scholarly journals Nontuberculous Mycobacteria in Humans, Animals, and Water in Zambia: A Systematic Review

2021 ◽  
Vol 2 ◽  
Author(s):  
Mildred Zulu ◽  
Ngula Monde ◽  
Panji Nkhoma ◽  
Sydney Malama ◽  
Musso Munyeme
Keyword(s):  
Public Health ◽  
Systematic Review ◽  
Literature Search ◽  
Nontuberculous Mycobacteria ◽  
Scientific Evidence ◽  
Health Impact ◽  
Multidrug Resistant ◽  
Public Health Importance ◽  
Kafue Lechwe ◽  
Acquired Immunodeficiency

Nontuberculous mycobacteria (NTM) are environmental opportunistic pathogens of humans and animals that are emerging with a serious public health impact particularly in individuals with Acquired Immunodeficiency Syndromes. Recent scientific evidence is shifting from NTMs being known as traditional environmental organisms to serious pathogenic organisms in both animals and humans. In humans, factors attributable to this rise have been linked mainly to Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome pandemic. In recent years there has been an increase in multidrug resistant Tuberculosis in Zambia and it is thought that NTMs could possibly be the cause. This study was therefore formulated to review available information on the prevalence of NTM in humans, animals and the environment, species distribution, zoonotic potential and public health importance in Zambia. This review was conducted in accordance with PRISMA guidelines. A literature search was done in PubMed and Google scholar using predefined search terms such as ‘nontuberculous mycobacteria’, ‘atypical mycobacteria’, ‘mycobacteria other than mycobacterium tuberculosis’ and ‘Zambia’, in combination with Boolean operators (AND, OR). This particular systematic review draws findings based on literature search between 2000 and 2020. Through literature search 243 papers were identified, 23 duplicates were identified and removed and 206 articles were excluded as they did not meet the inclusion criteria. The full text of the remaining 14 articles were considered for this review. The overall prevalence of NTM in humans was 24.39%, in water 21.5%, in animals 16.05% of which the prevalence in cattle was 14.81% and Kafue Lechwe 1.23%. Mycobacterium intracellulare was the most common isolated nontuberculous mycobacteria in humans and cattle while Mycobacterium gordonae was the most common in water, and Mycobacterium stomatepiae sp Nov in Kafue Lechwe. Nontuberculous mycobacteria are an emerging public health threat in Zambia both in humans and animals and this calls for the need for molecular information on the zoonotic transmission of nontuberculous mycobacteria. Increased awareness of nontuberculous mycobacteria diseases among clinicians and laboratory personnel is crucial for patient management and an essential step for facilitating the identification of nontuberculous mycobacteria species in laboratories.

scholarly journals Anisakis sensitization in different population groups and public health impact: A systematic review

PLoS ONE ◽  
2018 ◽  
Vol 13 (9) ◽  
pp. e0203671 ◽  
Author(s):  
Walter Mazzucco ◽  
Daniele Domenico Raia ◽  
Claudia Marotta ◽  
Antonella Costa ◽  
Vincenzo Ferrantelli ◽  
...  
Keyword(s):  
Public Health ◽  
Systematic Review ◽  
Health Impact ◽  
Public Health Impact ◽  
Population Groups

scholarly journals The Pregnancy and Birth to 24 Months Project: a series of systematic reviews on diet and health

2019 ◽  
Vol 109 (Supplement_1) ◽  
pp. 685S-697S ◽  
Author(s):  
Eve E Stoody ◽  
Joanne M Spahn ◽  
Kellie O Casavale
Keyword(s):  
Public Health ◽  
Systematic Review ◽  
Dietary Intake ◽  
Systematic Reviews ◽  
Feeding Practices ◽  
The Body ◽  
Feeding Strategies ◽  
Public Health Importance ◽  
Review Team ◽  
Pregnancy And Birth

