scholarly journals Attempt to Reduce Potentially Flammable Organic Solvents in Chemical Synthesis

2021 ◽  
pp. 16-18
Author(s):  
Takashiro Akitsu ◽  
Yuika Onami ◽  
Tetsundo Furuya
Keyword(s):  
Schiff Base ◽  
Organic Solvent ◽  
Organic Solvents ◽  
Synthesis Methods ◽  
Chemical Laboratory ◽  
X Ray ◽  
X Ray Crystallography ◽  
Research Article ◽  
Schiff Base Metal Complexes

A fire sometimes ignited an organic solvent in a chemical laboratory. A mechanochemical synthesis may be a good way to reduce the amount of organic solvents or without organic solvents compared to conventional synthesis in solutions. The solvent affected the product, namely solvent methanol acted as a ligand, although the quality of the data of X-ray crystallography is usually difficult to report in a strict research article in the case of our Azo-Schiff base metal complexes. Thus substitution of synthesis methods associated with potentially dangerous organic solvents may be possible depending on the application or purpose.

Synthesis, structural characterization and catalytic activity of chlororuthenium(II) complexes with substituted Schiff base/phosphine ancillary ligands

2020 ◽  
Vol 75 (9-10) ◽  
pp. 851-857
Author(s):  
Chong Chen ◽  
Fule Wu ◽  
Jiao Ji ◽  
Ai-Quan Jia ◽  
Qian-Feng Zhang
Keyword(s):  
Schiff Base ◽  
Catalytic Activity ◽  
Structural Characterization ◽  
Room Temperature ◽  
Molecular Structures ◽  
Cationic Complex ◽  
Neutral Complex ◽  
Ancillary Ligands ◽  
X Ray ◽  
X Ray Crystallography

AbstractTreatment of [(η6-p-cymene)RuCl2]2 with one equivalent of chlorodiphenylphosphine in tetrahydrofuran at reflux afforded a neutral complex [(η6-p-cymene)RuCl2(κ1-P-PPh2OH)] (1). Similarly, the reaction of [Ru(bpy)2Cl2·2H2O] (bpy = 2,2′-bipyridine) and chlorodiphenylphosphine in methanol gave a cationic complex [Ru(bpy)2Cl(κ1-P-PPh2OCH3)](PF6) (2), while treatment of [RuCl2(PPh3)3] with [2-(C5H4N)CH=N(CH2)2N(CH3)2] (L1) in tetrahydrofuran at room temperature afforded a ruthenium(II) complex [Ru(PPh3)Cl2(κ3-N,N,N-L1)] (3). Interaction of the chloro-bridged complex [Ru(CO)2Cl2]n with one equivalent of [Ph2P(o-C6H4)CH=N(CH2)2N(CH3)2] (L2) led to the isolation of [Ru(CO)Cl2(κ3-P,N,N-L2)] (4). The molecular structures of the ruthenium(II) complexes 1–4 have been determined by single-crystal X-ray crystallography. The properties of the ruthenium(II) complex 4 as a hydrogenation catalyst for acetophenone were also tested.

scholarly journals 4-vinylpyridine derivatives: Protonation, methylation and silver(I) coordination chemistry

2021 ◽  
pp. 174751982198965
Author(s):  
Guoqi Zhang
Keyword(s):  
Mass Spectrometry ◽  
Schiff Base ◽  
Coordination Chemistry ◽  
Elemental Analysis ◽  
Silver Complex ◽  
Spectroscopic Techniques ◽  
X Ray ◽  
X Ray Crystallography ◽  
Pyridine Moiety ◽  
New Compounds

