scholarly journals Optimal WovenEndo Bridge (WEB) Device Size Selection Using Automated Volumetric Software

2021 ◽  
Vol 11 (7) ◽  
pp. 901
Author(s):  
Sameer Ansari ◽  
Cynthia B. Zevallos ◽  
Mudassir Farooqui ◽  
Andres Dajles ◽  
Sebastian Schafer ◽  
...  
Keyword(s):  
Imaging Modality ◽  
Pearson Correlation ◽  
Three Dimensional ◽  
Flow Density ◽  
Size Selection ◽  
Device Implantation ◽  
Aneurysm Volume ◽  
Web Device ◽  
Device Size ◽  
Implantation Success

Introduction: Selecting the appropriate Woven EndoBridge (WEB) device sizing for the treatment of wide-neck bifurcation aneurysms (WNBAs) remains challenging. The aim of this study was to evaluate different volumetric-based imaging methodologies to predict an accurate WEB device size selection to result in a successful implantation. Methods: All consecutive patients treated with WEB devices for intracranial aneurysms from January 2019 to June 2020 were included. Aneurysm dimensions to calculate aneurysm volumes were measured using three different modalities: automated three-dimensional (3D) digital subtraction angiography (DSA), manual 3D DSA, and two-dimensional (2D) DSA. The device–aneurysm volume (DAV) ratio was defined as device volume divided by the aneurysm volume. WEB volumes and the DAV ratios were used for assessing the device implantation success and follow-up angiographic outcomes at six months. Pearson correlation, Wilcoxon Rank Sum test, and flow density approximations were used for estimating the WEB volumes and the imaging modality volumes for successful implantation. Results: A total of 41 patients with 43 aneurysms were included in the study. WEB device and aneurysm volume correlation coefficient was highest for 3D automatic (r = 0.943), followed by 3D manual (r = 0.919), and 2D DSA (r = 0.882) measurements. Measured median volumes were significantly different for 3D automatic and 2D DSA (p = 0.017). The highest rate of successful implantation (87.5%) was between 0.6 and 0.8 DAV ratio. Conclusion: Pre-procedural assessment of DAV ratios may increase WEB device implantation success. Our results suggest that volumetric measurements, especially using automated 3D volumes of the aneurysms, can assist in accurate WEB device size selection.

Volume-based sizing of the Woven EndoBridge (WEB) device: A preliminary assessment of a novel method for device size selection

2021 ◽  
pp. 159101992098768
Author(s):  
Kevin A Shah ◽  
Timothy G White ◽  
Ina Teron ◽  
Thomas Link ◽  
Amir R Dehdashti ◽  
...  
Keyword(s):  
Pearson Correlation ◽  
Three Dimensional ◽  
Size Selection ◽  
Significant Difference ◽  
Width Measurements ◽  
Woven Endobridge ◽  
Web Device ◽  
The Web ◽  
Web Size

Introduction Accurate sizing of the Woven EndoBridge (WEB) device is of critical importance as it determines procedural safety and successful occlusion of wide neck bifurcation aneurysms. The aim of this study was to assess the ability of aneurysm volume to assist in accurate WEB size selection. Methods All patients with an intracranial aneurysm treated with the WEB SL or WEB SLS device between March 2019 and October 2019 were identified for this retrospective study. Aneurysm volumes were calculated with auto-segmentation using a three-dimensional volume rendering program on an independent Syngo workstation (Siemens Healthineers AG). Pearson correlation coefficients were calculated for aneurysm auto-segmented volumes and WEB volumes, as well as for aneurysm height × width and WEB height × width. Follow-up angiographic outcomes were collected at 6–9 months post-procedure. Results Twenty-nine aneurysms were evaluated by 3D rotational angiography. The correlation coefficient with WEB size was larger for auto-segmented aneurysm volumes (r = 0.979) compared to height × width measurements (r = 0.867). Using Fisher r-to-z transformations, we found the difference between the two correlations to be statistically significant (p = 0.0007). Follow-up angiography available in 13 subjects demonstrated an 85% complete aneurysm occlusion rate. Conclusion Aneurysm volumes are highly correlated with WEB volumes, with auto-segmentation volumes displaying statistically significant difference against conventional height by width measurements. These results suggest that volumetric measurements of aneurysm size provide a useful adjuvant measure to assist in appropriate size selection of the WEB device.

scholarly journals 475 Is left atrial appendage device compression rate a predictor of incomplete occlusion in patients undergoing watchman device implantation?

