scholarly journals A Bibliometric Review of Publications on Oxidative Stress and Chemobrain: 1990–2019

Antioxidants ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 439
Author(s):  
Taylor McElroy ◽  
Antiño R. Allen
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Central Nervous System ◽  
Web Of Science ◽  
Breast Cancer Patients ◽  
Chemotherapy Treatment ◽  
The Usa ◽  
Bibliometric Review ◽  
The Subject ◽  
The Web

Oxidative stress is considered one of the possible mechanisms behind chemobrain or the cognitive dysfunction persistent after chemotherapy treatment. Breast cancer patients have reported chemobrain symptoms since the 1990s. In this present bibliometric review, we employed the VOSviewer tool to describe the existing landscape on literature concerning oxidative stress, breast cancer chemotherapies, and chemobrain. As of 2019, 8799 papers were listed in the Web of Science database, with more than 900 papers published each year. As expected, terms relating to oxidative stress, mitochondria, breast cancer, and antioxidants have occurred very often in the literature throughout the years. In recent years, there has been an increase in the occurrence of terms related to nanomedicine. Only within the last decade do the keywords ‘brain’, ‘blood-brain barrier’, and ‘central nervous system’ appear, reflecting an increased interest in chemobrain. China has become the most prolific producer of oxidative stress and chemotherapy related papers in the last decade followed by the USA and India. In conclusion, the subject of oxidative stress as a mechanism behind chemotherapies’ toxicities is an active area of research.

scholarly journals A Bibliometric Analysis of Cyclophosphamide, Methotrexate, and Fluorouracil Breast Cancer Treatments: Implication for the Role of Inflammation in Cognitive Dysfunction

2021 ◽  
Vol 8 ◽  
Author(s):  
Christa Corley ◽  
Antiño R. Allen
Keyword(s):  
Breast Cancer ◽  
Side Effects ◽  
Cognitive Dysfunction ◽  
Breast Cancer Patients ◽  
Chemotherapy Treatment ◽  
Cancer Treatments ◽  
The Usa ◽  
Bibliometric Review ◽  
Long Term Survivors

Inflammation is considered one of the possible mechanisms behind long-term cognitive dysfunction persistent after chemotherapy treatment. The chemotherapy combination of cyclophosphamide, methotrexate, and fluorouracil (CMF) was one of the older methods of treating breast cancer patients. Decades later, these patients still report experiencing cognitive side effects. In this present bibliometric review, we applied the VOSviewer tool to describe the existing landscape on literature concerning inflammation as it relates to CMF and cognitive dysfunctions. As time progressed, we saw an increase in interest in the topic. By the mid-2010s there were approximately 1,000 publications per year. Terms related to the brain and CNS did not appear until the later years, and terms related to inflammation and breast cancer were very prevalent throughout the three decades. Also, in more recent years, inflammatory markers and plant-derived compounds used to alleviate side effects of the inflammatory response appeared in the search results. The USA remained the most prolific producer of CMF-, inflammation-, and cognitive dysfunction-related papers throughout the three decades followed by Asia and Europe. As research of cognitive dysfunction caused by inflammation due to chemotherapy treatment progresses, more opportunities emerge for therapeutic methods to improve the quality of life for long-term survivors.

scholarly journals A Bibliometric Review of the Keap1/Nrf2 Pathway and its Related Antioxidant Compounds

Antioxidants ◽  
2019 ◽  
Vol 8 (9) ◽  
pp. 353 ◽  
Author(s):  
Ana Paunkov ◽  
Dionysios V. Chartoumpekis ◽  
Panos G. Ziros ◽  
Gerasimos P. Sykiotis
Keyword(s):  
Web Of Science ◽  
Research Field ◽  
Antioxidant Compounds ◽  
Nrf2 Pathway ◽  
The Past ◽  
Reverse Pattern ◽  
The Usa ◽  
Bibliometric Review ◽  
The Subject ◽  
Active Research

Nrf2 is a master transcriptional regulator of antioxidant and cytoprotective pathways. Currently in its third decade, research on Nrf2 has expanded to encompass not only basic but also clinical studies. In the present bibliometric review, we employed the VOSviewer tool to describe the existing Nrf2 literature landscape. As of July 2019, 11,931 papers on Nrf2 were listed in the “Web of Science” database, with more than 1000 new papers published each year. As expected, terms related to oxidative stress and antioxidant molecules occur very often in the Nrf2 literature throughout the years. Interestingly, there is also a gradual increase in the occurrence of terms related to diseases or to natural compounds, the most prominent being sulforaphane, curcumin, and resveratrol that modulate the Nrf2 pathway. Going beyond molecular biology/biochemistry and related fields, Nrf2 research has begun to spread into more clinical areas like endocrinology/metabolism, cardiology, and nephrology, likely reflecting an increased interest in clinical applications of Nrf2 pathway activators. China has become the most prolific producer of Nrf2 papers the last five years followed by the USA and Japan, a reverse pattern compared to the past. In conclusion, Nrf2 is the subject of a globally active research field that keeps growing and extends from bench to bedside.

