scholarly journals Beyond the Visual Acuity: Assessing the Visual Function in mCNV Patients After Anti-VEGF Treatment

2021 ◽  
Vol 8 ◽  
Author(s):  
Songshan Li ◽  
Limei Sun ◽  
Xiujuan Zhao ◽  
Zhaotian Zhang ◽  
Xiaoling Luo ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Visual Function ◽  
Statistical Significance ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Subscale Score ◽  
Anti Vegf ◽  
Significant Difference ◽  
Before And After ◽  
Ranibizumab Treatment

Purpose: To investigate visual function and vision-related quality of life (VR-QoL) changes in patients with myopic choroidal neovascularization (mCNV) after ranibizumab treatment.Methods: Quantitatively evaluate the objective tests of visual function (visual acuity, microperimetry, and metamorphopsia by m-Charts) before and after 3+prn (pro re neta) ranibizumab treatment for 1 year. The National Eye Institute 25-Item Visual Function Questionnaire (VFQ-25) was performed to evaluate the VR-QoL.Results: A total of 57 eyes of 57 patients were included in this study. The median average metamorphopsia score was 0.65 before treatment and improved to 0.45 after treatment (p = 0.0003). There was also a significant difference in the average threshold, macular integrity, and proportion of patients with stable fixation by the microperimetry (p < 0.000, p < 0.0001, and p = 0.03, respectively). After treatment, the VR-QoL composite, general vision subscale, and vision-related mental health subscale score were increased with borderline or statistical significance (p = 0.088, p = 0.0038, and p = 0.012, respectively). Subgroup analysis demonstrated parallel improvement of the VR-QoL score, metamorphopsia, average macular threshold, and fixation stability in patients with or without visual acuity increase. By multiple linear regression analysis, the VFQ-25 score after anti-VEGF treatment was only associated with the baseline VFQ-25 score and macular integrity. Improvements in the VFQ-25 score were only associated with changes in the metamorphopsia score.Conclusions: Integral lifting in several aspects of visual function was observed in mCNV after ranibizumab treatment. Macular integrity and metamorphopsia, but not visual acuity, were associated with VR-QoL.

STUDY CLINICAL FEATURE AND RESULT OF TREATMENT PHACOMORPHIC GLAUCOMA

2015 ◽  
pp. 71-75
Author(s):  
Van Nam Phan ◽  
Ba Ken Tran
Keyword(s):  
Visual Acuity ◽  
Intraocular Pressure ◽  
Statistical Significance ◽  
Corneal Edema ◽  
Clinical Feature ◽  
Anterior Chamber Angle ◽  
Male Population ◽  
Significant Difference ◽  
Operative Complications ◽  
Before And After

Purpose: Study clinical feature of phacomorphic glaucoma. To evaluate the result of treatment phacomorphic glaucoma. Method: The retrospective, interventional study on 36 cases with phacomorphic glaucoma who underwent treated at Hue Central Hospital from 6/2010 to 6/2011. Standard of research: visual, IOP, before and after surgery, accompanying lesions and post-operative complications. The surgery is considered successful when postoperative IOP less than 21 mmHg. Results: Age 50-59 presented 30.5 percent, ≥ 60 presented 91.7 percent. There was a slight female preponderance (66.7%) compared to the male population (33.3%) which implies a statistically marginally significant difference. However there was no statistical significance difference when compared by the two subgroups. Patient in country presented 61,1% and city presented 38,9%. The duration between the onset of pain and surgery from 0 to < 5 days (77.8%), from 6 to 10 (16.7%) and >10 days presented 5.5%. The preoperative intraocular pressure 35 to 45mmHg (47.2%), 46-55 (30.6%), 56-65 (13.9%) and more than 65 presented 8.3%. The visual acuity preoperation less than 1metre count finger (94.5%), less than 3 metre count finger presented 5.5%. Close anterior chamber angle presented 80.6% and shallow was presented 19.4%. Corneal edema presented 100%, iritis presented 94.4%, dilated pupil larger 5mm presented 83.3%, Synchynea iris and cataract presented 72.2%. ECCE, implantation IOL combined trabeculectomy presented 11.1%, Phaco, implantation IOL combined trabeculectomy presented 69,5%, ECCE implantation IOL presented 5.6%, Phaco, implantation IOL presented 13.8%. Postoperative visual acuity from 1/10 to 5/10 presented 72.2%, no case have VA larger than 5/10. Postoperative 3 months VA 1/10 to 5/10 presented 72.2%, larger VA 5/10 presented 8.3%. Postoperative 3 months intraocular pressure ≤ 21mmHg presented 91.7%, 22 to 24mmHg presented 8.3%, no case have IOP ≥25mmHg. Postoperative edema presented 58.3%, iritis presented 58.3%. Key words: phacomorphic Glaucoma

