scholarly journals Epidemiological, clinical and laboratory profile of dermatopathies of household dogs and cats in a semi-arid region of Northeast Brazil

2021 ◽  
Vol 10 (14) ◽  
pp. e229101421843
Author(s):  
Juliany Nunes dos Santos ◽  
Evelyn Carla da Frota Rocha ◽  
Joiciglecia Pereira dos Santos ◽  
Valesca Ferreira Machado de Souza ◽  
Danilo Rocha de Melo ◽  
...  

The present study aims to determine the epidemiological, clinical and laboratorial profile of the dermatopathies that affect dogs and cats living in a semi-arid area in the Northeast of Brazil. Seventy-eight dogs and cats consulted at the Veterinary Hospital with dermatological complaints were included in this study. Skin lesions were characterized with respect to morphology, appearance, and distribution, an epidemiological questionnaire was applied, and samples were collected for complementary examination. The diagnosis was confirmed by parasitological and microbiological tests.  There was a predominance of the canine species (93.6%), of young animals (46.3%), and of animals of undefined breeds (61.5%).  It was observed that 29.5% of the affections were of fungal aetiology, 14.1% were bacterial, 3.9% were scabies. In 5.1% of the cases there were associations between different pathogens, and in 47.4% the laboratory examination was negative for the pathogens investigated. The most frequent clinical manifestations included alopecia (74.4%), pruritus (61.6%) and erythema (43.6%), distributed mainly in the dorsal-ventral region (36.1%) or even disseminated (43.1%). With respect to One Health, 51.3% (40/78) of the owners reported that they did not know what "zoonoses" were.  Dermatopathies have been shown to be important disorders, especially the mycotic and bacterial diseases. Atypical cases of infections motivated by pathogens little described in the literature as etiologic agents of dermatopathies in dogs and cats were observed.  

Author(s):  
Takoua Ben Hlel ◽  
Feten Belhadj ◽  
Fatih Gül ◽  
Muhammed Altun ◽  
Ayşe Şahin Yağlıoğlu ◽  
...  

Background:: Luffa cylindrica is a plant that is widely distributed in Africa and Asia and it can be grown in regions with tropical or subtropical climates. Few patents dealt with Loofah biological properties, including some functional foods formulated from its leaves. Objective:: This study aimed to structurally and functionally characterize the bioactive compounds of L. cylindrica leaves grown in two different environments. Methods:: The extracts of L. cylindrica leaves collected from two Tunisian locations: Essouasi (LE), a semi-arid region and Medenine (LM) an arid region, were investigated for their phenolic compounds and fatty acids using HPLC/TOF-MS and GCMS techniques respectively. Furthermore, the antioxidant capacity was evaluated with DPPH, Chelating effect, Hydroxyl radical and Superoxide anion scavenging activities while the anticancer activity against HeLa cell lines was assessed using xCELLigence real time cell analyzer and lactate dehydrogenase cytotoxicity assay. Results:: The antiproliferative capacity of both extracts was time and dose-dependent with LE presenting the lowest HeLa cell index (CI = 0.035 ± 0.018, 250 μg/ml). LE also showed the best cytotoxic capacity (56.49 ± 0.8%) and antioxidant potential (IC50 = 54.41 ± 1.12 μg/ml for DPPH and 12.12 ± 0.07 μg/ml for chelating effet). 14 phenolic compounds were detected in LE with ferulic acid being the major compound (5128.5 ± 4.09 μg Phenols/g) while LM had only 6 phenolics. GCMS analysis showed the presence of omega-3 fatty acids in LE. Conclusions:: Our findings suggest that L. cylindrica leaves, especially when collected from semi-arid regions, are promising for formulating nutraceuticals of interest.


2020 ◽  
Vol 16 (1) ◽  
pp. 33-42 ◽  
Author(s):  
Alexander K.C. Leung ◽  
Joseph M. Lam ◽  
Kin F. Leong