scholarly journals Bibliometric Analysis of Studies Conducted between 2015-2019 on the Flipped Classroom Model

2020 ◽  
Vol 7 (1) ◽  
pp. 163
Author(s):  
Recep Çakır ◽  
Volkan Sayın ◽  
Sümeyye Bektaş
Keyword(s):  
Bibliometric Analysis ◽  
Research Method ◽  
Flipped Classroom ◽  
Web Of Science ◽  
Application Process ◽  
The Usa ◽  
Flipped Classrooms ◽  
Publication Language ◽  
The Subject ◽  
The Web

One of the reflections of technology to education is the flipped classroom model. In The Flipped Classroom model, the lecture process on a subject is delivered at home, while the application process that is related to the subject is in the class. The purpose of this study is to examine the trends in recent years via bibliometric results of articles on the use of flipped classrooms in education. For this aim, we investigated a total of 2955 publications on the flipped classroom obtained from the Web of Science database. Then, a bibliometric analysis of the publications was carried out in this study of qualitative research method. The publications have been examined in terms of some bibliometric variables and are presented descriptively. We performed a content analysis using tables and the VOSviewer program. According to the results, the most commonly used keywords in the research are the “flipped classroom learning” and “active learning”, and the publication language is generally English.  The most common types of documents are papers and articles. Valencia Polytechnic University is the most contributing institution in its field of study.  The most active countries in terms of the number of studies are the USA and China.

scholarly journals Musculoskeletal Risks: RULA Bibliometric Review

2020 ◽  
Vol 17 (12) ◽  
pp. 4354 ◽  
Author(s):  
Marta Gómez-Galán ◽  
Ángel-Jesús Callejón-Ferre ◽  
José Pérez-Alonso ◽  
Manuel Díaz-Pérez ◽  
Jesús-Antonio Carrillo-Castrillo
Keyword(s):  
Core Collection ◽  
Web Of Science ◽  
Social Assistance ◽  
Technological Advancement ◽  
The Usa ◽  
Bibliometric Review ◽  
Number Of Publications ◽  
The Web ◽  
Research Studies

The objective of this study was to reveal RULA method applications in terms of the knowledge, country, year and journal categories. The search was performed using the “Web of Science Core Collection”. The period from 1993 to April 2019 was selected. Eight hundred nine results were obtained, of which 226 were used. The largest number of publications was determined to be in the fields of industry and health and social assistance, which coincides with the OWAS and Standardized Nordic Questionnaire methods. By country, the USA stands out for its greater number of research studies and categories that are encompassed. By date, 2016 was the year when more studies were carried out, again coinciding with the Standardized Nordic Questionnaire. By journal, “Work—A Journal of Prevention Assessment and Rehabilitation” is highlighted, as it is for the REBA method as well. It was concluded that RULA can be applied to workers in different fields, usually in combination with other methods, while technological advancement provides benefits for its application.

scholarly journals Systemic Manifestations of the Periodontal Disease: A Bibliometric Review

Molecules ◽  
2020 ◽  
Vol 25 (19) ◽  
pp. 4508
Author(s):  
Paras Ahmad ◽  
Anas Imran Arshad ◽  
Elena Della Bella ◽  
Zohaib Khurshid ◽  
Martin Stoddart
Keyword(s):  
Clinical Trials ◽  
Periodontal Disease ◽  
Literature Search ◽  
Web Of Science ◽  
Citation Count ◽  
Current Trends ◽  
The Usa ◽  
Bibliometric Review ◽  
Systemic Manifestations ◽  
The Web

This bibliometric review aimed to identify and analyze the top 100 most-cited publications on the systemic manifestations of periodontal disease (PD). A literature search was performed using the Web of Science (WoS) ‘All Databases’, without any restriction of language, publication year, or study design. Of 4418 articles, the top 100 were included based on their citation count. After downloading the full texts, their bibliometric information was extracted and analyzed. The citation counts for the top 100 articles ranged from 156 to 4191 (median 217). The most productive years were 2003 and 2005, with 20 articles on the list. Majority of the articles were published in the Journal of Periodontology (n = 25). The top 100 articles were generated primarily from the USA (n = 61). Most of the publications were clinical trials (n = 27) and focused on the cardiovascular manifestations of PD (n = 31). Most of the articles were within the evidence level V (n = 41). A total of 58 studies received funding and the most frequently used keyword in the top articles was “periodontal disease” (n = 39). The current citation analysis presents insights into the current trends in the systemic manifestations of periodontal disease.

scholarly journals Antioxidants for the Treatment of Breast Cancer: Are We There Yet?