scholarly journals Characteristics of fixation patterns and their relationship with visual function of patients with idiopathic macular holes after vitrectomy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yuyan Liu ◽  
Ying Wang ◽  
Yi Dong ◽  
Dongqing Liang ◽  
Shiyong Xie ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Visual Function ◽  
Retrospective Case ◽  
Integrity Assessment ◽  
Fixation Location ◽  
Macular Holes ◽  
Significant Difference ◽  
Before And After ◽  
Fixation Locations ◽  
Idiopathic Macular Holes

AbstractTo analyze the relationships between the fixation location and the visual function of idiopathic macular hole (IMH) patients with macular integrity assessment (MAIA) examination preoperatively and 3 months postoperatively. This was a retrospective case analysis. Forty-three eyes of 43 patients diagnosed with IMH were included in this study. The best corrected visual acuity (BCVA) assessments, optical coherence tomography (OCT) and MAIA examinations were performed before surgery and 1 week, 1 month and 3 months after surgery. The relationships between MAIA parameters and visual acuity were assessed by correlation analysis. Grouping by fixation location with the foveola (2°) as the centre, the locations could be divided into five groups, including foveolar, temporal, nasal, inferior and superior fixation. The mean macular sensitivity (MMS) of the macular area was correlated with the BCVA in the IMH patients before and 3 months after surgery (before surgery P = 0.00, after surgery P = 0.00). The MMS could be used as a good indicator for evaluating visual function in IMH patients. There was a significant difference in fixation location before and after the operation (P = 0.01). The preoperative fixation location of IMH patients was mainly in the superior area, while postoperatively moved to the foveola and nasal areas. Paying attention to the changes of fixation locations in IMH patients may provide new clues for further improving postoperative visual function.

scholarly journals Efektifitas Pelatihan Emotional Intelligence untuk Meningkatkan Resiliensi pada Siswi SMP yang Melakukan Self Injury

2020 ◽  
Vol 5 (2) ◽  
pp. 114-131
Author(s):  
Lebda Katodhia ◽  
Frikson C. Sinambela
Keyword(s):  
Emotional Intelligence ◽  
Single Case ◽  
Statistical Significance ◽  
Linear Regression Analysis ◽  
School Students ◽  
Self Injury ◽  
Significant Difference ◽  
Before And After ◽  
Emotional Intelligence Training

The rise of the case of middle school students who commit acts of self-injury creates new problems in education. The cause is a lack of resilience in self. When this condition is left constantly, it will have an impact on psychological problems. This study aims to understand the effectiveness of emotional intelligence training in enhancing students’ resilience in SMP X Surabaya. The method used in this experimental study is a single case experimental design. There were 19 female students have been doing self-injury such as slashing their hands. First, The Resilience Scale is used to assess students’ resilience and The Assessing Emotions Scale Mayor-Salovey is used for assessing emotional intelligence. Second, the result analyzed with Paired Sample T-test. Third, Linear Regression Analysis conducted to examine the effect the training on students’ resiliency. In the follow-up stage, the data analyzed using a Wilcoxon Signed Rank. The emotional intelligence training gave in 4 sessions within 2 days. Besides, in the follow-up stage, participants are interviewed. The result shows statistical significance of 0.009 (p < 0.05). It conveys there is a significant difference in students' resilience levels before and after the training. The significant results of the training lasted until the follow-up one week after the training. The existence of emotional intelligence makes the participants more persistent and resilient in dealing with daily problems so that the participants will not repeat their self-harming behavior.

