scholarly journals Perspectives on COVID-19 therapies: conflicts and consensus

2020 ◽  
Vol 9 (9) ◽  
pp. e85997019
Author(s):  
Kaline Romeiro ◽  
Régida Cléa da Silva Batista ◽  
Luciana Gominho ◽  
Caio Vinícius Batista de Arruda ◽  
Antonio Carlos Moura ◽  
...  

The chronology of COVID-19 infections shows us that the first cases were reported in December 2019. A number of patients were admitted to hospitals with a respiratory disease of an unknown etiology in Wuhan, Hubei Province, China. The patients presented symptoms such as coughing, persistent fever, sore throat and pneumonia. The respiratory infection situation got worse rapidly and had a very fast spread. Soon after, it was reported that the causing agent of the disease had been confirmed as the novel Coronavirus (SARS-CoV-2), which belongs to the subfamily Orthocoronavirinae, of the family Coronaviridae in the order Nidovirales. On January 7, 2020, the disease was named as Coronavirus Disease 2019 (COVID-19) by the World Health Organization (WHO). Chloroquine (CQ), Hydroxychloroquine (HCQ), Remdesivir, Heparin, Convalescent Plasma, Corticosteroid, Anticoagulants, Lopinavir, Ritonavir, Ivermectin and Nitazoxanide are some of the drugs on the market that are being tested to combat COVID-19. The purpose of this literature review is to analyze studies regarding the healing potential of these drugs for COVID-19.  Some researchers about the effectiveness of these medications, the success rate on viral diseases and its action potential by different mechanisms. Thus, given the researches analyzed in this study, it was evident for most authors that these drugs are promising treatments for COVID-19, while the vaccine is not manufactured and available.

2020 ◽  
Vol 3 (Special-1) ◽  
pp. 103-120 ◽  
Author(s):  
Vidhan Chand Bala ◽  
Punet Kumar

Initially recognized of COVID-19 within the world in 2019, the World Health Organization situational report from May 22nd, 2020, globally, there is a complete of 5,204,508 confirmed cases, with 212 countries being affected by the novel coronavirus. 2019 novel coronavirus (SARS-CoV-2) is that the seventh member of the family of coronaviruses is enveloped viruses with a positive sense, single-stranded RNA genome. The SARS-CoV-2 may be a �-CoV of group 2B there is 70% comparability in genetic sequence to SARS-CoV. The source of the new coronavirus infection has been resolved as bats. With whole-genome sequences of SARS-CoV-2 is 96% comparatively at the whole-genome level to a bat coronavirus. Mechanisms of transmission are concluded to incorporate contact, droplet, and possibly airborne under certain circumstances supported ancient experiences associated with SARS-CoV outbreaks. Although antiretroviral therapy is being widely used everywhere the globe for such patents, effects at finding a SARS-CoV vaccine haven�t succeeded so far.


Author(s):  
Indri Seta Septadina

Viruses are one of the causes of infectious diseases that need to be watched out for. In the last 20 years, several viral diseases have caused epidemics such as severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002-2003, influenza H1N1 in 2009 and Middle East Respiratory syndrome (MERS-CoV) which was first identified in Saudi Arabia in year 2012. On December 31, 2019, China reported a case of mysterious pneumonia of unknown cause. Within 3 days, the number of patients with these cases was 44 patients and continues to increase until now there are millions of cases. Initially, the epidemiological data showed that 66% of patients were related to or exposed to a seafood market or live market in Wuhan, Hubei Province, China. Samples of isolates from patients were studied with the results showing the presence of coronavirus infection, a new type of betacoronavirus, named 2019 novel Coronavirus (2019-nCoV). On February 11, 2020, the World Health Organization named the new virus SARS-CoV-2 and the disease name as Coronavirus Disease 2019 (COVID-19). The corona virus is the main pathogen causing an outbreak of respiratory disease. On March 11, 2020, WHO announced that COVID-19 was becoming a pandemic in the world.


2020 ◽  
Vol 3 (3) ◽  
pp. 01-02
Author(s):  
Khadiga Ismail

COVID-19 has high transmissibility and infectivity among human. On January 30, 2020, the World Health Organization (WHO) in an effort to slow down the global spread of the virus declared the outbreak, “A global public health emergency of international concern". The skin manifestations of the novel coronavirus COVID-19 were not recognized at the early stages of the pandemic but have received much recent attention in scientific journals. Reported manifestations range from pseudo-chilblains to a morbilliform (measles-like) exanthem, urticaria, vesicular eruptions, a dengue-like petechial rash and ovate scaling macules, and plaques mimicking pityriasis rosea.


2020 ◽  
Vol 8 ◽  
Author(s):  
Xuanzhen Cen ◽  
Dong Sun ◽  
Ming Rong ◽  
Gusztáv Fekete ◽  
Julien S. Baker ◽  
...  

