scholarly journals Challenges and Strategies for Pakistan in the Third Wave of COVID-19: A Mini Review

2021 ◽  
Vol 9 ◽  
Author(s):  
Kashif Kamran ◽  
Abid Ali
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Developing Country ◽  
Causative Agent ◽  
Respiratory System ◽  
Virus Disease ◽  
Large Population ◽  
Third Wave ◽  
The Third ◽  
The World ◽  
Novel Coronavirus

The world is currently gripped by the fear of the corona virus disease 2019 (COVID-19) pandemic. The causative agent of COVID-19 is a novel coronavirus known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that attacks humans without prejudice, and primarily targets the respiratory system. Pakistan is a developing country with a large population and a weak economy. Currently, it is facing a major challenge to cope with the outbreak of the COVID-19 pandemic, especially the third wave. This fatal virus has increased its presence many folds in Pakistan. On average, 100 deaths per day were being recorded in the late spring of 2021. Delay in the acquisition of vaccine has slowed down the vaccination program for this disease. This in turn will accelerate the spreading of virus, and thus will lead to a lockdown situation.

scholarly journals Does Concurrent Existence of Asthma or COPD Affect Susceptibility & Outcomes to Novel Coronavirus Infections?

The Physician ◽  
2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Akash Srinivasan ◽  
Indranil Chakravorty ◽  
Koottalai Srinivasan
Keyword(s):  
Respiratory Failure ◽  
Severe Acute Respiratory Syndrome ◽  
Respiratory System ◽  
Chronic Lung Disease ◽  
Lung Diseases ◽  
Healthcare Professionals ◽  
Chronic Lung Diseases ◽  
The World ◽  
Mobile Population ◽  
Novel Coronavirus

The SARS-CoV-2 virus causing COVID-19 pandemic across the world has highlighted the risk of human-to-human transmission, the speed of spread in a globally mobile population and the need for health services to be flexible in their responses to hitherto unknown challenges. One of the hallmarks of COVID-19 is severe acute respiratory syndrome presenting with widespread viral pneumonitis and respiratory failure. It is therefore not unusual for patients with chronic lung diseases such as asthma, COPD, and bronchiectasis to be concerned regarding their particular vulnerability. As healthcare professionals responsible for the care of such patients, it is important to understand how the SARS-CoV-2 virus impacts the respiratory system and the outcomes for patients with chronic lung disease. This review examines the evidence and offers sensible guidance until more is known.

scholarly journals Oral medicine, oral pathology and coronavirus (2019-nCoV)

2020 ◽  
Vol 19 ◽  
pp. e200001
Author(s):  
Hercílio Martelli-Júnior ◽  
Renato Assis Machado ◽  
Daniella R. Barbosa Martelli ◽  
Ricardo Della Coletta
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
World Health Organization ◽  
Causative Agent ◽  
Oral Pathology ◽  
World Health ◽  
Oral Medicine ◽  
The World ◽  
Novel Coronavirus ◽  
Health Organization

In late December 2019, a cluster of unexplained pneumonia cases was diagnosed in Wuhan, China, and few days later, the causative agent of this mysterious pneumonia was identified as a novel coronavirus. This causative virus has been temporarily named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the relevant infected disease has been named as coronavirus disease 2019 (COVID-19) by the World Health Organization respectively. The COVID-19 epidemic is spreading in China and all over the world now...

scholarly journals Exploring Dependence of COVID-19 on Environmental Factors and Spread Prediction in India

2020 ◽  
Author(s):  
Hemant Bherwani ◽  
Ankit Gupta ◽  
Saima Anjum ◽  
Avneesh Anshul ◽  
Rakesh Kumar
Keyword(s):  
Response Surface Methodology ◽  
Relative Humidity ◽  
Environmental Factors ◽  
Severe Acute Respiratory Syndrome ◽  
Virus Disease ◽  
Action Plan ◽  
The Novel ◽  
The World ◽  
Novel Coronavirus ◽  
The Impact

Abstract The pandemic of “Corona Virus Disease 2019” or COVID-19 has taken the world by storm. Majority of nations of the world have been challenged by the novel coronavirus, which is supposedly of zoonotic origin and is known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The present work attempts to evaluate the spread of COVID-19 in India. The methodology of assessment uses SEIR (Susceptible-Exposed-Infectious-Removed) model to establish the impact of socio-behavioural aspect, especially social distancing, affecting the numbers of COVID-19 cases per day. The lockdown initiated by Government of India (GoI) scenario is weighed against a scenario with a possible initiation of community spread due to crowded gatherings in India. The resultant changes, as against the lockdown scenario, has been reported in terms of the increase in the number of cases and stretch of the timeline to mitigate the COVID-19 spread. Impact of environmental factors like temperature and relative humidity have also been analyzed using statistical methods, including Response Surface Methodology (RSM) and Correlation. It has been found that the spread of cases is dependent on environmental conditions, i.e. temperature and relative humidity. This study is expected to help the policymakers and stakeholders to device an improved action plan to alleviate the COVID-19 spread, especially in India.

