scholarly journals Effect of Losartan and Atenolol on Lung Function Status in Newly Diagnosed Essential Hypertensive Patients

2015 ◽  
Vol 10 (2) ◽  
pp. 85-89
Author(s):  
Mst Nasrin Nahar ◽  
Shelina Begum ◽  
Sultana Ferdousi ◽  
Sharmeen Sultana ◽  
Zinia Parveen
Keyword(s):  
Blood Pressure ◽  
Lung Function ◽  
Antihypertensive Drugs ◽  
T Test ◽  
Control Group ◽  
Angiotensin Ii Receptor Blocker ◽  
Newly Diagnosed ◽  
Hypertensive Patients ◽  
50Mg Daily ◽  
Normotensive Subjects

Introduction: Essential hypertension is associated with altered pulmonary function. Antihypertensive medication and lung function are also associated. Losartan (angiotensin II receptor blocker) and atenolol (beta blocker) are commonly used antihypertensive drugs.Objective: To evaluate the effects of antihypertensive drugs on lung function status in patients with essential hypertension.Methods: This prospective observational study was carried out in the Department of Physiology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, from July 2012 to June 2013 on 100 newly diagnosed essential hypertensive patients who had not received any antihypertensive medications. They were selected from the Out Patient Department (OPD) of Cardiology unit, BSMMU, Dhaka. The study sbujects of age between 30-55 were allocated in group B. Based on prescribed treatment, these study subjects were divided into two groups - B1 and B2. B1 included 50 patients who received losartan 50mg daily and B2 included 50 patients who received atenolol 50mg daily. Again basing on duration of treatment group B1 was divided into B1a (newly diagnosed hypertensive patients before treatment), B1b (after 3 months of medication with losartan) and B1c (after 6 months medication with losartan). Similarly group B2 was divided into B2a, B2b, and B2c. For assessing lung function status, FVC, FEV1 and PEFR were measured with acomputer based Spirometer. Age, sex and BMI matched 50 apparently healthy normotensive subjects were also studied as control (group A). Data were compared among subjects of different groups. For statistical analysis independent sample ‘t’ test and paired sample ‘t’ test were performed.Results: Mean systolic blood pressure and diastolic blood pressure were significantly higher and mean FVC, FEV1 and PEFR were significantly lower in newly diagnosed hypertensive patients in comparison with that of healthy normotensive subjects. Mean FVC and FEV1 were found significantly higher in the group taking losartan for 6 months when compared to newly diagnosed hypertensive patients but lower than those of controls. In addition, mean FVC and FEV1 were found significantly lower in the group taking atenolol for 6 months when compared to newly diagnosed hypertensive patients and those of controls.Conclusion: Reduced lung function occurs in newly diagnosed essential hypertensive patients which improves by treatment with losartan but decreases after treatment with atenolol.Journal of Armed Forces Medical College Bangladesh Vol.10(2) 2014

scholarly journals Effect of Losartan and Amlodipine on Lung Function Status in Hypertensive Patients: A Randomized Control Trial

2020 ◽  
Vol 15 (1) ◽  
pp. 42-44
Author(s):  
Mst Nasrin Nahar ◽  
Shelina Begum ◽  
Sultana Ferdousi ◽  
Tamanna Habib
Keyword(s):  
Essential Hypertension ◽  
Lung Function ◽  
Antihypertensive Medication ◽  
Antihypertensive Drugs ◽  
Armed Forces ◽  
Control Group ◽  
Angiotensin Ii Receptor Blocker ◽  
Newly Diagnosed ◽  
Angiotensin Ii Receptor ◽  
Hypertensive Patients

