scholarly journals The Site of Origin of Canine Abdominal Masses Correlates with the Risk of Malignancy: Retrospective Study of 123 Cases

Animals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 962
Author(s):  
Paola Valenti ◽  
Valeria Pellegrino ◽  
Luisa Vera Muscatello ◽  
Barbara Brunetti ◽  
Elisa Zambon ◽  
...  
Keyword(s):  
Abdominal Mass ◽  
Case Series ◽  
Malignant Neoplasm ◽  
Common Finding ◽  
Surgical Removal ◽  
Anatomical Location ◽  
Histopathological Diagnosis ◽  
Minimum Diameter ◽  
Abdominal Masses ◽  
The Masses

The detection of an abdominal mass represents a common finding in clinical practice. The aim of this study was to retrospectively describe the tissue distribution and diagnosis of abdominal masses amenable to surgical removal in a canine population. Dogs with abdominal masses with a minimum diameter of 3 cm were selected. Cases were classified, based on the anatomical location, as splenic, gastrointestinal, hepatobiliary, genital, and masses not associated with any organ. Masses were surgically removed and formalin-fixed for the histological examination. Collected data were statistically analyzed. A total of 123 masses were collected from 122 dogs. Sixty-nine masses were classified as malignant neoplasia, 15 as benign, and 39 as non-neoplastic. The abdominal masses were 5.8-fold more likely to be malignant if located in the gastrointestinal tract (p = 0.01). A significant association between the size and the site of the masses was identified, the masses not associated with any organ being larger than the genital and splenic lesions (p = 0.008). This case series describes the most frequent location in association with the histopathological diagnosis of canine abdominal masses and suggests that the gastrointestinal location was related to a higher risk of representing a malignant neoplasm.

scholarly journals L’Ambulatorio protetto: visitare ai tempi del Covid-19

QUADERNI ACP ◽  
2021 ◽  
Vol 28 (4) ◽  
pp. 173
Author(s):  
Davide Ursi ◽  
Cristina Scozzafava ◽  
Sara Immacolata Orsini ◽  
Andrea Apicella
Keyword(s):  
Emergency Department ◽  
Differential Diagnosis ◽  
Histological Analysis ◽  
Abdominal Mass ◽  
Sudden Onset ◽  
Lymphatic Malformation ◽  
Surgical Removal ◽  
Lymphatic Malformations ◽  
Cystic Structure ◽  
Abdominal Masses

A 3-months baby comes to our emergency department for an abdominal mass of elastic consistency that suddenly appeared for a week and grown exponentially in the last few days. Blood examinations identify a septic state of the child, and the emergency CT recognizes the abdominal mass’s cystic structure. The surgical removal and the histological analysis will confirm the diagnosis of Infected Common Macrocystic Lymphatic Malformation. This case allows us to remember to pediatricians the main features of Cystic Lymphatic Malformations that should always be considered during the differential diagnosis of abdominal masses of sudden onset in an infant.

scholarly journals Intraoperative Ultrasound Applications in Intracranial Surgery

2021 ◽  
Vol 8 ◽  
Author(s):  
Andy Shores ◽  
Alison M. Lee ◽  
S. T. Kornberg ◽  
Chris Tollefson ◽  
Marc A. Seitz ◽  
...  
Keyword(s):  
Skull Fracture ◽  
Intraoperative Ultrasound ◽  
Case Series ◽  
Surgical Removal ◽  
Advanced Imaging ◽  
Surgical Biopsy ◽  
Intracranial Surgery ◽  
Canine Tumors ◽  
Intracranial Lesions ◽  
The Masses