scholarly journals PERBEDAAN KUALITAS HIDUP PASIEN USIA LANJUT SEBELUM DAN SETELAH OPERASI KATARAK

2020 ◽  
Vol 4 (1) ◽  
pp. 63-68
Author(s):  
Adelia Lisnawati
Keyword(s):  
Quality Of Life ◽  
Visual Acuity ◽  
Elderly Patients ◽  
Cataract Surgery ◽  
Visual Function ◽  
Social Life ◽  
Significant Difference ◽  
Before And After ◽  
Eye Clinic

Cataract is a condition when the lens become cloudy and often occurs in elderly patients. Cataract is the leading cause of visual impairment and blindness in the world. Cataract can reduce productivity and social life, that will decrease the quality of life in elderly patients. It also reduces the visual acuity leading to decreasing visual function and the quality of life. This disease can change physical, cognitive and psychosocial life. This study aimed to analyze the difference of quality of life in elderly patients before and after cataract surgery at SMEC eye clinic in Samarinda. This study was observational analytic study. Data were taken from interview the patients with visual function questionnaire 14 (VFQ 14) and from the medical record of SMEC eye clinic in Samarinda. The results showed a significant difference of quality of life in elderly patients before and after cataract surgery (p = 0,000) with the mean score of quality of life before surgery (x̅= 63,65) was lower than after cataract surgery (x̅= 95,35) and there was significant improvement of the visual acuity after cataract surgery (p = 0,000). Based on these results it can be concluded that there were difference of quality of life in elderly patients before and after cataract surgery.

State Recreational Marijuana Laws and Dispensaries: Chronic School Absenteeism in Washington State

2021 ◽  
Vol 8 (4) ◽  
Author(s):  
Maxim Gakh ◽  
Courtney Coughenour ◽  
Brooke Kleven ◽  
Brian Labus
Keyword(s):  
Social Factors ◽  
Statistical Significance ◽  
Secondary Analysis ◽  
Risk Groups ◽  
Washington State ◽  
School Absenteeism ◽  
Chronic Absenteeism ◽  
Significant Difference ◽  
Before And After ◽  
Recreational Marijuana

Objective: Whereas states continue to experiment with liberalized marijuana laws, how these laws impact health, education, and social factors is not yet fully understood. In this study, we examined whether chronic school absenteeism rates changed in Washington State in the presence of recreational marijuana dispensaries pursuant to implementation of the state’s recreational marijuana laws. Methods: We conducted a secondary analysis using school district chronic absenteeism rates before and after the presence of recreational dispensaries. Results: The results of the independent samples t-test showed no statistically significant difference in chronic absenteeism rates among districts with or without recreational marijuana dispensaries. Conclusions: The finding of no statistical significance for chronic absenteeism in districts with and without recreational dispensaries – a pattern that largely persisted among at-risk groups – supports that the presence of recreational marijuana dispensaries seems neither to exacerbate nor improve chronic school absenteeism rates. This finding is important for policymakers, practitioners, and researchers trying to understand the changing marijuana legal landscape.

scholarly journals Faktor-Faktor yang Mempengaruhi Keberkesanan Amali Kerja Kayu dari Perspektif Pelajar Sekolah Menengah Vokasional di Provinsi Acheh

