scholarly journals Risk Factors for Failure of Hard Palate Mucoperiosteal Flap Repair of Acquired Oronasal Communication in Dogs: A Pilot Study

2021 ◽  
Vol 8 ◽  
Author(s):  
Kendall Taney ◽  
Mark M. Smith ◽  
Nathan P. Cummings ◽  
Alicia J. Lozano
Keyword(s):  
Risk Factors ◽  
Body Weight ◽  
Pilot Study ◽  
Hard Palate ◽  
Clinical Signs ◽  
Strict Adherence ◽  
Time Of Surgery ◽  
Initial Surgery ◽  
Potential Risk Factors ◽  
Mucoperiosteal Flap

The objective of this retrospective pilot study was to describe potential risk factors for failure of hard palate mucoperiosteal flaps (HPF) transposed for closure of oronasal communication. Dogs (n = 28) with acquired oronasal communication defects were included in the study population. Functional success of an HPF was determined by visual inspection at the last examination and lack of clinical signs. Risk factors for HPF failure including age, sex, body weight, presence of neoplasia at the time of surgery, presence of neoplasia after surgery due to incomplete or narrow margins, use of CO2 laser, previous surgeries in the same location, HPF blood supply, size of the HPF as a percentage of the total area of the hard palate mucoperiosteum, and distance traveled by the apex of the HPF were evaluated using descriptive statistics and unadjusted logistic regression modeling. Seven out of 28 (25%) hard palate flap procedures resulted in persistent oronasal communication and were considered failures. Body weight (Median: 17 vs. 25 kg, OR = 0.94, 80% CI = 0.90, 0.99), presence of neoplasia at the time of surgery (86 vs. 57%, OR = 4.50, 80% CI = 1.01, 20.06), HPF area (Median: 0.49 vs. 0.41, OR = 84.40, 80% CI = 1.66, 4,298) and apex travel distance (Median: 2.06 vs. 0.67, OR = 5.15, 80% CI = 2.14, 12.38) were associated with flap failure. Within this sample, the presence of neoplasia at the time of initial surgery, increasing the area of the HPF, and distance traveled by the HPF apex were associated with a greater odds of HPF failure. Further studies with larger sample sizes are needed to confirm repeatability of these results. HPFs remain a viable surgical option for closure of oronasal communication. Careful surgical planning, strict adherence to surgical principles, and awareness of anatomical limitations can increase the likelihood of success.

scholarly journals Epidemiological and Molecular Investigation of Ocular Fungal Infection in Equine from Egypt

2020 ◽  
Vol 7 (3) ◽  
pp. 130
Author(s):  
Amin Tahoun ◽  
Helmy K. Elnafarawy ◽  
Ehab Kotb Elmahallawy ◽  
Abdelhamed Abdelhady ◽  
Amira M. Rizk ◽  
...  
Keyword(s):  
Risk Factors ◽  
Fungal Infection ◽  
Prevalence Rate ◽  
Clinical Signs ◽  
Fungal Species ◽  
Potential Risk Factors ◽  
Polymerase Chain ◽  
Penicillium Spp ◽  
Morphological And Molecular Characterization

Diagnosis and treatment of ocular fungal infection in equine seems very challenging for owners and clinicians. The present study aimed to identify and characterize fungal species isolated from the eyes of clinically healthy and diseased equines (N = 100) from Dakahlia Governorate, Egypt. The work also involved morphological and molecular characterization of the major fungal species. In addition, correlations between the occurrence of isolated fungi and some of the potential risk factors were also investigated. Interestingly, the prevalence rate of ocular mycosis in all examined equines in the study was 28% and there were major clinical signs associated with ocular fungal infection. Moreover, the identified fungal species included Aspergillus flavus, A. fumigatus, A. niger, Penicillium spp., Mucor spp., and Alternari spp. with a corresponding prevalence rate of 63.9%, 27.8%, 15.3%, 18.1%, 13.9%, and 4.2%, respectively, in healthy equine eyes, while their prevalence in diseased equine eyes was 57.1%, 32.1%, 21.4%, 7.1%, 3.6%, and 0%. Furthermore, a statistical significant association (p < 0.05) was found between the frequency of isolation of A. fumigatus and Penicillium and several risk factors (breed, sex, and ground type), while the remaining risk factors and occurrence of fungi were not statistically correlated. A subset of the Aspergillus species samples positive by polymerase chain reaction (PCR) were sequenced and their phylogenetic analysis identified three species of Aspergillus. Taken together, our study provides novel data related to the occurrence of ocular mycosis in equine in Egypt. Given the zoonotic potential of some identified fungi, our data may be helpful for implementation of novel diagnostic and therapeutic strategies for combating this sight-threatening infection in equine.