The methods and use of intraoperative ultrasound in 33 canine and five feline patients and its ability to localize and identify anatomical structures and pathological lesions in canines and felines undergoing intracranial surgery are described from a case series. All were client-owned referral patients admitted for neurologic evaluation, with an advanced imaging diagnosis of an intracranial lesion, and underwent surgical biopsy or surgical removal of the lesion. Medical records, retrieval and review of imaging reports, and characterization of findings for all canine and feline patients show that intraoperative ultrasound guidance was used in intracranial procedures during the period of 2012 and 2019. Twenty-nine of the canine patients had intracranial tumors. The remainder had various other conditions requiring intracranial intervention. Three of the feline patients had meningiomas, one had a depressed skull fracture, and one had an epidural hematoma. The tumors appeared hyperechoic on intraoperative ultrasound with the exception of cystic portions of the masses and correlated with the size and location seen on advanced imaging. Statistical comparison of the size of images seen on ultrasound and on MRI for 20 of the canine tumors revealed no statistical differences. Neuroanatomical structures, including vascular components, were easily identified, and tumor images correlated well with preoperative advanced imaging. The authors conclude that intraoperative ultrasound is a valuable asset in intracranial mass removals and can augment surgical guidance in a variety of intracranial disorders that require surgery. This is the first known publication in veterinary surgery of using intraoperative ultrasound as a tool in the operating theater to identify, localize, and monitor the removal/biopsy of intracranial lesions in small animals undergoing craniotomy/craniectomy.

scholarly journals A Case Report of an Abdominal Wall Endometrioma

2021 ◽  
Vol 11 (11) ◽  
pp. 261-264
Author(s):  
Saima Najam ◽  
Messaoud Bounnah
Keyword(s):  
Abdominal Pain ◽  
Abdominal Wall ◽  
Abdominal Mass ◽  
Young Patients ◽  
Surgical Removal ◽  
Histopathological Diagnosis ◽  
Normal Delivery ◽  
Uterine Surgery ◽  
History Of ◽  
The Right

Abdominal wall endometrioma (AWE) is one of the rarest forms of the endometriosis, and usually found in the young patients, average age is 35years. The most common triad of the symptoms is, abdominal mass at or near the scar, cyclical pain and history of previous caesarean or any other gynecological surgery. Exact pathogenesis is unknown as average time of its presentation in the patients is highly variable from 3 months till 2 decades. It can be suspected on ultrasonography and CT scan and MRI are the modalities used to assess and stage the lesion prior to the surgery. Histopathological diagnosis is confirmatory. We are reporting 30 years old, Para 2, with history of first caesarean section 6 years ago followed by the normal delivery. She presented with the history of cyclical abdominal pain with the feeling of abdominal lump from last 3 months. On examination a slightly tender 5*4 cm extra abdominal mass was palpable above the right half of the previous transverse scar of the caesarean. After evaluation endometriosis was suspected and the patient opted for the surgical resection of the mass. The mass was removed in collaboration with the surgeons and the histopathology confirmed the diagnosis of the AWE. Conclusion: AWE is a dynamic yet incompletely known entity as a result of increasing number of the caesarean and gynecological procedures. It should be kept in the differential diagnosis of the patients coming with the cyclical abdominal pain and abdominal lump with the history of previous uterine surgery. Ultrasound and MRI are the main aiding modalities but the confirmation of the diagnosis is made only after histopathology. The surgical removal of the mass with negative margins represents the current best treatment. Key words: Abdominal wall, endometriosis, magnetic resonance imaging, ultrasonography.

scholarly journals Study on clinical profile and management of abdominal tumours in children

2019 ◽  
Vol 6 (2) ◽  
pp. 447
Author(s):  
Varsha S. Kane ◽  
Babu P. Ubale
Keyword(s):  
Abdominal Mass ◽  
The Other ◽  
Clinical Profile ◽  
Urinary System ◽  
Challenging Problem ◽  
Intravenous Pyelography ◽  
Abdominal Masses ◽  
The Masses ◽  
Abdominal Tumours ◽  
Routine Investigations