Recent Patents and Advances on Nanotechnologies against Coronavirus

2020 ◽  
Vol 14 ◽  
Author(s):  
Roozbeh Abedini-Nassab ◽  
Naeemeh Mahdaviyan
Keyword(s):  
Middle East ◽  
Severe Acute Respiratory Syndrome ◽  
Genome Sequencing ◽  
Middle East Respiratory Syndrome ◽  
Detection Methods ◽  
Prevention Strategies ◽  
Infected People ◽  
The Third ◽  
The World ◽  
Novel Coronavirus

: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is one of the seven known coronaviruses infecting humans; HKU1, 229E, NL63, OC43, acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and SARS-CoV-2, the last three of which can cause severe symptoms in patients. COVID-19, previously known as 2019 novel coronavirus, caused by SARS-CoV-2, was first reported in Wuhan, China, in late 2019, and quickly resulted in a major epidemic across the world. Although the origin of SARS-CoV-2 is not clear yet, genome sequencing results suggest that this is the third reported spillover of an animal coronavirus to humans, from 2002. The development of detection, therapeutic, and prevention strategies for COVID-19 is a fundamental task towards curing infected people and competing with the pandemic. Because of their similarities, scientists believe that treatment/detection methods similar to what were used against the illnesses caused by SARS-CoV or MERS-CoV may be effective for curing/detecting COVID-19. Here, we review the recent nanotechnology techniques used for treating and testing SARS-CoV, MERS-CoV, and SARS-CoV-2, and potential therapeutic options for curing COVID-19.

Role of Lachesis and Gripp Heel in the Treatment of COVID-19

2020 ◽  
Vol 33 (03) ◽  
pp. 233-234
Author(s):  
Md Aminul Islam
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Respiratory System ◽  
The World ◽  
Effective Role ◽  
Novel Coronavirus ◽  
Human Death

AbstractFrom December 2019, a new pandemic named Coronavirus Disease 2019 (COVID-2019) has become a key topic of discussion across the world. The reason behind this discussion is the rapid increase in human death due to COVID-19 which has stunned the world. The pathogen of COVID-19 is a novel coronavirus called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which is similar to SARS CoV. SARS-CoV-2 infects mainly the respiratory system which causes the death because there is no effective vaccines or therapeutics against COVID-19. Homoeopathic drugs like Lachesis and Gripp Heel may play an effective role to cure corona patients.

Novel Coronavirus Disease (COVID-19): A Narrative Review Based on Current Status

2020 ◽  
Vol 18 ◽  
Author(s):  
Rina Das ◽  
Dinesh Kumar Mehta ◽  
Meenakshi Dhanawat
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Clinical Symptoms ◽  
Virus Disease ◽  
Relevant Literature ◽  
World Health ◽  
Current Status ◽  
Future Research ◽  
Treatment And Prevention ◽  
First Case ◽  
Novel Coronavirus

Abstract:: A novel virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), appeared and expanded globally by the end of year in 2019 from Wuhan, China, causing severe acute respiratory syndrome. During its initial stage, the disease was called the novel coronavirus (2019-nCoV). It was named COVID-19 by the World Health Organization (WHO) on 11 February 2020. The WHO declared worldwide the SARS-CoV-2 virus a pandemic on March 2020. On 30 January 2020 the first case of Corona Virus Disease 2019 (COVID-19) was reported in India. Now in current situation the virus is floating in almost every part of the province and rest of the globe. -: On the basis of novel published evidences, we efficiently summarized the reported work with reference to COVID-19 epidemiology, pathogen, clinical symptoms, treatment and prevention. Using several worldwide electronic scientific databases such as Pubmed, Medline, Embase, Science direct, Scopus, etc were utilized for extensive investigation of relevant literature. -: This review is written in the hope of encouraging the people successfully with the key learning points from the underway efforts to perceive and manage SARS-CoV-2, suggesting sailent points for expanding future research.

scholarly journals Cutaneous manifestations in children with the new coronavirus infection COVID-19

2021 ◽  
Vol 25 (1) ◽  
pp. 16-24
Author(s):  
O. B. Tamrazova ◽  
A. S. Stadnikova ◽  
E. V. Rudikova
Keyword(s):  
Literature Review ◽  
Viral Infection ◽  
Causative Agent ◽  
The Novel ◽  
Cutaneous Manifestations ◽  
Skin Manifestations ◽  
The World ◽  
Coronavirus Infection ◽  
Novel Coronavirus

