scholarly journals Serum Calcium Level in Patients with Pre Eclampsia : A Case Control Study

2021 ◽  
Vol 20 (1) ◽  
pp. 33-36
Author(s):  
Rajasree Bhowmick ◽  
Juthi Bhowmik ◽  
Shiuly Chowdhury ◽  
Ayesha Najma Nur ◽  
Firoza Begum
Keyword(s):  
Pregnant Women ◽  
Serum Calcium ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Case Control Study ◽  
Calcium Supplementation ◽  
Case Control ◽  
Control Group ◽  
Group Data ◽  
Control Study

Background: To compare serum calcium level in pre-eclamptic women and normal pregnant women. Materials and methods: It was a case-control study carried out in patient Department of Fetomaternal Medicine unit in the Department of Obstetrics & Gynaecology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. From September 2010 to February 2011. Total 60 cases, among them 30 comprising control group and 30 were cases. This was a non interventional case control study that was carried out on total 60 women with age range 18 to 38 years of them 30 healthy gravid women as control group and 30 pregnancy with pre eclampsia as case. Serum calcium level of the groups were measured, and compare between this two group. Data were analyzed by computer with the help of SPSS (Statistical Package for Social Sciences) win 13 software package. Results: Serum calcium in pre-eclamptic women was significantly low [7.88±0.75mg/dl vs 9.9267±0.58 mg/dl] than in normal pregnant women. Conclusion: Serum calcium may be used for earlier detection of preeclampsia. Further studies are required to investigate whether calcium supplementation can be used as a preventable measure for the development of preeclampsia. Chatt Maa Shi Hosp Med Coll J; Vol.20 (1); January 2021; Page 33-36

scholarly journals PRE-ECLAMPTIC AND NORMOTENSIVE PREGNANCIES

2016 ◽  
Vol 23 (11) ◽  
pp. 1358-1363
Author(s):  
Muhammad Akram ◽  
Muhammad Faisal Nadeem ◽  
Ashba Anwar ◽  
Fareen Anwar Memon ◽  
Muhammad Imtiaz Shafiq ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Serum Calcium ◽  
Maternal Morbidity ◽  
Serum Calcium Level ◽  
Case Control Study ◽  
Study Groups ◽  
Case Control ◽  
Normal Women ◽  
Study Setting ◽  
Control Study

Background: Pre-eclampsia along with its consequences is one of the primarydriver of maternal morbidity and horribleness. Despite the availability of magnificent literature,the onset of pre-eclampsia has yet not been fully understood. Objectives: To compare the serumcalcium level among pre-eclampsia and the normal women during pregnancy. Patients andMethods: Study Design: Hospital based case control study. Setting: Gynecology Departmentof Jinnah Hospital Lahore. Period: 1st July 2014 to 31 December 2014. The study groups consistof the 30 pre-eclamptic subjects and women with normal pregnancies. The serum calciumlevel of the subjects under this study was determined using standard colorimetric analyzer.Results: The results of our study determined that serum calcium level among the pre-eclampticand the normotensive pregnant women was statistically significantly lower as compared to thenormal pregnant women. Conclusion: The findings of current work are statistically significantto establish that concentration of serum calcium among pre-eclamptic subjects is lower than inthe normotensive women during pregnancy.

Pregnancy outcomes in adolescents: a case-control study in the West of Iran

2021 ◽  
Vol 17 ◽  
Author(s):  
Salman Khazaei ◽  
Saeid Bashirian ◽  
Akram Bathaei ◽  
Mohadese Sadri ◽  
Fateme Shirani ◽  
...  
Keyword(s):  
Prenatal Care ◽  
Pregnant Women ◽  
Adolescent Pregnancy ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Adult Women ◽  
The West ◽  
Adolescent Women ◽  
Control Study

Background: Adolescent pregnancy, pregnancy in women aged between 13-19 years, is considered a major health problem. Objective: This study was performed to determine the maternal, perinatal, and neonatal outcomes of adolescent pregnancies. Materials and Methods: The present hospital-based case-control study was performed on pregnant women who were referred to Fatemieh Hospital in Hamadan City for delivery. The case group was pregnant women whose gestational age was less than 19 years (adolescent pregnancy) and the control group included pregnant women whose gestational age was at 19-35 years (adult women pregnancy). Data were analyzed using Stata software version 14. The significant level was considered less than 0.05. Results: The unwanted pregnancy was significantly higher in adolescent women (45% vs. 28.5%, P=0.002). 18% of adolescent women had the experience of spouse violence compared to 4.25% in the control group (P<0.001). Accessing prenatal care and supplements were significantly higher in adult women (P<0.05). The adult mothers had significantly higher cesarean section delivery compared adolescent group (54.91% vs. 33%, P<0.001). Also, there was a significant association between postpartum hemorrhages and the study group (22% in cases compared to 13.75% in the control group, P=0.04). The Apgar score 1 minute was significantly higher in adult mothers (8.05±2.08 vs. 7.39±2.05, P<0.001). Conclusion: In conclusion, adolescent mothers in the west of Iran had a higher risk of inadequate prenatal care, low Apgar score and postpartum hemorrhage. Therefore, society should focus on public health policies that can improve the adequacy of prenatal care among adolescents.