2017 ◽  
Vol 9 (1-5) ◽  
Author(s):  
Lailan Fachrah ◽  
Nor Azlina Hasbullah ◽  
Ashah Ab Rahman
Keyword(s):  
Linear Regression Analysis ◽  
Demographic Factors ◽  
Multiple Linear Regression Analysis ◽  
Vocational Schools ◽  
Student Interest ◽  
Security Issues ◽  
Equipment Safety ◽  
Significant Difference ◽  
Hands On ◽  
Stepwise Method

This study aims to identify factors that influence the effectiveness of practical woodworking and determine the effectiveness of practical woodworking from the perspective of students of secondary vocational schools in the province of Aceh. Factors studied were the workshop equipment, safety workshops, teaching skills, the workshop environment and student interest. This study was designed to investigate the significant differences concerning factors woodworking practical effectiveness based on demographic factors. A total of 130 respondents were randomly selected from six vocational schools in the province of Aceh. The instrument consists of a set of questionnaire consisting of 49 items and distributed to second level students. Data analysis using the two types of statistics, namely descriptive statistics and statistical inference. The results showed no significant difference between factors woodworking practical effectiveness based on demographic factors except the income level of parents and the parents of the respondents work. The results of multiple linear regression analysis stepwise method found that only four factors (environmental factors workshops, the students interest, the skills of teachers and workshop equipment factors) that affect the practical effectiveness of woodworking with the correlation coefficient R = 0.779. This shows there is a significant effect of the four factors, the effectiveness of practical woodworking, accounting for 60.6% (R2 = 0.606) changes in the variance in effectiveness of hands-on woodworking, and between the four factors, the workshop environment is the factor that most influences the effectiveness practical woodworking by contributing 43.3% (R2 = 0.433) of the variance in effectiveness of practical woodworking. The main implication of this study is the need for attention from the authorities to be more serious in efforts to improve the facilities and infrastructure in the workshop as well as security issues in practical workshops so that the effectiveness of the woodwork to be more robust.

scholarly journals The Effects of Patients' and Care-Givers' Knowledge, Attitude, & Practice (KAP) on Quality of Life Among Thalassemia Major Patients' in Damascus-Syrian Arab Republic

2018 ◽  
Vol 14 (12) ◽  
pp. 308
Author(s):  
Yaser Adnan Abo Jeesh ◽  
Magda El-hadi Ahmad Yousif ◽  
Moauya Al-Balal Al-Haboub
Keyword(s):  
Quality Of Life ◽  
Statistical Significance ◽  
Thalassemia Major ◽  
Cross Sectional ◽  
Attitudes And Practices ◽  
Teaching Guide ◽  
Care Givers ◽  
Significant Difference ◽  
Before And After

Background: Thalassemia is the most common autosomal abnormality in Syria. Its complications have an important effect on education; time off school; sport; difference from friends/ siblings; social interactions; and stigmatization. Knowledge of factors associated with quality of life in thalassemia patients is necessary for forming appropriate clinical programs, social support, and improving treatment outcomes. Purpose: The study was to assess the effects of Patients' and Care-givers' Knowledge, Attitude, & Practice (KAP) with Quality of Life among Thalassemia Major Patients' in Syria. Methods: Cross-sectional descriptive analytical design was conducted at the national thalassemia center in Damascus. WHOQOL-BREF and a questionnaire developed by the researcher were used to measure the participants’ knowledge, attitudes and practices of thalassemia. Results: Total of 238 thalassemia patients participated in the study. A statistical significance was found regarding improvement of skill and knowledge scores among caregivers and thalassemia patients before and after receiving the teaching guide from 12.52±1.77 to 14.07±1.01, t=11.447, p=0.000 and from 34.12±4.50 to 37.43±4.61, t=-8.58, p= .000 respectively. Stigmatization was significantly noticed among families caring for thalassemic patients. There were a significant differences in the mean score regarding nutritional status before and after teaching guide paired t test= 12.11, p= 0.000. A statistical significance was found in females regarding social domain p=0.04. However, mean scores for overall quality of life were better in females rather than males, but these mean scores were statistically insignificant p>0.05. A statistical significant difference in ferritin levels and patient’s age was found. Results also revealed that no statistical significant differences was observed between overall quality of life of the four domains in relation to the two treatment groups (subcutaneous vs oral) and age groups. Conclusion: Thalassemia is a socio-economic problem. The most efficient way to reduce risks of having affected patients is by increasing the knowledge through training of parents regarding the disease. Our findings highlighted that there was lack in patients’ knowledge and skills regarding the disease, but a remarkable improvement in both knowledge and performance was found after patients received the teaching guide, which lead to an increase in overall patient's quality of life.