ABSTRACTNutrition exposures during the earliest stages of life are integral to growth and development and may continue to affect health through adulthood. The purpose of the Pregnancy and Birth to 24 Months (P/B-24) Project was to conduct a series of systematic reviews on diet and health for women who are pregnant and for infants and toddlers from birth to 24 mo of age. The P/B-24 Project was a joint initiative led by the USDA and the US Department of Health and Human Services. The USDA's Nutrition Evidence Systematic Review team, previously known as the Nutrition Evidence Library, carried out the series of systematic reviews in collaboration with programmatic and scientific experts. Systematic review questions were prioritized based on federal policy, program, or guidance needs, potential to support the development of healthy dietary intake, and public health importance. Systematic reviews were conducted on specific topics related to dietary intake before and during pregnancy, infant milk feeding practices, complementary feeding, flavor exposures, and infant/toddler feeding practices. Across the reviews, relationships were observed between P/B-24 diet exposures and a variety of outcomes of public health importance. Evidence showed links between dietary intake before and during pregnancy, during the period of human milk or infant formula feeding, and through introduction of complementary foods and beverages and health outcomes. Additionally, the reviews on flavor exposure and infant/toddler feeding practices highlight the importance of maternal diet during pregnancy and lactation and caregiver feeding strategies and practices. Systematic reviews are an important tool to inform our understanding of the body of evidence related to diet and health, and scientists can use the P/B-24 Project reviews to continue to advance research in these areas.

scholarly journals Environmental Contaminants Exposure and Preterm Birth: A Systematic Review

Toxics ◽  
2019 ◽  
Vol 7 (1) ◽  
pp. 11 ◽  
Author(s):  
Maria Porpora ◽  
Ilaria Piacenti ◽  
Sara Scaramuzzino ◽  
Luisa Masciullo ◽  
Francesco Rech ◽  
...  
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Systematic Review ◽  
Preterm Birth ◽  
Neonatal Period ◽  
Environmental Contaminants ◽  
Health Impact ◽  
Environmental Toxicants ◽  
Significant Public Health ◽  
Clinical Measures

Preterm birth is an obstetric condition associated with a high risk of infant mortality and morbidities in both the neonatal period and later in life, which has also a significant public health impact because it carries an important societal economic burden. As in many cases the etiology is unknown, it is important to identify environmental factors that may be involved in the occurrence of this condition. In this review, we report all the studies published in PubMed and Scopus databases from January 1992 to January 2019, accessible as full-text articles, written in English, including clinical studies, original studies, and reviews. We excluded articles not written in English, duplicates, considering inappropriate populations and/or exposures or irrelevant outcomes and patients with known risk factors for preterm birth (PTB). The aim of this article is to identify and summarize the studies that examine environmental toxicants exposure associated with preterm birth. This knowledge will strengthen the possibility to develop strategies to reduce the exposure to these toxicants and apply clinical measures for preterm birth prevention.

scholarly journals Patient safety incidents in ambulatory care in Germany

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
M Geraedts ◽  
S Krause ◽  
M Schneider ◽  
J Leinert ◽  
W de Cruppé
Keyword(s):  
Public Health ◽  
Patient Safety ◽  
Total Population ◽  
Health Impact ◽  
Computer Assisted ◽  
Public Health Importance ◽  
Cross Sectional ◽  
Survey Tool ◽  
Outpatient Sector ◽  
Patient Safety Incidents