( E)-4-[2-(Pyridin-4-yl)vinyl]benzaldehyde, containing both a 4-vinylpyridine and an aldehyde functionality, is utilized to develop new, highly conjugated chalcone compounds and a bis-Schiff base azine compound. The chalcone-containing compounds are further explored for their protonation, methylation and silver(I) coordination chemistry using the pyridine moiety. In parallel, a cyano-containing analogue, ( E)-4-[2-(pyridin-4-yl)vinyl]benzonitrile is also synthesized and studied for its silver(I) coordination chemistry. These new compounds are fully characterized by mass spectrometry, elemental analysis and spectroscopic techniques. The methylated product of ( E)-1-(9-anthryl)-3-{4-[2-(pyridin-4-yl)vinyl]phenyl}prop-2-en-1-one and a silver complex of ( E)-4-[2-(pyridin-4-yl)vinyl]benzonitrile are structurally determined by X-ray crystallography.

scholarly journals Structural Characterization of Heterodinuclear ZnII-LnIII Complexes (Ln = Pr, Nd) with a Ring-Contracted H2valdien-Derived Schiff Base Ligand

2021 ◽  
Author(s):  
Shabana Noor ◽  
Richard Goddard ◽  
Fehmeeda Khatoon ◽  
Sarvendra Kumar ◽  
Rüdiger W. Seidel
Keyword(s):  
Molecular Structure ◽  
Schiff Base ◽  
Structural Characterization ◽  
Schiff Base Ligand ◽  
Crystal And Molecular Structure ◽  
X Ray ◽  
X Ray Crystallography ◽  
Imidazoline Ring

AbstractSynthesis and structural characterization of two heterodinuclear ZnII-LnIII complexes with the formula [ZnLn(HL)(µ-OAc)(NO3)2(H2O)x(MeOH)1-x]NO3 · n H2O · n MeOH [Ln = Pr (1), Nd (2)] and the crystal and molecular structure of [ZnNd(HL)(µ-OAc)(NO3)2(H2O)] [ZnNd(HL)(OAc)(NO3)2(H2O)](NO3)2 · n H2O · n MeOH (3) are reported. The asymmetrical compartmental ligand (E)-2-(1-(2-((2-hydroxy-3-methoxybenzylidene)amino)-ethyl)imidazolidin-2-yl)-6-methoxyphenol (H2L) is formed from N1,N3-bis(3-methoxysalicylidene)diethylenetriamine (H2valdien) through intramolecular aminal formation, resulting in a peripheral imidazoline ring. The structures of 1–3 were revealed by X-ray crystallography. The smaller ZnII ion occupies the inner N2O2 compartment of the ligand, whereas the larger and more oxophilic LnIII ions are found in the outer O2O2’ site. Graphic Abstract Synthesis and structural characterization of two heterodinuclear ZnII-LnIII complexes (Ln = Pr, Nd) bearing an asymmetrical compartmental ligand formed in situ from N1,N3-bis(3-methoxysalicylidene)diethylenetriamine (H2valdien) through intramolecular aminal formation are reported.

Electrical property and Schottky behavior of a flexible Schiff-base compound: X-ray structure and stabilization of 1D water chain

2018 ◽  
Vol 20 (38) ◽  
pp. 24744-24749 ◽  
Author(s):  
Basudeb Dutta ◽  
Joydeep Datta ◽  
Suvendu Maity ◽  
Chittaranjan Sinha ◽  
Di Sun ◽  
...  
Keyword(s):  
Schiff Base ◽  
Electrical Property ◽  
Impedance Spectroscopy ◽  
Schottky Diode ◽  
X Ray ◽  
X Ray Crystallography ◽  
Water Chain ◽  
Schiff Base Compound ◽  
Base Compound

A flexible Schiff-base compound has been synthesized and structurally confirmed by X-ray crystallography. The compound behaves as a Schottky diode, as supported by the impedance spectroscopy.

scholarly journals Preparation of Nanoparticles Including Antisolvent Drugs by the Combination of Roll Milling and High-pressure Homogenization

