Age and gender characteristics of thoracic aorta elasticity indices in patients with coronary atherosclerosis

2021 ◽  
pp. 34-41
Author(s):  
I. N. Mushkambarov ◽  
N. F. Beresten ◽  
S. B. Tkachenko
Keyword(s):  
Thoracic Aorta ◽  
Coronary Atherosclerosis ◽  
Stiffness Index ◽  
Age Group ◽  
Age And Gender ◽  
Diastolic Velocity ◽  
Compliance Coefficient ◽  
Gender Characteristics ◽  
And Gender ◽  
Near Wall

Background. Ischemic heart disease (CHD) holds a leading position in the structure of causes of general mortality and in the structure of mortality from cardiovascular diseases. We extended the standard echocardiography with assessment of thoracic aorta elasticity to identify markers of the thoracic aorta elasticity worsen associated with coronary atherosclerosis. When analyzing the data, we identified different clinical characteristics of study participants as one of the main reasons for the difficulty in comparing the data with the results of previous studies, which made it necessary to highlight age and gender characteristics of indicators.Aim. To analyze age and gender characteristics of thoracic aorta elasticity indices in patients with coronary atherosclerosis.Material and methods. An observational analytical cross- sectional clinical trial was conducted from 2016 to 2019. Our study included 109 patients aged 39 to 82 years (mean age 65 ± 9 years, median 66 years), who were divided into 2 groups according to the results of invasive coronarography: 64 patients with coronary atherosclerosis and 45 patients without angiographic signs of coronary atherosclerosis. In the group with coronary atherosclerosis average age was 66 ± 8 years (median 66 years). In the group without coronary atherosclerosis average age was 64 ± 9 years (median 66 years). During transthoracic echocardiography, the following were obtained: coefficient of distensibility, compliance coefficient, elasticity (stiffness) module of Peterson, stiffness index of the ascending thoracic aorta; systolic velocity S, early diastolic velocity E, late diastolic velocity A of the near wall of the ascending aorta, flow velocity propagation (FVP) of the descending thoracic. Analysis of age and gender characteristics of thoracic aorta elasticity indices in patients with coronary atherosclerosis was done.Results. An increase in the stiffness index of the ascending thoracic aorta associated with coronary atherosclerosis occurs in the age group 39–66 years, a decrease in the coefficients of extensibility and compliance, an increase in Peterson’s modulus of elasticity (stiffness) of the as cending thoracic aorta — in the age group 67–82 years. A decrease in the E velocity of the near wall of the ascending thoracic aorta and FVP, associated with coronary atherosclerosis, occurs regardless of belonging to the age group, a decrease in the S velocity — in the age group 39–66 years. A decrease in the compliance coefficient of the ascending thoracic aorta, velocity S of the near wall of the ascending thoracic aorta, associated with coronary atherosclerosis, occurs only in men, an increase in the stiffness index — only in women. A decrease in the extensibility coefficient, an increase in the Peterson’s modulus of elasticity (stiffness), a decrease in the E velocity, and a decrease in CRP associated with coronary atherosclerosis occur regardless of gender.Conclusion. Worsening of the thoracic aorta elasticity in patients with coronary atherosclerosis, assessed using echocardiographic technologies, depends on gender and age.

Impact of age and sex on subclinical coronary atherosclerosis in a healthy asian population

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
M Wong ◽  
J Yap ◽  
KK Yeo
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Coronary Artery ◽  
Coronary Atherosclerosis ◽  
Ldl Cholesterol ◽  
Multivariable Analysis ◽  
Asian Population ◽  
Atherosclerotic Cardiovascular Disease ◽  
Age And Gender ◽  
And Gender

