scholarly journals Gender Difference in Pain Management Among Adult Cancer Patients in Saudi Arabia: A Cross-Sectional Assessment

2021 ◽  
Vol 12 ◽  
Author(s):  
Abdulaziz Alodhayani ◽  
Khalid M. Almutairi ◽  
Jason M. Vinluan ◽  
Norah Alsadhan ◽  
Turky H. Almigbal ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Pain Management ◽  
Cancer Patients ◽  
Cross Sectional Study ◽  
Cancer Type ◽  
Cross Sectional ◽  
Attitudinal Barriers ◽  
Female Cancer Patients ◽  
Tertiary Hospitals ◽  
Harmful Effects

ObjectiveTo compare gender differences in pain management among adult cancer patients in Saudi Arabia and to explore the predictors associated with attitudinal barriers of cancer patients to pain management.MethodsA descriptive cross-sectional study was conducted among 325 cancer patients from tertiary hospitals in Saudi Arabia.ResultOf the total participants, 67.4% were women (N = 219) and 32.6% were men (N = 106). The overall mean scores of the attitudinal barriers questionnaire were 49.51 ± 13.73 in men and 54.80 ± 22.53 in women. The analysis shows significant differences in scores in subscales of tolerance (men = 7.48 ± 2.37), (women = 8.41 ± 3.01) (p = 0.003) and fear of distraction in the course of treatment (men = 6.55 ± 1.34), and (women = 7.15 ± 2.63) (p = 0.008). Female patients reported a more moderate to severe level of pain than men (worst pain in last week of 7.07 ± 1.50, worst pain in last week of 5.84 ± 2.65, respectively). Splitting by gender, the significant predictor for physiology effect domains in male cancer patients includes age, marital status, employment status, monthly income, cancer type, and presence of comorbid disease (p < 0.050). Age was a significant predictor of the domains of fatalism, communication, and harmful effects (p < 0.050) among female cancer patients.ConclusionThe present study revealed significant differences between men and women with attitudinal barriers to cancer pain management. Managing pain requires the involvement of all methods in a comprehensive manner, thus unalleviated pain influences the patient’s psychological or cognitive aspect.

The experience of pain among cancer patients at the University of the Philippines: Philippine General Hospital Cancer Institute—A cross-sectional study.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e24078-e24078
Author(s):  
Harold Nathan C. Tan ◽  
Rogelio Nona Velasco ◽  
Lance Isidore Garcenila Catedral ◽  
Michael Ducusin San Juan ◽  
Corazon Ngelangel ◽  
...  
Keyword(s):  
Pain Management ◽  
Cancer Patients ◽  
Pain Control ◽  
Severe Pain ◽  
Cross Sectional Study ◽  
The Philippines ◽  
Pain Interference ◽  
Cancer Center ◽  
Cross Sectional ◽  
Adequate Pain Management

e24078 Background: Pain is one of the most common and dreaded sequelae of cancer, occurring in approximately 55% of patients. The experience of pain takes a toll on the patients’ quality of life. However, many patients do not receive adequate pain management. This study aimed to determine the prevalence of pain, its severity, and the adequacy of pain management among cancer patients in the Philippines. Methods: A cross-sectional study was conducted at a representative cancer center in the Philippines, enrolling 351 cancer patients. Pain severity was assessed using the Brief Pain Inventory-Short Form (BPI-SF) Filipino. The BPI evaluates pain severity and its impact on daily functioning (pain interference). To ascertain the adequacy of pain control, the pain management index (PMI) was calculated by subtracting the subtracting the severity of pain reported by the patient from the type of analgesic treatment received. Logistic regression analysis was conducted to evaluate the factors associated with worst pain and adequacy of pain management. Data were analyzed using Stata version 16.0, with statistical significance set at p < 0.05. Results: Three hundred three cancer patients (86.3%) experienced pain. Approximately 3 out of 5 patients (n = 208) did not receive adequate pain control, and one-third of patients experienced severe pain (n = 121). Patients who reported severe pain interference (n = 110) had three times greater odds to experience severe pain (OR 3.2, 95% CI 1.82-5.61, p < 0.001). Those patients who had regular follow up were 65% less likely to experience severe pain (OR 0.35, 95% CI 0.16 – 0.78, p = 0.01). Patients who used pain medications (n = 196) were 14 times more likely to experience adequate pain management (OR 14.19, 95% CI 6.53 – 30.83, p < 0.001). Patients who were referred to pain service (n = 25) were seven times more likely to report adequate pain control (OR 6.62, 95% CI 2.50 – 17.56, p < 0.001). Conversely, those patients who reported a severe rating on total pain interference were 75% less likely to experience adequate pain management (OR 0.25, 95% CI 0.17 – 0.35, p < 0.001). Conclusions: Unexpectedly, there was a high prevalence of pain among cancer patients at a representative cancer center in the Philippines. Pain exerts a heavy toll on patients, affecting daily functioning. The undertreatment of pain discovered in this study (59% of cancer patients) is alarming. Timely pain evaluation can help identify the presence of pain and the need for appropriate use of analgesics. The assessment and management of pain is a critical component of cancer care that should not be neglected.

