scholarly journals Pattern of Nodal Metastasis in Laryngeal Carcinoma

2020 ◽  
Vol 23 (2) ◽  
pp. 109-114
Author(s):  
Md Hasan Zafar ◽  
Md Mozharul Islam ◽  
Md Manjur Rahim ◽  
Ahmmad Taous ◽  
Md Khalid Asad ◽  
...  

Aims: To find out the occurrence of lymph node metastasis, level of neck node involvement and the pattern of clinical presentation of patients suffering from laryngeal carcinoma. Methods: A cross-sectional study on 90 cases of laryngeal carcinoma was carried out in the inpatient department of Otolaryngology- Head and neck surgery of Dhaka Medical College Hospital, Dhaka during a period of two years. Smoking and chewing betel leaf and tobacco are the most important predisposing factors. Results: Most of the cases presented with more than one symptom. Change of voice was the commonest symptom. Cervical lymphadenopathy are significantly associated with supraglottic carcinoma. Level IV and level III is the commonest level of the lymph node involvement in laryngeal carcinoma. Bangladesh J Otorhinolaryngol; October 2017; 23(2): 109-114

2020 ◽  
Vol 25 (2) ◽  
pp. 102-107
Author(s):  
Md Momin Uddin ◽  
Samia Quadir ◽  
Sabiha Quadir ◽  
Kazi Shameemus Salam ◽  
Debabrota Roy ◽  
...  

Background: Head and neck cancers include cancers of the lips, mouth, nasal cavity, paranasal sinuses, pharynx and larynx. Most of these cancers are squamous cell carcinomas (SCCs). The presence of metastatic cervical lymphadenopathy is of particular importance as with every single nodal metastasis, survival of the patient is reduced by one half. Objective: To see the prevalence of metastatic neck node. Methods: The prospective cross-sectional clinical study was carried out in the Department of ENT and Head Neck Surgery, Combined Military Hospital, Dhaka during March’2018 to March, 2019. All 100 patients were included in this study and were treated at the Department of Otolaryngology of Combined Military Hospital, Dhaka. Results: Total 26 cases were found parotid among them 8(30.8%) in metastatic neck node and 18(69.2%) in without metastatic neck node. Total 10 cases were found paranasal sinuses among them 1(10.0%) in metastatic neck node and 9(90.0%) in without metastatic neck node. Which were statistically significant (p<0.05) between two groups. Conclusion: In this study observed that majority of metastatic neck node were found pyriform fossa, supraglottic larynx, base of tongue which were 68.2%, 68%, 77.8% respectively. In oral cavity and parotid site also found 48.1% and 30.8% metastatic neck node. Bangladesh J Otorhinolaryngol; October 2019; 25(2): 102-107


2020 ◽  
Vol 2020 (10) ◽  
Author(s):  
Yi Ying Law ◽  
Rhea Patel ◽  
Rebecca Yorke ◽  
Harold R Bailey ◽  
Jeffrey L Van Eps

Abstract Endometriosis is a clinical condition with a wide spectrum of severity, and a subset that includes intestinal involvement that may even mimic malignancy, making non-surgical diagnosis difficult. Cecal endometriosis is a rare finding among intestinal endometriosis. We report on 33-year-old woman with ileocecal endometriosis presenting as endoscopic prolapse of the ileocecal valve associated with a mass on cross-sectional imaging. The diagnosis was suggested intraoperatively by peritoneal endometrioma and obliteration of the appendix during laparoscopic right hemicolectomy. Pathological review demonstrated extensive submucosal, infiltrative endometriosis with mass effect and lymph node involvement. This case highlights the difficulty in preoperative diagnosis of intestinal endometriosis and the wide-ranging potential tissue effects in cases of infiltrative disease.


2015 ◽  
Vol 21 (1) ◽  
pp. 17-22
Author(s):  
Md Mazibur Rahman ◽  
Mohammad Idrish Ali ◽  
Md Momenul Haque ◽  
Md Harun Ar Rashid Talukder ◽  
Masroor Rahman ◽  
...  

Objectives: To find out the incidence, distribution, level and staging of cervical nodal metastasis.Methods: This is a retrospective study carried out in the Department of Otolaryngology Head and Neck Surgery, BSMMU and Dhaka Medical College Hospital, Dhaka, from January 2005 to December 2005. Total 60 cases were studied. The diagnosis was made by detailed history, clinical examination, investigation. Analyzed data presented by various tables, graphs and figures.Results: In this study primary lesion was identified in 88.33% cases and undetected cases were 11.7%, 81.13% were squamous lining and 18.87% non-squamous. Highest frequency of metastatic node was found with carcinoma larynx (36.66%). Male and age of 41-50 years was had highest incidence. About 43.33% had dysphagia, 38.33% had hoarseness of voice, 13.33% respiratory distress, 8.33% strider and 8.33% had referred otalgia. The disease was unilateral 81.67%, 63.33% multiple node involvement, highest involvement in level II & III and stage N2 larynx was commonest site of involvement.Bangladesh J Otorhinolaryngol; April 2015; 21(1): 17-22


2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 57-57
Author(s):  
Noriyuki Nishiwaki ◽  
Masanori Tokunaga ◽  
Kenichiro Furukawa ◽  
Keiichi Fujiya ◽  
Hayato Omori ◽  
...  