scholarly journals Interaction between serum FGF-23 and PTH in renal phosphate excretion, a case-control study in hypoparathyroid patients

2019 ◽  
Author(s):  
Forough Saki ◽  
Seyed Reza Kassaee ◽  
Azita Salehifar Salehifar ◽  
gholamhossein Ranjbar omrani
Keyword(s):  
Parathyroid Hormone ◽  
Serum Calcium ◽  
Case Control Study ◽  
Fractional Excretion ◽  
Case Control ◽  
Control Group ◽  
Phosphate Excretion ◽  
Significant Difference ◽  
Fgf 23 ◽  
Control Study

Abstract Background:phosphate homeostasis is mediated through complex counter regulatory feed-back balance between parathyroid hormone, FGF-23 and 1,25(OH)2D. Both parathyroid hormone and FGF-23 regulate proximal tubular phosphate excretion through signaling on sodium- phosphate cotransporters II a and II c . However, the interaction between these hormones on phosphate excretion is not clearly understood. We performed the present study to evaluate whether the existence of sufficient parathyroid hormone is necessary for full phosphaturic function of FGF-23 or not. Methods:In this case-control study, 19 patients with hypoparathyroidism and their age- and gender-matched normal population were enrolled. Serum calcium, phosphate, alkaline phosphatase,parathyroid hormone, FGF-23, 25(OH)D, 1,25(OH)2D and Fractional excretion of phosphorous were assessed and compared between the two groups, using SPSS software. Results:The mean serum calcium and parathyroid hormone level was significantly lower in hypoparathyroid patients in comparison with the control group(P<0.001 and P<0.001, respectively). We found high serum level of phosphate and FGF-23 in hypoparathyroid patients compared to the control group (P<0.001 and P<0.001,respectively). However, there was no significant difference in Fractional excretion of phosphorous or 1,25OH2D level between the two groups. There was a positive correlation between serum FGF-23 and Fractional excretion of phosphorous just in the normal individuals (P <0.001, r = 0.79). Conclusions:Although the FGF-23 is a main regulator of urinary phosphate excretion but the existence of sufficient parathyroid hormone is necessary for the full phosphaturic effect of FGF-23.

scholarly journals Mode of Delivery in Drug-Dependent Pregnant Women: A Case Control Study

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Ana Raquel Neves ◽  
Fabiane Neves ◽  
Isabel Santos Silva ◽  
Maria do Céu Almeida ◽  
Pitorra Monteiro
Keyword(s):  
Pregnant Women ◽  
Vaginal Delivery ◽  
Case Control Study ◽  
Mode Of Delivery ◽  
Case Control ◽  
Control Group ◽  
Maternal Characteristics ◽  
Drug Dependent ◽  
Route Of Delivery ◽  
Control Study

Objective. To determine the contribution of drug use during pregnancy to the route of delivery.Methods. A case-control study was conducted at a hospital in Coimbra, Portugal, between 2001 and 2014. Drug-dependent pregnant women (n=236) were compared with a control group of low risk women (n=228) in terms of maternal characteristics, obstetric history, pregnancy complications, and labor details. Factors that influenced the mode of delivery were determined. Statistical analysis was performed with SPSS v. 23.0 (IBM Corp.).pvalues < 0.05 were considered statistically significant.Results. Drug-dependent women presented a lower rate of cesarean delivery (18.2 versus 28.9%,p=0.006). After adjusting for the factors that were significantly related to the mode of delivery, drug dependency influenced the rate of cesarean section (β=0.567; 95% CI = 0.328–0.980). Within the drug-dependent group, the mode of delivery was significantly related to previous cesarean or vaginal delivery (p=0.008andp<0.001, resp.) and fetal presentation (p<0.001), but not with the type of drug, route of administration, or substitution maintenance therapy.Conclusions. The drug-dependent group presented a significantly higher rate of vaginal delivery. However, this was not associated with the behavioral factors analyzed. We hypothesize that other social and psychological factors might explain this difference.