Abstract Background In contrast to the inpatient sector, reliable data on the epidemiology and public health impact of patient safety incidents (PSI) are hardly found in the outpatient sector. Thus, this study focusses on the incidence of PSI; the distribution among the various specialist groups; the harmful consequences; the causes and how affected patients deal with PSI in Germany. Methods We conducted a cross-sectional study using a newly developed computer-assisted-telephone-interview survey tool. Based on random telephone numbers, citizens >39 years were asked to report whether they had experienced a PSI in the last year or since their 40th birthday; whereby the PSI happened, what consequences the PSI had for them and if they reported the PSI back to their physician. We performed descriptive and multivariate analyses and extrapolated the results to the total population >39 years in Germany. Results 10037 citizens were surveyed (response rate 13%): 8841 had an outpatient visit last year, of whom 1570 (18%) had experienced at least one PSI. In total, 2832 PSI were reported. General practitioners caused 43% of PSI. Among specialists (54%), most PSI were found among orthopedists (15%) and internists (9%) and arose in connection with anamnesis and clinical examination (61%) as well as drug prescriptions (15%). 72% of the PSI caused health related harm. The most frequent harm was a deterioration in health (23%) and persistent pain (22%). 54% of those affected described the harm as severe or very severe. 27% considered doctors’ stress and lack of time or poor communication (18%) as causes for PSI. 32% of PSI were reported back to the treating physician. Discussion Extrapolated to the total population >39 years in Germany (47.2 million), an incidence of 12 million PSI per year must be expected with around 6.6 million affected outpatients. Thus, PSI in the outpatient sector are of immense public health importance in Germany. Key messages Patient safety incidents (PSI) often happen in the German outpatient sector. Outpatient PSI can also be accompanied by severe harm for patients.

scholarly journals Norovirus outbreaks: a systematic review of commonly implicated transmission routes and vehicles

2013 ◽  
Vol 141 (8) ◽  
pp. 1563-1571 ◽  
Author(s):  
E. J. BITLER ◽  
J. E. MATTHEWS ◽  
B. W. DICKEY ◽  
J. N. S. EISENBERG ◽  
J. S. LEON
Keyword(s):  
Public Health ◽  
Systematic Review ◽  
Environmental Conditions ◽  
Attack Rate ◽  
Strain Distribution ◽  
Regulatory Action ◽  
Recreational Water ◽  
Transmission Route ◽  
Public Health Importance ◽  
Great Public Health

SUMMARYCausal mechanisms of norovirus outbreaks are often not revealed. Understanding the transmission route (e.g. foodborne, waterborne, or environmental) and vehicle (e.g. shellfish or recreational water) of a norovirus outbreak, however, is of great public health importance; this information can facilitate interventions for an ongoing outbreak and regulatory action to limit future outbreaks. Towards this goal, we conducted a systematic review to examine whether published outbreak information was associated with the implicated transmission route or vehicle. Genogroup distribution was associated with transmission route and food vehicle, but attack rate and the presence of GII.4 strain were not associated with transmission route, food vehicle, or water vehicle. Attack rate, genogroup distribution, and GII.4 strain distribution also varied by other outbreak characteristics (e.g. setting, season, hemisphere). These relationships suggest that different genogroups exploit different environmental conditions and thereby can be used to predict the likelihood of various transmission routes or vehicles.

scholarly journals Rodent-Related Zoonotic Pathogens at the Human–Animal–Environment Interface in Qatar: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 18 (11) ◽  
pp. 5928
Author(s):  
Md Mazharul Islam ◽  
Elmoubashar Farag ◽  
Ahmad Mahmoudi ◽  
Mohammad Mahmudul Hassan ◽  
Ehsan Mostafavi ◽  
...  
Keyword(s):  
Public Health ◽  
Systematic Review ◽  
Meta Analysis ◽  
Significant Heterogeneity ◽  
Salmonella Spp ◽  
Public Health Importance ◽  
Screening Process ◽  
Zoonotic Pathogens ◽  
Terrestrial Mammals ◽  
Human Animal

