scholarly journals Validity of KAtex Test for the Diagnosis of Visceral leishmaniasis in Endemic Region of Bangladesh

2015 ◽  
Vol 1 (1) ◽  
pp. 8-11
Author(s):  
Zakir Hossain Habib ◽  
Afzalunnessa Binte Lutfor ◽  
Sanya Tahmina Jhora ◽  
Imtiaz Ahmed ◽  
Hasina Akhter
Keyword(s):  
High Sensitivity ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Endemic Region ◽  
Cross Sectional ◽  
Medical College ◽  
Kala Azar ◽  
Blood And Urine Samples ◽  
One Year ◽  
Age And Sex

Background: Early diagnosis of Kala-azar is of prime importance to reduce the transmission of the disease. Objective: The purpose of the present study was to evaluate KAtex test for the diagnosis of Kala-azar. Methodology: This cross sectional study was carried out in Department of Microbiology at Sir Salimullah Medical College, Dhaka for a period of one year from July 2007 to June 2008. Patients were selected clinically form all age and sex group hailing from endemic region of Mymensingh in a semi purposive manner excluding those who have already started taking medicine or refused to participate in the study.  Blood and urine samples were collected from the patients admitted in Sir Salimullah Medical College, Dhaka, Mymensingh Medical College and Bhaluka Health Complex, Mymensingh.  Result: Among 150 of the clinically selected patients, total 100 cases were confirmed to be positive for Kala-azar by rK39 ICT test. Age and sex matched 25 healthy persons each from endemic and non-endemic area was taken as control. Among the 100 sero-confirmed cases KAtex was positive in 87 (sensitivity of 87%). Among the 50 controls none were positive by KAtex test resulting in specificity of these tests 100% and 98% respectively. Conclusion: KAtex test has high sensitivity and specificity for the diagnosis of Kala-azar patients at endemic region of Bangladesh.Bangladesh J Infect Dis 2014;1(1):8-11

scholarly journals Diagnosis of Kala-azar by rK39 based ELISA and KAtex

KYAMC Journal ◽  
2017 ◽  
Vol 6 (1) ◽  
pp. 574-578 ◽  
Author(s):  
Zakir Hossain Habib ◽  
Imtiaz Ahmed ◽  
Hasina Akhter ◽  
Hafiza Akhter ◽  
Sanya Tahmina Jhora ◽  
...  
Keyword(s):  
Endemic Area ◽  
Cross Sectional Study ◽  
Elisa Test ◽  
Confirmatory Test ◽  
Sectional Study ◽  
Cross Sectional ◽  
Kala Azar ◽  
One Year ◽  
Healthy Persons ◽  
Age And Sex

This cross sectional study was carried out in SSMC for a period of one year from July 2007 to June 2008 to evaluate rK39 based ELISA and KAtex tests for diagnosis of Kala-azar. Total 150 patients were selected clinically. For this study rK39 ICT was regarded as confirmatory test according to national guideline. Among 150, total 100 cases were confirmed to be positive for Kala-azar by rK39 ICT test. Age and sex matched 25 healthy persons each from endemic and non-endemic area were taken as control. Among the 100 sero confirmed cases KAtex was positive in 87 (sensitivity of 87%) while ELISA was positive in 98 cases (sensitivity 98%). Among the 50 controls none were positive by KAtex test while 1 (one) ELISA test was positive resulting in specificity of these tests 100% and 98% respectively. The result of the study clearly showed superiority of rK39 antigen based ELISA in respect of sensitivity and KAtex in respect of specificity.KYAMC Journal Vol. 6, No.-1, Jul 2015, Page 574-578

scholarly journals Comparison of KAtex, Bone Marrow Aspiration and DAT for the Diagnosis of Visceral Leishmaniasis

2019 ◽  
Vol 6 (1) ◽  
pp. 12-15
Author(s):  
Ishrat Sharmin ◽  
AKM Quamruzzaman ◽  
Rezina Parveen ◽  
M Abdulah Yusuf ◽  
Rashida Akter Khanam
Keyword(s):  
Bone Marrow ◽  
Visceral Leishmaniasis ◽  
Leishmania Donovani ◽  
Bone Marrow Aspiration ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Kala Azar ◽  
History Of ◽  
One Year