Potential risk factors of persistent postural-perceptual dizziness: a pilot study

2021 ◽  
Author(s):  
Ling Li ◽  
Songbin He ◽  
Haipeng Liu ◽  
Meilun Pan ◽  
Fangyu Dai
Keyword(s):  
Risk Factors ◽  
Pilot Study ◽  
Potential Risk ◽  
Potential Risk Factors

scholarly journals Retrospective Analyses of Potential Risk Factors for Posterior Capsule Opacification after Cataract Surgery

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Shuang Wu ◽  
Nianting Tong ◽  
Lin Pan ◽  
Xiaohui Jiang ◽  
Yanan Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Cataract Surgery ◽  
Potential Risk ◽  
Posterior Capsule Opacification ◽  
Posterior Capsule ◽  
Factors Associated ◽  
Time Of Surgery ◽  
Department Of Ophthalmology ◽  
Potential Risk Factors

Purpose. To evaluate the potential risk factors of posterior capsule opacification (PCO) after cataract surgery. Methods. Data on PCO patients diagnosed from September 2015 to May 2017 were obtained from the Department of Ophthalmology at Qingdao Municipal Hospital, Qingdao, China. The factors associated with PCO were assessed using Pearson's χ2 test for univariate analyses and logistic regression for multivariate analyses. Results. Eyes (652) from 550 patients were enrolled in this study. All patients were diagnosed with PCO/non-PCO and had <3 years of follow-up after surgery. The numbers of PCO and non-PCO were 108 eyes and 544 eyes, respectively. Statistically significant associations with PCO were found for age at the time of surgery (χ2 = 78.504; p<0.001), diabetes (χ2 = 4.829; p=0.028), immune diseases (χ2 = 4.234; p=0.004), high myopia (χ2 = 5.753; p=0.016), lens nucleus hardness (χ2 = 11.046; p=0.026), surgery type (χ2 = 11.354; p=0.001), a history of vitrectomy (χ2 = 4.212; p=0.004), ocular inflammation (χ2 = 6.01; p=0.009), and the intraocular lens (IOL) type (χ2 = 8.696; p=0.003). Multivariable data analyses using logistic regression analyses of the variables showed that age at the time of surgery <60 years, diabetes, lens nucleus hardness of III–V, extracapsular cataract extraction (ECCE), postvitrectomy, and hydrophilic IOLs were significant independent risk factors associated with PCO. Conclusions. Age <60 years, diabetes, lens nucleus hardness of III–V, ECCE, postvitrectomy, and a hydrophilic IOL were significantly associated with the formation of PCO. Estimation of the incidence of and risk factors for PCO should help in patients counseling and in the design of treatment protocols to reduce or prevent its development.

scholarly journals P.096 Optimizing the Use of Continuous EEG Monitoring in Neonatal Encephalopathy

2021 ◽  
Vol 48 (s3) ◽  
pp. S46-S47
Author(s):  
F Din ◽  
S MacFarland ◽  
D Wilson ◽  
CD Hahn
Keyword(s):  
Risk Factors ◽  
Therapeutic Hypothermia ◽  
Potential Risk ◽  
Clinical Signs ◽  
Term Neonates ◽  
Continuous Eeg ◽  
Continuous Eeg Monitoring ◽  
Potential Risk Factors ◽  
Ischemic Encephalopathy