Background: The discovery of an abdominal mass in a child usually presents a challenging problem in the diagnosis and treatment to the paediatrician, surgeon and urologist. Because of the heterogenicity of the lesion knowledge of differential of a mass in abdomen is essential for the logical evaluation of a child.Methods: The present study comprises of 25 children who presented with an intra-abdominal mass were included. The medical causes of the abdominal masses i.e. hepatosplenomegaly and leukemias were excluded. All patients admitted were routine investigated and whichever necessary. After the diagnosis, surgery was done wherever indicated and post-operatively the diagnosis was confirmed after the histopathological report.Results: All the cases presented with mass in abdomen while the other presentations were pain in abdomen (36%), fever (20%) and haematuria and vomiting (16% each). It was found that 64% of the masses were urological in origin while 36% of the masses were non-urological in origin. 21 (84%) patients underwent surgery, 10 (40%) patients took chemotherapy, 9 (36%) patients took radiotherapy.Conclusions: Routine investigations were only helpful in diagnosing the infection in infecting cases. Most reliable specific investigation was intravenous pyelography. It was found that majority of the abdominal masses in children were arising from urinary system. Correlation between pre-operative and post-operative diagnosis was found almost consistent.

scholarly journals Fifteen-minute consultation: A general paediatrician’s guide to oncological abdominal masses

2019 ◽  
Vol 104 (3) ◽  
pp. 129-134
Author(s):  
Lena Uzunova ◽  
Helen Bailie ◽  
Matthew J Murray
Keyword(s):  
Abdominal Mass ◽  
Anatomical Location ◽  
Initial Management ◽  
Abdominal Masses ◽  
The Family ◽  
Associated Symptoms ◽  
General Paediatrician ◽  
Life Threatening ◽  
Oncology Centre ◽  
Structured Approach

The identification of an abdominal mass in a child, either coincidental or symptomatic, may be due to a tumour. An abdominal tumour may present with life-threatening symptoms, requiring prompt assessment and management. Although the discovery of such a finding usually warrants inpatient transfer or outpatient referral to the tertiary oncology centre, the initial evaluation, management and communication with the family by the general paediatrician is crucial. A thorough history and examination, which includes an organised, structured approach to abdominal masses, is paramount. The anatomical location of the mass, age of the patient and the presence of any associated symptoms or signs must be considered together in order to formulate a list of potential differential diagnoses and guide the next appropriate investigations. This article aims to guide general paediatricians through the assessment and initial management of a child presenting with an abdominal mass suspected to be a tumour.

On the necessity for postchemotherapy surgery for residual abdominal masses in metastatic nonseminomatous germ cell tumors (NSGCT) of testis

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. 5088-5088
Author(s):  
S. J. Harland ◽  
R. Welch ◽  
R. Huddart ◽  
S. Stenning ◽  
P. Pollock ◽  
...  
Keyword(s):  
Abdominal Mass ◽  
Germ Cell Tumors ◽  
Good Prognosis ◽  
Retroperitoneal Lymph Node Dissection ◽  
Chemotherapy Response ◽  
Abdominal Masses ◽  
Residual Masses ◽  
One Year ◽  
The Uk ◽  
The Masses

5088 Background: Residual abdominal masses after chemotherapy for metastatic NSGCT of testis may contain viable tumor-derived tissue which can be a nidus for relapse of disease, particularly when the tissue is frankly malignant. This justifies routine retroperitoneal lymph node dissection (RPLND) for large masses where malignant tissue is found at an appreciable rate. Yet RPLND is often carried out for smaller, or even absent, residual masses and differentiated teratoma (TD) is commonly found. There is little data on the consequence of leaving these smaller masses in situ, which is the practice in some units in the UK. Methods: 51 patients were identified from the MRC patients entered into the TE20 trial of 3 vs 4 cycles of BEP for good prognosis metastatic NSGCT who fell into the following category: metastatic NSGCT, residual abdominal mass only, unresected post-chemotherapy, response evaluation: CR or PR marker -ve. Collaborators were asked to report on mass size, relapse status, whether an operation was ever performed and the latest CT appearance. Results: 51/51 responses were received. Follow-up from the end of chemotherapy was >3years in all but two cases and the median was 5 years. When later surgery was carried out, for persistence or enlargement of the masses, the specimens contained TD with or without necrosis. One patient suffered a relapse one year after the surgery which took place 4.5 years after chemotherapy. Of the 41 patients who did not undergo surgery, 37 were considered on subsequent CTs to have normal appearances without further treatment. Conclusions: For patients with small residual masses in good prognosis metastatic disease no short or medium term benefit from routine surgery would have been seen. Its role in this situation is therefore questionable. For larger (>14mm) masses the need for routine surgery merits further study. [Table: see text] No significant financial relationships to disclose.

