scholarly journals Revendo o tratamento para pneumonia causada por Staphylococcus aureus resistente à meticilina

2022 ◽  
Vol 11 (1) ◽  
pp. e8411124338
Author(s):  
Márcia Farsura de Oliveira ◽  
Caroline Silva de Araujo Lima ◽  
Rômulo Daniel Sanches ◽  
Jemerson Costa da Silva ◽  
Thaísa Munique Ferreira Costa de Oliveira ◽  
...  
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Lower Risk ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Length Of Hospital Stay ◽  
Public Health Problem ◽  
Invasive Infections ◽  
Pros And Cons ◽  
The Individual ◽  
Resistance Rates

Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) can cause several infections, both dermatological and invasive infections, such as pneumonia, empyema and sepsis. Due to its importance and pathogenicity, it is considered a worldwide public health problem, which implies the need to search for more efficient therapeutic regimens. Specifically for the treatment of MRSA pneumonia, vancomycin and linezolid are the main drugs used. Objective: The main objective of this study was to compare the two drugs in terms of their effectiveness in the treatment of MRSA pneumonia, through a review of the most recent aspects of the literature. Methodology: Through a narrative review, the pros and cons of each therapeutic intervention were investigated, as well as the individual pharmacological aspects and the pathophysiology of the bacterial infection in question. Conclusion: Finally, it was concluded that linezolid is superior to vancomycin, with better rates of reduced mortality and length of hospital stay, along with a lower risk of complications and adverse events, in addition to greater therapeutic flexibility, better cost-effectiveness and lower resistance rates.

scholarly journals The first isolation of Panton-Valentine leukocidin (PVL) positive community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) in Russia

2007 ◽  
Vol 12 (11) ◽  
Author(s):  
T Baranovich ◽  
V Potapov ◽  
T Yamamoto
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Public Health Problem ◽  
The United States ◽  
Important Public Health Problem ◽  
Methicillin Resistant ◽  
Important Public Health ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin

Since the first report of pediatric deaths in 1997-1999 in the United States, community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has become an increasingly important public health problem worldwide.

scholarly journals Community-Associated Methicillin-ResistantStaphylococcus aureusLacking PVL, as a Cause of Severe Invasive Infection Treated with Linezolid

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Catarina Gouveia ◽  
Alexandra Gavino ◽  
Ons Bouchami ◽  
Maria Miragaia ◽  
Luis Varandas ◽  
...  
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Synovial Fluid ◽  
Public Health Problem ◽  
Invasive Infection ◽  
Limited Information ◽  
Invasive Infections ◽  
Sport Athlete ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin

Community-associated methicillin-resistantStaphylococcus aureus(CA-MRSA) is an emerging public health problem worldwide. Severe invasive infections have been described, mostly associated with the presence of Panton-Valentine leukocidin (PVL). In Portugal limited information exists regarding CA-MRSA infections. In this study we describe the case of a previously healthy 12-year-old female, sport athlete, who presented to the hospital with acetabulofemoral septic arthritis, myositis, fasciitis, acetabulum osteomyelitis, and pneumonia. The MRSA isolated from blood and synovial fluid was PVL negative and staphylococcal enterotoxin type P (SEP) and type L (SEL) positive, with a vancomycin MIC of 1.0 mg/L and resistant to clindamycin and ciprofloxacin. The patient was submitted to multiple surgical drainages and started on vancomycin, rifampicin, and gentamycin. Due to persistence of fever and no microbiological clearance, linezolid was started with improvement. This is one of the few reported cases of severe invasive infection caused by CA-MRSA in Portugal, which was successfully treated with linezolid. In spite of the severity of infection, the MRSA isolate did not produce PVL.

scholarly journals Methicillin-Resistant Staphylococcus Aureus (MRSA) in Cattle: Epidemiology and Zoonotic Implications

2014 ◽  
Vol 2 (1) ◽  
pp. 29-33 ◽  
Author(s):  
Lok Raj Joshi ◽  
Shiva Prasad Devkota
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Skin Diseases ◽  
Current Knowledge ◽  
Public Health Problem ◽  
Methicillin Resistant ◽  
Significant Public Health Problem ◽  
Significant Public Health ◽  
Mrsa Infection

Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a significant public health problem both in human and veterinary medicine. Strains of S. aureus resistant to β-lactam antibiotics are known as Methicillin-resistant Staphylococcus aureus (MRSA). Overuse of antibiotics has been ascribed for MRSA emergence. MRSA in cattle was first reported in 1975. Since then, many literatures describing MRSA in cattle have been published. MRSA causes incurable intra-mammary infection and skin diseases in cattle. In severe cases, it causes deep-seated infections like endocarditis and osteomyelitis.  MRSA got zoonotic importance when scientists suggested the possibility of cattle serving as reservoirs for human MRSA infection. In this article, we review the current knowledge of MRSA in cattle and its zoonotic implications.DOI: http://dx.doi.org/10.3126/ijasbt.v2i1.9861Int J Appl Sci Biotechnol, Vol. 2(1): 29-33

scholarly journals First cases of infections caused by Panton-Valentine leukocidin positive community-acquired methicillin-resistant Staphylococcus aureus in Bulgaria