Background: Newly developed KAtex test can be used as a non invasive tool for diagnosis of Kala-azar. Objectives: The aim of the present study was to compare KAtex, Bone marrow aspiration and DAT to diagnose VL. Methodology: This cross-sectional study was carried out in the Department of Microbiology at Dhaka Medical College, Dhaka, Bangladesh in collaboration with the Department of Parasitology, Institute of Epidemiology, Disease Control and Research (IEDCR), Dhaka, Bangladesh for a period of one year. Clinically suspected Kala-azar (VL) cases of different age and sex attending IEDCR, Dhaka from different Kala-azar endemic areas of Bangladesh were selected for this study. Patients having fever for more than 2 weeks, with or without splenomegaly, having history of loss of body weight following onset of fever were clinically suspected as Kala-azar cases. Microscopy and culture was performed in bone marrow (BM). KAtex was performed with urine sample. Agglutination of sensitized latex indicated presence of Leishmania donovani antigen in urine and thereby visceral leishmaniasis. No agglutination indicates absence of antigen in urine. DAT was done with serums of all cases. Result: Among 130 clinically suspected VL cases, 70 (53.85%) cases were BM positive and 60(46.15%) cases were BM negative. All the 70 BM positive cases were positive by KAtex and DAT. Among 60 BM negative cases, 15 were positive by KAtex and 23 were positive by DAT. The sensitivity of KAtex was 100.0% and specificity was 75.0%. The sensitivity of DAT was 100.0% and specificity is 61.6%. Conclusion: In conclusion, KAtex test is a good diagnostic tool for the detection of VL in comparison with DAT. Bangladesh Journal of Infectious Diseases, June 2019;6(1):12-15

scholarly journals Study to Determine the Incidence of High HbA1c in Patients with Ischemic Stroke at Bilawal Medical College, Kotri, Sindh, Pakistan

2021 ◽  
pp. 20-24
Author(s):  
Atif Ahmed ◽  
Kuldeep Poorani ◽  
Mohammad Amjad Kalhoro ◽  
Nisar Ahmed Khokar ◽  
Abdul Ghaffar Dars
Keyword(s):  
Ischemic Stroke ◽  
Blood Glucose ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
College Hospital ◽  
Cross Sectional ◽  
Ischemic Disease ◽  
Medical College ◽  
Cerebral Ischemic ◽  
One Year

Aim: To study the incidence of HbA1c elevation in patients with ischemic stroke whose blood glucose levels were normal within the last six months. Study Design: A cross-sectional study. Place and Duration: This cross-sectional study of the 96 patients with cerebral ischemic disease selected from the internal medicine department of Bilawal medical college Hospital Kotri, Sindh, Pakistan for one-year duration from August 2019 to August 2020. Methods: Crossectional study was conducted in the internal medicinal department of Bilawal Medical college Hospital, Kotri Sindh, Pakistan for the period of one year from August 2019 to August 2020. Total 96 study subjects were selected with cerebral ischemic disease, 62 were males and 34 were females. Many factors such as age more than 20 years, ischemic stroke and RBG (Random Blood Glucose) were also evaluated from each participant. SPSS 23.00 version was used for statistical analysis of research data. Results: 57.01 ± 13.4 years was the mean age of the patients. 62 (64.6%) patients were male and 34 (35.4%) were female. The male to female ratio was 2:1. HbA1c was elevated in 35 (36.5%) of 96 patients, while 61 (63.5%) had normal HbA1c.  The distribution of HbA1c elevation by gender showed that 20 (57.1%) patients with elevated HbA1c were men and 15 (42.9%) were women. Forty-three (70.5%) of 61 patients with normal HbA1c were male and 18 (29.5%) were female. Conclusion: it was concluded that glycated haemoglobin plays an important role for reducing the macro complication of Diabetes and the major macro complication observed was cerebral ischemic stroke among the people with elevated HbA1c.

scholarly journals Extent of Mesoappendix of Vermiform Appendix in Bangladeshi People

1970 ◽  
Vol 4 (1) ◽  
pp. 20-23 ◽  
Author(s):  
Md Mahbubur Rahman ◽  
Mohsin Khalil ◽  
Mansur Khalil ◽  
Seheli Zannat Sultana ◽  
Sabina Mannan ◽  
...  
Keyword(s):  
Sampling Technique ◽  
Vermiform Appendix ◽  
Cross Sectional Study ◽  
Postmortem Examination ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Bangladeshi Population ◽  
Pelvic Position ◽  
Age And Sex

