scholarly journals The Correlation between Periodontal Diseases and Chronological Age among Type 2 Diabetes Mellitus Patients attending at National Healthcare Network (NHN) Mirpur Centre, Dhaka, Bangladesh

2013 ◽  
Vol 3 (2) ◽  
pp. 74-69 ◽  
Author(s):  
Shaikh Zakir Mahmud ◽  
Sheikh Mohammad Alif ◽  
Monowar Ahmad Tarafder ◽  
Sarder Mahmud Hossain
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Periodontal Diseases ◽  
Chronological Age ◽  
Diabetic Patients ◽  
National Healthcare ◽  
Healthcare Network ◽  
The Relationship

Background: The relationship between diabetes and periodontal diseases has been studied extensively during the past 50 years. Type 2 diabetes occurs mainly in people aged over 40, although it is affecting a growing number of young people. Patients with uncontrolled diabetes have poor resistance to infection with effects in mouth cavity and elsewhere in the body and show an unusually high susceptibility to periodontal diseases and increased susceptibility to acute lateral periodontal abscesses. Objective: This descriptive type of cross-sectional study was conducted to find out the relationship between periodontal diseases and chronological age among type 2 diabetes mellitus patients attending at National Healthcare Network (NHN) Mirpur Centre, Dhaka. Materials and Methods: A total 120 type 2 diabetic patients attended at diabetic centre for routine checkup over a period of six months from August 2011 to January 2012 who fulfilled the eligibility criteria were selected consecutively. Pre-tested semi structured interviewer administered questionnaires were used to collect the information. Cross tabulations and associations were determined by using the chi-square test and simple linear regression from Statistical Package for the Social Sciences where applicable. Results: Chronological age of the patients was significantly associated with the manifestation of periodontal diseases (p=0.004). Moreover, age was useful as a predictor of periodontal diseases as the correlation coefficients showed statistically significant result (p=0.008). In addition, for each year increase of age of the patients there was 0.20% increase of occurrence of periodontal diseases. Conclusion: Periodontal diseases can adversely affect the metabolic control of diabetes. Conversely, treatment of periodontal disease and reduction of oral inflammation may have a positive effect on the diabetic condition, although evidence for this remains somewhat equivocal. Birdem Med J 2013; 3(2): 74-79 DOI: http://dx.doi.org/10.3329/birdem.v3i2.17209

scholarly journals Sleep Characteristics in Diabetic Patients Depending on the Occurrence of Neuropathic Pain and Related Factors

2020 ◽  
Vol 17 (21) ◽  
pp. 8125
Author(s):  
Cristina Naranjo ◽  
María Dueñas ◽  
Carlos Barrera ◽  
Guillermo Moratalla ◽  
Inmaculada Failde
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Neuropathic Pain ◽  
Sleep Quality ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Diabetic Patients ◽  
The Relationship

This study aims to compare the sleep characteristics (structure and quality) in patients with type-2 diabetes mellitus with and without diabetic neuropathic pain (DNP), and to investigate the relationship of sensory phenotypes, anxiety, and depression with sleep quality in DNP patients. A cross-sectional study was performed in patients with type-2 diabetes mellitus and neuropathy. Patients were classified into two groups—with or without neuropathic pain—according to the “Douleur Neuropathique-4 (DN4)” scale. Sleep characteristics and quality (Medical Outcomes Study—MOS-sleep), pain phenotype (Neuropathic Pain Symptom Inventory—NPSI), mood status (Hospital Anxiety and Depression scale—HADS), pain intensity (Visual Analogue Scale—VAS), and quality of life (SF-12v2) were measured. The sample included 130 patients (65 with DNP). The mean scores in all the dimensions of the MOS-sleep scale were higher (more disturbances) in the DNP patients. Higher scores in anxiety or depression, greater intensity of pain or a higher score in the paroxysmal pain phenotype were associated with lower sleep quality in DNP patients. A shorter duration of the diabetes and lower levels of glycated hemoglobin were also associated with lower sleep quality. The results show the relationship between DNP and sleep quality, and the importance of assessing sensory phenotypes and mental comorbidities in these patients. Taking these factors into consideration, to adopt a multimodal approach is necessary to achieve better clinical results.

scholarly journals The relationship between periodontite and diabetes mellitus type ii facing the new classification of periodontal diseases: literature review

2020 ◽  
Vol 68 ◽  
Author(s):  
Lívia Maria Lopes de OLIVEIRA ◽  
Lívia Mirelle BARBOSA
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Literature Review ◽  
Periodontal Disease ◽  
Periodontal Diseases ◽  
New Classification ◽  
The Relationship