Background: Newborns with hypoxic-ischemic encephalopathy (HIE) are at high risk for seizures, the majority of which have no clinical signs and therefore require continuous electroencephalographic (cEEG) monitoring for their detection. We sought to determine which neonates are at highest risk for seizures in order to optimize allocation of scarce cEEG resources. Methods: We identified term neonates diagnosed with HIE who underwent at least 24 hours of protocol-based cEEG monitoring between 2016 and 2019. We quantified seizure incidence, timing and burden, and correlated these with potential risk factors such as HIE severity, use of therapeutic hypothermia, preceding suspected clinical seizures, amplitude-integrated EEG (aEEG) background and patterns suspicious for seizures, and use of anti-seizure drugs. Results: cEEG monitoring was completed in 218 neonates with HIE, of whom 164 (75%) underwent therapeutic hypothermia. Preceding clinical/aEEG seizures occurred in 147 (67%), 99 (67%) of whom had been cooled but only 22 (10%) had cEEG-confirmed seizures. Characterization of seizure burden and correlation with potential risk factors is ongoing. Conclusions: Although seizures are commonly suspected in neonates with HIE, they are infrequently confirmed during cEEG monitoring, creating opportunities for more efficient risk-based allocation of cEEG resources.

scholarly journals Management of severe tracheal stenosis caused by repeated endotracheal intubation in a patient of myasthenia gravis

Pulse ◽  
1970 ◽  
Vol 3 (1) ◽  
pp. 25-26
Author(s):  
MI Hussain ◽  
L Aziz
Keyword(s):  
Risk Factors ◽  
Body Weight ◽  
Myasthenia Gravis ◽  
Tracheal Stenosis ◽  
Potential Risk ◽  
Autoimmune Disorder ◽  
Underlying Disease ◽  
Myasthenic Crisis ◽  
Potential Risk Factors ◽  
Post Intubation

Myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular junction. The disease is characterized by exacerbation and remission of the symptoms from time to time. Myasthenic crisis is a serious complication of MG and is defined as weakness from acquired MG that is severe enough to require intubations [1]. Myasthenic crisis may complicate in 15-20% of patient with MG [2], [3]. Most patients require ventilation for a brief period, usually less than two weeks [4]. Repeated intubations may cause tracheal stenosis. The potential risk factors for post-intubation subglottic stenosis include, the underlying disease requiring endotracheal intubations(EI), the age and body weight, the duration and number of EIs, absence of sedation and the occurance of infections, hypotensive or hypoxic events during the period of EI and traumatic EI [5], [6].Key words: Tracheal stenosis, Repeated intubations, Myasthenia gravis.DOI: 10.3329/pulse.v3i1.6550Pulse Vol.3(1) July 2009 p25-26

Why do we suffer more ACL injuries in the cold? A pilot study into potential risk factors

2017 ◽  
Vol 23 ◽  
pp. 14-21 ◽  
Author(s):  
Robert Csapo ◽  
Ramona Folie ◽  
Simona Hosp ◽  
Michael Hasler ◽  
Werner Nachbauer
Keyword(s):  
Risk Factors ◽  
Pilot Study ◽  
Potential Risk ◽  
Acl Injuries ◽  
Potential Risk Factors

scholarly journals Clinical and laboratory investigation on the recurrence of the umbilical hernia after herniorrhaphy in bovine calves

2018 ◽  
Vol 16 (3) ◽  
pp. 464-470 ◽  
Author(s):  
Md. Mehedi Jaman ◽  
Pravin Mishra ◽  
Marzia Rahman ◽  
Md. Mahmudul Alam
Keyword(s):  
Risk Factors ◽  
Body Weight ◽  
Laboratory Investigation ◽  
Umbilical Hernia ◽  
Clinical Signs ◽  
Postoperative Management ◽  
Absorbable Suture ◽  
Suture Materials ◽  
Or Management ◽  
Suture Patterns