Introduction: Essential hypertension is associated with altered pulmonary function. Antihypertensive medication and lung function are also associated. Losartan (angiotensin II receptor blocker) and amlodipine (calcium channel blocker) are commonly used antihypertensive drugs. Objectives: To evaluate the effects of antihypertensive drugs on lung function status in patients with essential hypertension. Materials and Methods: This prospective observational study was carried out in the Department of Physiology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, from July 2012 to June 2013 on 100 newly diagnosed hypertensive patients without any antihypertensive medication (group B, age 30-55 years). They were selected from the Out Patient Department (OPD) of Cardiology, BSMMU, Dhaka. Age, sex and BMI matched 50 apparently healthy normotensive subjects were also studied as control (group A). Based on treatment, these study subjects were divided into two groups (B1 and B2). Group B1 included 50 patients received losartan 50 mg daily and B2 included 50 patients received amlodipine 5 mg daily. They were observed once before the treatment (B1a and B2a), after 3 months of medication (B1b and B2b) and after 6 months of medication (B1c and B2c). For assessing lung function status, Forced Vital Capacity (FVC), Forced Expiratory Volume in 1st second (FEV1) and Peak Expiratory Flow Rate (PEFR) were measured with a RMS computer based Spirometer. Results: Mean FVC, FEV1 and PEFR were significantly lower in newly diagnosed hypertensive patients in comparison with that of healthy normotensive. Mean FVC, FEV1 and PEFR were found significantly higher in the group taking losartan and amlodipine for 6 months when compared to newly diagnosed but lower than those of controls. Conclusion: Reduced lung function occurs in newly diagnosed hypertensive patients which was improved by treatment with losartan and amlodipine. Journal of Armed Forces Medical College Bangladesh Vol.15 (1) 2019: 42-44

scholarly journals Variations of Lung Function Status in Hypertension and Antihypertensive Medication

2016 ◽  
Vol 12 (1) ◽  
pp. 28-32
Author(s):  
Mst Nasrin Nahar ◽  
Shelina Begum ◽  
Sultana Ferdousi ◽  
Sharmeen Sultana ◽  
Zinia Parveen ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Lung Function ◽  
Antihypertensive Medication ◽  
Antihypertensive Drugs ◽  
Armed Forces ◽  
Forced Expiratory Volume ◽  
Control Group ◽  
Newly Diagnosed ◽  
Hypertensive Patients ◽  
Normotensive Subjects

Introduction: Essential hypertension is associated with altered pulmonary function. Antihypertensive medication and lung function are also associated. Amlodipine (calcium channel blocker) and Atenolol (beta blocker) are commonly used antihypertensive drugs. Objective: To evaluate the effects of antihypertensive drugs on lung function status in patients with essential hypertension. Materials and Methods: This prospective observational study was carried out in the Department of Physiology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka, from July 2012 to June 2013 on 100 newly diagnosed essential hypertensive patients. Based on prescribed treatment, these study subjects were divided into two groups - B1 and B2. B1 included 50 patients who received amlodipine 5mg daily and B2 included 50 patients who received atenolol 50mg daily. Lung function tests were done in both B1 and B2 groups before taking medication, after 3 months of medication and after 6 months of medication. For assessing lung function status, Forced Vital Capacity (FVC), Forced Expiratory Volume in 1st second (FEV1) and Peak Expiratory Flow Rate (PEFR) were measured with a computer based Spirometer. Age, sex and BMI matched 50 apparently healthy normotensive subjects were also studied as control (group A). Data were compared among subjects of different groups. For statistical analysis independent sample‘t’ test and paired sample‘t’ test were performed. Results: Mean FVC, FEV1 and PEFR were significantly lower in newly diagnosed hypertensive patients in comparison with that of healthy normotensive subjects. Mean FVC, FEV1 and PEFR were found significantly higher in the group taking amlodipine for 6 months when compared to newly diagnosed hypertensive patients but lower than those of controls. In addition mean FVC and FEV1 were found significantly lower in the group taking atenolol for 6 months when compared to newly diagnosed hypertensive patients and those of controls. Conclusion: Reduced lung function occurs in newly diagnosed essential hypertensive patients which improve by treatment with amlodipine but decreases after treatment with atenolol. Journal of Armed Forces Medical College Bangladesh Vol.12(1) 2016: 28-32

scholarly journals Effect of Losartan and Atenolol on heart rate variability in newly diagnosed essential hypertensive patient

2016 ◽  
Vol 6 (2) ◽  
pp. 161
Author(s):  
Shamima Sultana ◽  
Shelina Begum ◽  
Sultana Ferdousi
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Essential Hypertension ◽  
Antihypertensive Drugs ◽  
Control Group ◽  
Newly Diagnosed ◽  
Hypertensive Patients ◽  
Group B ◽  
Mean Heart Rate