57 Background: Extra-nodal metastasis (ENM) is defined as a tumor nodule without lymph node structure, and distinguished from lymph node metastasis by histological findings. Despite the possible difference in metastatic mechanism, both are counted as metastasized lymph nodes according to the 3rd English edition of Japanese Classification of Gastric Carcinoma, and thus the prognostic value of ENM remains unclear. The aim of this study was to clarify the clinicopathogical characteristics and prognostic impact of ENM in gastric cancer patients with lymph node involvement. Methods: This study included 388 patients who underwent curative gastrectomy for primary gastric cancer between January 2009 and August 2013. A total of 2093 pathologically positive tumor nodules, including both metastatic lymph nodes and ENM, were examined. Clinicopathological characteristics and survival outcomes were compared between an ENM positive (ENMP) group (95 patients) and an ENM negative (ENMN) group (293 patients). In addition, multivariable analysis was performed to clarify the independent prognostic factors. Results: ENM was found in 269 of 2093 tumor nodules (12.9 percent). The incidence of ENM was significantly higher in patients with large tumor size, high pathological T stage (pT), high pathological N stage (pN) and in those with macroscopic infiltrative tumors, vascular and lymphatic invasion. Three-year relapse free survival was significantly worse in the ENMP group (56.5%) than in the ENMN group (82.4%, p < 0.001). Multivariable analysis revealed that ENM as well as age, pT and histological type was an independent prognostic factor. Conclusions: ENM is an independent prognostic factor in gastric cancer patients with lymph node involvement. A new N classification stratified by the presence of ENM might be considered.


2020 ◽  
Vol 22 (2) ◽  
pp. 66-70
Author(s):  
Mohammad Harun Or Rashid ◽  
Md Abdus Sattar ◽  
Abm Luthful Kabir ◽  
Md Anamul Haque ◽  
Dhiman Pramanik ◽  
...  

Objective: To determine the pattern of metastesis of squamous cell carcinoma in cervical lymph node. Methods: This was an observational cross sectional study which was carried out in the departments of Otolaryngology and Head-Neck surgery of Bangabondhu Sheikh Mujib Medical University and Dhaka Medical College Hospital during the period of July 2012 to March 2013. A Total 30 patients were selected according to selection criteria and level of involved lymph node and nodal staging was determined by careful clinical examination, biopsy of all suspicious site, CT scan, MRI, USG and X-ray. Results: In this study majority of patients were within 40-80 years and most of patients were male. Maximum lymph nodes were 3-6 cm in size.90% cases were unilateral.50% cases were involved in level-II and most of cases (46.68%) were in stage N2. Conclusion:Metastetic squamous cell carcinoma in cervical lymph node of occult primary common in elderly patient and most of were male and involved the lymph node level II. Bangladesh J Otorhinolaryngol; October 2016; 22(2): 66-70


1970 ◽  
Vol 11 (1) ◽  
pp. 25-27
Author(s):  
AH Kafi ◽  
HB Arif ◽  
AS Ruhul

Objective: A study was carried out to know the overall prevalence of various causes responsible for cervical lymphadenopathy of more than 3 weeks duration. FNAC has been evaluated as a diagnostic tool in our clinical set up. We aimed to present 120 cases which we treated in our center within last 4 years. Methods: A retrospective study has been carried out from August 2007 to August 2011 in the department of Otolaryngology and Head-Neck Surgery at CMH Rangpur, Apollo Hospitals Dhaka And Ibn Sina Medical College Hospital Dhaka. All patients presented with cervical lymphadenopathy of more than 3 weeks duration. FNAC has been done for all suspected cases. CT neck has been done in 4 cases for deep jugular nodes. 60 patients underwent lymph node biopsy as FNAC report was non-specific lymphadenitis. For three cases we have done frozen section biopsy. Preoperative workup with routine blood tests, Xray chest and tuberculin tests have been carried out for all cases. Results: Out of 120 FNAC of cervical lymphadenopathy - 60 were non-specific lymphadenitis, 34 were tuberculosis, 13 were metastatic (with 2 occult primary), 7 were lymphomas (Immunocytochemistry proved ) and 6 were abscess. All 60 non-specific lymphadenopathy cases (FNAC report) underwent lymph node biopsy.5 cases were consistent with tuberculosis , 1 was lymphoma and rest were reactive . For 3 cases frozen section biopsy have been done. One was consistent with granulomatous disease and two cases were diagnosed as lymphoid hyperplasia. Both the lymphoid hyperplasia cases have been diagnosed as Castleman's disease after histopathology report. Conclusion: The study concluded the fact that the non-specific infection is the most common cause of cervical lymphadenopathy followed by tuberculosis .Supplemented with routine laboratory investigations, FNAC give very important clue to the physicians that can be routinely used in patients with cervical lymphadenopathy. DOI: http://dx.doi.org/10.3329/bjms.v11i1.9818 BJMS 2012; 11(1): 25-27


