scholarly journals Changes in Ultraviolet Radiation Exposure to the Ocular Region: A Population-Based Study

Cancers ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 719 ◽  
Author(s):  
Ezekiel Weis ◽  
Sebastian Q. Vrouwe ◽  
David B. LeBaron ◽  
Matthew B. Parliament ◽  
Jerry Shields ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Ultraviolet Radiation ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Group Versus ◽  
Population Based ◽  
Incidence Rates ◽  
The Body ◽  
Incidence Trends ◽  
Males And Females

In contrast to the well-established association between ultraviolet radiation (UVR) exposure and skin cancers, the relationship between UVR and uveal malignant melanoma (UM) remains controversial. To address this controversy, we evaluated the incidence rates of cutaneous malignancies in the eyelids as a proxy for UVR exposure in the ocular region using a population-based cancer registry. Overall, 74,053 cases of eyelid basal cell carcinoma (BCC) and 7890 cases of melanoma over a 26-year period (1982–2007) were analyzed. The incidence of eyelid basal cell carcinoma and uveal melanoma remained stable, whereas other cutaneous areas demonstrated an increase in the rates. A comparability test demonstrated that BCC incidence trends were significantly different between the eyelid versus both chronically exposed (males p = 0.001; females p = 0.01) and intermittently exposed skin (males and females, p = 0.0002), as well as the skin of the face (males p = 0.002; females p = 0.02). Similarly, melanoma trends were significantly different between the UM group versus both chronically exposed cutaneous melanoma (CM) (males p = 0.001; females p = 0.04) and intermittently exposed CM (males p = 0.005), as well as facial skin CM (males and females p = 0.0002). The discrepancy of cancer incidence between tumors in the peri-ocular region versus the rest of the body suggests that the peri-ocular region might have a different or unique exposure pattern to ultraviolet radiation.

Incidence of Basal Cell Carcinoma in Cohort of Mayak Workers

2021 ◽  
Vol 66 (5) ◽  
pp. 91-94
Author(s):  
M. Bannikova ◽  
T. Azizova
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Incidence Rate ◽  
Basal Cell ◽  
Linear Trend ◽  
Incidence Rates ◽  
Study Cohort ◽  
Absolute Growth ◽  
Study Population ◽  
Males And Females

Results: To estimate incidence rates for basal cell carcinoma (BSC) following chronic occupational radiation exposure. Conclusion:The study cohort included 22,377 workers (25.4 % of females) of the nuclear production facility, Mayak Production Association (PA), who had been hired in 1948–1982. Gamma doses of external exposure were provided by the Mayak Workers Dosimetry System – 2013 (MWDS–2013). The cohort was followed up until 31.12.2018. Results: By the end of the follow-up period 293 BSC cases were registered in the study cohort. BSC incidence rates significantly increased with increasing attained age of workers. The highest BSC incidence rate was observed in the age group above 70 years, both for males and females. The study found a significant increasing linear trend for standardized incidence rates for both males and females; approximation confidence factors were R2 = 0.82 and R2 = 0.95, respectively. The majority of BSC cases in the study cohort were registered in 1994–2018 (71.12 % in males and 81.13 % in females). The component analysis demonstrated that the absolute growth in the BSC incidence rate in both males and females was due to changes in the age structure of the study population and the risk of the disease. Conclussion: BSC incidence rates were significantly higher in males externally exposed to gamma rays at cumulative skin absorbed doses 0.2–0.5 Gy, 0.5–1.0 Gy and above 1.0 Gy compared to those exposed at doses below 0.1 Gy. In females the corresponding differences were non-significant.

scholarly journals Anatomical Distributions of Basal Cell Carcinoma and Squamous Cell Carcinoma in a Population-Based Study in Queensland, Australia

2017 ◽  
Vol 153 (2) ◽  
pp. 175 ◽  
Author(s):  
Padmini Subramaniam ◽  
Catherine M. Olsen ◽  
Bridie S. Thompson ◽  
David C. Whiteman ◽  
Rachel E. Neale ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Population Based ◽  
Population Based Study

Population-based incidence of basal cell carcinoma in a Spanish Mediterranean area

2009 ◽  
Vol 161 (6) ◽  
pp. 1341-1346 ◽  
Author(s):  
I. Bielsa ◽  
X. Soria ◽  
M. Esteve ◽  
C. Ferrándiz ◽  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Mediterranean Area ◽  
Population Based

scholarly journals Differences in age and topographic distribution of the different histological subtypes of basal cell carcinoma, Taubaté (SP), Brazil

2013 ◽  
Vol 88 (5) ◽  
pp. 726-730 ◽  
Author(s):  
Flavia Regina Ferreira ◽  
Bruna da Costa Pevide ◽  
Rafaela Fabri Rodrigues ◽  
Luiz Fernando Costa Nascimento ◽  
Marcia Lanzoni de Alvarenga Lira
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Skin Color ◽  
Age Of Onset ◽  
The Body ◽  
University Hospital ◽  
Histological Subtype ◽  
Histological Subtypes ◽  
The Mean

BACKGROUND: Basal cell carcinoma is the most common form of cancer in humans. OBJECTIVES: To identify the epidemiology of basal cell carcinoma in Taubaté-SP and verify a possible association between topography and the different histological subtypes of this tumor. METHODS: This was a cross-sectional study conducted at The University Hospital of Taubaté between 01/01/08 and 12/31/09. The study included patients with a confirmed diagnosis of basal cell carcinoma, of both genders, without age restrictions. The variables studied were incidence of basal cell carcinoma, topography, histological subtype, skin color, age and gender. We employed the chi-square test to identify the association between histological subtype and topography, and the student's t test to compare the mean age of onset for the different histological subtypes. RESULTS: The study included 239 individuals. The mean age of the sample was 68.0 years. Male subjects (57.7%) and whites (87.1%) predominated in the study. The predominant histological subtype was nodular (34.7%), followed by the superficial subtype. The most frequent sites of involvement were the head and neck (areas exposed to light), with predominance of the nasal region. The superficial subtype was an exception, as it showed a strong association with unexposed areas like the trunk. The mean age of onset of superficial basal cell carcinoma also differed from that of the other histological subtypes, 63.0 and 69.0 years, respectively. CONCLUSION: The results of this study suggest an association of the superficial histological subtype with younger patients and unexposed areas of the body, linking this type of tumor with a pattern of intermittent sun exposure, more similar to the standard photocarcinogenesis of melanoma.

Basal Cell Carcinoma of the External Auditory Canal – Unusual Site: A Case Report

2020 ◽  
pp. 1-3
Author(s):  
Eman Nagy Mohamed ◽  
Eman Nagy Mohamed ◽  
Ahmed Elshahat
Keyword(s):  
Case Report ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Malignant Tumor ◽  
External Auditory Canal ◽  
Safety Margin ◽  
The Body ◽  
Treatment Result

Malignant tumor originated from external auditory canal (EAC) is very rare with an annual incidence of around 1 per million. Yet, basal cell carcinomas are less frequent than squamous cell carcinomas. Nevertheless, it is difficult to determine if their prognosis is better, as in other areas of the body. Due to the rarity of malignant tumor of EAC, there is no widely accepted treatment modality yet. But basal cell carcinoma, is known to be less aggressive tumor than squamous cell carcinoma and can be removed with a minimal safety margin and has a better treatment result. In this case report, we experienced a case of basal cell carcinoma (BCC) in the EAC, confined in the cartilaginous portion of EAC, presented with intermittent otorrhea and pruritis in the right ear. The patient was treated with local excision of the lesion with a safety margin and direct closure. No recurrence or complications were noted in the first postoperative year.

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