scholarly journals Safety and Efficacy of Ferric Carboxymaltose in Anemic Pregnant Women: A Retrospective Case Control Study

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Anouk Pels ◽  
Wessel Ganzevoort
Keyword(s):  
Pregnant Women ◽  
Pregnancy Outcomes ◽  
Case Control Study ◽  
Case Control ◽  
Ferric Carboxymaltose ◽  
Control Group ◽  
Efficient Treatment ◽  
Safety And Efficacy ◽  
Anemia During Pregnancy ◽  
Control Study

Background. Anemia during pregnancy is commonly caused by iron deficiency and can have severe consequences for both the mother and the developing fetus. The aim of this retrospective study was to assess the safety and efficacy of intravenous ferric carboxymaltose (FCM) in pregnant women.Methods. All women treated with FCM for anemia during pregnancy between 2010 and 2012 at our institution were included. A matched control group was selected, including women who either were nonanemic or had anemia but were not considered for intravenous iron. Main outcome measures were maternal safety and pregnancy outcomes.Results. The study included 128 patients (FCM: 64; control: 64). Median FCM dose was 1000 mg and median gestational age at the time of first treatment was 34 weeks and 6 days. Median Hb increased from 8.4 g/dL (interquartile range 7.7; 8.9 g/dL) at the first FCM administration to 10.7 g/dL (9.8; 11.5 g/dL;n=46with available Hb at delivery) at the time of delivery, achieving levels similar to those in the control group (10.8 g/dL [9.8; 11.8 g/dL;n=48]). No treatment-related adverse events were reported and no statistically significant differences in pregnancy outcomes were observed between groups.Conclusions. Within the limitations of this case control study, FCM was a safe and efficient treatment of anemia during pregnancy.

Assessment of fetal Doppler parameters in pregnant women with COVID-19 infection: a prospective case-control study

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Sule Goncu Ayhan ◽  
Atakan Tanacan ◽  
Aysegul Atalay ◽  
Selcan Sinaci ◽  
Eda Ozden Tokalioglu ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Case Control Study ◽  
Case Control ◽  
Ductus Venosus ◽  
Control Group ◽  
City Hospital ◽  
Fetal Doppler ◽  
Control Study ◽  
Prospective Case Control Study ◽  
Demographic Features

Abstract Objectives To investigate the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on fetal Doppler parameters. Methods This was a prospective case-control study conducted in Ankara City Hospital with confirmed SARS-CoV-2 infected pregnants between August 1, 2020 and October 1, 2020. There were 54 COVID-19 confirmed pregnant women and 97 age-matched pregnant women as a control group between 28 and 39 weeks. Infection was confirmed based on positive real-time polymerase-chain reaction results. Demographic features, uterine artery (right, left), umblical artery, middle cerebral artery, ductus venosus, cerebro-placental ratio, and cerebral-placental-uterine ratio Doppler parameters were investigated in both groups. Results Two groups were similar in terms of demographic features and no difference was found for fetal Doppler parameters. Conclusions COVID-19 seems to have no adverse effect on fetoplacental circulation in mild and moderate patients during the acute phase of the infection.

scholarly journals Impact of SARS-CoV-2 Infection During Pregnancy on Infant Neurobehavioral Development: A Case-Control Study

2021 ◽  
Vol 9 ◽  
Author(s):  
Yao Cheng ◽  
Haoyue Teng ◽  
Yue Xiao ◽  
Mengxin Yao ◽  
Jieyun Yin ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Case Control Study ◽  
Statistical Significance ◽  
Case Control ◽  
Control Group ◽  
Neurobehavioral Development ◽  
Ages And Stages Questionnaires ◽  
Group 5 ◽  
Larger Sample ◽  
Control Study

Background: Previous studies on the pneumonia outbreak caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have focused on the general population and pregnant women, while little is known about the effects of SARS-CoV-2 on retardation during and after pregnancy. The purpose of this study was to evaluate the potential influence of SARS-CoV-2 on infant neurobehavioral development.Methods: A case-control study was conducted in Wuhan Maternal and Child Health Hospital, China. Nine pregnant women with SARS-CoV-2 infection and 9 controls matched by maternal age, parity, and status of chronic disease were included. Infantile neurobehavioral development was assessed through the Ages and Stages Questionnaires Edition 3 (ASQ-3).Results: The majority of pregnant women with SARS-CoV-2 experienced cesarean section (7 of 9), which was higher than the control group (5 of 9). The throat swabs of all newborn were negative. We found that compared with the control group, neonates of mothers with SARS-CoV-2 infection during pregnancy had lower scores in communication, gross movement, fine movement, problem solving, and personal-social domains; but only fine movement domain yielded statistical significance (P = 0.031).Conclusion: Infection with SARS-CoV-2 during pregnancy may have a certain impact on infant neurobehavioral development. Further studies with larger sample size are warranted for validation.