scholarly journals Prevalence and Associated Factors of Depressive Symptoms in Patients with Myasthenia Gravis: A Cross-Sectional Study of Two Tertiary Hospitals in Riyadh, Saudi Arabia

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Mohammed H. Alanazy
Keyword(s):  
Saudi Arabia ◽  
Myasthenia Gravis ◽  
Multiple Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Dose Time ◽  
Prednisolone Dose ◽  
Prevalence Of Depression ◽  
Tertiary Hospitals ◽  
Multiple Regions

Objectives. This study is aimed at elucidating the prevalence of depression in patients with myasthenia gravis (MG) and examining the risk factors associated with depression. Methods. We evaluated adult patients with MG who were recruited from two tertiary hospitals in the central region (Riyadh) of Saudi Arabia. Data were collected with a two-part standardized questionnaire: the first part included data on sociodemographic and clinical features of MG including disease type and duration, therapies, prednisolone dose, time of the last relapse, previous critical care unit admissions, MG status (controlled, partially controlled, or uncontrolled), and comorbid diseases; the second part included items from the previously validated Arabic version of the Patient Health Questionnaire-9 (PHQ-9). Results. In total, 104/150 (69.3%) patients participated (72 females) with a mean age of 38.0±16.0 years. The mean PHQ-9 score was 7.02±6.1. Among all the participants, 27 (26.0%) patients had depression (PHQ‐9≥10). Multiple logistic regression analysis revealed that uncontrolled MG status (OR=12.31, 95%CI=1.13‐133.8, P=0.04) was the only factor independently associated with depression. Collectively, the prevalence of depression among patients of the primary care clinics (PCC) as reported by 5 previous studies across multiple regions of the country was 15.8%. The odds of depression among MG patients were twofold higher than those among PCC patients (OR=2.05, 95%CI=1.30‐3.22, P=0.002). Conclusions. Approximately a quarter of MG patients have depression. Achieving a minimal manifestation or better MG status may decrease the depression rate in these patients.

scholarly journals Anti-Mullerian hormone levels in female cancer patients of reproductive age in Indonesia: A cross-sectional study

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 159
Author(s):  
Achmad Kemal Harzif ◽  
Budi Wiweko ◽  
Putri Addina ◽  
Kartika Iswaranti ◽  
Melisa Silvia ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Cancer Patients ◽  
Reproductive Function ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Cancer Treatments ◽  
Cross Sectional ◽  
Cancer Group ◽  
Anti Cancer ◽  
Female Cancer Patients

Background: Efforts in reproductive preservation for cancer patients have become one of the important aspects of cancer management. In fact, decline in reproductive function is known to occur after exposure to anti-cancer treatments. Measuring anti-Müllerian hormone (AMH) levels is known to be the best parameter in predicting ovarian reserves, which indicates reproductive function. In total, 68% of cancer survivors of reproductive age who underwent anti-cancer treatments suffer from infertility. Meanwhile, ovarian reserves also decrease with increasing age. There is ongoing debate on whether the ovarian reserves of cancer patients could be reduced long before exposure to anti-cancer therapy. Therefore, it is important to know whether ovarian reserves in cancer patients decrease before or after anti-cancer therapy. This can help predict the reproductive function in such cases and the effectiveness of ovarian preservation efforts. Methods: A cross-sectional study was conducted, comparing the AMH levels of 44 female cancer patients of reproductive age before cancer therapy, to 44 non-cancer patients of reproductive age (age matched). The biological ages from both groups were adjusted using the Indonesian Kalkulator of Oocytes. Results: The median age in both groups was 28 years old. The AMH levels in the cancer group were found to be significantly lower in contrast to those in the non-cancer group (1.11 [0.08-4.65] ng/ml vs. 3.99 [1.19- 8.7]; p- value <0.001). Therefore, the biological age in the cancer group was 10 years older than that of the non-cancer group, indicating that ovarian aging occurs earlier in cancer patients. Conclusions: AMH levels of cancer patients of reproductive age were already reduced before cancer therapy, given an older biological age, in contrast to that of the non-cancer patients. Proper counseling and implementation of fertility-preserving methods is highly recommended in this group of patients.