2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Michele Magnocavallo ◽  
Domenico Giovanni Della Rocca ◽  
Carlo Lavalle ◽  
Cristina Chimenti ◽  
Gianni Carola ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Appendage ◽  
Imaging Modality ◽  
Accurate Method ◽  
Atrial Appendage ◽  
Device Implantation ◽  
Watchman Device ◽  
Device Size ◽  
Original Device

Abstract Aims Transesophageal echocardiography (TEE) is a standard peri-procedural imaging modality in patients undergoing percutaneous left atrial appendage (LAA) occlusion. An accurate device sizing is pivotal to assess stability and achieve successful closure. In this prospective study, we sought to evaluate the correlation between Watchman device compression rates (DCRs) and risk of incomplete LAA occlusion at follow-up in patients undergoing Watchman device implantation. Methods and results Two-dimensional TEE via a commercially available transducer (Vivid, Philips) was performed during the procedure and within 3 months after the procedure. LAA size, morphology, and DCRs [(original device size—size after deployment)/original device size; %] were assessed in a mid-oesophageal view at 0°, 45°, 90° and 135°, according to company recommendations. Residual leaks ≥ 3 mm were classified as significant. Between 2016 and 2018, 116 patients underwent LAA occlusion with a Watchman device at our institution. The mean age was 74 ± 9 years and 60.4% (n = 70) were males. The average CHA2DS2-VASc and HAS-BLED scores were 4.7 ± 1.7 and 2.5 ± 1.1, respectively. The final device size was 21 mm in 11 (9.5%) patients, 24 mm in 28 (24.1), 27 mm in 27 (23.3%), 30 mm in 26 (22.4%), and 33 mm in 24 (20.7). At follow-up TEE, 16 (13.8%) patients were found to have a significant (≥3 mm) residual leak. The average DCRs measured at different angles in patients with and without leak were not significantly different (24 ± 8% vs. 26 ± 7% at 0°, P = 0.47; 23 ± 9% vs. 25 ± 7% at 45°, P = 0.58; 23 ± 8% vs. 23 ± 6% at 90°, P = 0.61; 22 ± 8% vs. 21 ± 7% at 135°, P = 0.61). At receiver operating characteristic (ROC) analysis, the areas under the curve to discriminate between patients with/without leak were 0.58, 0.57, 0.55, and 0.46 for DCRs measured at 0°, 45°, 90°, and 135° angles. Conclusions Peri-procedural assessment of DCRs does not appear to be an accurate method to predict LAA complete occlusion in patients undergoing Watchman device implantation.

scholarly journals A novel three-dimensional echocardiographic method for device size selection in patients undergoing ASD trans-catheter closure

2019 ◽  
Vol 72 (1) ◽  
Author(s):  
Alaa Roushdy ◽  
Aya El sayegh ◽  
Yasmin Abdelrazek Ali ◽  
Hebattalla Attia ◽  
Azza El fiky ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Accurate Method ◽  
Maximum Diameter ◽  
Regression Equations ◽  
Strong Positive Correlation ◽  
Device Closure ◽  
Size Selection ◽  
Significant Difference ◽  
Catheter Closure ◽  
Device Size

Abstract Background Proper device size selection is a crucial step for successful ASD device closure. The current gold standard for device size selection is balloon sizing. Balloon sizing can be tedious, time consuming and increase fluoroscopy and procedure times as well as risk of complications. We aimed to establish a simple and accurate method for device size selection using three-dimensional echocardiographic interrogation of the ASD.This is a prospective observational study conducted over a period of 12 months. All patients underwent 2D TTE, three-dimensional echocardiographic assessment of the IAS and transesophageal echocardiogram. Comparison between echocardiographic variables was done using independent sample t test. Linear correlation was established between three dimensional echocardiographic variables and respective variables of device size and 2D TTE and TEE measurements. Results The study included 50 patients who underwent successful ASD device closure with properly sized device. There was no significant difference between 3D ASD maximum diameter and all diameters measured by TTE and TEE. There was a strong positive correlation between device size used for closure and both 3D measured ASD area (r = 0.907, P<0.0001) and 3D measured ASD circumference (r = 0.917, P<0.0001). Two regression equations were generated to determine proper device size where Device size = 10.8 + [3.95 x 3D ASD area] and Device size = [3.85 x 3D ASD circumference] -1.02 Conclusion Three-dimensional echocardiogram can provide a simple and accurate method for device size selection in patients undergoing ASD device closure using either 3D derived ASD area or ASD circumference

