scholarly journals Spinal Capillary and Cavernous Haemangiomas in Developmental Age: Our Experience

2021 ◽  
Vol 2 (4) ◽  
Keyword(s):  
Author(s):  
Maria Fitzgerald ◽  
Michael W. Salter

The influence of development and sex on pain perception has long been recognized but only recently has it become clear that this is due to specific differences in underlying pain neurobiology. This chapter summarizes the evidence for mechanistic differences in male and female pain biology and for functional changes in pain pathways through infancy, adolescence, and adulthood. It describes how both developmental age and sex determine peripheral nociception, spinal and brainstem processing, brain networks, and neuroimmune pathways in pain. Finally, the chapter discusses emerging evidence for interactions between sex and development and the importance of sex in the short- and long-term effects of early life pain.


Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1882
Author(s):  
Ria van Dyke ◽  
Melanie Connor ◽  
Amy Miele

While veterinarians are instrumental to the welfare of calves (Bos taurus), limited knowledge exists concerning veterinary perceptions towards perioperative pain management in calves. As a part of a larger, nationwide study investigating the perceptions of veterinarians towards calf welfare, the current work sought to quantify veterinary perceptions towards perioperative pain management, including barriers to its use, and investigate demographic influences affecting those perceptions. An electronic mixed-methods survey was completed by 104 veterinarians registered with the Veterinary Council of New Zealand. The current work revealed that most veterinarians considered a multimodal approach as the most effective method for ameliorating perioperative pain in calves, rejected the practice of differential treatment based on developmental age, and perceived that postprocedural pain persists beyond 24 h for the majority of procedures included in the survey. Despite this, veterinarians identified certain barriers that may inhibit the provision of pain mitigation on-farm, including costs, inadequate recognition of pain, and ingrained farming practices. Certain demographic effects were found to influence perceptions towards perioperative pain management, including gender, the number of years since graduation, and species emphasis. Nevertheless, the current work demonstrated considerable support among veterinarians to improve pain management protocols during routine husbandry procedures. The asymmetries that exist between the current minimum provisions of perioperative pain management and veterinary perspectives suggest that substantive improvements are necessary in order to reconcile New Zealand’s existing regulatory regime with developments in scientific knowledge.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
L Cavazzana ◽  
M Errico ◽  
A Gimigliano ◽  
R Anniverno ◽  
L Bernardo ◽  
...  

Abstract Issue Many diseases show differences in incidence, symptoms, and severity between men and women, combined with a different response to therapies. There are some international experiences of health policies about Gender Medicine, but the practical realizations are few and, for the female sex, usually focused only on fertile age. Description of the problem A Milan hospital (ASST Fatebenefratelli Sacco) decided to dedicate one of its sites, with gynecological and pediatric vocation but also with an Internal Medicine Unit in within, entirely to women's health. The focus of this site is a holistic approach to women's health needs, both physiologic and pathologic. Realized without additional institutional funds, this project was designed between June and October 2019, started in December 2019 and is still ongoing. Results One of the first actions taken was to admit only women in the Internal Medicine Unit. The Unit is now entirely focused on dealing with most frequent female pathologies, in particular on autoimmune, vascular, endocrinology and nephrology conditions. The Mental Health Unit, already specialized in supporting pregnancy and new mothers, is going to activate a “Mother-Baby Unit” to support potential hospitalization issues. Among its major aims, the Occupational Medicine Unit supports female workers in managing maternity leave. New outpatient clinical paths have been planned to strengthen key moments of women's life: developmental age, fertile age, menopause, and senescence. Based on multi-professional teams, these programs are targeted toward age-specific needs and combine knowledge of disease epidemiology with sociological needs. To better face emerging issues, a path is activated for each area every month. Conclusions The birth of the first Italian hospital entirely dedicated to Gender Medicine allows care of women's health on a holistic perspective. This is, indeed, a key step in the general appraisal of Gender Medicine at the national and international levels. Key messages A gender hospital with a holistic approach to women’s health needs, both physiologic and pathologic, was borne in Milan. Integrated clinical paths have been activated to assist women in the key moments of their life (developmental age, fertile age, menopause, and senescence).


2011 ◽  
Vol 32 (S3) ◽  
pp. 307-309 ◽  
Author(s):  
Daria Riva ◽  
Arianna Usilla ◽  
Veronica Saletti ◽  
Sivia Esposito ◽  
Sara Bulgheroni

Development ◽  
1977 ◽  
Vol 41 (1) ◽  
pp. 79-92
Author(s):  
Rosita Smith ◽  
Anne McLaren

In normal mouse embryos developing in vivo, the first appearance of the blastocyst cavity was found to be associated more closely with developmental age, judged by cell number, than with chronological age, i.e. elapsed time since ovulation. When development was slowed by in vitro culture, formation of the blastocoele was delayed. However, cell number itself was not a critical factor, since the number of cells per embryo could be doubled or tripled or halved by experimental manipulation without substantially affecting the timing of blastocoele formation. Experiments in which one cell division was suppressed with cytochalasin-B, leading to tetraploidy, showed that the number of cell divisions since fertilization was also not critical. A possible role is suggested either for nucleocytoplasmic ratio, or for the number of nuclear or chromosomal divisions or DNA replications since fertilization, all of which increase during cleavage.