In late 2019, a new viral infection appeared in China, which spread around the world, causing a pandemic. The causative agent of the new coronavirus infection COVID-19 is the SARS-CoV-2 coronavirus. The review presents modern data on the epidemiology, pathogenesis and course of the novel coronavirus infection COVID-19 in children. Chinese, American and European scientists have described a variety of cutaneous manifestations in children with COVID-19. The article provides a literature review of the cutaneous manifestations of COVID-19 coronavirus infection in children. During our own observation of 301 patients with coronavirus infection COVID-19 caused by SARS-CoV-2 at the Bashlyaevs Children Hospital in Moscow from May 17 to November 16, 2020, it was revealed that 39 (13 %) patients had skin manifestations. The article presents a classification of skin manifestations characteristic of COVID-19. A brief description of each group is given.

scholarly journals Does the novel coronavirus 2019 like heart more than the other family members of coronaviruses?

2020 ◽  
Vol 12 (2) ◽  
pp. 156-157
Author(s):  
Mohammad Mostafa Ansari Ramandi ◽  
Mohammadreza Baay ◽  
Nasim Naderi
Keyword(s):  
Middle East ◽  
Severe Acute Respiratory Syndrome ◽  
Family Members ◽  
Middle East Respiratory Syndrome ◽  
The Other ◽  
The Novel ◽  
The World ◽  
Future Challenges ◽  
Novel Coronavirus ◽  
Coronavirus Infections

The disaster due to the novel coronavirus disease 2019 (COVID-19) around the world has made investigators enthusiastic about working on different aspects of COVID-19. However, although the pandemic of COVID-19 has not yet ended, it seems that COVID-19 compared to the other coronavirus infections (the Middle East Respiratory Syndrome [MERS] and Severe Acute Respiratory Syndrome [SARS]) is more likely to target the heart. Comparing the previous presentations of the coronavirus family and the recent cardiovascular manifestations of COVID-19 can also help in predicting possible future challenges and taking measures to tackle these issues.

scholarly journals Pandemic Fatigue: A Challenge in Combatting against COVID-19

2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Mohd Rohaizat Hassan ◽  
Syed Sharizman Syed Abdul Rahim ◽  
Mohammad Saffree Jeffree
Keyword(s):  
Third Wave ◽  
Psychological Consequences ◽  
The Third ◽  
Social Structural ◽  
The World ◽  
Protective Behaviours ◽  
Over Time ◽  
Simple Definition

  The COVID -19 pandemic has hit the world for a period of a year and a half; it has been a triple crisis, with medical, economic, and psychological consequences. After 18 months of going through a pandemic, this includes not only facing the transmission of SARS CoV-2 virus but also restricted movements. Communities are now facing pandemic fatigue starting as early as the third wave of increased cases in September 2020. Pandemic fatigue is the stage when the initial enthusiasm and eagerness to tackle the crisis is replaced by feelings of exhaustion. In a simple definition, pandemic fatigue is understood as demotivation to follow recommended protective behaviours. It is a natural and expected reaction to sustained and unresolved adversity in people’s lives, evolving gradually over time and affected by several emotions, experiences, and perceptions as well as the cultural, social, structural, and legislative environment.

scholarly journals Molecular Docking Study of the Potential Relevance of the Natural Compounds Isoflavone and Myricetin to COVID-19

2021 ◽  
Vol 25 (3) ◽  
pp. 271-282
Author(s):  
Didik Priyandoko ◽  
◽  
Wahyu Widowati ◽  
Mawar Subangkit ◽  
Diana Jasaputra ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Severe Acute Respiratory Syndrome ◽  
Active Sites ◽  
Docking Study ◽  
Binding Mode ◽  
Molecular Docking Study ◽  
Wuhan City ◽  
The World ◽  
Novel Coronavirus ◽  
Proteins Interactions

The 2019 novel coronavirus (2019-nCoV) or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly from its origin in Wuhan City, Hubei Province, China, to the rest of the world. The efficacy of herbal treatment in the control of contagious disease was demonstrated during the 2003 outbreak of severe acute respiratory syndrome (SARS). Natural compound used for this study were isoflavone and myricetin. Molecular docking was performed to analyze binding mode of the compounds towards 12 proteins related to COVID-19. The prediction shows that isoflavone and myricetin have moderate probability of antiviral activity. All of the docked compounds occupied the active sites of the proteins related to COVID-19. Based on QSAR and molecular docking, interactions were predicted with 10 out of 12 potential COVID-19 proteins for myricetin and with 9 out of 12 proteins interactions for isoflavone. A potential disease alleviating action is suggested for isoflavone and myricetin in the context of COVID-19 infection.

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