This study was performed to investigate the recurrence of the umbilical hernia in bovine calves at Veterinary Teaching Hospital (VTH), Bangladesh Agricultural University, Mymensingh. A total of 34 animals were admitted to VTH diagnosed to have the umbilical hernia, among them 13 were recurrent cases. The diagnosis of umbilical hernia was based on the disease history, clinical signs, palpation, needle exploration, and auscultation. The risk factors like age, sex, breed, body weight, the season of affection, size of the hernial ring, suture materials, error in suture patterns and involvement of infections in the recurrence were considered.  Infected samples were collected from recurrent patients with infected umbilicus region, and subjected to bacteriological analysis. We found the recurrence percentage was higher in the crossbred (44%) than that in the indigenous (22.22%) calves. It was also observed that recurrence percentage was higher in male (42.11%) than those in female (33.33%) patients. The recurrence percentage was also higher in calves aged below three months (40.74%) than the calves of above three months (28.57%). It was found that recurrence percentage was most frequent in summer (46.15%) and the least in the winter (30%). Among 13 recurrent bovine calves after herniorrhaphy, three calves returned to VTH with umbilical abscess, six calves recurred due to non-infectious causes like failure of suture materials, errors in suture pattern or management fault and 4 calves recurred with both umbilical abscess and non-infectious causes. From this study, it may be concluded that synthetic absorbable suture materials with secured suture pattern and good postoperative management may help in reducing the recurrence of an umbilical hernia. J. Bangladesh Agril. Univ. 16(3): 464–470, December 2018

A serosurvey of Mycobacterium avium subsp. paratuberculosis infection of goats in the North of Portugal

2021 ◽  
Keyword(s):  
Risk Factors ◽  
Mycobacterium Avium ◽  
Clinical Signs ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Logistic Regression Models ◽  
The North ◽  
Potential Risk Factors ◽  
Study Support ◽  
Mycobacterium Avium Subsp Paratuberculosis

Abstract To better understand the epizootiology of caprine paratuberculosis in the North of Portugal, a cross-sectional study was conducted from 2014 to 2015. The seroprevalence and risk factors for Mycobacterium avium subsp. paratuberculosis (Map) seropositivity were evaluated. Antibodies against Map were determined by a commercial ELISA. In 936 sera tested from 56 goat herds, 120 (12.8%, 95% CI: 10.8–15.1%) goats and 34 (60.7%, 95% CI: 47.6–72.4%) herds were positive. Risk factors for seropositivity were investigated by logistic regression models. The odds of Map seropositivity were found to be higher for animals with clinical signs, OR = 5.1 (95% CI: 2.7–9.6%), animals belonging to herds with previous wasting disease, OR = 2.3 (95% CI: 1.1–4.8%), and accumulation of manure in the herd, OR = 3.1 (95% CI: 1.7–5.7%). The potential risk factors identified in this study support the current recommendations for the control of paratuberculosis in these and other animals.

Fatigue fracture of an uncemented Zweymüller femoral stem at the neck–shoulder junction

2020 ◽  
Vol 13 (11) ◽  
pp. e236328
Author(s):  
Thijs Andreas Nijenhuis ◽  
Stijn Albertus Andreas Nicolaas Bolink ◽  
Roy Bernardus Gerardus Brokelman
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Body Weight ◽  
Femoral Stem ◽  
Case Description ◽  
Related Factors ◽  
Implant Positioning ◽  
Neck Fracture ◽  
Potential Risk Factors ◽  
Stem Fracture

A fracture through the neck of the femoral stem in total hip arthroplasty is extremely rare. We report a neck fracture of a cementless Zweymüller stem, one of the most implanted stems worldwide. According to our knowledge, this is the first thorough case description of a neck fracture of a cementless Zweymüller stem. The case concerns a 53-year-old man, with a body weight of 103 kg and a body mass index of 31. We consider potential risk factors for a femoral stem fracture, such as patient-related factors, suboptimal implant positioning, surgical technique and implant characteristics.

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