Abstract Funding Acknowledgements Type of funding sources: None. Background and Aims The influence of age and gender on clinical atherosclerotic cardiovascular disease is well reported, but literature remains sparse on whether these extend to the disease in its preclinical stage. We aim to report the prevalence, risk-factors and impact of age and gender on the burden of subclinical coronary atherosclerosis in a healthy Asian population. Methods Healthy subjects aged 30-69 years old, with no history of cardiovascular disease or diabetes were recruited from the general population. Subclinical coronary atherosclerosis was quantified via the Coronary Artery Calcium Score (CACS) with CACS of 0 indicating the absence of calcified plaque, 1 to 10 minimal plaque, 11 to 100 mild plaque, and >100 moderate to severe plaque. Results A total of 663 individuals (mean age 49.4 ± 9.2 years, 44.8% male) were included. The prevalence of any CAC was 29.3% with 9% having CAC > 100.  The prevalence was significantly higher in males than females (43.1 vs 18.0%, p < 0.001). These gender differences became increasingly pronounced with increasing age, especially in those with moderate-severe CAC. Multivariable analysis revealed significant associations between increasing age, male, higher blood pressure, increased glucose levels and higher LDL cholesterol levels with the presence of any CAC. LDL cholesterol was more significantly associated with CAC in females compared to males (Pinteraction = 0.022). Conclusions The prevalence of preclinical atherosclerosis increased with age, and was higher in males than females, with gender-specific differences in associated risk factors. These results will better inform individualised future risk management strategies to prevent the development and progression of coronary artery disease within healthy individuals.

scholarly journals Drinkers in the micro-social environment of the inhabitants of Ukraine. Age and gender characteristics

2021 ◽  
pp. 4-11
Author(s):  
Igor Linskiy ◽  
Valerii Kuzminov ◽  
Oleksandr Minko ◽  
Hanna Kozhyna ◽  
Yevheniia Grynevych ◽  
...  
Keyword(s):  
Alcohol Problems ◽  
Subjective Perception ◽  
Age And Gender ◽  
Main Research ◽  
Gender And Age ◽  
Comparison Groups ◽  
Gender Characteristics ◽  
And Gender ◽  
Research Consortium ◽  
Ukrainian Society

The purpose of the work is to determine in the Ukrainian society the scale of harm inflicted by drinkers to other persons, as well as the gender and age characteristics of this harm. In four regions of Ukraine (Kharkiv, Lugansk and Zaporizhzhia regions, Kyiv), during 2018-2020, 1,742 people were examined from three qualitatively different comparison groups: patients with alcohol dependence (393 people); their healthy relatives (274 people) and representatives of the general population (1075 people). The main research tool was the questionnaire of the international research consortium GENAHTO (Gender, Alcohol, and Harms to Others). It was shown that, in general, drinkers are present in the microsocial environment of 27.62 % of the surveyed healthy respondents. Extrapolation of this indicator to the entire population of Ukraine suggests that the total number of people who suffer in one way or another due to the drinkers in their environment is about 11.6 million people. In addition, the drinkers frequency in the environment of respondents can be used to determine the real number of people with alcohol problems in our country. Preliminary calculations indicate that this number is from 1.5 to 2.2 million people. The drinkers frequency in the environment of the respondents significantly depends on the age of the latter. The highest values of this indicator are characteristic of the respondents in the age category 40—59 years old” (31.43 % for men and 41.27 % for women). The subjective perception of harm from drinkers in the environment grows steadily with increasing age of the respondents, while this growth is most pronounced in women.

The Contribution of Videogames to Anti-Social Attitudes and Behaviours amongst Youngsters

2011 ◽  
pp. 237-251
Author(s):  
Olga Albuquerque ◽  
Gillian Grace Moreira
Keyword(s):  
Video Games ◽  
Parental Control ◽  
Social Attitudes ◽  
Video Gaming ◽  
Small Scale ◽  
Age Group ◽  
Simulation Games ◽  
Age And Gender ◽  
Future Studies ◽  
And Gender

Using questionnaires and interviews, the video-gaming habits of 136 youngsters, ranging from the ages of 9 to 15 years, were assessed, taking into consideration their age and gender. It was found that many youngsters are playing games which are not appropriate for their age group, and that long hours are spent at computer screens on these games without parental control or supervision. In fact, most parents do not even know what games their children are playing never mind whether they are rated as suitable for their age group. In addition, differences between boys and girls were significant, allowing us to confirm that boys prefer more action-oriented games while girls choose simulation games. Although the small-scale nature of this study does not allow us to generalise its conclusions, its findings are relevant and can point the way for future studies of this type. The centrality of video games in the lives of children and teenagers today is such that these and the practices they engender need to be taken into account when considering the rise of anti-social, aggressive, and at times violent attitudes and behaviours amongst youngsters.