2013 ◽  
Vol 4 (2) ◽  
pp. 47-49
Author(s):  
Ali Imam Ahsan ◽  
Kamrul Hasan Tarafder ◽  
Sheikh Hasanur Rahman ◽  
Nasimul Jamal ◽  
Syed Farhan Ali ◽  
...  

Background: Regional metastases to the cervical lymph node is common in laryngeal carcinoma and this is also the most important prognostic factor of the disease. Objective: The purpose of the present study was to see the frequency of cervical metastases related to the sites of laryngeal carcinoma and also to see the relation between primary site and level of metastatic node as well as the relation between T and N stage of the tumour. Methodology: This cross sectional study was done in the Department of Otolaryngology and Head-Neck Surgery at Bangabandhu Sheikh Mujib Medical University, Dhaka and Specialized ENT Hospital of SAHIC, Dhaka from April 2009 to March 2010. A total number of 50 patients who were histopathologically proven laryngeal carcinoma at any age with both sexes were included in this study. General physical examination and ENT examination was done thoroughly. Direct laryngoscopy was done under general anaesthesia to assess the site, size, and extension of the tumour as well as for staging and biopsy. Results: A total number of 60% laryngeal carcinoma patients presented with regional metastases to the cervical nodes. Highest cases among laryngeal carcinoma were supraglottic carcinoma (72.0%) which also showed the highest rate of lymph node metastases (72.2%). Most frequently involved levels of the neck were level II (56.7%) and level III (33.3%). It was also observed that the rate of regional metastases was increasing with the advancing T-stage of the disease. Conclusion: Regional metastases is a useful prognostic indicator of the laryngeal carcinoma. So, early detection of the disease has a great importance on the management of the disease. DOI: http://dx.doi.org/10.3329/jssmc.v4i2.14406 J Shaheed Suhrawardy Med Coll, 2012;4(2):47-49


2020 ◽  
Vol 22 (1) ◽  
pp. 43-46
Author(s):  
Mst Jesmen Nahar ◽  
Md Mahiuddin Matubber ◽  
Md Mahbubur Rahman ◽  
Md Mahbubur Rahman ◽  
Syed Muhammad Baqul Billah ◽  
...  

Background: Carcinoma stomach, a major killer cancer all over the world, is still presenting late in developing countries due to delay in early diagnosis, lack of awareness, infrastructure etc. Objectives: To establish the importance of preoperative evaluation on operability of carcinoma stomach. Methods: Sixty clinically and histopathologically diagnosed ca stomach cases who underwent surgery in department of Bangabandhu Sheikh Mujib Medical University, Dhaka, and Dhaka Medical College Hospital, Dhaka in 2011 were assessed with clinical picture, investigations, preoperative evaluation and peroperative findings were recorded. Z test for proportion was used to assess clinical decision predictability with a p value of :s;0.05 as significant. Results: Male (73.33%) predominant with 2.75:1 male:female ratio was observed. Mobility, fixity and abdominal lymphadenopathy were not well detected through clinical assessment (p=0.001) while ascites, metastasis and Shelf of Slummer were similar in both clinical and operative finding. The endoscopy of upper GIT finding gave a unique picture as the findings were almost same as were found during operation. USG detected a lesser proportion of the clinical condition compared to peroperative condition whereas CT performed better than the USG except for the lesion detection. Though Computed Tomography (CT) detected higher percentage of lesion, metastasis, ascites and lymph node involvement compared to ultrasonogram (USG), it was significantly higher only for lesion detection (p=0.002) and lymph node involvement (p=<0.001). In the similar manner USG assessment of lesion detection (p=<0.001) and lymph node involvement (p=0.003) was significantly low compared to operative finding. When we looked between CT and operative finding only lesion detection was significantly low (p=0.01) indicating CT to be most effective predictor of clinical picture for operative decision. Preoperative plan were mostly not in accordance with peroperative decision except for total gastrectomy. Conclusion: The study indicates weakness in clinical detection and pre-operative plan compared to per-operative finding. Hence combination of clinical feature and investigation tools especially endoscopy of upper GIT combined with CT is recommended to predict a better operative decision. Journal of Surgical Sciences (2018) Vol. 22 (1): 43-46


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