scholarly journals PENGARUH GAYA HIDUP, SIKAP UANG, NILAI PRIBADI, STIMULASI PEMASARAN TERHADAP KEPUTUSAN PEMBELIAN TERHADAP SMARTPHONE ANDROID (Studi Kasus Mahasiswa Muhammadiyah Stikes Banjarmasin)

2019 ◽  
Vol 6 (1) ◽  
pp. 26
Author(s):  
Arina Putri ◽  
Nuril Huda
Keyword(s):  
Significant Relationship ◽  
Personal Values ◽  
Linear Regression Analysis ◽  
Multiple Linear Regression Analysis ◽  
Purchase Decision ◽  
Decision Variables ◽  
Analysis Technique ◽  
Significant Difference ◽  
Money Attitude ◽  
Strongly Agree

<p><em>This study aims to identify and analyze the influence of lifestyle variables (X1), money attitude (X2), personal values (X3), marketing stimulation (X4) on purchase decisions (Y).</em></p><p><em>Methods This study uses qualitative research by distributing questionnaires to students stikes muhammadiyah Banjarmasin ever using smartphones as much as 157 respondents. Using variable measurement technique kiteria interval scale from strongly agree to strongly disagree, with weights from 1 - 10. To determine the effect of variable X to variable Y using multiple linear regression analysis technique.</em></p><p><em>Results of this study conclude that (1) There is a significant difference between lifestyle variables to variable purchase decision. (2) There is a significant relationship between the variables attitude toward money purchase decision variables. (3) There is a significant relationship between the variables of personal values to the variable purchase decision. (4) There is no significant relationship between the variables of marketing stimulation to variable purchase decision.</em></p>

scholarly journals Cytotoxicity of three-dimensional paper-based models from a three-dimensional paper-based printer

NEMESIS ◽  
2018 ◽  
Vol 3 (1) ◽  
pp. 15 ◽  
Author(s):  
Marcin Kozakiewicz ◽  
Piotr Szymor ◽  
Raphael Olszewski
Keyword(s):  
Operating Room ◽  
Dermal Fibroblast ◽  
Statistical Significance ◽  
Three Dimensional ◽  
Dermal Fibroblasts ◽  
Tissue Adhesive ◽  
Biological Behaviour ◽  
Sterilization Method ◽  
Significant Difference ◽  
Before And After