Background: The mesentery of the appendix extends almost to the appendicular tip along the whole tube or may not be to the tip. The mesoappendix has a free border which carries the blood supply to the organ. Failure of the mesoappendix to reach the tip probably reduces the vascularization of the tip of the organ making it more liable to become gangrenous and hence early perforation occurs during inflammation. Objective: This cross sectional study was carried out to advance our knowledge regarding the extent of mesoappendix in Bangladeshi people and also to find out the variations in the anatomical positions of the vermiform appendix in Bangladeshi population and their distribution according to the sex. Methods: A total of 100 (60 male and 40 female) specimens of vermiform appendix were collected of different age and sex during postmortem examination in the morgue of Mymensingh Medical College from July 2006 to June 2007. Data was collected by convenient sampling technique. Results: In this study pelvic position of the vermiform appendix were common in both sexes. The two thirds extension of mesoappendix was found in 45% cases where as in pelvic position it was 26 (14 male and 12 female) cases. Half and whole extension of mesoappendix were found in 31% and 24% cases respectively. Among half extension of mesoappendix, retrocaecal position were found to be more (12) than other positions. In whole extension of vermiform appendix pelvic position were found to be common (16) than others. Conclusion: This study provides certain basic information of extent of mesoappendix of vermiform appendix of Bangladeshi population which is responsible for vascularization of the organ and severity during inflammation. Key words: Vermiform appendix, Mesoappendix   DOI: 10.3329/jbsp.v4i1.4065 J Bangladesh Soc Physiol. 2009 June; 4(1): 20-23

scholarly journals Mobile Phone Dependence among Undergraduate Students of a Medical College of Eastern Nepal: A Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (224) ◽  
Author(s):  
Kriti Thapa ◽  
Sami Lama ◽  
Rita Pokharel ◽  
Rambha Sigdel ◽  
Surya Prasad Rimal
Keyword(s):  
Mobile Phone ◽  
Undergraduate Students ◽  
Mobile Phones ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Mobile Phone Addiction ◽  
Mobile Phone Usage ◽  
One Year

Introduction: Mobile phones are becoming increasingly indispensable in daily life of the studentswhich has resulted in mobile phone dependence. The objective of the study was to find the prevalenceof mobile phone dependence among undergraduate students of a medical college of Eastern Nepal. Methods: A descriptive cross-sectional study was conducted from October 2016 to March 2017on a total of 390 undergraduate students aged between 17 and 25 years using stratified samplingtechnique. Students using mobile phones for more than one year was included in the study. Studentswere requested to complete a pretested self-administered questionnaire which comprised theirsocio-demographic characteristics, pattern of mobile phone usage and mobile phone addiction indexdeveloped by Leung. Results: The prevalence of mobile phone dependence among the undergraduate students was foundto be 85 (21.8%). Mobile phone dependence was found to be related with time spend on mobile; callsper day, money spend on recharge per month and years of ownership of mobile phone. There wasno difference between males and females with regard to mobile phone dependence. Conclusions: The present study found that mobile phone dependence was common among theundergraduate medical students. These results suggest the need to develop educational programmeto educate the students to use mobile phone meaningfully.

scholarly journals Validity of Katex Test for Diagnosis of Visceral Leishmaniasis

2018 ◽  
Vol 4 (2) ◽  
pp. 45-47
Author(s):  
Ishrat Sharmin ◽  
AKM Quamruzzaman ◽  
Rezina Parveen ◽  
Rashida Akter Khanam ◽  
Md Abdullah Yusuf
Keyword(s):  
Bone Marrow ◽  
Urine Sample ◽  
Leishmania Donovani ◽  
Cross Sectional Study ◽  
Carbohydrate Antigen ◽  
Cross Sectional ◽  
Medical College ◽  
Kala Azar ◽  
Heat Stable ◽  
One Year

Background: Newly developed KAtex test can be used as a non invasive tool for diagnosis of Kala-azar.Objectives: The aim of the present study was to validate the KAtex method to diagnose VL.Methodology: This was a cross-sectional study carried out in the Department of Microbiology at Dhaka Medical College, Dhaka, Bangladesh in collaboration with the department of Parasitology at Institute of Epidemiology, Disease control and Research (IEDCR), Dhaka, Bangladesh for a period of one year. Clinically suspected Kala- azar (VL) cases of different age and sex attending IEDCR from different Kala-azar endemic areas of Bangladesh were selected for this study. Microscopy and culture was performed with Bone marrow (BM). KAtex was performed with urine sample. Urine samples taken from cases were pretreated to inactivate heat labile materials which might cause a false positive reaction. Antigen which is detected by KAtex is heat stable carbohydrate antigen. Latex sensitized with antibodies raised against Leishmania donovani antigen was mixed with the urine sample on a glass slide. No agglutination indicates absence of antigen in urine.Result: Cases were 130. Among 130 clinically suspected VL cases, 70 (53.85%) cases were BM positive and 60 (46.15%) cases were BM negative. All the 70 BM positive cases were positive by KAtex. Among 60 BM negative cases, 15 were positive by KAtex. The sensitivity of KAtex is 100% and specificity is 75%. Highest percentage (52.86%) of bone marrow positive cases were below 10 years of age group.Conclusion: In conclusion, KAtex test is a good diagnostic tool for the detection of VL.Bangladesh Journal of Infectious Diseases, December 2017;4(2):45-47

scholarly journals Comparison of Test Validity of Magnetic Resonance Imaging in the Diagnosis of Diffierent Grades of Astrocytoma