Gender influence on vasoactive hormones at rest and during a 70° head-up tilt in healthy humans

2002 ◽  
Vol 92 (4) ◽  
pp. 1401-1408 ◽  
Author(s):  
Ghislaine Geelen ◽  
Tomi Laitinen ◽  
Juha Hartikainen ◽  
Esko Länsimies ◽  
Kim Bergström ◽  
...  
Keyword(s):  
Significant Influence ◽  
Upright Position ◽  
Age Group ◽  
Plasma Epinephrine ◽  
Age And Gender ◽  
Men And Women ◽  
Orthostatic Challenge ◽  
Group I ◽  
Head Up Tilt ◽  
And Gender

To evaluate the influence of age and gender on the neuroendocrine control of blood pressure in normal subjects, a 13-min 70° head-up tilt (HUT) was applied after 3 h of recumbency to 109 healthy men and women aged 23–50 yr ( age group I) and 51–77 yr ( age group II). We found that age and gender had a significant influence on plasma norepinephrine (PNE) concentration at baseline and in the upright position. PNE was significantly higher in older men compared with the younger men and women of both age groups, suggesting a divergent age-related activation of the sympathetic nervous system between genders at baseline as well as during a sustained orthostatic challenge. There was no significant influence of age or gender on plasma epinephrine at baseline or during HUT. Plasma renin activity was significantly higher at baseline as well as in the upright position during HUT in elderly men than in women. Age or gender had no influence on plasma vasopressin (PAVP), and, regardless of age, nonhypotensive HUT induced an extremely modest increase in PAVP. The syncopal subjects displayed a hormonal pattern associating increased PNE and a surge in plasma epinephrine and PAVP minutes before syncope during HUT. The orthostatic intolerance appears not to be a feature of healthy aging per se. In healthy subjects, both age and gender modulate markedly the cardiovascular and neuroendocrine responses to an orthostatic challenge and must be taken into consideration, particularly when catecholamine responses are studied.

Symptom CheckList-90-R: Proposed Scales in a Probability Sample of Adolescents from the General Population

2014 ◽  
Vol 17 ◽  
Author(s):  
Elena Felipe-Castaño ◽  
Benito León-del-Barco ◽  
José Antonio López-Pina
Keyword(s):  
Normative Data ◽  
Sampling Error ◽  
Effect Sizes ◽  
Cluster Sampling ◽  
Age Group ◽  
Age And Gender ◽  
Symptom Dimensions ◽  
Probability Sample ◽  
Gender And Age ◽  
And Gender

AbstractTo provide questionnaires for clinical assessment with scales adapted for adolescents would benefit clinical practice as well as research. The aim of this paper is to report normative data for adolescents on the SCL-90-R using a probability sample from the community. The participants were 1,663 adolescents, 845 girls and 818 boys, with an average age of 14.26 (SD = 1.36). They were selected through stratified cluster sampling with groups randomly selected from schools. Sampling error was estimated at 4% with a 95.5% confidence level. Cohen´s d effect sizes are reported for age-group. We found significant differences across participants according to gender and age on SCL-90-R Global Scores and Symptom Dimensions. Thus, we provide normative data, divided according to age and gender.

Co-infection with gonorrhoea and chlamydia: how much is there and what does it mean?

