Radiоtherapy as salvage therapy for kaposiform hemangioendothelioma and giant angioma associated with Kasabach–Merritt phenomenon

2021 ◽  
pp. 12-17
Author(s):  
R. I. Khabarova ◽  
S. A. Kulyova ◽  
S. V. Ivanova ◽  
S. N. Novikov ◽  
E. D. Gumbatova ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Salvage Therapy ◽  
Vascular Anomaly ◽  
Vascular Anomalies ◽  
Diagnosis And Treatment ◽  
Vascular Tumors ◽  
Kaposiform Hemangioendothelioma ◽  
Timely Diagnosis ◽  
Life Threatening

The Kasabach–Merritt phenomenon is a rare thrombocytopenic consumption of coagulopathy that occurs against the background of such vascular anomalies as kaposiform hemangioendothelioma and giant angioma. Timely diagnosis and treatment of Kasabach–Merritt syndrome which includes therapy for vascular tumors and life‑threatening conditions are critical in resolving this rare vascular anomaly. The aim of the study is to analyze radiation therapy as salvage therapy for kaposiform hemangioendothelioma and giant angioma associated with the Kasabach–Merritt phenomenon.

scholarly journals Peripheral Arteriovenous Malformations: Imaging and Endovascular Management Strategies

2021 ◽  
Author(s):  
Virender Malik ◽  
Harshith Kramadhari ◽  
Jawahar Rathod ◽  
Yadav W. Munde ◽  
Uday Bhanu Kovilapu
Keyword(s):  
Arteriovenous Malformation ◽  
Vascular Malformation ◽  
Management Strategies ◽  
Treatment Strategies ◽  
Vascular Anomaly ◽  
Classification Systems ◽  
Vascular Anomalies ◽  
Final Decision ◽  
Life Threatening

AbstractThe peripheral high-flow vascular malformation (HFVM) comprises arteriovenous malformation (AVM) and fistula (AVF), shows varied clinical presentation (ranging from subtle skin lesion to life-threatening congestive heart failure), and frequently poses diagnostic and therapeutic challenges. Importance of assigning a specific diagnosis to the vascular malformation cannot be overstated, as the treatment strategy is based on the type of vascular anomaly. Although the International Society for the Study of Vascular Anomalies (ISSVA) classification system is the most commonly accepted system for classifying congenital vascular anomalies in clinical practice, the Cho–Do et al classification is of utmost help in guiding optimal mode of treatment in peripheral AVM. Although transarterial approach remains the most commonly employed route for peripheral AVM embolization, the role of transvenous and direct percutaneous approach is ever increasing and the final decision on the approach depends on angioarchitecture of the AVM. In this article, we review various commonly employed classification systems for congenital vascular anomalies, and describe clinical features, imaging and treatment strategies for peripheral arteriovenous malformation (PAVM).

scholarly journals Peripheral Vascular Anomalies – Essentials in Periinterventional Imaging

2019 ◽  
Vol 192 (02) ◽  
pp. 150-162 ◽  
Author(s):  
Maliha Sadick ◽  
Daniel Overhoff ◽  
Bettina Baessler ◽  
Naema von Spangenberg ◽  
Lena Krebs ◽  
...  
Keyword(s):  
Therapeutic Approach ◽  
Vascular Malformations ◽  
Vascular Anomaly ◽  
Flow Dynamics ◽  
Vascular Anomalies ◽  
Vascular Tumors ◽  
Slow Flow ◽  
Peripheral Vascular ◽  
Fast Flow ◽  
Selection Of