A comparison between the CS-TOF and the CTA/DSA for WEB device management

2021 ◽  
pp. 159101992110147
Author(s):  
Oktay Algin ◽  
Gokhan Yuce ◽  
Ural Koc ◽  
Gıyas Ayberk
Keyword(s):  
Mr Angiography ◽  
Three Dimensional ◽  
Morphological Parameters ◽  
Perfect Agreement ◽  
Device Management ◽  
Web Device ◽  
Sensing Time ◽  
The Web

Purpose There is no study on the role of three-dimensional compressed sensing time of flight MR angiography (3D-CS-TOF) in the management of the WEB device. We evaluated the efficacy of 3-tesla 3D-CS-TOF for the management and follow-up of the WEB device implantations. Materials and methods Seventy-three aneurysms of 69 patients treated with the WEB device were retrospectively examined. Morphological parameters and embolization results of the aneurysms were assessed and compared on 3D-CS-TOF, CTA, and DSA images. Results Occluded, neck remnant, and recurrent aneurysms were observed in 61 (83.6%), 7 (9.6%), and 5 (6.8%) aneurysms, respectively. Inter- and intra-reader agreement values related to aneurysm size measurements were perfect. Aneurysms size, age, and proximal vessel tortuosity were negatively correlated with the visibility of the aneurysms and parent vessels on 3D-CS-TOF images (p = 0.043; p = 0.032; p < 0.001, respectively). Subarachnoid hemorrhage and age are associated with 3D-CS-TOF artifacts (p = 0.031; p = 0.005, respectively). 3D-CS-TOF findings are in perfect agreement with DSA or CT angiography (CTA) results (p < 0.001). Conclusion According to our results, 3D-CS-TOF can be an easy, fast, and reliable alternative for the management or follow-up of WEB assisted embolization.

scholarly journals The patellofemoral morphology and the normal predicted value of tibial tuberosity-trochlear groove distance in the Chinese population

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Zhe Li ◽  
Guanzhi Liu ◽  
Run Tian ◽  
Ning Kong ◽  
Yue Li ◽  
...  
Keyword(s):  
Individual Differences ◽  
Chinese Population ◽  
Pearson Correlation ◽  
Three Dimensional ◽  
Correlation Coefficients ◽  
Tibial Tuberosity ◽  
Trochlear Groove ◽  
Lasso Regression ◽  
Cross Sectional ◽  
Anterior Posterior

Abstract Background Our objective was to obtain normal patellofemoral measurements to analyse sex and individual differences. In addition, the absolute values and indices of tibial tuberosity-trochlear groove (TT-TG) distances are still controversial in clinical application. A better method to enable precise prediction is still needed. Methods Seventy-eight knees of 78 participants without knee pathologies were included in this cross-sectional study. A CT scan was conducted for all participants and three-dimensional knee models were constructed using Mimics and SolidWorks software. We measured and analysed 19 parameters including the TT-TG distance and dimensions and shapes of the patella, femur, tibia, and trochlea. LASSO regression was used to predict the normal TT-TG distances. Results The dimensional parameters, TT-TG distance, and femoral aspect ratio of the men were significantly larger than those of women (all p values < 0.05). However, after controlling for the bias from age, height, and weight, there were no significant differences in TT-TG distances and anterior-posterior dimensions between the sexes (all p values > 0.05). The Pearson correlation coefficients between the anterior femoral offset and other indexes were consistently below 0.3, indicating no relationship or a weak relationship. Similar results were observed for the sulcus angle and the Wiberg index. Using LASSO regression, we obtained four parameters to predict the TT-TG distance (R2 = 0.5612, p < 0.01) to achieve the optimal accuracy and convenience. Conclusions Normative data of patellofemoral morphology were provided for the Chinese population. The anterior-posterior dimensions of the women were thicker than those of men for the same medial-lateral dimensions. More attention should be paid to not only sex differences but also individual differences, especially the anterior condyle and trochlea. In addition, this study provided a new method to predict TT-TG distances accurately.