Antioxidants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 205
Author(s):  
Carmen Griñan-Lison ◽  
Jose L. Blaya-Cánovas ◽  
Araceli López-Tejada ◽  
Marta Ávalos-Moreno ◽  
Alba Navarro-Ocón ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Cancer Progression ◽  
Redox Homeostasis ◽  
Breast Carcinogenesis ◽  
Breast Cancer Patients ◽  
Chemopreventive Agents ◽  
Low Degree ◽  
Potential Use

Breast cancer is the most frequent cancer and the leading cause of cancer death in women. Oxidative stress and the generation of reactive oxygen species (ROS) have been related to cancer progression. Compared to their normal counterparts, tumor cells show higher ROS levels and tight regulation of REDOX homeostasis to maintain a low degree of oxidative stress. Traditionally antioxidants have been extensively investigated to counteract breast carcinogenesis and tumor progression as chemopreventive agents; however, there is growing evidence indicating their potential as adjuvants for the treatment of breast cancer. Aimed to elucidate whether antioxidants could be a reality in the management of breast cancer patients, this review focuses on the latest investigations regarding the ambivalent role of antioxidants in the development of breast cancer, with special attention to the results derived from clinical trials, as well as their potential use as plausible agents in combination therapy and their power to ameliorate the side effects attributed to standard therapeutics. Data retrieved herein suggest that antioxidants play an important role in breast cancer prevention and the improvement of therapeutic efficacy; nevertheless, appropriate patient stratification based on “redoxidomics” or tumor subtype is mandatory in order to define the dosage for future standardized and personalized treatments of patients.

scholarly journals A global bibliometric analysis of research on microplastics from 2004 to 2020

2021 ◽  
Author(s):  
Ming Li ◽  
Binshuo Liu ◽  
Lei Wu ◽  
Shuang Zhong ◽  
Chunqing Wang ◽  
...  
Keyword(s):  
Core Collection ◽  
Environmental Science ◽  
Web Of Science ◽  
Environmental Problem ◽  
Research Trends ◽  
Research Directions ◽  
Bibliographic Records ◽  
Significant Interest ◽  
The Usa ◽  
The Web

Abstract Microplastics (MPs) pollution has garnered significant interest as a serious environmental problem. To date, a large amount of research has been published on this topic. We analyzed the related studies to assess the global developments of MPs regarding the evolution, research trends, and hotspots by bibliometric. A total of 2,872 bibliographic records were retrieved from the Web of Science Core Collection, and CiteSpace 5.4 was used for bibliometrics. The results visually displayed the contributing countries, institutions, authors, keywords, and potential research directions in the MPs fields. The scientific developments in this field began in 2004 and have accelerated considerably since 2012. China and the USA are the leading countries in MPs research. The research on MPs is multidisciplinary and involves Ecology, Chemistry, Molecular Biology, Environmental Science, and Oceanography. Among these, Oceanography was the most connected with MPs and was the most well-developed. Overall, we mapped the development of MPs research and attempted a comprehensive discussion and understanding of scientific advances, as well as the progress made.

scholarly journals Roles of Superoxide dismutase(SOD) , Malondialdehyde (MDA), 8-iso-prostaglandinF2α ( 8-iso-PGF2α)as oxidative stress in development and progression of Brest cancer in Iraqi females patients

2020 ◽  
Vol 25 (1) ◽  
pp. 1-4
Author(s):  
Ferdous Abbas Jabir ◽  
Ahmed Sabah Shaker
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Cancer Patients ◽  
Antioxidant Defenses ◽  
Blood Levels ◽  
P Value ◽  
Oxygen Species ◽  
Breast Cancer Patients ◽  
Markers Of Oxidative Stress ◽  
The Mean

               Oxidative stress occurs as a result of disturbance in the balance between the production of reactive oxygen species (free radicals) and antioxidant defenses. Markers of oxidative stress were measured the markers of oxidative stress in breast cancer patients after diagnosis of breast cancer and compared these plasma blood levels controls This study was conducted to three markers of oxidative stress ;these are (SOD) enzyme ,malondialdehyde (MDA)and8-iso-prostaglandinF2α plasma of patients with breast cancer and compare with controls .In this study ;  the mean MDA (ng/ml) levels for the breast cancer patients and the controls were55.91±3.31 and40.61±3.76  respectively, while the SOD (pg/ml) levels were1530.37±80.4 and1851.4 9±93.65  respectively and the 8-iso-PGF2α (ng/ml ) levels were 40.16±3.31 and 30.16±2.34  difference of the mean were statistically significant (p value <0.05).                                                                                                                       

scholarly journals Spatial Analysis for Landscape Changes: A Bibliometric Review

2021 ◽  
Vol 11 (21) ◽  
pp. 10078
Author(s):  
Maria Danese ◽  
Dario Gioia
Keyword(s):  
Spatial Analysis ◽  
Web Of Science ◽  
Research Topic ◽  
Point Of View ◽  
Research Trend ◽  
Landscape Changes ◽  
Bibliometric Review ◽  
Number Of Citations ◽  
The Web

The main aim of this study is to analyze from a bibliometric point of view the research trend in spatial analysis for landscape changes using the records published in the Web of Science database in the last twenty years. Several parameters such as documents published per year, sources of documents, number of citations as well as VOSviewer software and GIS are used for the analysis of different metrics such as the number of citations, co-authorship network, and keyword occurrences. Analysis of the number of papers, their keywords, and authorships countries shows the research trend in the specific topics of the spatial analysis for landscape changes and consequently can constitute a benchmark for researchers who approach this research topic.

Sign in / Sign up

Export Citation Format

Share Document