scholarly journals Anti-Mullerian hormone levels in female cancer patients of reproductive age in Indonesia: A cross-sectional study

F1000Research ◽  
2020 ◽  
Vol 8 ◽  
pp. 159
Author(s):  
Achmad Kemal Harzif ◽  
Budi Wiweko ◽  
Putri Addina ◽  
Kartika Iswaranti ◽  
Melisa Silvia ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Cancer Patients ◽  
Reproductive Function ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Cancer Treatments ◽  
Cross Sectional ◽  
Cancer Group ◽  
Anti Cancer ◽  
Female Cancer Patients

Background: Efforts in reproductive preservation for cancer patients have become one of the important aspects of cancer management. In fact, decline in reproductive function is known to occur after exposure to anti-cancer treatments. Measuring anti-Müllerian hormone (AMH) levels is known to be the best parameter in predicting ovarian reserves, which indicates reproductive function. In total, 68% of cancer survivors of reproductive age who underwent anti-cancer treatments suffer from infertility. Meanwhile, ovarian reserves also decrease with increasing age. There is ongoing debate on whether the ovarian reserves of cancer patients could be reduced long before exposure to anti-cancer therapy. Therefore, it is important to know whether ovarian reserves in cancer patients decrease before or after anti-cancer therapy. This can help predict the reproductive function in such cases and the effectiveness of ovarian preservation efforts. Methods: A cross-sectional study was conducted, comparing the AMH levels of 44 female cancer patients of reproductive age before cancer therapy, to 44 non-cancer patients of reproductive age (age matched). The AMH was determined from blood.The biological ages from both groups were adjusted using the Indonesian Kalkulator of Oocytes. Results: The median age in both groups was 28 years old. The AMH levels in the blood of the cancer group were found to be significantly lower in contrast to those in the non-cancer group (1.11 [0.08-4.65] ng/ml vs. 3.99 [1.19- 8.7]; p- value <0.001). Therefore, the biological age in the cancer group was 10 years older than that of the non-cancer group, indicating that ovarian aging occurs earlier in cancer patients. Conclusions: AMH levels of cancer patients of reproductive age were already reduced before cancer therapy, given an older biological age, in contrast to that of the non-cancer patients. Proper counseling and implementation of fertility-preserving methods is highly recommended in this group of patients.

scholarly journals Perception and attitude of healthcare workers in Saudi Arabia with regard to Covid-19 pandemic and potential associated predictors

2020 ◽  
Author(s):  
Mostafa A. Abolfotouh ◽  
Adel F. Almutairi ◽  
Ala'a A. BaniMustafa ◽  
Mohamed A. Hussein
Keyword(s):  
Saudi Arabia ◽  
Perceived Risk ◽  
Healthcare Workers ◽  
Negative Impact ◽  
Cross Sectional Study ◽  
Movement Restriction ◽  
Cross Sectional ◽  
High Concern ◽  
Tertiary Hospitals ◽  
The Government

Abstract Background . Healthcare workers (HCWs) face considerable mental and physical stress caring for patients with Covid-19. They are at higher risk of acquiring and transmitting this virus. Perception and attitude of HCWs in Saudi Arabia regarding Covid-19 were evaluated in comparison with MERS outbreak. Methods. In a cross-sectional study, HCWs at three tertiary hospitals in Saudi Arabia were surveyed via email, by a concern scale about Covid-19 pandemic during 15-30 April, 2020. Concerns of disease severity, governmental efforts to contain it and disease outcomes were assessed using 32 concern-statements in five distinct domains. Multiple regression analyses were used to identify predictors of high concern scores. Results. A total of 844 HCW responded to the survey. Their average age was 40.4±9.5 years, 40.3% were nurses, 58.2% had direct patient contact, and 77.3% were living with family members and/or others. The majority of participants (72.1%) had an overall concern score of 55 or less out of a maximum score of 96 points. Three-fourth of respondents felt at risk of contracting Covid-19 infection at work, 69.1% felt threatened if a colleague contracted Covid-19, 69.9% felt obliged to care for patients infected with Covid-19 while 27.7% did not feel safe at work using the standard precautions. Nearly all HCWs believed that the government should isolate patients with Covid-19 in specialized hospitals (92.9%), agreed with travel restriction to/from areas affected by Covid-19 (94.7%) and felt safe government implemented curfew and movement restriction periods (93.6%). Predictors of high concern scores were; HCWs of Saudi nationality (p<0.001), younger age (p=0.003), undergraduate education (p=0.044), living with others (p=0.003) working in the western region (p=0.003) and direct contact with patients (p=0.018). In comparison with MERS outbreak, HCWs reported significantly higher mean scores about Covid-19 pandemic for overall concern (45.9 versus 40.3, p<0.001). Conclusions. The current study highlights the high concern among HCWs about Covid-19 and identifies the predictors of those with highest concern levels. To minimize the potential negative impact of those concerns on the performance of HCWs during pandemics, measures are necessary to enhance their protection and to minimize the psychological effect of the perceived risk of infection.