ABSTRACT Periodontal disease and type 2 diabetes mellitus are considered chronic diseases that at their core have a deep relationship with inflammation. It is assumed that there is a bidirectional relationship between periodontal disease and type 2 diabetes mellitus. It is estimated that approximately 10% of the world’s population is affected by periodontal disease, in its most severe form, almost the same percentage estimated for people with diabetes, which is considered a 21st century emergency. The World Workshop for the Classification of Periodontal and Peri-implant Diseases and Conditions took place from September 9-11, 2017. The aim of this study is to analyze the results of this workshop with regard to the relationship between periodontal diseases/conditions and diabetes mellitus, in addition to conducting an integrative review on the topic. A literature review was conducted, using the Medline electronic databases via Pubmed, Scientific Electronic Library Online, Scientific and Technical Literature of Latin America and the Caribbean and Virtual Health Library. A new classification of periodontal disease included tools for individual assessment of the patient and recognizing risk factors that might negatively interfere in response to treatment. The occurrence of metabolic lack of control in periodontal patients with type 2 diabetes mellitus is now considered a factor of great importance for the assessment of individual susceptibility to the progression of periodontitis. Diabetes is believed to promote a hyper inflammatory response to bacterial challenge by modifying the tissue response of periodontal tissues.

scholarly journals The Relationship between Plasma Taurine Levels and Diabetic Complications in Patients with Type 2 Diabetes Mellitus

Biomolecules ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 96 ◽  
Author(s):  
Duygu Sak ◽  
Fusun Erdenen ◽  
Cuneyt Müderrisoglu ◽  
Esma Altunoglu ◽  
Volkan Sozer ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Complications ◽  
Active Role ◽  
Diabetic Complication ◽  
Diabetic Patients ◽  
Healthy Control ◽  
The Relationship

Background: Taurine has an active role in providing glucose homeostasis and diabetes causes a decline in taurine levels. This paper investigates the relationship between taurine and diabetic complications, patients’ demographic features, and biochemical parameters. Methods: Fifty-nine patients with type 2 diabetes mellitus (T2DM), and 28 healthy control subjects between the ages of 32 and 82 were included in the study. The mean age of subjects was 55.6 ± 10.3 and mean diabetes duration was 10.2 ± 6.0 years. The most commonly accompanying comorbidity was hypertension (HT) (64.5%, n = 38), and the most frequent diabetic complication was neuropathy (50.8%, n = 30). Plasma taurine concentrations were measured by an enzyme-linked immunoassay (ELISA) kit. Results: Plasma taurine concentrations were significantly lower in diabetic patients (0.6 ± 0.1 mmol/L) than controls (0.8 ± 0.2 mmol/L) and in hypertensive (0. 6 ± 0.1 mmol/L) patients (p = 0.000, p = 0.027 respectively). Conclusion: Plasma taurine levels were decreased in patients with T2DM and this was not related to FBG, HbA1c, and microalbuminuria. With regard to complications, we only found a correlation with neuropathy. We suggest that taurine levels may be more important in the development of diabetes; however, it may also have importance for the progression of the disease and the subsequent complications. We further assert that taurine measurement at different times may highlight whether there is a causal relationship in the development of complications.

scholarly journals Is Uric Acid elevation a random finding or a causative agent of diabetic nephropathy?

2019 ◽  
Vol 65 (9) ◽  
pp. 1155-1160 ◽  
Author(s):  
Mehmet Zahid Kocak ◽  
Gulali Aktas ◽  
Tuba T. Duman ◽  
Burcin M. Atak ◽  
Haluk Savli
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Diabetic Nephropathy ◽  
Study Groups ◽  
Diabetic Patients ◽  
Study Participants ◽  
The Relationship

SUMMARY OBJECTIVE In this study, we aimed to analyze the relationship between serum uric acid (UA) and microalbuminuria as a marker of renal injury in type 2 diabetes mellitus. METHODS A total of 100 patients with type 2 diabetes mellitus were enrolled in the study. Participants were divided into two groups according to the urinary microalbumin/creatinine ratio: diabetic nephropathy and non-nephropathy group. UA and microalbuminuria were compared between the study groups. RESULTS Serum UA levels of diabetic nephropathy patients were significantly higher than those in the non-nephropathy group (UA in patients with diabetic nephropathy groups: 6.3 (1.82) mg/dl, UA in patients of the non-nephropathic group: 4.85 (1.92) mg/dl) (p<0.001). There was a correlation between microalbuminuria and UA (r=0.238). This correlation was statistically significant (p=0.017). CONCLUSION UA levels may be an important predictor of nephropathy in diabetic patients.

scholarly journals The Patterns of Oral Diseases among Type 2 Diabetes Mellitus Patients Attending at National Healthcare Network (NHN) Mirpur Centre, Dhaka, Bangladesh

2013 ◽  
Vol 3 (2) ◽  
pp. 5-11
Author(s):  
SZ Mahmud ◽  
A Mustakim ◽  
A Taleb
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Alveolar Bone ◽  
Control Group ◽  
Case Group ◽  
Oral Diseases ◽  
National Healthcare ◽  
Healthcare Network

