scholarly journals Steroid, Triterpenoid and Phenylpropanoid From Stereospermum Suaveolens (Roxb.) DC Growing in Bangladesh

2021 ◽  
Vol 50 (4) ◽  
pp. 1191-1194
Author(s):  
- Md Moniruzzaman ◽  
Md Ruhul Kuddus ◽  
Md Al Amin Sikder ◽  
AM Sarwaruddin Chowdhury ◽  
Mohammad A Rashid
Keyword(s):  
Physical Properties ◽  
Plant Species ◽  
Chromatographic Separation ◽  
Methanol Extract ◽  
Stem Bark ◽  
Separation And Purification ◽  
Chemical Structures ◽  
Nmr Data ◽  
Phytochemical Investigation ◽  
Methoxycinnamic Acid

The study was carried out to investigate the composition of natural compounds of methanol extract of leaf and stem bark of Stereospermum suaveolens (Roxb.) DC by repeated chromatographic separation and purification processes over silica gel. The phytochemical investigation resulted in the isolation of a total of three compounds, which were identified as stigmasterol (1), β-amyrin (2) and 4-methoxycinnamic acid (3). The chemical structures of the isolated compounds were elucidated by analyses of their physical properties, acquired 1H NMR data and comparison with published reports. Among these, compounds 2 and 3 are first report of their isolation from this plant species. Bangladesh J. Bot. 50(4): 1191-1194, 2021 (December)

scholarly journals Phytochemical Investigation of Calophyllum inophyllum L.

2019 ◽  
Vol 18 (2) ◽  
pp. 179-182
Author(s):  
Quazi Sufia Islam ◽  
Md Hossain Sohrab ◽  
Suraiya Sharmin ◽  
Choudhury Mahmood Hasan
Keyword(s):  
Secondary Metabolites ◽  
Chromatographic Separation ◽  
Stem Bark ◽  
Separation And Purification ◽  
Calophyllum Inophyllum ◽  
Nmr Data ◽  
Phytochemical Investigation

Repeated chromatographic separation and purification of the dichloromethane-methanol (1:1) extract of the stem bark of Calophyllum inophyllum led to the isolation of four secondary metabolites which were identified as β-friedelin (1), α-friedelan-3-ol (2), 4-hydroxyxanthone (3) and stigmast-5-en-3-one (4) by analysis of their NMR data and comparison with published values Dhaka Univ. J. Pharm. Sci. 18(2): 179-182, 2019 (December)

scholarly journals Isolation of lupeol from the stem bark of Leptadenia hastata (Pers.) Decne

2020 ◽  
Vol 24 (10) ◽  
pp. 1835-1838
Author(s):  
M.M. Mailafiya ◽  
U.U. Pateh ◽  
H.S. Hassan ◽  
M.I. Sule ◽  
A.H. Bila ◽  
...  
Keyword(s):  
Spectral Data ◽  
Column Chromatography ◽  
Methanol Extract ◽  
2D Nmr ◽  
Stem Bark ◽  
Hexane Fraction ◽  
Solid Substance ◽  
Phytochemical Screening ◽  
Nmr Data ◽  
Crude Methanol Extract

Dried stem bark powder of Leptadania hastata was subjected to maceration with methanol to afford crude methanol extract, which was partitioned with n-hexane, ethylacetate, chloroform and n- butanol to afford different their respective fractions. Extensive phytochemical screening of the n-hexane fraction using column chromatography resulted to the isolation of a white solid substance. The substance was identified as of lupeol using IR, 1D – NMR, 2D – NMR data and by comparison with reference spectral data. Keywords: Leptadenia hastata, Isolation, Lupeol, 1D – NMR, 2D – NMR

scholarly journals Sterol and triterpenoids from Hygrophila schulli Buch.-Ham.

2018 ◽  
Vol 44 (2) ◽  
pp. 319-321
Author(s):  
Md Abu Suflan ◽  
Fatema Begum ◽  
Mohammad Rashedul Haque ◽  
Choudhury Mamood Hasan ◽  
Mohammad Abdur Rashid
Keyword(s):  
1H Nmr ◽  
Chromatographic Separation ◽  
Methanol Extract ◽  
Chemical Constituents ◽  
Published Data ◽  
Separation And Purification ◽  
First Report ◽  
Spectral Evidence ◽  
Whole Plants

The methanol extract of whole plants of Hygrophila schulli Buch.-Ham. was subjected to repeated chromatographic separation and purification processes to isolate its chemical constituents. A total of three compounds were isolated which have been characterized as stigmasterol, lupeol and lup-20(29)-ene-3β,23- diol on the basis of 1H NMR spectral evidence and confirmed by comparing with published data, as well as co-TLC in case of stigmasterol and lupeol. This is the first report of lup-20(29)-ene-3β,23-diol from this plant.

scholarly journals The phytochemical investigation from n-hexane extract of the lichen Roccella montagnei