Acceptance of coronavirus disease 2019 vaccination by cancer patients in Cyprus: A cross-sectional study

2021 ◽  
pp. 107815522110394
Author(s):  
Zoe Roupa ◽  
Maria Noula ◽  
Monica Nikitara ◽  
Savoula Ghobrial ◽  
Evangelos Latzourakis ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Cancer Patients ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Cancer Type ◽  
Continuous Variables ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Vaccination History ◽  
The Individual

Introduction The acceptance of an individual to be vaccinated following the introduction of a new vaccine is dependent on multiple factors. Governing factors directing one’s decision to be vaccinated against severe acute respiratory syndrome coronavirus 2, however, are currently unknown and the present study aims at researching these factors within the population of cancer patients. Methods A cross-sectional self-administered survey was conducted anonymously between 22 January and 12 February 2021, during the second vaccination phase against severe acute respiratory syndrome coronavirus 2 in Cyprus. The data were collected via an online questionnaire which was formerly used by previously conducted studies. The Mann–Whitney U test was applied for the comparison of means between bivariate variables, while the Kruskal–Wallis test was used for the comparison of means in variables with more than two groups. In addition, Spearman correlation coefficients were applied to explore the correlation of continuous variables. Results The sample size consisted of a total of 211 cancer patients, 64.9% of which were women with a mean age of 52.6 ± 12.4 years. The findings of the current research indicate a moderate vaccination acceptance among cancer patients ( Μ = 3.3 ± 0.7, R = 1–5). Conclusion During the promotion of a vaccine against severe acute respiratory syndrome coronavirus 2 to cancer patients, particular emphasis on specific demographic characteristics, vaccination history and preferred sources of informing the individual are required. In addition, through reviewing the prospective effectiveness and possible outcomes of the specific vaccine according to cancer type and anti-cancer therapy, many of the existing concerns and reservations from cancer patients are expected to be diminished.

scholarly journals Anti-Mullerian hormone levels in female cancer patients of reproductive age in Indonesia: A cross-sectional study

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 159
Author(s):  
Achmad Kemal Harzif ◽  
Budi Wiweko ◽  
Putri Addina ◽  
Kartika Iswaranti ◽  
Melisa Silvia ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Cancer Patients ◽  
Reproductive Function ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Cancer Treatments ◽  
Cross Sectional ◽  
Cancer Group ◽  
Anti Cancer ◽  
Female Cancer Patients

Background: Efforts in reproductive preservation for cancer patients have become one of the important aspects of cancer management. In fact, decline in reproductive function is known to occur after exposure to anti-cancer treatments. Measuring anti-Müllerian hormone (AMH) levels is known to be the best parameter in predicting ovarian reserves, which indicates reproductive function. In total, 68% of cancer survivors of reproductive age who underwent anti-cancer treatments suffer from infertility. Meanwhile, ovarian reserves also decrease with increasing age. There is ongoing debate on whether the ovarian reserves of cancer patients could be reduced long before exposure to anti-cancer therapy. Therefore, it is important to know whether ovarian reserves in cancer patients decrease before or after anti-cancer therapy. This can help predict the reproductive function in such cases and the effectiveness of ovarian preservation efforts. Methods: A cross-sectional study was conducted, comparing the AMH levels of 44 female cancer patients of reproductive age before cancer therapy, to 44 non-cancer patients of reproductive age (age matched). The biological ages from both groups were adjusted using the Indonesian Kalkulator of Oocytes. Results: The median age in both groups was 28 years old. The AMH levels in the cancer group were found to be significantly lower in contrast to those in the non-cancer group (1.11 [0.08-4.65] ng/ml vs. 3.99 [1.19- 8.7]; p- value <0.001). Therefore, the biological age in the cancer group was 10 years older than that of the non-cancer group, indicating that ovarian aging occurs earlier in cancer patients. Conclusions: AMH levels of cancer patients of reproductive age were already reduced before cancer therapy, given an older biological age, in contrast to that of the non-cancer patients. Proper counseling and implementation of fertility-preserving methods is highly recommended in this group of patients.

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