Imaging Features of Primary Tumors of the Hand

2020 ◽  
Vol 16 ◽  
Author(s):  
Filippo Boriani ◽  
Edoardo Raposio ◽  
Costantino Errani
Keyword(s):  
Soft Tissue ◽  
Soft Tissues ◽  
Epithelioid Sarcoma ◽  
Case Series ◽  
Malignant Neoplasm ◽  
Benign Tumors ◽  
Imaging Features ◽  
Primary Tumors ◽  
Therapeutic Decisions ◽  
Tumors Of The Hand

: Musculoskeletal tumors of the hand are a rare entity and are divided into skeletal and soft tissue tumors. Either category comprises benign and malignant or even intermediate tumors. Basic radiology allows an optimal resolution of bone and related soft tissue areas, ultrasound and more sophisticated radiologic tools such as scintigraphy, CT and MRI allow a more accurate evaluation of tumor extent. Enchondroma is the most common benign tumor affecting bone, whereas chondrosarcoma is the most commonly represented malignant neoplasm localized to hand bones. In the soft tissues ganglions are the most common benign tumors and epithelioid sarcoma is the most frequently represented malignant tumor targeting hand soft tissues. The knowledge regarding diagnostic and therapeutic management of these tumors is often deriving from small case series, retrospective studies or even case reports. Evidences from prospective studies or controlled trials are limited and for this lack of clear and supported evidences data from the medical literature on the topic are controversial, in terms of demographics, clinical presentation, diagnosis prognosis and therapy.The correct recognition of the specific subtype and extension of the tumor through first line and second line radiology is essential for the surgeon, in order to effectively direct the therapeutic decisions.

scholarly journals Local Chemotherapy as an Adjuvant Treatment in Unresectable Squamous Cell Carcinoma: What Do We Know So Far?

2021 ◽  
Vol 28 (4) ◽  
pp. 2317-2325
Author(s):  
Luigi Bennardo ◽  
Francesco Bennardo ◽  
Amerigo Giudice ◽  
Maria Passante ◽  
Stefano Dastoli ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Gold Standard ◽  
Systemic Chemotherapy ◽  
Standard Treatment ◽  
Case Reports ◽  
Case Series ◽  
Surgical Removal ◽  
Local Chemotherapy

Background: Squamous cell carcinoma (SCC) is one of the most common cancers involving skin and oral mucosa. Although this condition’s gold-standard treatment is the surgical removal of the lesions, the physician must propose alternative treatments in some cases due to the patient’s ineligibility for surgery. Among the available alternative therapies, local chemotherapy may represent an initial treatment in combination with radiotherapy or systemic chemotherapy due to the low frequency of side-effects and the lack of necessity for expensive devices. Methods: In this paper, we review all available literature in various databases (PubMed, Scopus-Embase, Web of Science), proposing local chemotherapy as a treatment for cutaneous and oral SCC. Exclusion criteria included ocular lesions (where topical treatments are common), non-English language, and non-human studies. Results: We included 14 studies in this review. The majority were case reports and case series describing the treatment of non-resectable localized SCC with either imiquimod or 5-fluorouracil. We also analyzed small studies proposing combination treatments. Almost all studies reported an excellent clinical outcome, with a low risk of relapses in time. Conclusions: Resection of the lesion remains the gold-standard treatment for SCC. When this approach is not feasible, local chemotherapy may represent a treatment alternative, and it may also be associated with radiotherapy or systemic chemotherapy.