PEDIATRICS ◽  
1956 ◽  
Vol 17 (5) ◽  
pp. 656-656

The present generally accepted definition of a premature based on weight (a newborn weighing less than 2,500 gm.) has obvious limitations. The authors have pursued an interesting attempt to find physiologic indices of development which may distinguish the state of maturity. A series of neuromotor examinations is correlated with gestational period: visual perception, Moro reflex, manual grasping, prone behavior, swallow reflex, sucking reflex, sleeping habits, and capacity to regulate temperature. A group of 33 infants weighing 1,000 to 2,500 gm. were examined. The maximum of grasping-suck and prone-behavior reflexes appeared to develop simultaneously with the ability to suck, these accomplishments occurring in the thirty-fifth to thirty-seventh fetal week. The authors indicate that the degree of physiologic accomplishment correlates more closely with the gestational period than does the weight. It would seem that these observations should be extended to a much larger group of infants to determine the validity of the employment of physiologic indices rather than weight as a basis for judging maturity.


Gesture ◽  
2020 ◽  
Vol 19 (2-3) ◽  
pp. 299-334
Author(s):  
Arianna Bello ◽  
Silvia Stefanini ◽  
Pasquale Rinaldi ◽  
Daniela Onofrio ◽  
Virginia Volterra

Abstract In early communicative development, children with Down syndrome (DS) make extensive use of gestures to compensate for articulatory difficulties. Here, we analyzed the symbolic strategies that underlie this gesture production, compared to that used by typically developing children. Using the same picture-naming task, 79 representational gestures produced by 10 children with DS and 42 representational gestures produced by 10 typically developing children of comparable developmental age (3;1 vs. 2;9, respectively) were collected. The gestures were analyzed and classified according to four symbolic strategies. The two groups performed all of the strategies, with no significant differences for either choice or frequency of the strategies used. The item analysis highlighted that some photographs tended to elicit the use of the same strategy in both groups. These results indicate that similar symbolic strategies are active in children with DS as in typically developing children, which suggests interesting similarities in their symbolic development.


Development ◽  
1991 ◽  
Vol 113 (Supplement_1) ◽  
pp. 39-46 ◽  
Author(s):  
Liam Dolan ◽  
R. Scott Poethig

Leaf shape in cotton is regulated by the developmental age of the shoot and by several major genes that affect leaf lobing. The effect of these factors was investigated by allometric analysis, cell lineage analysis, and by studying the expression of the leaf shape mutation, Okra, in genetic mosaics. Allometric analysis of leaf growth suggests that leaf shape is determined during the initiation of the primordium rather than during the expansion phase of leaf growth. Clonal analysis demonstrates that both the rate and duration of cell division are fairly uniform throughout the leaf. Cells in the marginal region of the developing cotton leaf contribute more to the growth of the lamina than they do in tobacco. The Okra mutation acts early in the development of a leaf and appears to accentuate a developmental pattern that is also responsible for heteroblastic variation in leaf shape. The expression of this mutation in genetic mosaics demonstrates that its effect does not diffuse laterally within the leaf primordium.


2016 ◽  
Vol 6 (2) ◽  
pp. 1-29
Author(s):  
Claire Wiewauters ◽  
Kathleen Emmery

In dit artikel nemen we als focus de kwetsbare positie van het kind in de context rondom PAS (Parental Alienation Syndrome). We vertrekken vanuit een postmoderne visie op de werkelijkheid waarbij de betekenisgeving binnen een relationeel kader een belangrijke plaats inneemt. Ook de ontwikkelingsleeftijd van kinderen vergt onze aandacht. We toetsen ons conceptueel kader aan een analyse van 60 chatgesprekken van kinderen en jongeren met de hulplijn Awel over de scheiding van hun ouders en het leven in een samengesteld gezin. We formuleren een aantal concrete voorstellen die ervoor moeten zorgen dat de ontwikkeling en het welzijn van kinderen en jongeren zoveel mogelijk gewaarborgd blijft wanneer contactbreuk bij en na scheiding optreedt. Hiermee bieden we een antwoord op de draaglast en het isolement van kinderen. We houden een pleidooi om het actorschap van kinderen te verhogen. We pleiten voor meer samenwerking tussen de betrokkenen bij welzijn en justitie. Abstract :  This article focuses on the vulnerable position of the child in the context of PAS (Parental Alienation Syndrome).  Our starting point is a postmodern vision on reality in which meaning making plays an important role in relations.  We also pay attention to the developmental age of children. We test our conceptual framework with an analysis of 60 chat conversations of children and youngsters with the online service of the Flemish Child Helpline (‘Awel’) about the divorce of their parents and life in a newly composed family. We formulate several specific suggestions to make sure that the development and well‐being of children and youngsters is guaranteed as much as possible when contact is broken during and after the divorce. With this we offer a response to the burden and isolation of children. We make a plea to strengthen the agency of children and for more cooperation between the welfare work and legal actors that are involved.


1985 ◽  
Vol 30 (2) ◽  
pp. 119-129 ◽  
Author(s):  
B.J. Mcconville ◽  
R.T. Bruce

Considerable progress has been made in our understanding of depressive illnesses in childhood and adolescence, especially over the last several years. A number of major books on the subject have now appeared, along with a large number of individual papers. This paper attempts to summarize current knowledge, and indicates developmental, age-related and other issues which still require further study.


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