Background: The term “diabetes mellitus” describes a group of disorders characterized by elevated levels of glucose in the blood and abnormalities of carbohydrate, fat and protein metabolism. A number of oral diseases and disorders are associated with diabetes mellitus and, gingivitis and periodontitis have been identified as possible risk factors for poor metabolic control in subjects with diabetes. Objective: To assess oral diseases in type 2 diabetes mellitus patients and controls who attended at National Healthcare Network (NHN), Mirpur Centre, Dhaka, Bangladesh. Materials & Methods: A total of 100 subjects - 47 diabetics and 53 non-diabetics fulfilled the eligibility criteria were selected consecutively. Pretested semi-structured interviewer administered questionnaire and check list were utilized to assess the main objective of the study. Cross tabulations and associations were found out by using Chi-square Test  Statistical Package for the Social Sciences was used for data analysis. Results: The cases were relatively older than the controls with mean age of the subjects in case group being significantly higher than that in the control group (p < 0.001), but the groups were not statistically different in terms of sex (p = 0.194). More than two-thirds (68.1%) of the cases and 52.8% of the controls exhibited burning mouth syndrome (p = 0.120). Candidiasis and dental caries were associated, more than in case control group (p = 0.020 and p < 0.001 respectively). Gingivitis was found significantly higher in case group compared to control group (78.7% vs. 37.7%, p < 0.001). In the case group, nearly half (48.9%) had periodontitis, 29.8% alveolar bone loss and 27.7% collagen metabolism, as opposed to none in the control group (p < 0.001). Conclusion: Oral diseases are multi-factorial and the factors responsible for these diseases are preventable. Dentists must be familiar with techniques to diagnose, treat and prevent oral diseases in patients with diabetes. DOI: http://dx.doi.org/10.3329/bjdre.v3i2.16602 Bangladesh Journal of Dental Research & Education Vol.3(2) 2013: 5-11

Association of Major Dietary Patterns with General and Abdominal Obesity in Iranian Patients with Type 2 Diabetes Mellitus

2015 ◽  
Vol 85 (3-4) ◽  
pp. 145-155 ◽  
Author(s):  
Marjan Ghane Basiri ◽  
Gity Sotoudeh ◽  
Mahmood Djalali ◽  
Mohammad Reza Eshraghian ◽  
Neda Noorshahi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Abdominal Obesity ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Diabetic Patients ◽  
General Obesity ◽  
Healthy Dietary Pattern

Abstract. Background: The aim of this study was to identify dietary patterns associated with general and abdominal obesity in type 2 diabetic patients. Methods: We included 728 patients (35 - 65 years) with type 2 diabetes mellitus in this cross-sectional study. The usual dietary intake of individuals over 1 year was collected using a validated semi-quantitative food frequency questionnaire. Weight, height, and waist circumference were measured according to standard protocol. Results: The two major dietary patterns identified by factor analysis were healthy and unhealthy dietary patterns. After adjustment for potential confounders, subjects in the highest quintile of the healthy dietary pattern scores had a lower odds ratio for the general obesity when compared to the lowest quintile (OR = 0.45, 95 % CI = 0.26 - 0.79, P for trend = 0.02), while patients in the highest quintile of the unhealthy dietary pattern scores had greater odds for the general obesity (OR = 3.2, 95 % CI = 1.8 - 5.9, P for trend < 0.001). There were no significant associations between major dietary patterns and abdominal obesity, even after adjusting for confounding factors. Conclusion: This study shows that in patients with type 2 diabetes mellitus, a healthy dietary pattern is inversely associated and an unhealthy dietary pattern is directly associated with general obesity.

ESTIMATION OF SERUM FERRITIN LEVELS IN TYPE 2 DIABETIC PATIENTS AND ITS RELATION WITH HbA1C LEVEL.

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Shah Namrata Vinubhai ◽  
Pardeep Agarwal ◽  
Bushra Fiza ◽  
Ramkishan Jat
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Sugar ◽  
Serum Ferritin ◽  
Inflammatory Marker ◽  
Control Group ◽  
Diabetic Patients ◽  
Positive Correlation

Background: Serum ferritin is known as an index for body iron stores also as an inflammatory marker and it is influenced by several disease. We were looking for a correlation between HbA1c and S. Ferritin in type 2 DM. Methodology: The present study a total of 150 participants were enrolled of which 100 were confirmed cases of Type 2 Diabetes Mellitus and rest 50 age and sex matched healthy subjects constituted the control group. All were screened for HbA1c, Fasting blood sugar, Post prandial blood sugar and S.Ferritin. Results: A highly significant variation and positive correlation was observed with respect to S.Ferritin and HbA1c levels. Mean S.Ferritin was high in the subgroup with poor glycemic control. Conclusion: The fasting, post prandial sugar levels, HbA1c and S.Ferritin were significantly higher in the diabetic subjects. This study shows a positive correlation between HbA1c and S. Ferritin levels. So we can conclude that in diabetic patients S. Ferritin may serve as an independent marker of poor glycemic and metabolic control. Keywords: Serum ferritin, Type 2 Diabetes Mellitus, HbA1c.

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