Background: Scabies is a skin disease caused by an obligate human parasite mite Sarcoptes scabiei var. hominis. Children under the age of two and elderly individuals are at the greatest risk. Knowledge of this condition is important for an early diagnosis to be made and treatment to be initiated. Objective: The review aimed to familiarize physicians with the clinical manifestations, diagnosis, evaluation, and management of scabies. Methods: A search was conducted using Pubmed with the built-in "Clinical Queries" tool. The search term "Scabies" was used. The categories of "epidemiology", "diagnosis", "therapy", "prevention" and "prognosis" had a limited scope for primary clinical studies. Meta-analyses, randomized controlled trials, clinical trials, observational studies, and reviews were included. Only papers published in the English language were included. A descriptive, narrative synthesis was provided of the retrieved articles. Results: Worldwide, scabies affects 200 to 300 million individuals annually. The average prevalence is estimated to be 5 to 10% in children of developing countries. Transmission usually occurs after close prolonged skin-to-skin contact. Classic scabies is characterized by an erythematous papular eruption, serpiginous burrows, and intense pruritus. Sites of predilection include the webs of the fingers, volar wrists, lateral aspects of fingers, extensor surfaces of elbows and knees, waist, navel, abdomen, buttocks, groins, and, genitals. A clinical diagnosis of classic scabies can be made on the basis of the history and clinical findings. Other clinical variants include crusted scabies, nodular scabies, and bullous scabies. Finding the mite, ova, or fecal pellets on microscopic examination of scrapings taken from skin lesions confirms the diagnosis of scabies infestation. For eradication of scabies mites, the drugs of choice are topical permethrin and oral ivermectin. Conclusion: Scabies is a highly contagious parasitic cutaneous disease that is stigmatising and debilitating. Increased awareness, accurate diagnosis, and prompt treatment are essential for the effective control of scabies and for the prevention of the spread of the disease.


2021 ◽  
Vol 24 ◽  
pp. e00367
Author(s):  
Patrick Filippi ◽  
Stephen R. Cattle ◽  
Matthew J. Pringle ◽  
Thomas F.A. Bishop

Atmosphere ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 927
Author(s):  
Jamshad Hussain ◽  
Tasneem Khaliq ◽  
Muhammad Habib ur Rahman ◽  
Asmat Ullah ◽  
Ishfaq Ahmed ◽  
...  

Rising temperature from climate change is the most threatening factor worldwide for crop production. Sustainable wheat production is a challenge due to climate change and variability, which is ultimately a serious threat to food security in Pakistan. A series of field experiments were conducted during seasons 2013–2014 and 2014–2015 in the semi-arid (Faisalabad) and arid (Layyah) regions of Punjab-Pakistan. Three spring wheat genotypes were evaluated under eleven sowing dates from 16 October to 16 March, with an interval of 14–16 days in the two regions. Data for the model calibration and evaluation were collected from field experiments following the standard procedures and protocols. The grain yield under future climate scenarios was simulated by using a well-calibrated CERES-wheat model included in DSSAT v4.7. Future (2051–2100) and baseline (1980–2015) climatic data were simulated using 29 global circulation models (GCMs) under representative concentration pathway (RCP) 8.5. These GCMs were distributed among five quadrants of climatic conditions (Hot/Wet, Hot/Dry, Cool/Dry, Cool/Wet, and Middle) by a stretched distribution approach based on temperature and rainfall change. A maximum of ten GCMs predicted the chances of Middle climatic conditions during the second half of the century (2051–2100). The average temperature during the wheat season in a semi-arid region and arid region would increase by 3.52 °C and 3.84 °C, respectively, under Middle climatic conditions using the RCP 8.5 scenario during the second half-century. The simulated grain yield was reduced by 23.5% in the semi-arid region and 35.45% in the arid region under Middle climatic conditions (scenario). Mean seasonal temperature (MST) of sowing dates ranged from 16 to 27.3 °C, while the mean temperature from the heading to maturity (MTHM) stage was varying between 12.9 to 30.4 °C. Coefficients of determination (R2) between wheat morphology parameters and temperature were highly significant, with a range of 0.84–0.96. Impacts of temperature on wheat sown on 15 March were found to be as severe as to exterminate the crop before heading. The spikes and spikelets were not formed under a mean seasonal temperature higher than 25.5 °C. In a nutshell, elevated temperature (3–4 °C) till the end-century can reduce grain yield by about 30% in semi-arid and arid regions of Pakistan. These findings are crucial for growers and especially for policymakers to decide on sustainable wheat production for food security in the region.


2021 ◽  
Vol 780 ◽  
pp. 146500
Author(s):  
Ajit T. Singh ◽  
C.M. Laluraj ◽  
Parmanand Sharma ◽  
B.L. Redkar ◽  
Lavkush Kumar Patel ◽  
...  

2021 ◽  
Vol 53 (4) ◽  
Author(s):  
Maria Samires Martins Castro ◽  
Delano de Sousa Oliveira ◽  
Raquel Oliveira dos Santos Fontenelle ◽  
Ana Paula Araújo do Nascimento ◽  
Robson Mateus Freitas Silveira ◽  
...  

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