2018 ◽  
Vol 14 (2) ◽  
pp. 143-147 ◽  
Author(s):  
Seitaro Kamiya ◽  
Maya Yamada ◽  
Miki Washino ◽  
Kenichiro Nakashima
Keyword(s):  
Particle Size ◽  
High Pressure ◽  
Organic Solvent ◽  
Organic Solvents ◽  
Peak Shift ◽  
Diffraction Peak ◽  
High Pressure Homogenization ◽  
X Ray Diffraction ◽  
X Ray ◽  
Wet Process

Description: Design methods of nanoparticle formulations are divided into break-down methods and build-up methods. The former is further divided into dry and wet processes. For drug nanoparticle preparations, the wet process is generally employed, and organic solvents are used in most formulations. Method: In this study, we investigate the preparation of nifedipine (IB) and griseofulvin (GF) nanoparticles without using organic solvent. Both IB and GF nanoparticles, with a mean particle size of approximately 50 nm, were prepared without organic solvent by employing a combination of roll milling and high-pressure homogenization. Result: The X-ray diffraction peak of the IB and GF samples prepared by roll milling was present at a position (2θ) identical to that of IB and GF crystals, indicating that no peak shift was induced by interaction with phospholipids. Conclusion: These findings demonstrate that most IB and GF nanoparticles exist as crystals in phospholipids.

Synthesis, characterization, crystal structure, electrochemical, solvatochromic and biological investigation of novel N4 and N3 type Cu(ii) Schiff base complexes

2017 ◽  
Vol 41 (21) ◽  
pp. 12554-12561 ◽  
Author(s):  
Akbar Azary ◽  
Abolfazl Bezaatpour ◽  
Saber Zahri ◽  
Mandana Amiri
Keyword(s):  
Crystal Structure ◽  
Schiff Base ◽  
Infrared Spectroscopy ◽  
Elemental Analysis ◽  
Schiff Base Complexes ◽  
Conductivity Measurements ◽  
Biological Investigation ◽  
X Ray ◽  
X Ray Crystallography

In the present study, three novel Cu(ii) Schiff base complexes were synthesized and characterized using infrared spectroscopy, elemental analysis, conductivity measurements and X-ray crystallography.

Synthesis, structure, and electrochemistry of cobalt(III) complexes with bis(benzoylacetone)ethylenediimine Schiff base

2002 ◽  
Vol 80 (9) ◽  
pp. 1196-1203 ◽  
Author(s):  
Mehdi Amirnasr ◽  
Rasoul Vafazadeh ◽  
Amir H Mahmoudkhani
Keyword(s):  
Schiff Base ◽  
Reduction Potential ◽  
Crystal And Molecular Structure ◽  
Acetonitrile Solution ◽  
Potential Range ◽  
Carbon Electrode ◽  
X Ray ◽  
X Ray Crystallography ◽  
H Nmr ◽  
C Nmr

A series of complexes of the type trans-[Co((BA)2en)(amine)2]ClO4 — where (BA)2en is the bis(benzoylacetone)ethylenediimine dianion and the amines are morpholine (mrpln) 1, aniline (aniln) 2, benzylamine (bzlan) 3, piperidine (pprdn) 4, p-toluidine (p-toldn) 5, and pyrrolidine (prldn) 6 — has been synthesized and characterized by elemental analysis, UV–vis, 1H NMR, and 13C NMR spectroscopy. The crystal and molecular structure of trans-[Co((BA)2en)(mrpln)2]ClO4 (1) has been determined by X-ray crystallography. The electrochemical reduction of these complexes at a glassy-carbon electrode, in the potential range of 0.5 to –2.0 V (vs. Ag/AgCl), in acetonitrile solution, indicates that the first reduction potential of Co(III/II) is irreversible, which is accompanied by the dissociation of the axial amine–cobalt bonds. This potential is dependent on the pKa of the axial amines. The second reduction potential of Co(II/I) shows reversible behavior and is also independent of the axial amine pKa. These results indicate the loss of the axial amines in the first redox process and the involvement of a four-coordinate species in the second redox step.Key words: Schiff base, cobalt(III), axial amine, electrochemical properties, crystal structure.

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