2019 ◽  
Vol 46 (2) ◽  
pp. 48-52
Author(s):  
Swati Munshi ◽  
Farid Ahmed ◽  
Bibekananda Halder ◽  
Abdullah Yousuf ◽  
Md Mahbubur Rahman ◽  
...  
Keyword(s):  
Test Validity ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Resonance Imaging ◽  
Cross Sectional ◽  
Medical College ◽  
Study Population ◽  
Grade Ii ◽  
One Year ◽  
Grade Iii

Accurate detection of astrocytomas is very difficult. The purpose of the present study was to evaluate the usefulness of MRI in detection of intracranial astrocytoma. This cross-sectional study was conducted at the Department of Radiology and Imaging with the collaboration of Department of Neurosurgery and Department of Pathology at Sir Salimullah Medical College (SSMC & MH), Dhaka from January 2013 to December 2013 for a period of one year. All the clinically suspected and CT scan diagnosed cases of intracranial astrocytoma patients of any age of both sexes were included as study population. All cases having no contraindication for MRI underwent MR examination. MR imaging was obtained with 0.5 Tesla machine (SIEMENS). The postoperative resected tissues were examined histopathological in the respective department. Then the collected reports were compared with findings of MRI. The sample size of the present study was 48 astrocytoma patients. The highest sensitivity was found in grade III astrocytoma (90.5%) followed by grade II (85.7%) grade IV (75.0%) and grade I (60.0%). The highest specificity was found in grade I astrocytoma (97.7%) followed by Grade III (96.3%), grade IV (92.5%) and grade II (91.5%). The highest accuracy was found in both grade I astrocytoma (93.7%) and grade III (93.7%) followed by grade II (92.5%) and grade IV (89.6%). In the conclusion, MRI is an effective tool for the diagnosis of astrocytoma. MRI has a high diagnostic validity for the detection of different grades of astrocytoma. Bangladesh Med J. 2017 May; 46 (2): 48-52

CLINICAL PROFILE OF PATIENTS WITH SINONASAL MASSES - A CROSS SECTIONAL STUDY

2021 ◽  
pp. 1-2
Author(s):  
Aiswarya Gopalakrishnan ◽  
Pramod Menon
Keyword(s):  
Clinical Symptoms ◽  
Cross Sectional Study ◽  
Clinical Profile ◽  
Government Medical College ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Clinical Presentations ◽  
One Year ◽  
Posterior Rhinoscopy

It is challenging to diagnose and distinguish sinonasal masses as they can have varying clinical presentations. This study was done to see if sinonasal masses can be detected by clinical symptoms, signs and examination itself without resorting to investigations. This cross sectional study was conducted in the department of Otolaryngology, Government Medical College Thrissur, Kerala for a period of one year from December 2017 to December 2018. Total 104 cases were studied. Most of the sinonasal masses were identied by doing proper anterior and posterior rhinoscopy which don’t require much expertise to master. This can be considered only as a screening because any intervention should be preceded by radiological investigations and biopsy for a denitive management.

scholarly journals Surgical Site Infection Incidence Following Hip Surgery: A Cross-Sectional Study

2021 ◽  
pp. 66-74
Author(s):  
Niaz Hussain Keerio ◽  
Ghazanfar Ali Shah ◽  
Tanveer Afzal ◽  
Aftab Alam Khanzada ◽  
Muhammad Rafique Joyo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hip Fracture ◽  
Surgical Site Infection ◽  
Cross Sectional Study ◽  
Site Infection ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Surgical Site Infection Incidence ◽  
One Year

Objective: To determine the incidence of surgical site infection among patients with hip fracture and undergo a surgical procedure for management. And to spotlight on the risk factors which may lead to surgical site infection among them. Also, to look for other complications following the surgery. Methods: This is a descriptive, correlational cross-sectional study design. The study was conducted at Orthopedic Department, Mohammad Medical College and Hospital Mirpurkhas, Pakistan for one-year duration from March 2019 to March 2020. All patients had hip fracture and received management at the department of orthopedic. All patients were adults and older than 20 years of age. Data was analyzed using SPSS program. Results: The study included 103 patients who had hip fractures. The most frequent age group was 40-50 years. Patients had a mix of modifiable and non-modifiable risk factors for developing surgical site infection. The incidence rate of surgical site infection in this study was 3.2%. It was correlated to having hypertension and diabetes as complications. Conclusion: This study aimed to spotlight on the SSI following hip surgeries and to look for complications and risk factors. We noticed that the SSI rate among the study populations is almost similar as the worldwide range. This is due to the agreed protocol for managing patients. However, there is a need for log-term follow up for our patient to discover the cases of delayed SSI.

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