Objective: Our study aimed to determine the possibility of using models created with a low-cost, paper based 3D printer in an operating room. Therefore influence of different methods of sterilization on models was tested and cytotoxicity of generated models was determined. Material and methods: 30 cuboids divided into three groups were used for verification of shape stability after sterilization. Each group was sterilized either with: Ethylene oxide in temperature 55˚C, Hydrogen peroxide gas plasma in temperature 60˚C or Gamma irradiation at 21˚C, 25kGy. Each cuboid was measured using calliper three times before and three times after sterilization. Results were analysed statistically in Statgraphics Plus. Statistical significance was determined as p< 0.05. Sixty cylinders divided into six groups were used for cytotoxicity tests. Three of those groups were covered before sterilization with 2-octyl-cyanoacrylate. Each group was sterilized with one of the previously described methods. Cytotoxicity was tested by Nanostructural and Molecular Biophysics Laboratory in Technopark Lodz using normal adult human dermal fibroblasts. Survival of cells was tested using spectrophotometry with XTT and was defined as ratio of absorbency of tested probe to absorbency of control probe. Calcein/Ethidium dyeing test was performed according to LIVE/DEAD Viability/Cytotoxicity Kit protocol. Observation was done under Olympus GX71 fluorescence microscope. Results: There was no statistically significant difference for established statistical significance p=0.05 in cuboids dimensions before and after sterilization regardless of sterilization method. In XTT analysis all samples showed higher cytotoxicity against normal, human, adult dermal fibroblast culture when compared to positive control. ANOVA statistical analysis confirmed that 2-octyl cyanoacrylate coating of paper model improved biological behaviour of the material. It decreased cytotoxicity of the model independently of sterilization method. In calcein/ethidium dyeing test due to the high fluorescence of the background caused by cylinders of analysed substance it was impossible to perform the exact analysis of the number of marked cells. Conclusions: Acquired results allow to conclude that Mcor Technology Matrix 300 3D paper-based models can be used in operating room only if covered with cyanoacrylate tissue adhesive. Nemesis relevance: We found no statistically significant difference in cuboids dimensions before and after sterilization regardless of sterilization method. Three-dimensional paper-based models present with high cytotoxicity without coating.

scholarly journals Implementation of a Blind Quality Control Program in Blood Alcohol Analysis

2019 ◽  
Vol 43 (8) ◽  
pp. 630-636 ◽  
Author(s):  
Jackeline Moral ◽  
Callan Hundl ◽  
Dayong Lee ◽  
Maddisen Neuman ◽  
Aimee Grimaldi ◽  
...  
Keyword(s):  
Quality Control ◽  
Linear Regression Analysis ◽  
Control Program ◽  
Multiple Linear Regression Analysis ◽  
Blood Alcohol ◽  
Proficiency Tests ◽  
Science Center ◽  
Quality Control Program ◽  
Significant Difference ◽  
The Difference

Abstract Declared proficiency tests are limited in their use for testing the performance of the entire system, because analysts are aware that they are being tested. A blind quality control (BQC) is intended to appear as a real case to the analyst to remove any intentional or subconscious bias. A BQC program allows a real-time assessment of the laboratory’s policies and procedures and monitors reliability of casework. In September 2015, the Houston Forensic Science Center (HFSC) began a BQC program in blood alcohol analysis. Between September 2015 and July 2018, HFSC submitted 317 blind cases: 89 negative samples and 228 positive samples at five target concentrations (0.08, 0.15, 0.16, 0.20 and 0.25 g/100 mL; theoretical targets). These blood samples were analyzed by a headspace gas chromatograph interfaced with dual-flame ionization detectors (HS-GC-FID). All negative samples produced `no ethanol detected’ results. The mean (range) of reported blood alcohol concentrations (BACs) for the aforementioned target concentrations was 0.075 (0.073–0.078), 0.144 (0.140–0.148), 0.157 (0.155–0.160), 0.195 (0.192–0.200) and 0.249 (0.242–0.258) g/100 mL, respectively. The average BAC percent differences from the target for the positive blind cases ranged from −0.4 to −6.3%, within our uncertainty of measurement (8.95–9.18%). The rate of alcohol evaporation/degradation was determined negligible. A multiple linear regression analysis was performed to compare the % difference in BAC among five target concentrations, eight analysts, three HS-GC-FID instruments and two pipettes. The variables other than target concentrations showed no significant difference (P > 0.2). While the 0.08 g/100 mL target showed a significantly larger % difference than higher target concentrations (0.15–0.25 g/100 mL), the % differences among the higher targets were not concentration-dependent. Despite difficulties like gaining buy-in from stakeholders and mimicking evidence samples, the implementation of a BQC program has improved processes, shown methods are reliable and added confidence to staff’s testimony in court.

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