Background Peripheral vascular anomalies represent a rare disease with an underlying congenital mesenchymal and angiogenetic disorder. Vascular anomalies are subdivided into vascular tumors and vascular malformations. Both entities include characteristic features and flow dynamics. Symptoms can occur in infancy and adulthood. Vascular anomalies may be accompanied by characteristic clinical findings which facilitate disease classification. The role of periinterventional imaging is to confirm the clinically suspected diagnosis, taking into account the extent and location of the vascular anomaly for the purpose of treatment planning. Method In accordance with the International Society for the Study of Vascular Anomalies (ISSVA), vascular anomalies are mainly categorized as slow-flow and fast-flow lesions. Based on the diagnosis and flow dynamics of the vascular anomaly, the recommended periinterventional imaging is described, ranging from ultrasonography and plain radiography to dedicated ultrafast CT and MRI protocols, percutaneous phlebography and transcatheter angiography. Each vascular anomaly requires dedicated imaging. Differentiation between slow-flow and fast-flow vascular anomalies facilitates selection of the appropriate imaging modality or a combination of diagnostic tools. Results Slow-flow congenital vascular anomalies mainly include venous and lymphatic or combined malformations. Ultrasound and MRI and especially MR-venography are essential for periinterventional imaging. Arteriovenous malformations are fast-flow vascular anomalies. They should be imaged with dedicated MR protocols, especially when extensive. CT with 4D perfusion imaging as well as time-resolved 3D MR-A allow multiplanar perfusion-based assessment of the multiple arterial inflow and venous drainage vessels of arterio-venous malformations. These imaging tools should be subject to intervention planning, as they can reduce procedure time significantly. Fast-flow vascular tumors like hemangiomas should be worked up with ultrasound, including color-coded duplex sonography, MRI and transcatheter angiography in case of a therapeutic approach. In combined malformation syndromes, radiological imaging has to be adapted according to the dominant underlying vessels and their flow dynamics. Conclusion Guide to evaluation of flow dynamics in peripheral vascular anomalies, involving vascular malformations and vascular tumors with the intention to facilitate selection of periinterventional imaging modalities and diagnostic and therapeutic approach to vascular anomalies. Key Points:  Citation Format

HEAD AND NECK VASCULAR ANOMALIES OUR CLINICAL EXPERIENCE AND LITERATURE REVIEW.

2020 ◽  
Vol VOLUME 8 (ISSUE 1) ◽  
pp. 1-8
Author(s):  
Arulalan Mathialagan
Keyword(s):  
Literature Review ◽  
Head And Neck ◽  
Venous Malformation ◽  
Neck Region ◽  
Vascular Anomaly ◽  
Vascular Anomalies ◽  
Active Management ◽  
Vascular Tumors ◽  
Tertiary Referral Centre ◽  
Prompt Diagnosis

Abstract Background- Head and neck vascular anomalies are a spectrum of lesion ranging from simple asymptomatic malformations to life-threatening airway vascular tumors. Management of these lesion poses a real challenge to even most experienced otolaryngologists.Systematic evaluation and prompt diagnosis and judicial choice of treatment are essential for proper management of these lesions. Material and methods-A retrospective review of the head and neck vascular anomalies over three years, from 2017 to 2019 in a tertiary referral centre. Clinical features, radiology, treatment and follow-up data were studied.We did a literature review to give a comprehensive analysis regarding the diagnosis and treatment of the vascular anomalies of the head and neck region. Results- A total of 25 patients were managed in our department in two years. Of these 25 patients, three patients had infantile haemangioma(12%), six patient had congenital haemangioma(24%), six patients had lymphatic malformation(24%), four patient had an arteriovenous malformation (16%), and six patient had venous malformation (24%). Sixpatients (24%) underwent surgery as treatment, which includes one case of noninvoluting congenital hemangioma (NICH) of the temporal bone, one facial AVM, twolateral neck lymphangiomas, one skull base lymphangioma and a venous neck malformation. All the infantile h a ema n gi oma s we rema n a g e d w i t h o ra l propranolol, three lymphatic malformations underwent sclerotherapy, while the three Arteriovenous malformations (AVM), 􀃶ve congenital haemangiomas and four Venous malformations (VM) were under observation. Conclusion-Managing a vascular anomaly requires a prompt diagnosis based on the ISSVA classi􀃶cation, patients' symptoms and the location of the lesion. Not all vascular anomaly requires active management. Careful case selection and a multidisciplinary team are essential for adequate management of the vascular anomalies. Key Words: Vascular Malformation, Hemangioma, Lymphangioma

scholarly journals Adrenal crisis: a rare endocrine emergency with challenging diagnosis

2020 ◽  
Vol 9 (10) ◽  
pp. 1612
Author(s):  
Ankit Bhardwaj ◽  
Vivek Singh ◽  
Kaveri Kapoor ◽  
Anil Kem
Keyword(s):  
Case Report ◽  
Diagnosis And Treatment ◽  
Adrenal Crisis ◽  
Timely Diagnosis ◽  
Life Threatening ◽  
Sick Day Rules