<p><strong>Background:</strong> Essential hypertension is associated with altered autonomic function. Essential hypertension is treated with drugs which modify the sympatho-parasympathetic balance. Losartan (angioteosin II receptor blocker) and atenolol (beta blocker) is commonly used antihypertensive drugs.</p><p><strong>Objective:</strong> To evaluate the effect of antihypertensive drugs on heart rate variability (HRV) in patients with essential hypertension.</p><p><strong>Methods:</strong> This prospective observational study was carried out in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka from July 2012 to June 2013 on 120 newly diagnosed hypertensive patients without any medication (group B, age 30-55 years). They were selected from the Out Patients Department (OPD) of cardiology, BSMMU, Dhaka. Age, sex and BMI matched 60 apparently healthy norrnotensive subjects were also studied as control (group A). Based on treatment, these study subjects were divided into two groups (BI and B2). Group B1<sub>a</sub> included 60 patients received Josartan 50 mg daily and B<sub>2a</sub> included 60 patients received atenolol 50mg daily. They were observed once before the treatment (B<sub>1a</sub> &amp; B<sub>2a</sub>), after 3 months medication (B<sub>1b</sub> &amp; B<sub>2b</sub>) and after 6 months medication (B<sub>1c</sub> &amp; B<sub>2c</sub>). For assessing HRV, Mean heart rate, Mean R-R interval, Max/Min R-R interval, SDNN, RMSSD were recorded by a polyrite. Data were compared among before treatment, after 3 months treatment and after 6 months treatment. For statistical analysis ANOVA, independent sample't' test and paired sample 't' test were performed. <strong></strong></p><p><strong>Results:</strong> Mean resting pulse rate, mean heart rate, systolic blood pressure, diastolic blood pressure were significantly higher and mean R-R interval, Max/Min R-R interval, SDNN, RMSSD were significantly lower in newly diagnosed hypertensive patients in comparison with that of healthy normoten­sive subjects and after treatment. Jn both groups SDNN, RMS SD, mean R-R interval were found significantly higher after 6 months of treatment compared to their values after 3 months treatment. Again these values were found close to the values in normotensive subjects. In addition, mean heart rate was found significantly lower in atenolol treated patients than those of controls. Again in atenolol group these values were found significanLly higher than the corresponding values in losartan treated patients after 6 months treatment. <strong></strong></p><p><strong>Conclusion:</strong> Reduced cardiac vagal tone occurs in newly diagnosed hypertensive patients which is improved by both losartan and atenolol and in particular atenolol was found more effective.</p>

scholarly journals Pengaruh Jus Apel Terhadap Penurunan Tekanan Darah pada Lansia Hipertensi di Puskesmas Muara Kaman

2018 ◽  
Vol 5 (2) ◽  
pp. 121-129
Author(s):  
Siti Khoiroh
Keyword(s):  
Blood Pressure ◽  
Community Health ◽  
Apple Juice ◽  
Antihypertensive Drugs ◽  
Intervention Group ◽  
T Test ◽  
Mean Difference ◽  
Control Group ◽  
P Value ◽  
The Mean

Background : Hypertension is a condition of high blood pressure in the arteries that lasted continuously for the long term. Hypertension can be overcome in two ways: pharmacology and non-pharmacology. Pharmacology treatment usually use medicine while one of the ways for non-pharmacology treatment is to consumes apple juice.Research Objective : The aim of this research is to know the effect of apple juice on blood pressure decrease in elderly people with hypertension at Muara Kaman Community Health Center.Methods : The design of this research used quasi experimental design (quasi experiment) with pretest posttest control group design. The sample of the research was hypertensive respondents at Muara Kaman Community Health Center as many as 30 respondents were divided into 2 groups, 15 intervention groups and 15 control groups. The sampling technique used purposive sampling. The research instruments were stethoscope and sphygmomanometer, data analysis using t test dependent and t test independent.Results : There were a significant influence between pretest and posttest of apple juice in the intervention group (P value = 0,000; P <0.005). The mean difference in systolic blood pressure in the intervention group and the control group also had significant differences (P value = 0.002; P <0.05), where as the mean difference in diastolic blood pressure in the intervention group and the control group also had significant differences (P value = 0,039; P <0,05).The Conclusions : The results of this research showed that consumes apple juice gives an effect on the blood pressure of hypertensive patients by consumes regularly.The Suggestions : Nurses and the public can use apple juice as one of the ways to handling to hypertension sufferers besides antihypertensive drugs.