Recently, an unprecedented coronavirus pandemic has emerged and has spread around the world. The novel coronavirus termed COVID-19 by the World Health Organization has posed a huge threat to human safety and social development. This mini review aimed to summarize the online education mode and plans for schools to resume full-time campus study in China during COVID-19. Chinese schools have made significant contributions to the prevention and control of the transmission of COVID-19 by adopting online learning from home. However, normal opening and classroom teaching have been affected. For education systems at all levels, online education may be an effective way to make up for the lack of classroom teaching during the epidemic. To protect staff and students from COVID-19, the timing of students returning to full-time campus study needs to be considered carefully. Reviewing and summarizing of the Chinese education system's response to the virus would be of great value not only in developing educational policy but also in guiding other countries to formulate educational countermeasures.


2020 ◽  
pp. 1-4
Author(s):  
Naveen Kishoria ◽  
S.L Mathur ◽  
Veeram Parmar ◽  
Rimple Jeet Kaur ◽  
Harish Agarwal ◽  
...  

A cluster of pneumonia cases of unknown etiology was reported from the city of Wuhan, in the Hubei province of China, in December 2019. A novel coronavirus, named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the causative agent of the disease which was subsequently termed as the coronavirus disease (COVID-19) by the World Health Organization (WHO). SARS-CoV-2 mainly affects the lower res-piratory tract and manifests as pneumonia in humans.


Author(s):  
Renée Belliveau

After the World Health Organization declared the spread of the novel coronavirus (COVID-19) a global pandemic in March 2020, they cautioned of another outbreak: an “infodemic.” This study examines how online search engines are influencing the global spread of immunization information about COVID-19. It aims to address the various ways in which search technology is shaping users’ perceptions of the pandemic and to measure the credibility of the sources they provide.


2021 ◽  
Vol 24 (2) ◽  
pp. 173-177
Author(s):  
Abraham Cyril Issac

Abstract The world is battling out the pandemic of Covid-19. The World Health Organization (WHO) is jointly acting upon the same daily, which is evident from the ‘situation reports.’ The pandemic, which saw its origin in Wuhan, has spread across the world within a short span of under two months. While the pandemic has effectively instilled a situation of cordon sanitaire across the globe, the virus seems to show no respite. This study collates different sources and establishes the human tendency of knowledge hiding as the prime reason for the spread of such colossal magnitudes. The study underlines the notion by examining some of the critical cases and situations that have unfolded in the very recent past.


2020 ◽  
Vol 148 ◽  
Author(s):  
Chen Ling ◽  
Xianjie Wen

Abstract The outbreak of novel coronavirus pneumonia (coronavirus disease 2019 (COVID-19)), declared as a ‘global pandemic’ by the World Health Organization (WHO), is a public health emergency of international concern (PHEIC). The outbreak in multiple locations shows a trend of accelerating spread around the world. China has taken a series of powerful measures to contain the spread of the novel coronavirus. In response to the COVID-19 pandemic, in addition to actively finding effective treatment drugs and developing vaccines, it is more important to identify the source of infection at the community level as soon as possible to block the transmission path of the virus to prevent the spread of the pandemic. The implementation of grid management in the community and the adoption of precise management and control measures to reduce unnecessary personnel movement can effectively reduce the risk of pandemic spread. This paper mainly describes that the grid management mode can promote the refinement and comprehensiveness of community management. As a management system with potential to improve the governance ability of community affairs, it may be helpful to strengthen the prevention and control of the epidemic in the community.


Author(s):  
Nur Hidayah Che Ahmat ◽  
Syafiqah Rahamat ◽  
Susan Wohlsdorf Arendt

The novel Coronavirus disease (COVID-19) first appeared in December 2019 in Wuhan, Hubei Province China before emerging in neighbouring countries in early 2020. The World Health Organization (WHO) declared COVID-19 a pandemic when the spreading of the virus started accelerating in many parts of the world and killing thousands of people. As of 22nd May 2021, there were more than 166 million confirmed cases with more than 147 million recovered and nearly 3.5 million deaths (Worldometers, n.d.). According to the WHO (2020) and Centers for Disease Control and Prevention (2020), the virus easily spreads through coughing and sneezing. Therefore, many countries implemented social distancing between individuals and various other restriction orders or recommendations (e.g., stay-at-home policies, closure of non-essential businesses) to help curb virus spread. How governments in each country reacted to control the spread of the virus appeared crucial to mitigate public health and economic impacts. Keywords: Foodservice, Hospitality, Hotel, Malaysia, Pandemic


2020 ◽  
Vol 52 (8) ◽  
pp. 1483-1486
Author(s):  
Xuebin Wei ◽  
Mingshu Wang ◽  
Menno-Jan Kraak

On March 11, 2020, the World Health Organization announced the novel coronavirus disease (COVID-19) as a pandemic. Despite an increasing number of international attempts using maps to present and communicate COVID-19-related information in different organizations, most map products have only used the presentation function of maps. Against this backdrop, we offer an automatically daily-updated, color-blind-friendly, Tableau-based interactive dashboard to demonstrate where and how different countries are fighting against COVID-19. The dashboard allows users to specify countries they want to compare and aggregate relevant data on a daily, weekly, or monthly basis.


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