Adrenal crisis is a rare life-threatening medical endocrine emergency with non-specific insidious symptoms and challenging diagnosis. An appropriate timely diagnosis and treatment can save life. Although most doctors are educated by “sick day rules,” but are reluctant to start glucocorticoids, increase doses or switch to parental injections. Our case report highlights various aspect of adrenal crisis.

scholarly journals An unusual case of venous varix on forehead

2018 ◽  
Vol 6 (1) ◽  
pp. 314
Author(s):  
Sharadendu Bali ◽  
Sameer Pundeer ◽  
Maneshwar Singh Utaal
Keyword(s):  
Unusual Case ◽  
Valsalva Maneuver ◽  
Vascular Anomaly ◽  
Vascular Anomalies ◽  
General Surgeon ◽  
Medial Margin ◽  
Life Threatening ◽  
Eye Opening ◽  
Venous Varix

Vascular anomalies include a wide number of disorders from a simple birthmark to life threatening entities. One such vascular anomaly is venous varix which is a commonly encountered case by a general surgeon although venous varix occurring on the forehead as being reported here is a rarity. Authors present a case of swelling over forehead at orbital verge which becomes prominent on performing valsalva maneuver. Case is of a 10year old girl brought to OPD with complaints of swelling over the left side of forehead since birth which becomes prominent on valsalva maneuver, with no associated complaints of pain or difficulty in eye opening. On examination, there was a 2cm diameter swelling present over the left forehead just above the medial margin of left eyebrow. CECT Brain showed no bony or intra orbital extension. Patient underwent excision of the varix. Postoperatively patient recovered well and discharged with cosmetic satisfaction.

scholarly journals THE IMPORTANCE OF ACCURATE IMAGING DIAGNOSIS OF A VASCULAR ANOMALY PRIOR TO THE SURGICAL PROCEDURE

2021 ◽  
Vol 68 (2) ◽  
pp. 301-305
Author(s):  
Maria Popescu ◽  
◽  
Gabriel Drăgan ◽  
Alina Oprescu ◽  
◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Treatment Plan ◽  
Contrast Material ◽  
Vascular Anomaly ◽  
Clinical History ◽  
Management Plan ◽  
Vascular Anomalies ◽  
Vascular Tumors ◽  
Imaging Features ◽  
Informed Treatment

The diagnosis of vascular tumors and malformations is usually achieved with clinical history and physical examination. The imaging of these patients has been sufficiently refined to answer pertinent questions when trying to make an accurate differential diagnosis in order to establish an informed treatment plan. The imaging modalities at hand include ultrasound, doppler sonography, magnetic resonance imaging and contrast material enhanced magnetic resonance angiography. We present two cases of different vascular anomalies that were managed according to the clinical aspect, natural history and imaging performed. Moreover, with better understanding of the imaging features, the radiologist has become a key player in the diagnosis and management plan of the vascular anomalies. This is crucial in avoiding misdiagnosis and improper treatment.

Endometriosis and its Ayurvedic perspective

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Vishwesh B. N.
Keyword(s):  
The Body ◽  
Diagnosis And Treatment ◽  
Timely Diagnosis ◽  
Life Threatening

Endometriosis defined as the presence of functioning endometrium, in sights other than uterus. It can be either the endometriosis externa or interna. Externa refers to endometriosis of any part of the body except the myometrium. In interna, the endometriosis is found in the muscle wall of the uterus. All though endometriosis is not considered as a life threatening disease, is a life altering disease that requires timely diagnosis and treatment. This paper intends to review on endometriosis and its Ayurvedic perspective in detail.

scholarly journals Lidocaine: A Local Anesthetic, Its Adverse Effects and Management

Medicina ◽  
2021 ◽  
Vol 57 (8) ◽  
pp. 782
Author(s):  
Entaz Bahar ◽  
Hyonok Yoon
Keyword(s):  
Adverse Effects ◽  
Local Anesthetic ◽  
Local Anesthetics ◽  
Adverse Reactions ◽  
Rapid Diagnosis ◽  
Diagnosis And Treatment ◽  
Allergic Reactions ◽  
Life Threatening

The most widely used medications in dentistry are local anesthetics (LA), especially lidocaine, and the number of recorded adverse allergic responses, particularly of hazardous responses, is quite low. However, allergic reactions can range from moderate to life-threatening, requiring rapid diagnosis and treatment. This article serves as a review to provide information on LA, their adverse reactions, causes, and management.

Sign in / Sign up

Export Citation Format

Share Document