2003 ◽  
Vol 14 (2) ◽  
pp. 109-113 ◽  
Author(s):  
Sarah Creighton ◽  
Melinda Tenant-Flowers ◽  
Christopher B Taylor ◽  
Rob Miller ◽  
Nicola Low
Keyword(s):  
Dual Infection ◽  
Cross Sectional Study ◽  
Heterosexual Men ◽  
Age Group ◽  
Sectional Study ◽  
College Hospital ◽  
Cross Sectional ◽  
Age And Gender ◽  
King's College ◽  
And Gender

A cross-sectional study of new clients with either gonorrhoea or chlamydia attending King's College Hospital in 1998. One thousand two hundred and thirty-nine women and 1141 men had gonorrhoea, chlamydia or both. Overall, 24.2% (124/512) of heterosexual men and 38.5% (136/353) of women with gonorrhoea also had chlamydia ( P<0.001). Of heterosexual males 18.8% (124/660) and 13% (136/1022) of females with chlamydia also had gonorrhoea ( P=0.002). Ethnicity had no effect on the proportion of co-infection after controlling for age and gender. Clients with dual infection were younger than those with either infection alone ( P=0.0001). Over half of women and a quarter of men aged 15 to 19 years were dually infected so testing for both gonorrhoea and chlamydia may be appropriate in this age group in settings outside genitourinary clinics. The high proportion of cases of gonorrhoea that also have chlamydia justifies the policy of epidemiological treatment for chlamydia.

A study of manual toothbrushing skills in children aged 3 to 11 years

2003 ◽  
Vol 27 (1) ◽  
pp. 91-94 ◽  
Author(s):  
Ali Mentes ◽  
Julide Atukeren
Keyword(s):  
Age Groups ◽  
Age Group ◽  
Age And Gender ◽  
Significant Difference ◽  
Study Population ◽  
The Mean ◽  
And Gender

The aim of the study was to evaluate toothbrushing management and ability of children in relation to age and gender. The study population consisted of 75 children and were divided into three equal groups as 3-5, 6-8 and 9-11 years of age.The grip type during toothbrushing was recorded on videotape.The most preferred grip types were distal (73%) followed by power (43%) and oblique grips (29%). There were a statistically significant differences between age groups and the grip types (p&lt;0.001) but no significant difference was seen between boys and girls in grip preferences (p&gt;0.05).The mean duration of toothbrushing was shorter in 3-5 years of age group (28 seconds) than the 6-8 and 9-11 age groups (35 and 47 seconds respectively).

scholarly journals Association Between Cervical Abrasion and Age and Its Influence on Gender - A Retrospective Study

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 441-446
Author(s):  
Nur Liyana Hannah Binti Izham Akmal ◽  
Adimulapu Hima Sandeep ◽  
Revathi Duraisamy
Keyword(s):  
Retrospective Study ◽  
Mechanical Forces ◽  
Age Group ◽  
Cervical Lesions ◽  
Age And Gender ◽  
Tooth Structure ◽  
High Prevalence ◽  
Males And Females ◽  
The Difference ◽  
And Gender

Cervical lesions are often characterized by defects seen in the gingival third of a tooth crown which may be in the facial or lingual surface. Pathological loss of tooth structure caused by factors other than dental caries such as cervical abrasion is referred to as non-carious cervical lesions (NCCL). Cervical abrasion is an example of NCCL in which a constant exposure of the tooth to mechanical forces leads to pathological wearing away of the hard tissues. In most of the cases, cervical tooth lesions are revealed to be more common as the age increases. Several studies have reported the difference in the prevalence of cervical abrasion between males and females. Many reports suggest that cervical abrasion is commonly associated with improper tooth brushing habits. To evaluate the prevalence of cervical abrasion between genders and its influence on age. It is a retrospective study conducted using the case records of Saveetha Dental College and Hospital, Chennai, India from June 2019 to March 2020. Data including the patient’s name, patient’s identification number (PID), age, gender and presence of cervical abrasion were retrieved from the patients’ case records. A total of 742 consecutive case records were retrieved and analysed. Cervical abrasion was observed in 371 individuals of this study. High prevalence of cervical abrasions was seen in males (70.9%) compared to females (29.1%). Most of the cases were observed in individuals within the 41-50 years age group (28.8%), and the least was seen within the 11-20 years age group (0.3%). Within the limits of the study, most of the cervical abrasion cases are recorded in individuals within the 41-50 years age group with higher predilection in males. There is a statistically significant association of cervical abrasion with age and gender.

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