Rodents are one of the most diversified terrestrial mammals, and they perform several beneficial activities in nature. These animals are also important as carriers of many pathogens with public health importance. The current systematic review was conducted to formulate a true depiction of rodent-related zoonoses in Qatar. Following systematic searches on PubMed, Scopus, Science Direct, and Web of Science and a screening process, a total of 94 published articles were selected and studied. The studied articles reported 23 rodent-related zoonotic pathogens that include nine bacterial, eleven parasitic, and three viral pathogens, from which the frequently reported pathogens were Mycobacterium tuberculosis (32 reports), Escherichia coli (23), and Salmonella spp. (16). The possible pathway of entry of the rodent-borne pathogens can be the land port, seaports, and airport of Qatar through carrier humans and animals, contaminated food, and agricultural products. The pathogens can be conserved internally by rodents, pets, and livestock; by agricultural production systems; and by food marketing chains. The overall estimated pooled prevalence of the pathogens among the human population was 4.27% (95%CI: 4.03–4.51%; p < 0.001) with significant heterogeneity (I2 = 99.50%). The top three highest prevalent pathogens were M.tuberculosis (30.90%; 22.75–39.04%; p < 0.001; I2 = 99.70%) followed by Toxoplasma gondii (21.93%; 6.23–37.61%; p < 0.001; I2 = 99.30%) and hepatitis E virus (18.29%; 11.72–24.86%; p < 0.001; I2 = 96.70%). However, there is a knowledge gap about the listed pathogens regarding the occurrence, transmission pathways, and rodent role in transmission dynamics at the human–animal–environment interface in Qatar. Further studies are required to explore the role of rodents in spreading zoonotic pathogens through the One Health framework, consisting of zoologists, ecologists, microbiologists, entomologists, veterinarians, and public health experts in this country.

scholarly journals Emerging and re-emerging human infectious diseases: A systematic review of the role of wild animals with a focus on public health impact

2020 ◽  
Vol 13 (3) ◽  
pp. 99 ◽  
Author(s):  
MarliC Cupertino ◽  
MichelyB Resende ◽  
NicholasAJ Mayer ◽  
LorendaneM Carvalho ◽  
Rodrigo Siqueira-Batista
Keyword(s):  
Public Health ◽  
Systematic Review ◽  
Infectious Diseases ◽  
Health Impact ◽  
Public Health Impact ◽  
Wild Animals

scholarly journals Detection of Rift Valley Fever Virus Interepidemic Activity in Lower Moshi area of Kilimanjaro Region, North Eastern Tanzania: A Community Survey

2021 ◽  
Author(s):  
Jaffu Chilongola ◽  
Medard Kumalija ◽  
Rule Budodo ◽  
Pius Horumpende ◽  
Sixbert Mkumbaye ◽  
...  
Keyword(s):  
Public Health ◽  
Infection Rate ◽  
Rift Valley ◽  
Rift Valley Fever ◽  
Rift Valley Fever Virus ◽  
Health Impact ◽  
Fever Virus ◽  
Public Health Importance ◽  
Valley Fever ◽  
Significant Difference

Abstract Background: Rift Valley fever virus (RVFV) is a zoonotic arbovirus of public health impact infecting livestock, wildlife, and humans mainly in Africa and other parts of the world. Despite its public health importance, mechanisms of RVFV maintenance during inter-epidemic (IEPS) periods and potentially spread to new areas remain unclear.We aimed to comparatively examine exposure to RVFV and RVFV infection among humans, goats and mosquitoes in an agro-pastoral community in Lower Moshi area of Moshi rural district.Results:Results show that the male gender was related to RVFV seropositivity (χ2 = 5.351; p=0.030). Being 50 years and above was related to seropositivity (χ2=14.430; p=0.006) whereas bed net use, larger numbers of persons living in the same house (>7 persons) and RVFV seropositivity in goats were related to higher seropositivity to RVFV among humans (χ2=6.003; p=0.021, χ2=23.213; p=0.000 and 27.053; p=0.000), respectively.RVFV antibody concentrations were only marginally higher in humans without statistically significant difference [t (112) =0.526; p=0.60)]. By the use of RT-qPCR, goats exhibited the highest RVFV infection rate of 4.1%, followed by humans (2.6%), Aedes spp(2.3%), and Culex spp(1.5%). Conclusions: In the absence of RVFV infection data in areas nearby the study site, our findings suggest Lower Moshi area as a potential hotspot for RVF, posing the danger of being a source of RVFV spread to other areas. Goats had the highest infection rate, suggesting goats as important hosts in the virus maintenance during IEPs. We recommend the design and implementation of strategies that will warrant effective active surveillance of RVF through the identification of RVF hotspots for targeted control of RVF.

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