scholarly journals A cross sectional study to evaluate serum calcium levels among pregnant women and it's association with preeclampsia and delivery outcomes at tertiary care Hospital Bikaner, Rajasthan

2021 ◽  
Vol 10 (5) ◽  
pp. 2026
Author(s):  
Laxmi Poonia ◽  
Swati Kochar ◽  
Shweta Chaudhary ◽  
Priyanka Gaur ◽  
Kirti Solanki
Keyword(s):  
Pregnant Women ◽  
Serum Calcium ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Control Group ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional

Background: Hypertensive disorders of pregnancy, including preeclampsia complicates about 10% of pregnancies worldwide. Preeclampsia is one of the major cause of maternal and perinatal morbidity and mortality worldwide. According to the National Health Portal of India, the incidence of preeclampsia is reported to be about 8-10% among pregnant women. The present study was aimed to compare mean serum calcium levels in preeclamptic and normotensive pregnant women at third trimester of gestation and assess relationship between maternal serum calcium levels, severity of disease and overall maternal and perinatal outcome.Methods: This was a cross sectional study conducted on 200 females divided into two groups (i.e. Study and Control Group) from 1st November 2019 to 31st October 2020. Informed consent was obtained for subjecting. Detailed history and clinical examination were performed. Serum calcium level was measured in both groups by spectrophotometric method.Results: Mean serum calcium level in study group (preeclamptic) was 7.84+0.74mg/dl while in control group (normotensive) mean serum calcium level was 9.68+0.97mg/dl. Serum calcium level was significantly lower in preeclamptic women than normotensive pregnant women (p<0.001).Serum calcium showed significant negative correlation with systolic and diastolic blood pressure.Conclusions: This study concludes that hypocalcaemia may have a role in aetiology of preeclampsia and adverse maternal and perinatal outcome. Thus intake of calcium supplements may help in reduction of incidence of preeclampsia especially in a population of a developing country. 

scholarly journals Interaction between serum FGF-23 and PTH in renal phosphate excretion, a case-control study in hypoparathyroid patients

2019 ◽  
Author(s):  
Forough Saki ◽  
Seyed Reza Kassaee ◽  
Azita Salehifar Salehifar ◽  
gholamhossein Ranjbar omrani
Keyword(s):  
Parathyroid Hormone ◽  
Serum Calcium ◽  
Case Control Study ◽  
Fractional Excretion ◽  
Case Control ◽  
Control Group ◽  
Phosphate Excretion ◽  
Significant Difference ◽  
Fgf 23 ◽  
Control Study

Abstract Background phosphate homeostasis is mediated through complex counter regulatory feed-back balance between parathyroid hormone, FGF-23 and 1,25(OH)2D. Both parathyroid hormone and FGF-23 regulate proximal tubular phosphate excretion through signaling on sodium- phosphate cotransporters IIa and IIc. However, the interaction between these hormones on phosphate excretion is not clearly understood. We performed the present study to evaluate whether the existence of sufficient parathyroid hormone is necessary for full phosphaturic function of FGF-23 or not. Methods In this case-control study, 19 patients with hypoparathyroidism and their age- and gender-matched normal population were enrolled. Serum calcium, phosphate, alkaline phosphatase,parathyroid hormone, FGF-23, 25(OH)D, 1,25(OH)2D and Fractional excretion of phosphorous were assessed and compared between the two groups, using SPSS software. Results The mean serum calcium and parathyroid hormone level was significantly lower in hypoparathyroid patients in comparison with the control group(P<0.001 and P<0.001, respectively). We found high serum level of phosphate and FGF-23 in hypoparathyroid patients compared to the control group (P<0.001 and P<0.001,respectively). However, there was no significant difference in Fractional excretion of phosphorous or 1,25OH2D level between the two groups. There was a positive correlation between serum FGF-23 and Fractional excretion of phosphorous just in the normal control population(P <0.001, r = 0.79). Conclusions Although the FGF-23 is a main regulator of urinary phosphate excretion but the existence of sufficient parathyroid hormone is necessary for the full phosphaturic effect of FGF-23.

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