scholarly journals Rapid imaging of special nuclear materials for nuclear nonproliferation and terrorism prevention

2021 ◽  
Vol 7 (21) ◽  
pp. eabg3032
Author(s):  
Jana Petrović ◽  
Alf Göök ◽  
Bo Cederwall
Keyword(s):  
Nuclear Physics ◽  
Imaging Modality ◽  
Three Dimensional ◽  
Nuclear Fission ◽  
Machine Learning Techniques ◽  
Nuclear Materials ◽  
Prototype System ◽  
Fast Time ◽  
Gamma Emission ◽  
Special Nuclear Materials

We introduce a neutron-gamma emission tomography (NGET) technique for rapid detection, three-dimensional imaging, and characterization of special nuclear materials like weapons-grade plutonium and uranium. The technique is adapted from fundamental nuclear physics research and represents a previously unexplored approach to the detection and imaging of small quantities of these materials. The method is demonstrated on a radiation portal monitor prototype system based on fast organic scintillators, measuring the characteristic fast time and energy correlations between particles emitted in nuclear fission processes. The use of these correlations in real time in conjunction with modern machine learning techniques provides unprecedented imaging efficiency and high spatial resolution. This imaging modality addresses global security threats from terrorism and the proliferation of nuclear weapons. It also provides enhanced capabilities for addressing different nuclear accident scenarios and for environmental radiological surveying.

scholarly journals Magnetic particle imaging of particle dynamics in complex matrix systems

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Sebastian Draack ◽  
Meinhard Schilling ◽  
Thilo Viereck
Keyword(s):  
Magnetic Particle ◽  
Imaging Modality ◽  
Three Dimensional ◽  
Local Environment ◽  
Relaxation Mechanism ◽  
Harmonic Spectrum ◽  
Magnetic Particle Imaging ◽  
Matrix Interactions ◽  
Tracer Distribution ◽  
Particle Imaging

Abstract Magnetic particle imaging (MPI) is a young imaging modality for biomedical applications. It uses magnetic nanoparticles as a tracer material to produce three-dimensional images of the spatial tracer distribution in the field-of-view. Since the tracer magnetization dynamics are tied to the hydrodynamic mobility via the Brownian relaxation mechanism, MPI is also capable of mapping the local environment during the imaging process. Since the influence of viscosity or temperature on the harmonic spectrum is very complicated, we used magnetic particle spectroscopy (MPS) as an integral measurement technique to investigate the relationships. We studied MPS spectra as function of both viscosity and temperature on model particle systems. With multispectral MPS, we also developed an empirical tool for treating more complex scenarios via a calibration approach. We demonstrate that MPS/MPI are powerful methods for studying particle-matrix interactions in complex media.

Acceleration of the EM-like reconstruction method for diffuse optical tomography with ordered-subsets method

2014 ◽  
Vol 22 (3) ◽  
Author(s):  
Caifang Wang
Keyword(s):  
Numerical Experiments ◽  
Imaging Modality ◽  
Random Medium ◽  
Optical Tomography ◽  
Back Propagation ◽  
Three Dimensional ◽  
Diffuse Optical Tomography ◽  
Optical Parameters ◽  
Reconstruction Method ◽  
Boundary Measurements

Abstract.Diffuse optical tomography (DOT) is an optical imaging modality, which provides the spatial distribution of the optical parameters inside a random medium. A propagation back-propagation method named EM-like reconstruction method for stationary DOT problem has been proposed yet. This method is really time consuming. Hence the ordered-subsets (OS) technique for this reconstruction method is studied in this paper. The boundary measurements of DOT are grouped into nonoverlapping and overlapping ordered sequence of subsets with random partition, sequential partition and periodic partition, respectively. The performance of OS methods is compared with the standard EM-like reconstruction method with two-dimensional and three-dimensional numerical experiments. The numerical experiments indicate that reconstruction of nonoverlapping subsets with periodic partition, overlapping subsets with periodic partition and standard EM-like method provide very similar acceptable reconstruction results. However, reconstruction of nonoverlapping subsets with periodic partition spends a minimum of time to get proper results.

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