2007 ◽  
Vol 12 (26) ◽  
Author(s):  
D Nashev ◽  
L Bizeva ◽  
K Toshkova
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Health Problem ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Methicillin Resistant ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin

Infections caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) have emerged as a major public health problem worldwide.

scholarly journals CIRCULATING CLONES OF COMMUNITY-ACQUIRED METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (CA-MRSA) IN WESTERN AUSTRALIA IN THE PAST 11 YEARS (2002-2013)

2016 ◽  
Vol 78 (5) ◽  
Author(s):  
A. M. Setiawan
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Disease Prevention ◽  
Infection Control ◽  
Western Australia ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
Health Concerns ◽  
The Past ◽  
Mrsa Strains

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most complicated problems in infection control and disease prevention. Imported strains or group of similar strains called clones were introduced from other states within Australia and also from other countries. Western Australia (WA) MRSA clones known to be the most predominant clones circulating in Western Australia (WA). However, MRSA strains originally from other states and countries outside Australia (imported) have increased in number in the last decades. The aim of this study was to examine the epidemiology of CA MRSA clones in Western Australia for the past 11 year’s period (2003-2013). There were 10 predominant clones of CA-MRSA circulating in WA with WA MRSA-1 (32,82%), Queensland (22,67 %) and WA MRSA-2 (22,67 %) clones as the top three predominant clones. The percentage of PVL positive CA-MRSA clones such as Queensland (Qld) clone has been increasing significantly (R2=0,67) from 2,38 % in 2002 to 25,69% in 2013. In contrast, the percentages of two major PVL negative clones, WA MRSA-1 and WA MRSA 2, have been decreasing nearly by half from 52,38 % to 27,71 % and 30,95 % to 16,59 % respectively in the last 11 years. PVL positive clones have been introduced in WA from other states and overseas in the last eleven years. Due to the virulence factor of PVL toxin, the emergence of PVL positive CA-MRSA should be considered as public health concerns.

Loneliness and aging in China–a public health problem in need of solutions

2014 ◽  
Vol 26 (11) ◽  
pp. 1771-1772 ◽  
Author(s):  
Shulin Chen ◽  
Yeates Conwell ◽  
Helen Fung Kum Chiu
Keyword(s):  
Public Health ◽  
Mental Health ◽  
Older Adults ◽  
Social Relationships ◽  
Social Connectedness ◽  
Public Health Problem ◽  
Physical And Mental Health ◽  
Research Attention ◽  
Her Family ◽  
The Individual

Loneliness is a common, distressing feeling that results when one perceives his/her social relationships and supports as inadequate. Social connectedness refers to the relationships between the individual and his or her family, friends, community, and other supports. Neither loneliness nor social connectedness has received enough research attention, in particular with regard to older adults’ physical and mental health.

Predicting Methicillin-Resistant Staphylococcus aureus (MRSA) Bloodstream Infection Incidence Rates using Canadian Nosocomial Infection Surveillance Program (CNISP)

2021 ◽  
Vol 2 (2) ◽  
Author(s):  
Jona Gjevori ◽  
Kahina Abdesselam
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Nosocomial Infection ◽  
Bloodstream Infection ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Incidence Rates ◽  
Surveillance Program ◽  
Methicillin Resistant ◽  
Infection Surveillance ◽  
Healthcare Associated

Methicillin-Resistant Staphylococcus aureus (MRSA) is among the most prevalent nosocomial pathogens globally, causing significant morbidity, mortality, and healthcare costs. MRSA bloodstream infection (BSI) incidence rates in Canadian hospitals have significantly risen by almost 60% and have a mortality of over 20% upon Intensive Care Unit admission. MRSA is believed to be spread through healthcare workers; thus, high hand hygiene compliancy in addition to environmental cleaning are the cornerstone countermeasures to disrupting its transmission. The Public Health Agency of Canada (PHAC), in collaboration with the Canadian Nosocomial Infection Surveillance Program (CNISP), conducts national, sentinel surveillance on healthcare-associated infections like MRSA. As a Student Epidemiologist, I developed a research proposal detailing two study objectives: 1) develop a regression model to predict all incident MRSA BSI rates among acute-care hospitals in Canada using CNISP MRSA BSI incident cases from 2000 to 2019, and 2) create a compartmental (Susceptible-Infected-Recovered-Deceased) model to determine the impact of various Infection Prevention and Control (IPC) measures on the risk of healthcare-associated MRSA BSI transmission specifically. This study hopes to demonstrate that proper IPC compliance is associated with lower incident MRSA BSI rates with the goal being to produce a manuscript draft by 2021. MRSA poses a serious threat to patient safety globally and is becoming a growing national public health concern in Canada; determining which IPC strategy is most effective at disrupting MRSA transmission is essential to reducing incidence and mortality rates.

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