scholarly journals PENGARUH PEMBERIAN JUS CAMPURAN BELIMBING (Averhoa carambola linn) DAN MENTIMUN (Cucumis sativus linn) TERHADAP TEKANAN DARAH PASIEN HIPERTENSI RAWAT JALAN DI RUMAH SAKIT UMUM DAERAH KOTA MATARAM

2019 ◽  
Vol 4 (1) ◽  
pp. 40
Author(s):  
Devi Rahma ◽  
Suhaema Suhaema ◽  
Fifi Luthfiyah ◽  
Made Darawati
Keyword(s):  
Blood Pressure ◽  
Treatment Group ◽  
Antihypertensive Drugs ◽  
Vegetable Consumption ◽  
Research Result ◽  
T Test ◽  
Control Group ◽  
High Potassium ◽  
Control Group Design ◽  
Average Blood Pressure

Background. Hypertension can be a risk factor for stroke, coronary heart disease, heart failure and kidney failure and is known as the thesilent killer. The prevalence of hypertension in West Nusa Tenggara Province is 24.3% (Riskesdas, 2013). Medical Record Data of Mataram City Public Hospital, hypertension became the first of the top 10 outpatient diseases in 2015. The only treatment for non-pharmacological hypertension was by increasing fruit and vegetable consumption due to high potassium content. Research Methods. The type of this research is experimentation with Randomized Control Trial (RCT) design with Pretest-Posttest with Control Group design. The number of subjects is 20 people obtained from the formula Lemeshow (1997). Both groups continued to take antihypertensive drugs, but the treatment group was given 250 ml of starfruit juice and cucumber juice for 7 days. The statistical analysis used was the paired t-test and independent t-test. Research Result. The average blood pressure before the study in the treatment group was 150/91 mmHg, in the control group it was 142/83 mmHg. The average blood pressure after the study for the treatment group was 132/81 mmHg, while the control group was 144/81 mmHg. There was a decrease in blood pressure in the treatment group after the intervention was 18 mmHg for systolic (p = 0.000) and 10 mmHg for diastolic (p = 0.004), but there was no decrease in blood pressure both systolic and diastolic in the control group. Conclusion. Giving a mixture of star fruit and cucumber juice affects the decrease in systolic and diastolic blood pressure.

scholarly journals Assessment of effectiveness of an interventional package on treatment adherence of hypertensive patients: a randomized control trial

2021 ◽  
Vol 8 (6) ◽  
pp. 2862
Author(s):  
Kmendalin Nongspung ◽  
Kavita Narang ◽  
J. S. Thakur
Keyword(s):  
Blood Pressure ◽  
Treatment Adherence ◽  
Randomized Control Trial ◽  
T Test ◽  
Control Group ◽  
Sampling Frame ◽  
Strict Adherence ◽  
Hypertensive Patients ◽  
Randomized Control ◽  
Experimental Group

Background: Hypertension is the most common non-communicable diseases. Strict adherence to prescribed antihypertensive treatments is the key to blood pressure control. The present study was conducted with the objective to develop, implement and assess an interventional package on treatment adherence for hypertensive patients.Methods: A clustered randomized control trial of 3 months conducted in two community sites of Chandigarh. The two sites were first randomized by lottery method as experimental and control sites. Total of 250 subjects (n=125 on each sites) were selected by a systematic random sampling technique (every fourth) from the sampling frame. Diagnosed hypertensive patients taking treatment were included in the study and females with pregnancy induced hypertension were excluded. Participants were interviewed as per Interview schedule. Data was collected from July to November 2018. Interventional package was in the form of booklet and flash card, delivered as one to one teachings. Total of 5 face to face follow ups were done to the experimental group. Control group received routine care. Final evaluation was done at 3rd month in both the groups to assess the effectiveness of an interventional package on treatment adherence. Data analysis and interpretation was done by using chi square, paired t test, unpaired t- test, Mc Nemar test were applied to determine the level of significance at p<0.05.Results: The proportion of subjects who were adhered to the treatment has increased from 16% to 68% in the experimental group at third month of follow up. The mean change in systolic blood pressure and diastolic blood pressure were 26.29±12.81 mmHg and 7.74±8.95 mmHg respectively in the experimental group as compared to the control group (p<0.05).Conclusions: The interventional package on treatment adherence among hypertensive patients was effective in improving the treatment adherence.

