonephritis is a rare, severe, necrotizing renal parenchymal infection characterized by gas accumulation in kidney(s) with or without involving surrounding tissues. Patients with diabetes mellitus are the usual sufferers. Here we describe a case history of a young Bangladeshi diabetic lady who presented with dysuria, fever and abdominal pain. Investigations confirmed left sided emphysematous pyelonephritis. She responded to and recovered with intravenous antibiotics.J Enam Med Col 2015; 5(2): 122-124


Author(s):  
Minoosh Shabani ◽  
Shervin Shokouhi ◽  
farnoosh masbough ◽  
Maryam Taleb Shoushtari ◽  
Atousa Hakamifard

We present a case of acute meningitis due to extended-spectrum beta-lactamase-producing E. coli in a patient with immune thrombocytopenic purpura and diabetes mellitus. This challenging entity is uncommon but has a high mortality rate. The exact mechanism for the pathogenesis is not obvious and needs further studies


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