scholarly journals Neurological manifestations and neuroimaging findings in patients with SARS-CoV2—a systematic review

2021 ◽  
Vol 57 (1) ◽  
Author(s):  
Nikita Mohan ◽  
Muhammad Ali Fayyaz ◽  
Christopher del Rio ◽  
Navpreet Kaur Rajinder Singh Khurana ◽  
Sampada Sandip Vaidya ◽  
...  
Keyword(s):  
Neurological Diseases ◽  
Case Reports ◽  
Healthcare Providers ◽  
Case Series ◽  
Altered Mental Status ◽  
Common Finding ◽  
Cochrane Library ◽  
Neurological Manifestations ◽  
The Cochrane Library ◽  
Ct And Mri

Abstract Background The COVID-19 pandemic has drastically affected everyone in a hit or miss manner. Since it began, evidence of the neuro-invasive potential of the virus has been intensifying significantly. Several pathways have been hypothesized to elucidate the neurotropic nature of SARS-CoV2. It is the need of the hour to collect vital information. Objective To evaluate and correlate the neuro-radiological and neurological manifestations in patients diagnosed with SARS-CoV2. To identify neuro-invasive pathways of COVID infection. Methods Relevant studies were identified through four databases—the Cochrane Library, PubMed, Science Direct, and Web of Science. These were searched using relevant keywords—“COVID-19,” “SARS-CoV2,” “neurological manifestations,” “neuroimaging,” “CT,” and “MRI.” Relevant articles were screened according to a pre-defined inclusion and exclusion criteria from December 2019 to August 2020. Results Our review included a total of 63 full text publications with 584 patients, composed mainly of observational studies, case reports, and case series. The most common neurological manifestations associated with COVID-19 were altered mental status, stroke, and paralysis. About 17.85% patients who underwent neuroimaging were found to be having ischemic changes suggestive of a stroke. This was followed by hemorrhagic changes as the second most common finding. The most commonly involved vessel was the Middle Cerebral Artery. Besides stroke, we found that SARS-CoV2 could be the cause for new-onset seizures, Guillain-Barre Syndrome, encephalitis, and many other severe neurological diseases. Conclusion The information that we have obtained so far will prove dynamic to healthcare providers working against the COVID-19 pandemic. It is necessary to be aware of these atypical neurological findings for the early diagnosis and treatment of COVID-19 infected patients. However, to completely understand the connection between SARS-CoV2 and the nervous system, further research is necessary.

Localized Juvenile Spongiotic Gingival Hyperplasia : a Case Series

Dental Update ◽  
2020 ◽  
Vol 47 (2) ◽  
pp. 162-164
Author(s):  
Thomas Saunsbury ◽  
Tim Hodgson ◽  
Barbara Carey
Keyword(s):  
Clinical Relevance ◽  
Patient Management ◽  
Case Series ◽  
Histopathological Diagnosis ◽  
Gingival Hyperplasia ◽  
Oral Medicine ◽  
Medicine Clinic ◽  
Dental Hospital

Localized juvenile spongiotic gingival hyperplasia is a relatively new histopathological diagnosis, presenting as a localized erythematous lesion of the anterior attached gingivae. Presenting in a peri-pubertal age, this condition is often misdiagnosed as ‘puberty gingivitis’. Here, two cases presenting to the Joint Paediatric-Oral Medicine clinic at the Eastman Dental Hospital are discussed. CPD/Clinical Relevance: Localized juvenile spongiotic gingival hyperplasia is a novel diagnosis, and one that is currently under-reported. Increased awareness of this condition is required for appropriate patient management.

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