scholarly journals The Effect of Tiwari Onion (Eleutherine americana Merr) Tablet on Blood Pressure Stability in Diagnosed Hypertension Patients

2021 ◽  
Vol 9 (A) ◽  
pp. 556-561
Author(s):  
Widya Warastuti
Keyword(s):  
Blood Pressure ◽  
Pharmacological Therapy ◽  
T Test ◽  
Control Group ◽  
Elderly Age ◽  
Control Group Design ◽  
Pharmacological Management ◽  
Hypertensive Patients ◽  
Significant Difference ◽  
Eleutherine Americana

BACKGROUND: Non-pharmacological management is carried out by adjusting the lifestyle and non-pharmacological therapy for hypertension sufferers. They use herbal therapy, which is believed to have low side effects, easy, and inexpensive, such as Eleutherine americana Merr Tea. AIM: This study aimed to analyze Effect of E. americana Merr Tablet on blood pressure in hypertensive patients to be used as supportive therapy to reduce and stabilize blood pressure. METHODS: This study used a quasi-experimental research design pre-post-test with a control group design, involving 30 respondents. Data collection was carried out for 1 month. Then blood pressure observations were carried out every 1 week for a month after giving E. americana tablets. The sampling technique was purposive sampling method. The data analysis used was the Independent Sample T-Test with a significance level of p < 0.05. RESULTS: The majority of respondents according to age were in the final elderly age range; 15 people (50%) were 56–65 years old. Most of the respondents involved were female, about 18 people (60%). The respondents’ hypertension category included hypertension Grade 1 (57%) and hypertension Grade II (43%). The independent sample t-test obtained p = systole was 0.029 and diastole was 0.000 (p < 0.005). It showed a significant difference in blood pressure before and after being given E. americana tablets in hypertensive patients. CONCLUSION: Significant decrease in systolic and diastolic blood pressure in patients with suspected hypertension who obtained E. americana tablets.

The Correlation of Anxiety, Dyslipidemia and Oxidative stress in Prehypertensive and Hypertensive patients

2020 ◽  
Vol 11 (2) ◽  
pp. 2614-2619
Author(s):  
Elsa Mathew ◽  
Mukkadan J. K.
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Trait Anxiety ◽  
Normal Blood ◽  
Control Group ◽  
National Committee ◽  
Normal Blood Pressure ◽  
Hypertensive Patients ◽  
Normotensive Subjects ◽  
And Oxidative Stress

Studies have evaluated that high blood pressure kills nine million people annually Persistent. Psychological factors can be considered as a primary threat to the increase of hypertension. It may lead to cardiovascular disease, stroke and kidney disease. The current work was conducted to analyze the disparity of anxiety, dyslipidemia and oxidative stress in pre-hypertensive and hypertensive subjects. This was a cross-sectional study conducted among 180 subjects. Based on the Joint National Committee 8 Criteria, participants were divided into hypertensive patients (n₌60) and pre-hypertensive patients (n₌63). Fifty-seven healthy subjects with normal blood pressure were served as the control group. Anthropometric measurements and blood pressure were measured using the standard procedure. The biochemical parameters for measuring oxidative stress, blood glucose levels, and lipid profile were estimated. Anxiety level was assessed with the State-trait anxiety inventory (STAI) questionnaire. It is observed that the serum MalonDiAldehyde (MDA) levels (nmol/ml) were significantly higher in pre-hypertensive (3.74±0.33) and hypertensive (4.7±0.38) compared to normotensive subjects (3.05±0.38). The Superoxide Dismutase (SOD) activity (U/ml) was higher in subjects with normal blood pressure (12.67±2.31) than pre-hypertensive (11.16±2.43) and hypertensive subjects (8.98±2.32). The MDA had a significant positive correlation, and SOD had a negative association with waist-hip ratio, systolic blood pressure, diastolic blood pressure, fasting blood sugar, high-density lipoprotein, and state and trait anxiety. The present study confirmed that pre-hypertensive and hypertensive subjects suffered from more oxidative stress than normotensive subjects.

scholarly journals Current Trends in the Treatment of Hypertension: Focus on Improving Prognosis. The Capabilities of an Amlodipine/Telmisartan Single-Pill Combination