2021 ◽  
Vol 24 (2) ◽  
pp. first
Author(s):  
Thu Thi-Hoai Nguyen ◽  
Duong Thuc Huy
Keyword(s):  
Ethyl Acetate ◽  
Hexane Extract ◽  
Published Data ◽  
Chemical Structures ◽  
Nmr Data ◽  
Phytochemical Investigation ◽  
Partition Method ◽  
First Time ◽  
Ethyl Acetate Extracts

Introduction: R occella montagnei is widely distributed in subtropical regions. As the continuous study on the hexane extract of Roccella montagnei lichen, the isolation and structural determination of five compounds were addressed. Method: The crude extract was obtained from the dried lichen powder's extraction at room temperature. The n-hexane, n-hexane-ethyl acetate, and ethyl acetate extracts were obtained by the liquid-liquid partition method. The organic compounds were isolated from n-hexane extract by silica gel and Sephadex LH-20 column chromatography. Their chemical structures were identified by the NMR and HR-ESI-MS data analysis and the comparison of their NMR data with the published data. Results: Five compounds were isolated and chemically structural identified, consisting of 3b -hydroxy-7a-methoxystigmast-5-ene (1), sekikaic acid (2), lichenxanthone (3), (+)-6,8-dihydroxy-3-propyl-3,4-dihydroisocoumarin (4), and ar-turmerone (5). Conclusion: To the best of our knowledge, except 3 which was reported from this species for the first time, four isolated compounds left did not known to be present in Roccella genus before.

scholarly journals Phytochemical Investigation of Schleichera oleosa (Lour.) Oken Leaf

2021 ◽  
Vol 24 (1) ◽  
pp. 33-36
Author(s):  
Noushin Anjum ◽  
Md Jamal Hossain ◽  
Mohammad Rashedul Haque ◽  
Akhtaruzzaman Chowdhury ◽  
Mohammad A Rashid ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Medicinal Plant ◽  
Betulinic Acid ◽  
Methanol Extract ◽  
Folk Medicine ◽  
Pharmaceutical Journal ◽  
Nmr Data ◽  
Phytochemical Investigation ◽  
Schleichera Oleosa ◽  
Soluble Fractions

Schleichera oleosa (Lour.) Oken. is a medicinal plant of Bangladesh with enormous traditional applications in folk medicine. The current study was designed to isolate the secondary metabolites by successive chromatographic separation of n-hexane and dichloromethane soluble fractions of a methanol extract of leaves of S. oleosa. A total of four compounds were separated and identified as 5,7-dihydroxy-4'-methoxyflavone, stigmasterol, lupeol and betulinic acid. The structures of the isolated compounds were elucidated by analysis of their 1H NMR data and comparison with published values. Bangladesh Pharmaceutical Journal 24(1): 33-36, 2021

scholarly journals Triterpenoids from Phyllanthus acidus (L.) Skeels

2019 ◽  
Vol 2 (2) ◽  
pp. 71-75 ◽  
Author(s):  
Huy Thuc Duong ◽  
Hung Huu Nguyen ◽  
Tuyet Thi Anh Nguyen ◽  
Hao Xuan Bui
Keyword(s):  
Plant Species ◽  
Spectroscopic Analysis ◽  
Folk Medicine ◽  
Ethanol Extract ◽  
Stem Bark ◽  
Nmr Data ◽  
Phyllanthus Acidus ◽  
Anti Inflammatory ◽  
First Time

The genus Phyllanthus (Phyllanthaceae) includes more than 900 plant species found in tropical and subtropical regions. Many of these species are widely used in folk medicine. The leaves, roots, and stem bark of Phyllanthus acidus (L.) Skeels have been used in Vietnamese folk medicine as an antibacterial, antiviral, analgesic, anti-inflammatory, neuroprotective, hepatoprotective, antifibrotic. From the ethanol extract of the roots of Phyllanthus acidus (L.) Skeels growing in Binh Thuan province, six compounds phyllanthol (1), glochidone (2), lupeol (3), glochidonol (4), 􀀱-lupene (5), and spruceanol (6) were isolated. Their structures were established by extensive spectroscopic analysis as well as comparison with NMR data in the literatures. This is the first time that compounds 4-6 were found in Phyllanthus acidus (L.) Skeels.

scholarly journals Triterpenoids from Vitellaria paradoxa Stem Barks Reduce Nitrite Levels in LPS-Stimulated Macrophages

Plants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1006
Author(s):  
Carmina Sirignano ◽  
Pascal Nadembega ◽  
Ferruccio Poli ◽  
Barbara Romano ◽  
Giuseppe Lucariello ◽  
...  
Keyword(s):  
Ethyl Acetate Extract ◽  
2D Nmr ◽  
Stem Bark ◽  
Inhibitory Effect ◽  
Vitellaria Paradoxa ◽  
Free Alcohol ◽  
Nmr Data ◽  
Phytochemical Investigation ◽  
New Compounds