2020 ◽  
Vol 15 (6) ◽  
pp. 906-917
Author(s):  
O. D. Ostroumova ◽  
A. I. Kochetkov
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Antihypertensive Drugs ◽  
Pressure Control ◽  
Fixed Dose ◽  
Angiotensin Ii Receptor Blocker ◽  
Organ Protection ◽  
Modern Approach ◽  
Hypertensive Patients ◽  
Single Pill

Nowadays, the modern approach to antihypertensive therapy is to prescribe in the most hypertensive patients fixed-dose combinations of antihypertensive drugs as initial therapy. This concept is reflected in the latest revisions of European and Russian guidelines for the management of arterial hypertension (AH). Above mentioned principle is referred as “single-pill combination” strategy and is given high priority in clinical practice with a high evidence level. According to this approach, one of the possible first line single-pill combinations is the combination of an angiotensin II receptor blocker and a calcium channel blocker. In both classes, the reference and the best representatives include, respectively, telmisartan and amlodipine, as a result of broad experience in their practical application and, most importantly, extensive body of evidence regarding to its effectiveness and safety. Both antihypertensive drugs are distinguished by an extra-longstanding antihypertensive effect that exceeds such one of other representatives in their classes, thereby a stable blood pressure control throughout the day is realized, and most importantly, in the early morning hours, that are the most dangerous in terms of adverse cardiovascular and cerebrovascular events. Another important telmisartan and amlodipine characteristics is their targetorgan protective properties, which is realized at all the levels. In addition, telmisartan has a unique ability to activate PPAR-у-receptors and improves the carbohydrate metabolism and lipid profile, which is advantageous in patients with concomitant metabolic syndrome and diabetes mellitus. The telmisartan and amlodipine features and their proven ability to improve prognosis in hypertensive patients served as background for creating a singlepill combination of these antihypertensive drugs, which fully meet with the requirements of current clinical guidelines for AH management and in which these drugs synergistically coupling resulting in more effective blood pressure control, increases the reliability of target-organ protection, and also improves the therapy safety profile.

scholarly journals Evaluation of Sympathetic Nerve Function Status in Hypertensive Patients

2016 ◽  
Vol 12 (1) ◽  
pp. 38-43
Author(s):  
Rehnuma Tabassum ◽  
Sangita Mithun ◽  
SM Nurul Irfan
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Essential Hypertension ◽  
Autonomic Nerve ◽  
Control Group ◽  
Nerve Function ◽  
Hypertensive Patients ◽  
Cardiovascular Morbidity And Mortality ◽  
Normotensive Subjects

Introduction: Hypertension is independent and the most powerful predictor of cardiovascular morbidity and mortality. Sympathetic overdrive may be related to essential hypertension. Heart Rate Variability (HRV) analysis is one of the most quantitative markers of autonomic activity in hypertensive patients. Objective: To assess the cardiac autonomic nerve function status by heart rate variability in essential hypertension. Materials and Methods: This cross sectional study was carried out to observe the HRV in 60 hypertensive male patients with age ranging from 40-60 years (group B) in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU) from 1st July 2008 to 30th June 2009. Based on treatment, hypertensive patients were divided into B1 (untreated patients on their 1st day of diagnosis) and B2 (patients with antihypertensive therapy for less than 5 years). For comparison, 30 apparently healthy normotensive subjects (group A) matched by age sex were also studied. The study group was selected from the Out Patient Department of Cardiology, BSMMU, Dhaka and the control group was selected by personal contact. Heart Rate Variability parameters were assessed by Polygraph (RMS Polyrite D, version2.2) and for statistical analysis Independent sample t-test, One-way ANOVA test, Chi-square test and Pearson’s correlation coefficient tests were done as applicable. Results: LF/HF(Low Frequency/High Frequency) ratio and LF norm (normalized unit) were significantly (p<0.001) higher and HF norm was significantly (p<0.001) lower in untreated hypertensive patients in comparison to those of healthy normotensive subjects. parameters were observed between treated hypertensive and healthy control subjects. The LF/HF ratio and LF norm showed positive correlations and HF norm showed negative correlations with SBP (systolic blood pressure) and DBP (diastolic blood pressure) in both the hypertensive groups. However, all these findings were more marked in untreated hypertensive patients than those of treated group. Conclusion: Hypertensive patients may have sympathovagal imbalance and is usually characterized by higher sympathetic as well as lower vagal modulation of the heart rate. Journal of Armed Forces Medical College Bangladesh Vol.12(1) 2016: 38-43

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