Vitellaria paradoxa C. F. Gaertn is widely used in African traditional medicine as an anti-inflammatory remedy to treat rheumatism, gastric problems, diarrhea, and dysentery. The phytochemical investigation of the ethyl acetate extract of V. paradoxa stem bark collected in Burkina Faso led to the isolation of eight known and two triterpenes undescribed to date (7 and 10), in the free alcohol form or as acetyl and cinnamyl ester derivatives. The stereostructures of the new compounds were elucidated using HR-ESIMS and 1D and 2D NMR data. The isolated compounds were evaluated in vitro for their inhibitory effect on nitrite levels on murine macrophages J774 stimulated with the lipopolysaccharide (LPS). Among all the compounds tested, lupeol cinnamate (3) and betulinic acid (5) showed a beneficial effect in reducing nitrite levels produced after LPS stimulation.

scholarly journals Isolation and characterization of Stigmasta-7, 22-dien-3-ol (α-Spinasterol) from Entada africana stem bark crude extract

2019 ◽  
Vol 4 (3) ◽  
pp. 85
Author(s):  
A. Kwajia ◽  
H.M. Adamub ◽  
I.Y. Chindob
Keyword(s):  
Crude Extract ◽  
Spectroscopic Data ◽  
Soluble Fraction ◽  
Stem Bark ◽  
Literature Analysis ◽  
Bark Sample ◽  
Isolation And Characterization ◽  
Nmr Data ◽  
Phytochemical Investigation

The phytochemical  investigation of the stem bark extracts of Entada africana led to the isolation and characterization of Stigmasta-7,22-dien-3-ol from the dichloromethane soluble portion of acetone/methanol (1:1v/v) crude extract. The powdered stem bark sample of Entada africana was defatted with hexane and extracted with acetone/methanol (1:1v/v) mixture. The dichloromethane soluble fraction was purified on a low pressure column containing silica gel 60 (60-200 mesh). The purification afforded an isolate coded Enac3 (85 mg) with Rf value of 0.404 in hexane/ethyl acetate (4:1). The isolate was characterized using IR, NMR data and in comparison with literature. Analysis of spectroscopic data and literature comparison suggests Enac3 as stigmasta-7, 22-dien-3-ol. The isolation of stigmasta-7, 22-dien-3-ol from the stem bark of Entada africana suggests the presence of useful bioactive principles which could be exploited for medicinal purposes.

scholarly journals Stigmasterol and Stigmasterone from Methanol Extract of Calophyllum soulattri Burm. F. Stem Bark

2021 ◽  
Vol 24 (4) ◽  
pp. 108-113
Author(s):  
Surya Dewi Marliyana ◽  
Fajar Rakhman Wibowo ◽  
Desi Suci Handayani ◽  
Triana Kusumaningsih ◽  
Venty Suryanti ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Methanol Extract ◽  
Biological Activities ◽  
Stem Bark ◽  
Bark Extract ◽  
Solvent Fractionation ◽  
Phytochemical Investigation ◽  
Stem Bark Extract ◽  
Flash Column Chromatography ◽  
Vacuum Liquid Chromatography

Stigmasterol and Stigmasterone from Methanol Extract of Calophyllum soulattri Burm. F. Stem Bark. Calophyllum soulattri Burm. F. has been widely used for herbal medicine. Phytochemical investigation of C. soulattri contains a secondary metabolite of the steroid class. Steroid compounds have various biological activities, such as anti-inflammatory, antioxidant, antiproliferative, antibacterial, antimalarial, and anticancer. Two secondary metabolites steroids have been isolated and identified from the stem bark extract of C. soulattri. Isolation was carried out through the extraction (maceration), fractionation, and purification stages. Maceration is carried out using methanol as a solvent. Fractionation was carried out by vacuum liquid chromatography (VLC), and purification was by flash column chromatography. Identification of combined fractions and determination of pure isolates were used through thin-layer chromatography (TLC). The solvent used in the chromatography methods was a mixture of n-hexane and ethyl acetate. The structure isolates were identified by FTIR, 1H NMR, and 13C NMR and compared with literature data. Secondary metabolites steroids that have been isolated are identical compounds to stigmasterol and stigmasterone.

scholarly journals Isolation and identification of euphol and β-sitosterol from the dichloromethane extracts of Synadenium glaucescens

2016 ◽  
Vol 5 (3) ◽  
pp. 100-104
Author(s):  
Vitus A. Nyigo ◽  
◽  
Xolani Peter ◽  
Faith Mabiki ◽  
Hamisi M. Malebo ◽  
...  
Keyword(s):  
Plant Species ◽  
13C Nmr ◽  
Isolation And Identification ◽  
Chemical Structures ◽  
Nmr Data ◽  
First Time

Purification of dichloromethane extract from root barks and leaves of Synadenium glaucescens respectively resulted into the isolation of two compounds namely Euphol and β-sitosterol. Chemical structures were established mainly by using 1H an d 13C NMR data and by comparing current NMR data with those reported in the literature. Both compounds are known and have been isolated from other plant species but are being reported from this plant species for the first time.

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